메뉴 건너뛰기




Volumn 304, Issue 10, 2013, Pages

Postnatal development of the endocrine pancreas in mice lacking functional GABAB receptors

Author keywords

gamma; aminobutyrate acid B; Hormones; Islet development; Receptors; Transcription factors

Indexed keywords

4 AMINOBUTYRIC ACID B RECEPTOR; TRANSCRIPTION FACTOR;

EID: 84878561585     PISSN: 01931849     EISSN: 15221555     Source Type: Journal    
DOI: 10.1152/ajpendo.00569.2012     Document Type: Article
Times cited : (5)

References (74)
  • 1
    • 0032525981 scopus 로고    scopus 로고
    • beta-cell-specific inactivation of the mouse Ipf1/Pdx1 gene results in loss of the beta-cell phenotype and maturity onset diabetes
    • Ahlgren U, Jonsson J, Jonsson L, Simu K, Edlund H. beta-cell-specific inactivation of the mouse Ipf1/Pdx1 gene results in loss of the beta-cell phenotype and maturity onset diabetes. Genes Dev 12: 1763-1768, 1998.
    • (1998) Genes Dev , vol.12 , pp. 1763-1768
    • Ahlgren, U.1    Jonsson, J.2    Jonsson, L.3    Simu, K.4    Edlund, H.5
  • 4
    • 77952094047 scopus 로고    scopus 로고
    • Oligodeoxynucleotide IMT504 induces a marked recovery in a streptozotocin-induced model of diabetes in rats: Correlation with an early increase in the expression of nestin and neurogenin 3 progenitor cell markers
    • Bianchi MS, Hernando-Insúa A, Chasseing NA, Rodríguez JM, Elías F, Lago N, Zorzopulos J, Libertun C, Montaner AD, Lux-Lantos VA. Oligodeoxynucleotide IMT504 induces a marked recovery in a streptozotocin-induced model of diabetes in rats: correlation with an early increase in the expression of nestin and neurogenin 3 progenitor cell markers. Diabetologia 53: 1184-1189, 2010.
    • (2010) Diabetologia , vol.53 , pp. 1184-1189
    • Bianchi, M.S.1    Hernando-Insúa, A.2    Chasseing, N.A.3    Rodríguez, J.M.4    Elías, F.5    Lago, N.6    Zorzopulos, J.7    Libertun, C.8    Montaner, A.D.9    Lux-Lantos, V.A.10
  • 5
    • 28444454478 scopus 로고    scopus 로고
    • Expression of gamma-aminobutyric acid B receptor subunits in hypothalamus of male and female developing rats
    • Bianchi MS, Lux-Lantos VA, Bettler B, Libertun C. Expression of gamma-aminobutyric acid B receptor subunits in hypothalamus of male and female developing rats. Brain Res Dev Brain Res 160: 124-129, 2005.
    • (2005) Brain Res Dev Brain Res , vol.160 , pp. 124-129
    • Bianchi, M.S.1    Lux-Lantos, V.A.2    Bettler, B.3    Libertun, C.4
  • 10
    • 25444455671 scopus 로고    scopus 로고
    • Regulation of pancreatic beta-cell mass
    • Bouwens L, Rooman I. Regulation of pancreatic beta-cell mass. Physiol Rev 85: 1255-1270, 2005.
    • (2005) Physiol Rev , vol.85 , pp. 1255-1270
    • Bouwens, L.1    Rooman, I.2
  • 11
    • 77954252193 scopus 로고    scopus 로고
    • Gamma-aminobutyric acid (GABA) is an autocrine excitatory transmitter in human pancreatic beta-cells
    • Braun M, Ramracheya R, Bengtsson M, Clark A, Walker JN, Johnson PR, Rorsman P. Gamma-aminobutyric acid (GABA) is an autocrine excitatory transmitter in human pancreatic beta-cells. Diabetes 59: 1694-1701, 2010.
    • (2010) Diabetes , vol.59 , pp. 1694-1701
    • Braun, M.1    Ramracheya, R.2    Bengtsson, M.3    Clark, A.4    Walker, J.N.5    Johnson, P.R.6    Rorsman, P.7
  • 12
    • 4644278226 scopus 로고    scopus 로고
    • GABAB receptor activation inhibits exocytosis in rat pancreatic beta-cells by G-protein-dependent activation of calcineurin
    • Braun M, Wendt A, Buschard K, Salehi A, Sewing S, Gromada J, Rorsman P. GABAB receptor activation inhibits exocytosis in rat pancreatic beta-cells by G-protein-dependent activation of calcineurin. J Physiol 559: 397-409, 2004.
    • (2004) J Physiol , vol.559 , pp. 397-409
    • Braun, M.1    Wendt, A.2    Buschard, K.3    Salehi, A.4    Sewing, S.5    Gromada, J.6    Rorsman, P.7
  • 13
    • 63049137246 scopus 로고    scopus 로고
    • Slow and steady is the key to beta-cell replication
    • Brennand K, Melton D. Slow and steady is the key to beta-cell replication. J Cell Mol Med 13: 472-487, 2009.
    • (2009) J Cell Mol Med , vol.13 , pp. 472-487
    • Brennand, K.1    Melton, D.2
  • 14
    • 0036190005 scopus 로고    scopus 로고
    • Metabobropic glutamate and GABA(B) receptors contribute to the modulation of glucose-stimulated insulin secretion in pancreatic beta cells
    • Brice NL, Varadi A, Ashcroft SJ, Molnar E. Metabobropic glutamate and GABA(B) receptors contribute to the modulation of glucose-stimulated insulin secretion in pancreatic beta cells. Diabetologia 45: 242-252, 2002.
    • (2002) Diabetologia , vol.45 , pp. 242-252
    • Brice, N.L.1    Varadi, A.2    Ashcroft, S.J.3    Molnar, E.4
  • 17
    • 0037066694 scopus 로고    scopus 로고
    • Quantitative assessment of gene targeting in vitro and in vivo by the pancreatic transcription factor, Pdx1. Importance of chromatin structure in directing promoter binding
    • Chakrabarti SK, James JC, Mirmira RG. Quantitative assessment of gene targeting in vitro and in vivo by the pancreatic transcription factor, Pdx1. Importance of chromatin structure in directing promoter binding. J Biol Chem 277: 13286-13293, 2002.
    • (2002) J Biol Chem , vol.277 , pp. 13286-13293
    • Chakrabarti, S.K.1    James, J.C.2    Mirmira, R.G.3
  • 18
    • 67650718127 scopus 로고    scopus 로고
    • A low protein diet in early life delays the onset of diabetes in the non-obese diabetic mouse
    • Chamson-Reig A, Arany EJ, Summers K, Hill DJ. A low protein diet in early life delays the onset of diabetes in the non-obese diabetic mouse. J Endocrinol 201: 231-239, 2009.
    • (2009) J Endocrinol , vol.201 , pp. 231-239
    • Chamson-Reig, A.1    Arany, E.J.2    Summers, K.3    Hill, D.J.4
  • 20
    • 33746094996 scopus 로고    scopus 로고
    • The intraovarian actions of estrogen receptor-alpha are necessary to repress the formation of morphological and functional Leydig-like cells in the female gonad
    • Couse JF, Yates MM, Rodriguez KF, Johnson JA, Poirier D, Korach KS. The intraovarian actions of estrogen receptor-alpha are necessary to repress the formation of morphological and functional Leydig-like cells in the female gonad. Endocrinology 147: 3666-3678, 2006.
    • (2006) Endocrinology , vol.147 , pp. 3666-3678
    • Couse, J.F.1    Yates, M.M.2    Rodriguez, K.F.3    Johnson, J.A.4    Poirier, D.5    Korach, K.S.6
  • 21
    • 84872389678 scopus 로고    scopus 로고
    • Protein Restriction during Early Life in Rats Alters Pancreatic GABAA Receptor Subunit Expression and Glucagon Secretion in Adulthood
    • Durst MA, Lux-Lantos VA, Hardy DB, Hill DJ, Arany EJ. Protein Restriction during Early Life in Rats Alters Pancreatic GABAA Receptor Subunit Expression and Glucagon Secretion in Adulthood. Can J Diabetes 36: 101-108, 2012.
    • (2012) Can J Diabetes , vol.36 , pp. 101-108
    • Durst, M.A.1    Lux-Lantos, V.A.2    Hardy, D.B.3    Hill, D.J.4    Arany, E.J.5
  • 23
    • 77952095735 scopus 로고    scopus 로고
    • Sex differences in glucose levels: A consequence of physiology or methodological convenience? The Inter99 study
    • Faerch K, Borch-Johnsen K, Vaag A, Jørgensen T, Witte DR. Sex differences in glucose levels: a consequence of physiology or methodological convenience? The Inter99 study. Diabetologia 53: 858-865, 2010.
    • (2010) Diabetologia , vol.53 , pp. 858-865
    • Faerch, K.1    Borch-Johnsen, K.2    Vaag, A.3    Jørgensen, T.4    Witte, D.R.5
  • 24
    • 46049110723 scopus 로고    scopus 로고
    • Modulation of cellular proliferation and differentiation through GABA(B) receptors expressed by undifferentiated neural progenitor cells isolated from fetal mouse brain
    • Fukui M, Nakamichi N, Yoneyama M, Ozawa S, Fujimori S, Takahata Y, Nakamura N, Taniura H, Yoneda Y. Modulation of cellular proliferation and differentiation through GABA(B) receptors expressed by undifferentiated neural progenitor cells isolated from fetal mouse brain. J Cell Physiol 216: 507-519, 2008.
    • (2008) J Cell Physiol , vol.216 , pp. 507-519
    • Fukui, M.1    Nakamichi, N.2    Yoneyama, M.3    Ozawa, S.4    Fujimori, S.5    Takahata, Y.6    Nakamura, N.7    Taniura, H.8    Yoneda, Y.9
  • 26
    • 0018721663 scopus 로고
    • Gamma-aminobutyric acid in peripheral tissue, with emphasis on the endocrine pancreas: Presence in two species and reduction by streptozotocin
    • Gerber JC 3rd, Hare TA. Gamma-aminobutyric acid in peripheral tissue, with emphasis on the endocrine pancreas: presence in two species and reduction by streptozotocin. Diabetes 28: 1073-1076, 1979.
    • (1979) Diabetes , vol.28 , pp. 1073-1076
    • Gerber III, J.C.1    Hare, T.A.2
  • 27
    • 0016888063 scopus 로고
    • Regulation of pancreatic insulin and glucagon secretion
    • Gerich JE, Charles MA, Grodsky GM. Regulation of pancreatic insulin and glucagon secretion. Annu Rev Physiol 38: 353-388, 1976.
    • (1976) Annu Rev Physiol , vol.38 , pp. 353-388
    • Gerich, J.E.1    Charles, M.A.2    Grodsky, G.M.3
  • 28
    • 25444532247 scopus 로고    scopus 로고
    • Profile of changes in gene expression in cultured hippocampal neurones evoked by the GABAB receptor agonist baclofen
    • Ghorbel MT, Becker KG, Henley JM. Profile of changes in gene expression in cultured hippocampal neurones evoked by the GABAB receptor agonist baclofen. Physiol Genomics 22: 93-98, 2005.
    • (2005) Physiol Genomics , vol.22 , pp. 93-98
    • Ghorbel, M.T.1    Becker, K.G.2    Henley, J.M.3
  • 29
    • 0025787665 scopus 로고
    • The influence of gamma-aminobutyric acid on hormone release by mouse and rat endocrine pancreas
    • Gilon P, Bertrand G, Loubatieres-Mariani MM, Remacle C, Henquin JC. The influence of gamma-aminobutyric acid on hormone release by mouse and rat endocrine pancreas. Endocrinology 129: 2521-2529, 1991.
    • (1991) Endocrinology , vol.129 , pp. 2521-2529
    • Gilon, P.1    Bertrand, G.2    Loubatieres-Mariani, M.M.3    Remacle, C.4    Henquin, J.C.5
  • 30
    • 0025895359 scopus 로고
    • Localization of GAD-like immunoreactivity in the pancreas and stomach of the rat and mouse
    • Gilon P, Tappaz M, Remacle C. Localization of GAD-like immunoreactivity in the pancreas and stomach of the rat and mouse. Histochemistry 96: 355-365, 1991.
    • (1991) Histochemistry , vol.96 , pp. 355-365
    • Gilon, P.1    Tappaz, M.2    Remacle, C.3
  • 31
    • 84871442771 scopus 로고    scopus 로고
    • Wired on sugar: The role of the CNS in the regulation of glucose homeostasis
    • Grayson BE, Seeley RJ, Sandoval DA. Wired on sugar: the role of the CNS in the regulation of glucose homeostasis. Nat Rev Neurosci 14: 24-37, 2012.
    • (2012) Nat Rev Neurosci , vol.14 , pp. 24-37
    • Grayson, B.E.1    Seeley, R.J.2    Sandoval, D.A.3
  • 32
    • 0028869514 scopus 로고
    • Expression of murine STF-1, a putative insulin gene transcription factor, in beta cells of pancreas, duodenal epithelium and pancreatic exocrine and endocrine progenitors during ontogeny
    • Guz Y, Montminy MR, Stein R, Leonard J, Gamer LW, Wright CV, Teitelman G. Expression of murine STF-1, a putative insulin gene transcription factor, in beta cells of pancreas, duodenal epithelium and pancreatic exocrine and endocrine progenitors during ontogeny. Development 121: 11-18, 1995.
    • (1995) Development , vol.121 , pp. 11-18
    • Guz, Y.1    Montminy, M.R.2    Stein, R.3    Leonard, J.4    Gamer, L.W.5    Wright, C.V.6    Teitelman, G.7
  • 33
    • 79961187526 scopus 로고    scopus 로고
    • Regulation of glucagon secretion by zinc: Lessons from the beta cellspecific Znt8 knockout mouse model
    • Hardy AB, Serino AS, Wijesekara N, Chimienti F, Wheeler MB. Regulation of glucagon secretion by zinc: lessons from the beta cellspecific Znt8 knockout mouse model. Diabetes Obes Metab 13, Suppl 1: 112-117, 2011.
    • (2011) Diabetes Obes Metab , vol.13 , Issue.SUPPL. 1 , pp. 112-117
    • Hardy, A.B.1    Serino, A.S.2    Wijesekara, N.3    Chimienti, F.4    Wheeler, M.B.5
  • 34
    • 18044396542 scopus 로고    scopus 로고
    • GABAB receptor antagonist SGS742 improves spatial memory and reduces protein binding to the cAMP response element (CRE) in the hippocampus
    • Helm KA, Haberman RP, Dean SL, Hoyt EC, Melcher T, Lund PK, Gallagher M. GABAB receptor antagonist SGS742 improves spatial memory and reduces protein binding to the cAMP response element (CRE) in the hippocampus. Neuropharmacology 48: 956-964, 2005.
    • (2005) Neuropharmacology , vol.48 , pp. 956-964
    • Helm, K.A.1    Haberman, R.P.2    Dean, S.L.3    Hoyt, E.C.4    Melcher, T.5    Lund, P.K.6    Gallagher, M.7
  • 35
    • 0035316084 scopus 로고    scopus 로고
    • Is pancreas development abnormal in the non-obese diabetic mouse, a spontaneous model of type I diabetes?
    • Homo-Delarche F. Is pancreas development abnormal in the non-obese diabetic mouse, a spontaneous model of type I diabetes? Braz J Med Biol Res 34: 437-447, 2001.
    • (2001) Braz J Med Biol Res , vol.34 , pp. 437-447
    • Homo-Delarche, F.1
  • 36
    • 2542450972 scopus 로고    scopus 로고
    • Low-protein diet during early life causes a reduction in the frequency of cells immunopositive for nestin and CD34 in both pancreatic ducts and islets in the rat
    • Joanette EA, Reusens B, Arany E, Thyssen S, Remacle RC, Hill DJ. Low-protein diet during early life causes a reduction in the frequency of cells immunopositive for nestin and CD34 in both pancreatic ducts and islets in the rat. Endocrinology 145: 3004-3013, 2004.
    • (2004) Endocrinology , vol.145 , pp. 3004-3013
    • Joanette, E.A.1    Reusens, B.2    Arany, E.3    Thyssen, S.4    Remacle, R.C.5    Hill, D.J.6
  • 37
    • 0028149890 scopus 로고
    • Insulin-promoter-factor 1 is required for pancreas development in mice
    • Jonsson J, Carlsson L, Edlund T, Edlund H. Insulin-promoter-factor 1 is required for pancreas development in mice. Nature 371: 606-609, 1994.
    • (1994) Nature , vol.371 , pp. 606-609
    • Jonsson, J.1    Carlsson, L.2    Edlund, T.3    Edlund, H.4
  • 38
    • 36248969612 scopus 로고    scopus 로고
    • Increased islet neogenesis without increased islet mass precedes autoimmune attack in diabetes-prone rats
    • Kauri LM, Wang GS, Patrick C, Bareggi M, Hill DJ, Scott FW. Increased islet neogenesis without increased islet mass precedes autoimmune attack in diabetes-prone rats. Lab Invest 87: 1240-1251, 2007.
    • (2007) Lab Invest , vol.87 , pp. 1240-1251
    • Kauri, L.M.1    Wang, G.S.2    Patrick, C.3    Bareggi, M.4    Hill, D.J.5    Scott, F.W.6
  • 39
    • 70450124317 scopus 로고    scopus 로고
    • Islet architecture: A comparative study
    • Kim A, Miller K, Jo J, Wojcik P, Hara M. Islet architecture: A comparative study. Islets 1: 129-136, 2009.
    • (2009) Islets , vol.1 , pp. 129-136
    • Kim, A.1    Miller, K.2    Jo, J.3    Wojcik, P.4    Hara, M.5
  • 41
    • 77952884832 scopus 로고    scopus 로고
    • Reprogramming into pancreatic endocrine cells based on developmental cues
    • Kordowich S, Mansouri A, Collombat P. Reprogramming into pancreatic endocrine cells based on developmental cues. Mol Cell Endocrinol 323: 62-69, 2010.
    • (2010) Mol Cell Endocrinol , vol.323 , pp. 62-69
    • Kordowich, S.1    Mansouri, A.2    Collombat, P.3
  • 42
    • 0027373441 scopus 로고
    • Characterization of somatostatin transactivating factor-1, a novel homeobox factor that stimulates somatostatin expression in pancreatic islet cells
    • Leonard J, Peers B, Johnson T, Ferreri K, Lee S, Montminy MR. Characterization of somatostatin transactivating factor-1, a novel homeobox factor that stimulates somatostatin expression in pancreatic islet cells. Mol Endocrinol 7: 1275-1283, 1993.
    • (1993) Mol Endocrinol , vol.7 , pp. 1275-1283
    • Leonard, J.1    Peers, B.2    Johnson, T.3    Ferreri, K.4    Lee, S.5    Montminy, M.R.6
  • 44
    • 33847686231 scopus 로고    scopus 로고
    • Regulation of pancreatic islet cell survival and replication by gamma-aminobutyric acid
    • Ligon B, Yang J, Morin SB, Ruberti MF, Steer ML. Regulation of pancreatic islet cell survival and replication by gamma-aminobutyric acid. Diabetologia 50: 764-773, 2007.
    • (2007) Diabetologia , vol.50 , pp. 764-773
    • Ligon, B.1    Yang, J.2    Morin, S.B.3    Ruberti, M.F.4    Steer, M.L.5
  • 46
    • 77956282569 scopus 로고    scopus 로고
    • The role of the KATP channel in glucose homeostasis in health and disease: More than meets the islet
    • McTaggart JS, Clark RH, Ashcroft FM. The role of the KATP channel in glucose homeostasis in health and disease: more than meets the islet. J Physiol 588: 3201-3209, 2010.
    • (2010) J Physiol , vol.588 , pp. 3201-3209
    • McTaggart, J.S.1    Clark, R.H.2    Ashcroft, F.M.3
  • 47
    • 80051668223 scopus 로고    scopus 로고
    • Obesity, insulin resistance and diabetes: Sex differences and role of oestrogen receptors
    • Meyer MR, Clegg DJ, Prossnitz ER, Barton M. Obesity, insulin resistance and diabetes: sex differences and role of oestrogen receptors. Acta Physiol (Oxf) 203: 259-269, 2011.
    • (2011) Acta Physiol (Oxf) , vol.203 , pp. 259-269
    • Meyer, M.R.1    Clegg, D.J.2    Prossnitz, E.R.3    Barton, M.4
  • 48
    • 67649646380 scopus 로고    scopus 로고
    • Neurogenesis mediated by gamma-aminobutyric acid and glutamate signaling
    • Nakamichi N, Takarada T, Yoneda Y. Neurogenesis mediated by gamma-aminobutyric acid and glutamate signaling. J Pharmacol Sci 110: 133-149, 2009.
    • (2009) J Pharmacol Sci , vol.110 , pp. 133-149
    • Nakamichi, N.1    Takarada, T.2    Yoneda, Y.3
  • 49
    • 77649171913 scopus 로고    scopus 로고
    • Changes in islet microvasculature following streptozotocin-induced beta-cell loss and subsequent replacement in the neonatal rat
    • Nicholson JM, Arany EJ, Hill DJ. Changes in islet microvasculature following streptozotocin-induced beta-cell loss and subsequent replacement in the neonatal rat. Exp Biol Med (Maywood) 235: 189-198, 2010.
    • (2010) Exp Biol Med (Maywood) , vol.235 , pp. 189-198
    • Nicholson, J.M.1    Arany, E.J.2    Hill, D.J.3
  • 51
    • 17344392308 scopus 로고    scopus 로고
    • A new mathematical model for relative quantification in real-time RT-PCR
    • Pfaffl MW. A new mathematical model for relative quantification in real-time RT-PCR. Nucleic Acids Res 29: e45, 2001.
    • (2001) Nucleic Acids Res , vol.29
    • Pfaffl, M.W.1
  • 52
    • 0031557654 scopus 로고    scopus 로고
    • Ontogeny of glutamic acid decarboxylase gene expression in the mouse pancreas
    • Pleau JM, Throsby M, Esling A, Dardenne M. Ontogeny of glutamic acid decarboxylase gene expression in the mouse pancreas. Biochem Biophys Res Commun 233: 227-230, 1997.
    • (1997) Biochem Biophys Res Commun , vol.233 , pp. 227-230
    • Pleau, J.M.1    Throsby, M.2    Esling, A.3    Dardenne, M.4
  • 53
    • 77949878205 scopus 로고    scopus 로고
    • Cellular plasticity within the pancreas-lessons learned from development
    • Puri S, Hebrok M. Cellular plasticity within the pancreas-lessons learned from development. Dev Cell 18: 342-356, 2010.
    • (2010) Dev Cell , vol.18 , pp. 342-356
    • Puri, S.1    Hebrok, M.2
  • 54
    • 0019402937 scopus 로고
    • Effect of muscimol on glucose-stimulated somatostatin and insulin release from the isolated, perfused rat pancreas
    • Robbins MS, Grouse LH, Sorenson RL, Elde RP. Effect of muscimol on glucose-stimulated somatostatin and insulin release from the isolated, perfused rat pancreas. Diabetes 30: 168-171, 1981.
    • (1981) Diabetes , vol.30 , pp. 168-171
    • Robbins, M.S.1    Grouse, L.H.2    Sorenson, R.L.3    Elde, R.P.4
  • 55
    • 79961205866 scopus 로고    scopus 로고
    • A role for zinc in pancreatic islet beta-cell cross-talk with the alpha-cell during hypoglycaemia
    • Robertson RP, Zhou H, Slucca M. A role for zinc in pancreatic islet beta-cell cross-talk with the alpha-cell during hypoglycaemia. Diabetes Obes Metab 13, Suppl 1: 106-111, 2011.
    • (2011) Diabetes Obes Metab , vol.13 , Issue.SUPPL. 1 , pp. 106-111
    • Robertson, R.P.1    Zhou, H.2    Slucca, M.3
  • 57
    • 84858288206 scopus 로고    scopus 로고
    • Regulation of calcium in pancreatic alpha-and beta-cells in health and disease
    • Rorsman P, Braun M, Zhang Q. Regulation of calcium in pancreatic alpha-and beta-cells in health and disease. Cell Calcium 51: 300-3008, 2012.
    • (2012) Cell Calcium , vol.51 , pp. 300-3008
    • Rorsman, P.1    Braun, M.2    Zhang, Q.3
  • 58
    • 76249094159 scopus 로고    scopus 로고
    • Isolation and characterization of centroacinar/terminal ductal progenitor cells in adult mouse pancreas
    • Rovira M, Scott SG, Liss AS, Jensen J, Thayer SP, Leach SD. Isolation and characterization of centroacinar/terminal ductal progenitor cells in adult mouse pancreas. Proc Natl Acad Sci USA 107: 75-80, 2010.
    • (2010) Proc Natl Acad Sci USA , vol.107 , pp. 75-80
    • Rovira, M.1    Scott, S.G.2    Liss, A.S.3    Jensen, J.4    Thayer, S.P.5    Leach, S.D.6
  • 59
  • 64
    • 0025945011 scopus 로고
    • Structural and functional considerations of GABA in islets of Langerhans. Beta-cells and nerves
    • Sorenson RL, Garry DG, Brelje TC. Structural and functional considerations of GABA in islets of Langerhans. Beta-cells and nerves. Diabetes 40: 1365-1374, 1991.
    • (1991) Diabetes , vol.40 , pp. 1365-1374
    • Sorenson, R.L.1    Garry, D.G.2    Brelje, T.C.3
  • 66
    • 80053085802 scopus 로고    scopus 로고
    • Combining antigen-based therapy with GABA treatment synergistically prolongs survival of transplanted ss-cells in diabetic NOD mice
    • Tian J, Dang H, Kaufman DL. Combining antigen-based therapy with GABA treatment synergistically prolongs survival of transplanted ss-cells in diabetic NOD mice. PLoS One 6: e25337, 2011.
    • (2011) PLoS One , vol.6
    • Tian, J.1    Dang, H.2    Kaufman, D.L.3
  • 67
    • 12144283149 scopus 로고    scopus 로고
    • Comparison of cellular and medium insulin and GABA content as markers for living β-cells
    • Wang C, Ling Z, Pipeleers D. Comparison of cellular and medium insulin and GABA content as markers for living β-cells. Am J Physiol Endocrinol Metab 288: E307-E313, 2005.
    • (2005) Am J Physiol Endocrinol Metab , vol.288
    • Wang, C.1    Ling, Z.2    Pipeleers, D.3
  • 68
    • 84862804393 scopus 로고    scopus 로고
    • Reversible immortalization of Nestin-positive precursor cells from pancreas and differentiation into insulin-secreting cells
    • Wei P, Li L, Qi H, Zhou HX, Deng CY, Li FR. Reversible immortalization of Nestin-positive precursor cells from pancreas and differentiation into insulin-secreting cells. Biochem Biophys Res Commun 418: 330-335, 2012.
    • (2012) Biochem Biophys Res Commun , vol.418 , pp. 330-335
    • Wei, P.1    Li, L.2    Qi, H.3    Zhou, H.X.4    Deng, C.Y.5    Li, F.R.6
  • 69
    • 1842422955 scopus 로고    scopus 로고
    • Glucose inhibition of glucagon secretion from rat alpha-cells is mediated by GABA released from neighboring beta-cells
    • Wendt A, Birnir B, Buschard K, Gromada J, Salehi A, Sewing S, Rorsman P, Braun M. Glucose inhibition of glucagon secretion from rat alpha-cells is mediated by GABA released from neighboring beta-cells. Diabetes 53: 1038-1045, 2004.
    • (2004) Diabetes , vol.53 , pp. 1038-1045
    • Wendt, A.1    Birnir, B.2    Buschard, K.3    Gromada, J.4    Salehi, A.5    Sewing, S.6    Rorsman, P.7    Braun, M.8
  • 73
    • 84863039246 scopus 로고    scopus 로고
    • Insulin-producing cells are bi-potential and differentiatorsprior to proliferation in early human development
    • Yang KM, Yong W, Li AD, Yang HJ. Insulin-producing cells are bi-potential and differentiatorsprior to proliferation in early human development. World J Diabetes 2: 54-58, 2011.
    • (2011) World J Diabetes , vol.2 , pp. 54-58
    • Yang, K.M.1    Yong, W.2    Li, A.D.3    Yang, H.J.4
  • 74
    • 0035119871 scopus 로고    scopus 로고
    • Multipotential nestin-positive stem cells isolated from adult pancreatic islets differentiate ex vivo into pancreatic endocrine, exocrine, and hepatic phenotypes
    • Zulewski H, Abraham EJ, Gerlach MJ, Daniel PB, Moritz W, Muller B, Vallejo M, Thomas MK, Habener JF. Multipotential nestin-positive stem cells isolated from adult pancreatic islets differentiate ex vivo into pancreatic endocrine, exocrine, and hepatic phenotypes. Diabetes 50: 521-533, 2001.
    • (2001) Diabetes , vol.50 , pp. 521-533
    • Zulewski, H.1    Abraham, E.J.2    Gerlach, M.J.3    Daniel, P.B.4    Moritz, W.5    Muller, B.6    Vallejo, M.7    Thomas, M.K.8    Habener, J.F.9


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.