Pasteurella Multocida Toxin Prevents Osteoblast Differentiation by Transactivation of the MAP-Kinase Cascade via the Gαq/11 - p63RhoGEF - RhoA Axis

PLoS Pathogens

Volumn 9, Issue 5, 2013, Pages

  Siegert, Peter ^a,b   Schmidt, Gudula ^a   Papatheodorou, Panagiotis ^a   Wieland, Thomas ^c   Aktories, Klaus ^a,b   Orth, Joachim H C ^a  

^a UNIVERSITY OF FREIBURG   (Germany)

^b UNIVERSITY OF FREIBURG   (Germany)

^c UNIVERSITY OF HEIDELBERG   (Germany)

Author keywords

[No Author keywords available]

Indexed keywords

ALKALINE PHOSPHATASE; BACTERIAL TOXIN; CCAAT ENHANCER BINDING PROTEIN; GLUTAMINE; GUANINE NUCLEOTIDE BINDING PROTEIN; MESSENGER RNA; MITOGEN ACTIVATED PROTEIN KINASE; MITOGEN ACTIVATED PROTEIN KINASE KINASE 1; PEROXISOME PROLIFERATOR ACTIVATED RECEPTOR GAMMA; PROTEIN TYROSINE KINASE; RHO KINASE; RHOA GUANINE NUCLEOTIDE BINDING PROTEIN; TRANSCRIPTION FACTOR OSTERIX; VIRULENCE FACTOR;

ADIPOCYTE; ADIPOGENESIS; ANIMAL CELL; ARTICLE; ATROPHIC RHINITIS; BONE DESTRUCTION; BONE MINERALIZATION; CONTROLLED STUDY; GENE EXPRESSION; IMMUNOBLOTTING; MOUSE; NONHUMAN; OSTEOBLAST; OSTEOCLAST; OSTEOLYSIS; PASTEURELLA MULTOCIDA; PHOSPHORYLATION; POLYACRYLAMIDE GEL ELECTROPHORESIS; POLYMERASE CHAIN REACTION; RAT; RNA EXTRACTION; STAINING; STROMA CELL; TISSUE DIFFERENTIATION; TRANSACTIVATION; TURBINATE;

ANIMALS; BACTERIAL PROTEINS; BACTERIAL TOXINS; CELL DIFFERENTIATION; CELL LINE; GTP-BINDING PROTEIN ALPHA SUBUNITS, GQ-G11; MAP KINASE SIGNALING SYSTEM; MICE; OSTEOBLASTS; OSTEOLYSIS; PASTEURELLA INFECTIONS; PASTEURELLA MULTOCIDA; RATS; RHINITIS, ATROPHIC; RHO GTP-BINDING PROTEINS; RHO GUANINE NUCLEOTIDE EXCHANGE FACTORS; SKULL; STROMAL CELLS; TRANSCRIPTIONAL ACTIVATION; VIRULENCE FACTORS;

ANIMALIA; BACTERIA (MICROORGANISMS); PASTEURELLA MULTOCIDA; RATTUS;

EID: 84878505226     PISSN: 15537366     EISSN: 15537374     Source Type: Journal    
DOI: 10.1371/journal.ppat.1003385     Document Type: Article

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