-
1
-
-
0038688357
-
The genetic basis for skeletal diseases
-
DOI 10.1038/nature01659
-
Zelzer E, Olsen BR. The genetic basis for skeletal diseases. Nature. 2003;423(6937):343-348. (Pubitemid 40852709)
-
(2003)
Nature
, vol.423
, Issue.6937
, pp. 343-348
-
-
Zelzer, E.1
Olsen, B.R.2
-
2
-
-
34447132814
-
Skeletal remodeling in health and disease
-
DOI 10.1038/nm1593, PII NM1593
-
Zaidi M. Skeletal remodeling in health and disease. Nat Med. 2007;13(7):791-801. (Pubitemid 47038187)
-
(2007)
Nature Medicine
, vol.13
, Issue.7
, pp. 791-801
-
-
Zaidi, M.1
-
3
-
-
0036225281
-
Reaching a genetic and molecular understanding of skeletal development
-
DOI 10.1016/S1534-5807(02)00157-0
-
Karsenty G, Wagner EF. Reaching a genetic and molecular understanding of skeletal development. Dev Cell. 2002;2(4):389-406. (Pubitemid 34436569)
-
(2002)
Developmental Cell
, vol.2
, Issue.4
, pp. 389-406
-
-
Karsenty, G.1
Wagner, E.F.2
-
4
-
-
75049085147
-
Osteoimmunology and the effects of the immune system on bone
-
Takayanagi H. Osteoimmunology and the effects of the immune system on bone. Nat Rev Rheumatol. 2009;5(12):667-676.
-
(2009)
Nat Rev Rheumatol
, vol.5
, Issue.12
, pp. 667-676
-
-
Takayanagi, H.1
-
5
-
-
79959974072
-
TRANCE, a new tumor necrosis factor (TNF) family member predominantly expressed in T cells, is a dendritic cell-specific survival factor
-
Wong BR, et al. TRANCE, a new tumor necrosis factor (TNF) family member predominantly expressed in T cells, is a dendritic cell-specific survival factor. J Exp Med. 1997;186(1):1-6.
-
(1997)
J Exp Med
, vol.186
, Issue.1
, pp. 1-6
-
-
Wong, B.R.1
-
6
-
-
14444272043
-
TRANCE is a novel ligand of the tumor necrosis factor receptor family that activates c-Jun N-terminal kinase in T cells
-
DOI 10.1074/jbc.272.40.25190
-
Wong BR, et al. TRANCE is a novel ligand of the tumor necrosis factor receptor family that activates c-Jun N-terminal kinase in T cells. J Biol Chem. 1997;272(40):25190-25194. (Pubitemid 27415705)
-
(1997)
Journal of Biological Chemistry
, vol.272
, Issue.40
, pp. 25190-25194
-
-
Wong, B.R.1
Rho, J.2
Arron, J.3
Robinson, E.4
Orlinick, J.5
Chao, M.6
Kalachikov, S.7
Cayani, E.8
Bartlett III, F.S.9
Frankel, W.N.10
Lee, S.Y.11
Choi, Y.12
-
7
-
-
0033611467
-
OPGL is a key regulator of osteoclastogenesis, lymphocyte development and lymph-node organogenesis
-
Kong YY, et al. OPGL is a key regulator of osteoclastogenesis, lymphocyte development and lymph-node organogenesis. Nature. 1999;397(6717):315-323.
-
(1999)
Nature
, vol.397
, Issue.6717
, pp. 315-323
-
-
Kong, Y.Y.1
-
8
-
-
0034718609
-
Diverse roles of the tumor necrosis factor family member TRANCE in skeletal physiology revealed by TRANCE deficiency and partial rescue by a lymphocyte-expressed TRANCE transgene
-
Kim N, Odgren PR, Kim DK, Marks SC Jr, Choi Y. Diverse roles of the tumor necrosis factor family member TRANCE in skeletal physiology revealed by TRANCE deficiency and partial rescue by a lymphocyte-expressed TRANCE transgene. Proc Natl Acad Sci U S A. 2000;97(20):10905-10910.
-
(2000)
Proc Natl Acad Sci U S A
, vol.97
, Issue.20
, pp. 10905-10910
-
-
Kim, N.1
Odgren, P.R.2
Kim, D.K.3
Marks Jr., S.C.4
Choi, Y.5
-
9
-
-
58149308297
-
Infantile malignant, autosomal recessive osteopetrosis: The rich and the poor
-
Villa A, Guerrini MM, Cassani B, Pangrazio A, Sobacchi C. Infantile malignant, autosomal recessive osteopetrosis: the rich and the poor. Calcif Tissue Int. 2009;84(1):1-12.
-
(2009)
Calcif Tissue Int
, vol.84
, Issue.1
, pp. 1-12
-
-
Villa, A.1
Guerrini, M.M.2
Cassani, B.3
Pangrazio, A.4
Sobacchi, C.5
-
10
-
-
27744432009
-
Autoamplification of NFATc1 expression determines its essential role in bone homeostasis
-
DOI 10.1084/jem.20051150
-
Asagiri M, et al. Autoamplification of NFATc1 expression determines its essential role in bone homeostasis. J Exp Med. 2005;202(9):1261-1269. (Pubitemid 41586956)
-
(2005)
Journal of Experimental Medicine
, vol.202
, Issue.9
, pp. 1261-1269
-
-
Asagiri, M.1
Sato, K.2
Usami, T.3
Ochi, S.4
Nishina, H.5
Yoshida, H.6
Morita, I.7
Wagner, E.F.8
Mak, T.W.9
Serfling, E.10
Takayanagi, H.11
-
11
-
-
55849088412
-
NFATc1 in mice represses osteoprotegerin during osteoclastogenesis and dissociates systemic osteopenia from inflammation in cherubism
-
Aliprantis AO, et al. NFATc1 in mice represses osteoprotegerin during osteoclastogenesis and dissociates systemic osteopenia from inflammation in cherubism. J Clin Invest. 2008;118(11):3775-3789.
-
(2008)
J Clin Invest
, vol.118
, Issue.11
, pp. 3775-3789
-
-
Aliprantis, A.O.1
-
12
-
-
18744366041
-
Induction and activation of the transcription factor NFATc1 (NFAT2) integrate RANKL signaling in terminal differentiation of osteoclasts
-
DOI 10.1016/S1534-5807(02)00369-6
-
Takayanagi H, et al. Induction and activation of the transcription factor NFATc1 (NFAT2) integrate RANKL signaling in terminal differentiation of osteoclasts. Dev Cell. 2002;3(6):889-901. (Pubitemid 35460788)
-
(2002)
Developmental Cell
, vol.3
, Issue.6
, pp. 889-901
-
-
Takayanagi, H.1
Kim, S.2
Koga, T.3
Nishina, H.4
Isshiki, M.5
Yoshida, H.6
Saiura, A.7
Isobe, M.8
Yokochi, T.9
Inoue, J.-I.10
Wagner, E.F.11
Mak, T.W.12
Kodama, T.13
Taniguchi, T.14
-
13
-
-
70349100754
-
Ca2+-NFATc1 signaling is an essential axis of osteoclast differentiation
-
Negishi-Koga T, Takayanagi H. Ca2+-NFATc1 signaling is an essential axis of osteoclast differentiation. Immunol Rev. 2009;231(1):241-256.
-
(2009)
Immunol Rev
, vol.231
, Issue.1
, pp. 241-256
-
-
Negishi-Koga, T.1
Takayanagi, H.2
-
14
-
-
77953151846
-
Novel functions of RANK(L) signaling in the immune system
-
Leibbrandt A, Penninger JM. Novel functions of RANK(L) signaling in the immune system. Adv Exp Med Biol. 2010;658:77-94.
-
(2010)
Adv Exp Med Biol
, vol.658
, pp. 77-94
-
-
Leibbrandt, A.1
Penninger, J.M.2
-
16
-
-
47249086030
-
The role and therapeutic implications of fibroblast-like synoviocytes in inflammation and cartilage erosion in rheumatoid arthritis
-
DOI 10.1111/j.1600-065X.2008.00648.x
-
Noss EH, Brenner MB. The role and therapeutic implications of fibroblast-like synoviocytes in inflammation and cartilage erosion in rheumatoid arthritis. Immunol Rev. 2008;223:252-270. (Pubitemid 351986192)
-
(2008)
Immunological Reviews
, vol.223
, Issue.1
, pp. 252-270
-
-
Noss, E.H.1
Brenner, M.B.2
-
17
-
-
33846781303
-
Outcomes in rheumatoid arthritis: Incorporating the patient perspective
-
DOI 10.1097/BOR.0b013e32802bf79d, PII 0000228120070300000004
-
Heller JE, Shadick NA. Outcomes in rheumatoid arthritis: incorporating the patient perspective. Curr Opin Rheumatol. 2007;19(2):101-105. (Pubitemid 46208765)
-
(2007)
Current Opinion in Rheumatology
, vol.19
, Issue.2
, pp. 101-105
-
-
Heller, J.E.1
Shadick, N.A.2
-
18
-
-
70349140060
-
Biologics for rheumatoid arthritis: An overview of Cochrane reviews
-
CD007848
-
Singh JA, et al. Biologics for rheumatoid arthritis: an overview of Cochrane reviews. Cochrane Database Syst Rev. 2009;(4):CD007848.
-
(2009)
Cochrane Database Syst Rev
, Issue.4
-
-
Singh, J.A.1
-
20
-
-
77953261340
-
Bone damage in rheumatoid arthritis: Mechanistic insights and approaches to prevention
-
Karmakar S, Kay J, Gravallese EM. Bone damage in rheumatoid arthritis: mechanistic insights and approaches to prevention. Rheum Dis Clin North Am. 2010;36(2):385-404.
-
(2010)
Rheum Dis Clin North Am
, vol.36
, Issue.2
, pp. 385-404
-
-
Karmakar, S.1
Kay, J.2
Gravallese, E.M.3
-
21
-
-
0035153246
-
TRANCE/RANKL knockout mice are protected from bone erosion in a serum transfer model of arthritis
-
Pettit AR, et al. TRANCE/RANKL knockout mice are protected from bone erosion in a serum transfer model of arthritis. Am J Pathol. 2001; 159(5):1689-1699. (Pubitemid 33062512)
-
(2001)
American Journal of Pathology
, vol.159
, Issue.5
, pp. 1689-1699
-
-
Pettit, A.R.1
Ji, H.2
Von Stechow, D.3
Muller, R.4
Goldring, S.R.5
Choi, Y.6
Benoist, C.7
Gravallese, E.M.8
-
22
-
-
0036853902
-
Osteoclasts are essential for TNF-α-mediated joint destruction
-
DOI 10.1172/JCI200215582
-
Redlich K, et al. Osteoclasts are essential for TNFα-mediated joint destruction. J Clin Invest. 2002;110(10):1419-1427. (Pubitemid 35396913)
-
(2002)
Journal of Clinical Investigation
, vol.110
, Issue.10
, pp. 1419-1427
-
-
Redlich, K.1
Hayer, S.2
Ricci, R.3
David, J.-P.4
Tohidast-Akrad, M.5
Kollias, G.6
Steiner, G.7
Smolen, J.S.8
Wagner, E.F.9
Schett, G.10
-
23
-
-
0033581952
-
Activated T cells regulate bone loss and joint destruction in adjuvant arthritis through osteoprotegerin ligand
-
Kong YY, et al. Activated T cells regulate bone loss and joint destruction in adjuvant arthritis through osteoprotegerin ligand. Nature. 1999;402(6759):304-309.
-
(1999)
Nature
, vol.402
, Issue.6759
, pp. 304-309
-
-
Kong, Y.Y.1
-
24
-
-
3142763806
-
Targeting osteoclasts with zoledronic acid prevents bone destruction in collagen-induced arthritis
-
DOI 10.1002/art.20382
-
Sims NA, et al. Targeting osteoclasts with zoledronic acid prevents bone destruction in collagen-induced arthritis. Arthritis Rheum. 2004;50(7):2338- 2346. (Pubitemid 38924414)
-
(2004)
Arthritis and Rheumatism
, vol.50
, Issue.7
, pp. 2338-2346
-
-
Sims, N.A.1
Green, J.R.2
Glatt, M.3
Schlict, S.4
Martin, T.J.5
Gillespie, M.T.6
Romas, E.7
-
25
-
-
3142741595
-
Zoledronic acid protects against local and systemic bone loss in tumor necrosis factor-mediated arthritis
-
DOI 10.1002/art.20384
-
Herrak P, et al. Zoledronic acid protects against local and systemic bone loss in tumor necrosis factor-mediated arthritis. Arthritis Rheum. 2004;50(7):2327-2337. (Pubitemid 38924413)
-
(2004)
Arthritis and Rheumatism
, vol.50
, Issue.7
, pp. 2327-2337
-
-
Herrak, P.1
Gortz, B.2
Hayer, S.3
Redlich, K.4
Reiter, E.5
Gasser, J.6
Bergmeister, H.7
Kollias, G.8
Smolen, J.S.9
Schett, G.10
-
26
-
-
33646484359
-
Preliminary evidence for a structural benefit of the new bisphosphonate zoledronic acid in early rheumatoid arthritis
-
Jarrett SJ, et al. Preliminary evidence for a structural benefit of the new bisphosphonate zoledronic acid in early rheumatoid arthritis. Arthritis Rheum. 2006;54(5):1410-1414.
-
(2006)
Arthritis Rheum
, vol.54
, Issue.5
, pp. 1410-1414
-
-
Jarrett, S.J.1
-
27
-
-
43949139580
-
Denosumab treatment effects on structural damage, bone mineral density, and bone turnover in rheumatoid arthritis: A twelve-month, multicenter, randomized, double-blind, placebo-controlled, phase II clinical trial
-
DOI 10.1002/art.23417
-
Cohen SB, et al. Denosumab treatment effects on structural damage, bone mineral density, and bone turnover in rheumatoid arthritis: a twelve-month, multicenter, randomized, double-blind, placebo-controlled, phase II clinical trial. Arthritis Rheum. 2008;58(5):1299-1309. (Pubitemid 351705919)
-
(2008)
Arthritis and Rheumatism
, vol.58
, Issue.5
, pp. 1299-1309
-
-
Cohen, S.B.1
Dore, R.K.2
Lane, N.E.3
Ory, P.A.4
Peterfy, C.G.5
Sharp, J.T.6
Van Der, H.D.7
Zhou, L.8
Tsuji, W.9
Newmark, R.10
-
28
-
-
60549110257
-
Immune regulation of bone loss by Th17 cells
-
Adamopoulos IE, Bowman EP. Immune regulation of bone loss by Th17 cells. Arthritis Res Ther. 2008;10(5):225.
-
(2008)
Arthritis Res Ther
, vol.10
, Issue.5
, pp. 225
-
-
Adamopoulos, I.E.1
Bowman, E.P.2
-
29
-
-
0033547343
-
Activated T lymphocytes support osteoclast formation in vitro
-
Horwood NJ, Kartsogiannis V, Quinn JM, Romas E, Martin TJ, Gillespie MT. Activated T lymphocytes support osteoclast formation in vitro. Biochem Biophys Res Commun. 1999;265(1):144-150.
-
(1999)
Biochem Biophys Res Commun
, vol.265
, Issue.1
, pp. 144-150
-
-
Horwood, N.J.1
Kartsogiannis, V.2
Quinn, J.M.3
Romas, E.4
Martin, T.J.5
Gillespie, M.T.6
-
30
-
-
17444452820
-
Activated human T cells directly induce osteoclastogenesis from human monocytes: Possible role of T cells in bone destruction in rheumatoid arthritis patients
-
DOI 10.1002/1529-0131(200105)44:5<1003::AID-ANR179>3.0.CO;2-#
-
Kotake S, et al. Activated human T cells directly induce osteoclastogenesis from human monocytes: possible role of T cells in bone destruction in rheumatoid arthritis patients. Arthritis Rheum. 2001;44(5):1003-1012. (Pubitemid 32433604)
-
(2001)
Arthritis and Rheumatism
, vol.44
, Issue.5
, pp. 1003-1012
-
-
Kotake, S.1
Udagawa, N.2
Hakoda, M.3
Mogi, M.4
Yano, K.5
Tsuda, E.6
Takahashi, K.7
Furuya, T.8
Ishiyama, S.9
Kim, K.-J.10
Saito, S.11
Nishikawa, T.12
Takahashi, N.13
Togari, A.14
Tomatsu, T.15
Suda, T.16
Kamatani, N.17
-
31
-
-
0034735773
-
T-cell-mediated regulation of osteoclastogenesis by signalling cross-talk between RANKL and IFN-γ
-
Takayanagi H, et al. T-cell-mediated regulation of osteoclastogenesis by signalling cross-talk between RANKL and IFN-γ. Nature. 2000;408(6812):600-605.
-
(2000)
Nature
, vol.408
, Issue.6812
, pp. 600-605
-
-
Takayanagi, H.1
-
32
-
-
27944457190
-
IFN-γ-producing human T cells directly induce osteoclastogenesis from human monocytes via the expression of RANKL
-
DOI 10.1002/eji.200526141
-
Kotake S, et al. IFN-γ-producing human T cells directly induce osteoclastogenesis from human monocytes via the expression of RANKL. Eur J Immunol. 2005;35(11):3353-3363. (Pubitemid 41672539)
-
(2005)
European Journal of Immunology
, vol.35
, Issue.11
, pp. 3353-3363
-
-
Kotake, S.1
Nanke, Y.2
Mogi, M.3
Kawamoto, M.4
Furuya, T.5
Yago, T.6
Kobashigawa, T.7
Togari, A.8
Kamatani, N.9
-
33
-
-
33845981069
-
IFN-γ stimulates osteoclast formation and bone loss in vivo via antigen-driven T cell activation
-
DOI 10.1172/JCI30074
-
Gao Y, et al. IFN-γ stimulates osteoclast formation and bone loss in vivo via antigen-driven T cell activation. J Clin Invest. 2007;117(1):122-132. (Pubitemid 46048459)
-
(2007)
Journal of Clinical Investigation
, vol.117
, Issue.1
, pp. 122-132
-
-
Gao, Y.1
Grassi, F.2
Ryan, M.R.3
Terauchi, M.4
Page, K.5
Yang, X.6
Weitzmann, M.N.7
Pacifici, R.8
-
34
-
-
0033134608
-
IL-17 in synovial fluids from patients with rheumatoid arthritis is a potent stimulator of osteoclastogenesis
-
Kotake S, et al. IL-17 in synovial fluids from patients with rheumatoid arthritis is a potent stimulator of osteoclastogenesis. J Clin Invest. 1999;103(9):1345-1352. (Pubitemid 29218305)
-
(1999)
Journal of Clinical Investigation
, vol.103
, Issue.9
, pp. 1345-1352
-
-
Kotake, S.1
Udagawa, N.2
Takahashi, N.3
Matsuzaki, K.4
Itoh, K.5
Ishiyama, S.6
Saito, S.7
Inoue, K.8
Kamatani, N.9
Gillespie, M.T.10
Martin, T.J.11
Suda, T.12
-
35
-
-
33751521013
-
Th17 functions as an osteoclastogenic helper T cell subset that links T cell activation and bone destruction
-
DOI 10.1084/jem.20061775
-
Sato K, et al. Th17 functions as an osteoclastogenic helper T cell subset that links T cell activation and bone destruction. J Exp Med. 2006;203(12):2673-2682. (Pubitemid 44833343)
-
(2006)
Journal of Experimental Medicine
, vol.203
, Issue.12
, pp. 2673-2682
-
-
Sato, K.1
Suematsu, A.2
Okamoto, K.3
Yamaguchi, A.4
Morishita, Y.5
Kadono, Y.6
Tanaka, S.7
Kodama, T.8
Akira, S.9
Iwakura, Y.10
Cua, D.J.11
Takayanagi, H.12
-
36
-
-
77958072084
-
Effects of AIN457, a fully human antibody to interleukin-17A, on psoriasis, rheumatoid arthritis, and uveitis
-
Hueber W, et al. Effects of AIN457, a fully human antibody to interleukin-17A, on psoriasis, rheumatoid arthritis, and uveitis. Sci Transl Med. 2010;2(52):52ra72.
-
(2010)
Sci Transl Med
, vol.2
, Issue.52
-
-
Hueber, W.1
-
37
-
-
77950535421
-
LY2439821, a humanized anti-interleukin-17 monoclonal antibody, in the treatment of patients with rheumatoid arthritis: A phase I randomized, double-blind, placebo-controlled, proof-of-concept study
-
Genovese MC, et al. LY2439821, a humanized anti-interleukin-17 monoclonal antibody, in the treatment of patients with rheumatoid arthritis: A phase I randomized, double-blind, placebo-controlled, proof-of-concept study. Arthritis Rheum. 2010;62(4):929-939.
-
(2010)
Arthritis Rheum
, vol.62
, Issue.4
, pp. 929-939
-
-
Genovese, M.C.1
-
38
-
-
60649092609
-
New biologics for psoriasis and psoriatic arthritis
-
Rozenblit M, Lebwohl M. New biologics for psoriasis and psoriatic arthritis. Dermatol Ther. 2009;22(1):56-60.
-
(2009)
Dermatol Ther
, vol.22
, Issue.1
, pp. 56-60
-
-
Rozenblit, M.1
Lebwohl, M.2
-
39
-
-
0034121039
-
Involvement of receptor activator of nuclear factor κB ligand/osteoclast differentiation factor in osteoclastogenesis from synoviocytes in rheumatoid arthritis
-
DOI 10.1002/1529-0131(200002)43:2<259::AID-ANR4>3.0.CO;2-W
-
Takayanagi H, et al. Involvement of receptor activator of nuclear factor-κB ligand/osteoclast differentiation factor in osteoclastogenesis from synoviocytes in rheumatoid arthritis. Arthritis Rheum. 2000;43(2):259-269. (Pubitemid 30395733)
-
(2000)
Arthritis and Rheumatism
, vol.43
, Issue.2
, pp. 259-269
-
-
Takayanagi, H.1
Iizuka, H.2
Juji, T.3
Nakagawa, T.4
Yamamoto, A.5
Miyazaki, T.6
Koshihara, Y.7
Oda, H.8
Nakamura, K.9
Tanaka, S.10
-
40
-
-
0031576524
-
A new mechanism of bone destruction in rheumatoid arthritis: Synovial fibroblasts induce osteoclastogenesis
-
DOI 10.1006/bbrc.1997.7404
-
Takayanagi H, et al. A new mechanism of bone destruction in rheumatoid arthritis: synovial fibroblasts induce osteoclastogenesis. Biochem Biophys Res Commun. 1997;240(2):279-286. (Pubitemid 27523651)
-
(1997)
Biochemical and Biophysical Research Communications
, vol.240
, Issue.2
, pp. 279-286
-
-
Takayanagi, H.1
Oda, H.2
Yamamoto, S.3
Kawaguchi, H.4
Tanaka, S.5
Nishikawa, T.6
Koshihara, Y.7
-
41
-
-
0034122050
-
Synovial tissue in rheumatoid arthritis is a source of osteoclast differentiation factor
-
DOI 10.1002/1529-0131(200002)43:2<250::AID-ANR3>3.0.CO;2-P
-
Gravallese EM, et al. Synovial tissue in rheumatoid arthritis is a source of osteoclast differentiation factor. Arthritis Rheum. 2000;43(2):250-258. (Pubitemid 30395732)
-
(2000)
Arthritis and Rheumatism
, vol.43
, Issue.2
, pp. 250-258
-
-
Gravallese, E.M.1
Manning, C.2
Tsay, A.3
Naito, A.4
Pan, C.5
Amento, E.6
Goldring, S.R.7
-
42
-
-
33749604848
-
RANKL protein is expressed at the pannus-bone interface at sites of articular bone erosion in rheumatoid arthritis
-
DOI 10.1093/rheumatology/kel045
-
Pettit AR, Walsh NC, Manning C, Goldring SR, Gravallese EM. RANKL protein is expressed at the pannus-bone interface at sites of articular bone erosion in rheumatoid arthritis. Rheumatology (Oxford). 2006;45(9):1068-1076. (Pubitemid 44542091)
-
(2006)
Rheumatology
, vol.45
, Issue.9
, pp. 1068-1076
-
-
Pettit, A.R.1
Walsh, N.C.2
Manning, C.3
Goldring, S.R.4
Gravallese, E.M.5
-
43
-
-
37149026641
-
Treg cells suppress osteoclast formation: A new link between the immune system and bone
-
DOI 10.1002/art.23138
-
Zaiss MM, et al. Treg cells suppress osteoclast formation: a new link between the immune system and bone. Arthritis Rheum. 2007;56(12):4104-4112. (Pubitemid 350262338)
-
(2007)
Arthritis and Rheumatism
, vol.56
, Issue.12
, pp. 4104-4112
-
-
Zaiss, M.M.1
Axmann, R.2
Zwerina, J.3
Polzer, K.4
Guckel, E.5
Skapenko, A.6
Schulze-Koops, H.7
Horwood, N.8
Cope, A.9
Schett, G.10
-
44
-
-
77953639101
-
Regulatory T cells protect from local and systemic bone destruction in arthritis
-
Zaiss MM, et al. Regulatory T cells protect from local and systemic bone destruction in arthritis. J Immunol. 2010;184(12):7238-7246.
-
(2010)
J Immunol
, vol.184
, Issue.12
, pp. 7238-7246
-
-
Zaiss, M.M.1
-
45
-
-
66149146340
-
Activated CD4+CD25+ regulatory T cells inhibit osteoclastogenesis and collagen-induced arthritis
-
Kelchtermans H, Geboes L, Mitera T, Huskens D, Leclercq G, Matthys P. Activated CD4+CD25+ regulatory T cells inhibit osteoclastogenesis and collagen-induced arthritis. Ann Rheum Dis. 2009;68(5):744-750.
-
(2009)
Ann Rheum Dis
, vol.68
, Issue.5
, pp. 744-750
-
-
Kelchtermans, H.1
Geboes, L.2
Mitera, T.3
Huskens, D.4
Leclercq, G.5
Matthys, P.6
-
46
-
-
47249103596
-
CTLA-4 directly inhibits osteoclast formation
-
Axmann R, et al. CTLA-4 directly inhibits osteoclast formation. Ann Rheum Dis. 2008;67(11):1603-1609.
-
(2008)
Ann Rheum Dis
, vol.67
, Issue.11
, pp. 1603-1609
-
-
Axmann, R.1
-
47
-
-
42449098374
-
Results of a two-year followup study of patients with rheumatoid arthritis who received a combination of abatacept and methotrexate
-
DOI 10.1002/art.23397
-
Kremer JM, et al. Results of a two-year followup study of patients with rheumatoid arthritis who received a combination of abatacept and methotrexate. Arthritis Rheum. 2008;58(4):953-963. (Pubitemid 351563996)
-
(2008)
Arthritis and Rheumatism
, vol.58
, Issue.4
, pp. 953-963
-
-
Kremer, J.M.1
Genant, H.K.2
Moreland, L.W.3
Russell, A.S.4
Emery, P.5
Abud-Mendoza, C.6
Szechinski, J.7
Li, T.8
Teng, J.9
Becker, J.-C.10
Westhovens, R.11
-
48
-
-
34247882571
-
Human CD4+CD25+ regulatory T cells inhibit the differentiation of osteoclasts from peripheral blood mononuclear cells
-
DOI 10.1016/j.bbrc.2007.04.042, PII S0006291X07007681
-
Kim YG, Lee CK, Nah SS, Mun SH, Yoo B, Moon HB. Human CD4+CD25+ regulatory T cells inhibit the differentiation of osteoclasts from peripheral blood mononuclear cells. Biochem Biophys Res Commun. 2007;357(4):1046-1052. (Pubitemid 46693677)
-
(2007)
Biochemical and Biophysical Research Communications
, vol.357
, Issue.4
, pp. 1046-1052
-
-
Kim, Y.G.1
Lee, C.-K.2
Nah, S.-S.3
Mun, S.H.4
Yoo, B.5
Moon, H.-B.6
-
49
-
-
49449100184
-
Cytokine-controlled RANKL and osteoprotegerin expression by human and mouse synovial fibroblasts: Fibroblast-mediated pathologic bone resorption
-
Tunyogi-Csapo M, et al. Cytokine-controlled RANKL and osteoprotegerin expression by human and mouse synovial fibroblasts: fibroblast-mediated pathologic bone resorption. Arthritis Rheum. 2008; 58(8):2397-2408.
-
(2008)
Arthritis Rheum
, vol.58
, Issue.8
, pp. 2397-2408
-
-
Tunyogi-Csapo, M.1
-
50
-
-
54449101331
-
IL-6 transsignaling directly induces RANKL on fibroblastlike synovial cells and is involved in RANKL induction by TNFα and IL-17
-
Hashizume M, Hayakawa N, Mihara M. IL-6 transsignaling directly induces RANKL on fibroblastlike synovial cells and is involved in RANKL induction by TNFα and IL-17. Rheumatology (Oxford). 2008;47(11):1635-1640.
-
(2008)
Rheumatology (Oxford)
, vol.47
, Issue.11
, pp. 1635-1640
-
-
Hashizume, M.1
Hayakawa, N.2
Mihara, M.3
-
51
-
-
14944371405
-
IL-1 mediates TNFα osteoclastogenesis
-
Wei S, Kitaura H, Zhou P, Ross FP, Teitelbaum SL. IL-1 mediates TNFα osteoclastogenesis. J Clin Invest. 2005;115(2):282-290.
-
(2005)
J Clin Invest
, vol.115
, Issue.2
, pp. 282-290
-
-
Wei, S.1
Kitaura, H.2
Zhou, P.3
Ross, F.P.4
Teitelbaum, S.L.5
-
52
-
-
0034523328
-
TNF-α induces osteoclastogenesis by direct stimulation of macrophages exposed to permissive levels of RANK ligand
-
Lam J, Takeshita S, Barker JE, Kanagawa O, Ross FP, Teitelbaum SL. TNFα induces osteoclastogenesis by direct stimulation of macrophages exposed to permissive levels of RANK ligand. J Clin Invest. 2000;106(12):1481- 1488. (Pubitemid 32038586)
-
(2000)
Journal of Clinical Investigation
, vol.106
, Issue.12
, pp. 1481-1488
-
-
Lam, J.1
Takeshita, S.2
Barker, J.E.3
Kanagawa, O.4
Ross, F.P.5
Teitelbaum, S.L.6
-
53
-
-
77949454280
-
Interleukin-17A upregulates receptor activator of NFκB on osteoclast precursors
-
Adamopoulos IE, et al. Interleukin-17A upregulates receptor activator of NFκB on osteoclast precursors. Arthritis Res Ther. 2010;12(1):R29.
-
(2010)
Arthritis Res Ther
, vol.12
, Issue.1
-
-
Adamopoulos, I.E.1
-
54
-
-
0036733711
-
Bone and joint destruction in rheumatoid arthritis: What is really happening?
-
Goldring SR. Bone and joint destruction in rheumatoid arthritis: what is really happening? J Rheumatol Suppl. 2002;65:44-48.
-
(2002)
J Rheumatol Suppl
, vol.65
, pp. 44-48
-
-
Goldring, S.R.1
-
55
-
-
72749102524
-
Osteoblast function is compromised at sites of focal bone erosion in inflammatory arthritis
-
Walsh NC, et al. Osteoblast function is compromised at sites of focal bone erosion in inflammatory arthritis. J Bone Miner Res. 2009;24(9):1572-1585.
-
(2009)
J Bone Miner Res
, vol.24
, Issue.9
, pp. 1572-1585
-
-
Walsh, N.C.1
-
56
-
-
33846949349
-
Dickkopf-1 is a master regulator of joint remodeling
-
Diarra D, et al. Dickkopf-1 is a master regulator of joint remodeling. Nat Med. 2007;13(2):156-163.
-
(2007)
Nat Med
, vol.13
, Issue.2
, pp. 156-163
-
-
Diarra, D.1
-
57
-
-
0035954281
-
Head inducer dickkopf-1 is a ligand for Wnt coreceptor LRP6
-
DOI 10.1016/S0960-9822(01)00290-1
-
Semenov MV, Tamai K, Brott BK, Kuhl M, Sokol S, He X. Head inducer Dickkopf-1 is a ligand for Wnt coreceptor LRP6. Curr Biol. 2001;11(12):951-961. (Pubitemid 32589186)
-
(2001)
Current Biology
, vol.11
, Issue.12
, pp. 951-961
-
-
Semenov, M.V.1
Tamai, K.2
Brott, B.K.3
Kuhl, M.4
Sokol, S.5
He, X.6
-
58
-
-
20244373613
-
Canonical Wnt signaling in differentiated osteoblasts controls osteoclast differentiation
-
Glass DA 2nd, et al. Canonical Wnt signaling in differentiated osteoblasts controls osteoclast differentiation. Dev Cell. 2005;8(5):751-764.
-
(2005)
Dev Cell
, vol.8
, Issue.5
, pp. 751-764
-
-
Glass II, D.A.1
-
59
-
-
78649723963
-
Neutralisation of Dkk-1 protects from systemic bone loss during inflammation and reduces sclerostin expression
-
Heiland GR, et al. Neutralisation of Dkk-1 protects from systemic bone loss during inflammation and reduces sclerostin expression. Ann Rheum Dis. 2010;69(12):2152-2159.
-
(2010)
Ann Rheum Dis
, vol.69
, Issue.12
, pp. 2152-2159
-
-
Heiland, G.R.1
-
60
-
-
0034480787
-
Peak bone mass
-
DOI 10.1007/s001980070020
-
Heaney RP, et al. Peak bone mass. Osteoporos Int. 2000;11(12):985-1009. (Pubitemid 32144591)
-
(2000)
Osteoporosis International
, vol.11
, Issue.12
, pp. 985-1009
-
-
Heaney, R.P.1
Abrams, S.2
Dawson-Hughes, B.3
Looker, A.4
Looker, A.5
Marcus, R.6
Matkovic, V.7
Weaver, C.8
-
62
-
-
84967614664
-
Sex steroids and the construction and conservation of the adult skeleton
-
DOI 10.1210/er.23.3.279
-
Riggs BL, Khosla S, Melton LJ 3rd. Sex steroids and the construction and conservation of the adult skeleton. Endocr Rev. 2002;23(3):279-302. (Pubitemid 34651948)
-
(2002)
Endocrine Reviews
, vol.23
, Issue.3
, pp. 279-302
-
-
Riggs, B.L.1
Khosla, S.2
Melton III, L.J.3
-
63
-
-
13444256417
-
Mechanisms of sex steroid effects on bone
-
DOI 10.1016/j.bbrc.2004.11.097, Vertebrate Skeletal Biology
-
Syed F, Khosla S. Mechanisms of sex steroid effects on bone. Biochem Biophys Res Commun. 2005;328(3):688-696. (Pubitemid 40214350)
-
(2005)
Biochemical and Biophysical Research Communications
, vol.328
, Issue.3
, pp. 688-696
-
-
Syed, F.1
Khosla, S.2
-
64
-
-
33645059209
-
Preventing osteoporosis-related fractures: An overview
-
Gass M, Dawson-Hughes B. Preventing osteoporosis-related fractures: an overview. Am J Med. 2006;119(4 suppl 1):S3-S11.
-
(2006)
Am J Med
, vol.119
, Issue.4 SUPPL. 1
-
-
Gass, M.1
Dawson-Hughes, B.2
-
65
-
-
0031955217
-
A unitary model for involutional osteoporosis: Estrogen deficiency causes both type I and type II osteoporosis in postmenopausal women and contributes to bone loss in aging men
-
DOI 10.1359/jbmr.1998.13.5.763
-
Riggs BL, Khosla S, Melton LJ 3rd. A unitary model for involutional osteoporosis: estrogen deficiency causes both type I and type II osteoporosis in post-menopausal women and contributes to bone loss in aging men. J Bone Miner Res. 1998;13(5):763-773. (Pubitemid 28224192)
-
(1998)
Journal of Bone and Mineral Research
, vol.13
, Issue.5
, pp. 763-773
-
-
Riggs, B.L.1
Khosla, S.2
Melton III, L.J.3
-
66
-
-
34548321649
-
Estrogen and CD4+ T cells
-
DOI 10.1097/BOR.0b013e328277ef2a, PII 0000228120070900000004
-
Pernis AB. Estrogen and CD4+ T cells. Curr Opin Rheumatol. 2007;19(5):414-420. (Pubitemid 47344231)
-
(2007)
Current Opinion in Rheumatology
, vol.19
, Issue.5
, pp. 414-420
-
-
Pernis, A.B.1
-
67
-
-
0033708837
-
Estrogen deficiency induces bone loss by enhancing T-cell production of TNF-alpha
-
Cenci S, et al. Estrogen deficiency induces bone loss by enhancing T-cell production of TNF-alpha. J Clin Invest. 2000;106(10):1229-1237.
-
(2000)
J Clin Invest
, vol.106
, Issue.10
, pp. 1229-1237
-
-
Cenci, S.1
-
68
-
-
44949083462
-
Estrogen deficiency increases osteoclastogenesis up-regulating T cells activity: A key mechanism in osteoporosis
-
D'Amelio P, et al. Estrogen deficiency increases osteoclastogenesis up-regulating T cells activity: a key mechanism in osteoporosis. Bone. 2008;43(1):92-100.
-
(2008)
Bone
, vol.43
, Issue.1
, pp. 92-100
-
-
D'Amelio, P.1
-
69
-
-
2042545404
-
Estrogen deficiency accelerates murine autoimmune arthritis associated with receptor activator of nuclear factor-kappaB ligand-mediated osteoclastogenesis
-
DOI 10.1210/en.2003-1536
-
Yoneda T, et al. Estrogen deficiency accelerates murine autoimmune arthritis associated with receptor activator of nuclear factor-kappa B ligand-mediated osteoclastogenesis. Endocrinology. 2004;145(5):2384-2391. (Pubitemid 38535068)
-
(2004)
Endocrinology
, vol.145
, Issue.5
, pp. 2384-2391
-
-
Yoneda, T.1
Ishimaru, N.2
Arakaki, R.3
Kobayashi, M.4
Izawa, T.5
Moriyama, K.6
Hayashi, Y.7
-
70
-
-
0037398261
-
Role of RANK ligand in mediating increased bone resorption in early postmenopausal women
-
DOI 10.1172/JCI200317215
-
Eghbali-Fatourechi G, Khosla S, Sanyal A, Boyle WJ, Lacey DL, Riggs BL. Role of RANK ligand in mediating increased bone resorption in early postmenopausal women. J Clin Invest. 2003;111(8):1221-1230. (Pubitemid 36519939)
-
(2003)
Journal of Clinical Investigation
, vol.111
, Issue.8
, pp. 1221-1230
-
-
Eghbali-Fatourechi, G.1
Khosla, S.2
Sanyal, A.3
Boyle, W.J.4
Lacey, D.L.5
Riggs, B.L.6
-
71
-
-
49949119153
-
Pharmacologic stem cell based intervention as a new approach to osteoporosis treatment in rodents
-
Yamaza T, et al. Pharmacologic stem cell based intervention as a new approach to osteoporosis treatment in rodents. PLoS One. 2008;3(7):e2615.
-
(2008)
PLoS One
, vol.3
, Issue.7
-
-
Yamaza, T.1
-
72
-
-
77955842458
-
T cells: Critical bone regulators in health and disease
-
Pacifici R. T cells: critical bone regulators in health and disease. Bone. 2010;47(3):461-471.
-
(2010)
Bone
, vol.47
, Issue.3
, pp. 461-471
-
-
Pacifici, R.1
-
73
-
-
33846017422
-
T lymphocyte-deficient mice lose trabecular bone mass with ovariectomy
-
Lee SK, et al. T lymphocyte-deficient mice lose trabecular bone mass with ovariectomy. J Bone Miner Res. 2006;21(11):1704-1712.
-
(2006)
J Bone Miner Res
, vol.21
, Issue.11
, pp. 1704-1712
-
-
Lee, S.K.1
-
74
-
-
64649084316
-
Lymphocytes and the Dap12 adaptor are key regulators of osteoclast activation associated with gonadal failure
-
Anginot A, Dacquin R, Mazzorana M, Jurdic P. Lymphocytes and the Dap12 adaptor are key regulators of osteoclast activation associated with gonadal failure. PLoS One. 2007;2(7):e585.
-
(2007)
PLoS One
, vol.2
, Issue.7
-
-
Anginot, A.1
Dacquin, R.2
Mazzorana, M.3
Jurdic, P.4
-
75
-
-
0025746581
-
Pathophysiology of primary hyperparathyroidism
-
Spiegel AM. Pathophysiology of primary hyperparathyroidism. J Bone Miner Res. 1991;6(suppl 2):S15-S17.
-
(1991)
J Bone Miner Res
, vol.6
, Issue.SUPPL. 2
-
-
Spiegel, A.M.1
-
76
-
-
48149095459
-
T cells potentiate PTH-induced cortical bone loss through CD40L signaling
-
Gao Y, et al. T cells potentiate PTH-induced cortical bone loss through CD40L signaling. Cell Metab. 2008;8(2):132-145.
-
(2008)
Cell Metab
, vol.8
, Issue.2
, pp. 132-145
-
-
Gao, Y.1
-
77
-
-
77957891185
-
Disruption of PTH receptor 1 in T cells protects against PTH-induced bone loss
-
Tawfeek H, et al. Disruption of PTH receptor 1 in T cells protects against PTH-induced bone loss. PLoS One. 2010;5(8):e12290.
-
(2010)
PLoS One
, vol.5
, Issue.8
-
-
Tawfeek, H.1
-
78
-
-
34248577022
-
Molecular and cellular mechanisms of the anabolic effect of intermittent PTH
-
DOI 10.1016/j.bone.2007.03.017, PII S8756328207001731
-
Jilka RL. Molecular and cellular mechanisms of the anabolic effect of intermittent PTH. Bone. 2007;40(6):1434-1446. (Pubitemid 46756429)
-
(2007)
Bone
, vol.40
, Issue.6
, pp. 1434-1446
-
-
Jilka, R.L.1
-
79
-
-
70349573790
-
Clinical update on teriparatide
-
File E, Deal C. Clinical update on teriparatide. Curr Rheumatol Rep. 2009;11(3):169-176.
-
(2009)
Curr Rheumatol Rep
, vol.11
, Issue.3
, pp. 169-176
-
-
File, E.1
Deal, C.2
-
80
-
-
34250823973
-
Minireview: Targeting the Wnt/beta-catenin pathway to regulate bone formation in the adult skeleton
-
DOI 10.1210/en.2007-0270
-
Baron R, Rawadi G. Targeting the Wnt/beta-catenin pathway to regulate bone formation in the adult skeleton. Endocrinology. 2007;148(6):2635-2643. (Pubitemid 46984775)
-
(2007)
Endocrinology
, vol.148
, Issue.6
, pp. 2635-2643
-
-
Baron, R.1
Rawadi, G.2
-
81
-
-
0242268524
-
Osteoblastic cells regulate the haematopoietic stem cell niche
-
DOI 10.1038/nature02040
-
Calvi LM, et al. Osteoblastic cells regulate the haematopoietic stem cell niche. Nature. 2003;425(6960):841-846. (Pubitemid 37351468)
-
(2003)
Nature
, vol.425
, Issue.6960
, pp. 841-846
-
-
Calvi, L.M.1
Adams, G.B.2
Weibrecht, K.W.3
Weber, J.M.4
Olson, D.P.5
Knight, M.C.6
Martin, R.P.7
Schipani, E.8
Divieti, P.9
Bringhurst, F.R.10
Milner, L.A.11
Kronenberg, H.M.12
Scadden, D.T.13
-
82
-
-
0242363225
-
Identification of the haematopoietic stem cell niche and control of the niche size
-
DOI 10.1038/nature02041
-
Zhang J, et al. Identification of the haematopoietic stem cell niche and control of the niche size. Nature. 2003;425(6960):836-841. (Pubitemid 37351467)
-
(2003)
Nature
, vol.425
, Issue.6960
, pp. 836-841
-
-
Zhang, J.1
Niu, C.2
Ye, L.3
Huang, H.4
He, X.5
Tong, W.-G.6
Ross, J.7
Haug, J.8
Johnson, T.9
Feng, J.Q.10
Harris, S.11
Wiedemann, L.M.12
Mishina, Y.13
Li, L.14
-
83
-
-
67449092765
-
Cancer stem cells and their niche
-
Iwasaki H, Suda T. Cancer stem cells and their niche. Cancer Sci. 2009;100(7):1166-1172.
-
(2009)
Cancer Sci
, vol.100
, Issue.7
, pp. 1166-1172
-
-
Iwasaki, H.1
Suda, T.2
-
84
-
-
33644760436
-
A study of the biological receptor activator of nuclear factor-κB ligand inhibitor, denosumab, in patients with multiple myeloma or bone metastases from breast cancer
-
Body JJ, et al. A study of the biological receptor activator of nuclear factor-κB ligand inhibitor, denosumab, in patients with multiple myeloma or bone metastases from breast cancer. Clin Cancer Res. 2006;12(4):1221-1228.
-
(2006)
Clin Cancer Res
, vol.12
, Issue.4
, pp. 1221-1228
-
-
Body, J.J.1
-
85
-
-
70349488703
-
An open-label, phase 2 trial of denosumab in the treatment of relapsed or plateau-phase multiple myeloma
-
Vij R, et al. An open-label, phase 2 trial of denosumab in the treatment of relapsed or plateau-phase multiple myeloma. Am J Hematol. 2009;84(10):650-656.
-
(2009)
Am J Hematol
, vol.84
, Issue.10
, pp. 650-656
-
-
Vij, R.1
-
86
-
-
73949150107
-
Effect of bisphosphonates on pain and quality of life in patients with bone metastases
-
Costa L, Major PP. Effect of bisphosphonates on pain and quality of life in patients with bone metastases. Nat Clin Pract Oncol. 2009;6(3):163-174.
-
(2009)
Nat Clin Pract Oncol
, vol.6
, Issue.3
, pp. 163-174
-
-
Costa, L.1
Major, P.P.2
-
88
-
-
14344250737
-
Fracture risk with multiple myeloma: A population-based study
-
DOI 10.1359/JBMR.041131
-
Melton LJ 3rd, Kyle RA, Achenbach SJ, Oberg AL, Rajkumar SV. Fracture risk with multiple myeloma: a population-based study. J Bone Miner Res. 2005;20(3):487-493. (Pubitemid 40293498)
-
(2005)
Journal of Bone and Mineral Research
, vol.20
, Issue.3
, pp. 487-493
-
-
Melton III, L.J.1
Kyle, R.A.2
Achenbach, S.J.3
Oberg, A.L.4
Rajkumar, S.V.5
-
89
-
-
0342322717
-
Macrophage inflammatory protein 1-alpha is a potential osteoclast stimulatory factor in multiple myeloma
-
Choi SJ, et al. Macrophage inflammatory protein 1-alpha is a potential osteoclast stimulatory factor in multiple myeloma. Blood. 2000;96(2):671-675. (Pubitemid 30463390)
-
(2000)
Blood
, vol.96
, Issue.2
, pp. 671-675
-
-
Choi, S.J.1
Cruz, J.C.2
Craig, F.3
Chung, H.4
Devlin, R.D.5
Roodman, G.D.6
Alsina, M.7
-
90
-
-
4644343663
-
The RANK/RANK ligand system is involved in interleukin-6 and interleukin-11 up-regulation by human myeloma cells in the bone marrow microenvironment
-
Giuliani N, Colla S, Morandi F, Rizzoli V. The RANK/RANK ligand system is involved in interleukin-6 and interleukin-11 up-regulation by human myeloma cells in the bone marrow microenvironment. Haematologica. 2004;89(9):1118-1123. (Pubitemid 39295483)
-
(2004)
Haematologica
, vol.89
, Issue.9
, pp. 1118-1123
-
-
Giuliani, N.1
Colla, S.2
Morandi, F.3
Rizzoli, V.4
-
91
-
-
1542313900
-
IL-3 expression by myeloma cells increases both osteoclast formation and growth of myeloma cells
-
DOI 10.1182/blood-2003-06-1992
-
Lee JW, et al. IL-3 expression by myeloma cells increases both osteoclast formation and growth of myeloma cells. Blood. 2004;103(6):2308-2315. (Pubitemid 38326251)
-
(2004)
Blood
, vol.103
, Issue.6
, pp. 2308-2315
-
-
Lee, J.W.1
Chung, H.Y.2
Ehrlich, L.A.3
Jelinek, D.F.4
Callander, N.S.5
Roodman, G.D.6
Choi, S.J.7
-
92
-
-
0037108435
-
Osteoprotegerin is bound, internalized, and degraded by multiple myeloma cells
-
Standal T, et al. Osteoprotegerin is bound, internalized, and degraded by multiple myeloma cells. Blood. 2002;100(8):3002-3007.
-
(2002)
Blood
, vol.100
, Issue.8
, pp. 3002-3007
-
-
Standal, T.1
-
93
-
-
6844252283
-
Long-term pamidronate treatment of advanced multiple myeloma patients reduces skeletal events
-
Berenson JR, et al. Long-term pamidronate treatment of advanced multiple myeloma patients reduces skeletal events. Myeloma Aredia Study Group. J Clin Oncol. 1998;16(2):593-602. (Pubitemid 28135605)
-
(1998)
Journal of Clinical Oncology
, vol.16
, Issue.2
, pp. 593-602
-
-
Berenson, J.R.1
Lichtenstein, A.2
Porter, L.3
Dimopoulos, M.A.4
Bordoni, R.5
George, S.6
Lipton, A.7
Keller, A.8
Ballester, O.9
Kovacs, M.10
Blacklock, H.11
Bell, R.12
Simeone, J.F.13
Reitsma, D.J.14
Heffernan, M.15
Seaman, J.16
Knight, R.D.17
-
94
-
-
0036758243
-
Clinical evaluation of onset of analgesia using intravenous pamidronate in metastatic bone pain
-
Petcu EB, Schug SA, Smith H. Clinical evaluation of onset of analgesia using intravenous pamidronate in metastatic bone pain. J Pain Symptom Manage. 2002;24(3):281-284.
-
(2002)
J Pain Symptom Manage
, vol.24
, Issue.3
, pp. 281-284
-
-
Petcu, E.B.1
Schug, S.A.2
Smith, H.3
-
95
-
-
20244364254
-
Effector gammadelta T cells and tumor cells as immune targets of zoledronic acid in multiple myeloma
-
DOI 10.1038/sj.leu.2403693
-
Mariani S, et al. Effector gammadelta T cells and tumor cells as immune targets of zoledronic acid in multiple myeloma. Leukemia. 2005;19(4):664-670. (Pubitemid 40521173)
-
(2005)
Leukemia
, vol.19
, Issue.4
, pp. 664-670
-
-
Mariani, S.1
Muraro, M.2
Pantaleoni, F.3
Fiore, F.4
Nuschak, B.5
Peola, S.6
Foglietta, M.7
Palumbo, A.8
Coscia, M.9
Castella, B.10
Bruno, B.11
Bertieri, R.12
Boano, L.13
Boccadoro, M.14
Massaia, M.15
-
96
-
-
0346363760
-
The Role of the Wnt-Signaling Antagonist DKK1 in the Development of Osteolytic Lesions in Multiple Myeloma
-
DOI 10.1056/NEJMoa030847
-
Tian E, et al. The role of the Wnt-signaling antagonist DKK1 in the development of osteolytic lesions in multiple myeloma. N Engl J Med. 2003; 349(26):2483-2494. (Pubitemid 38010074)
-
(2003)
New England Journal of Medicine
, vol.349
, Issue.26
, pp. 2483-2494
-
-
Tian, E.1
Zhan, F.2
Walker, R.3
Rasmussen, E.4
Ma, Y.5
Barlogie, B.6
Shaughnessy Jr., J.D.7
-
97
-
-
67650431302
-
Anti-DKK1 mAb (BHQ880) as a potential therapeutic agent for multiple myeloma
-
Fulciniti M, et al. Anti-DKK1 mAb (BHQ880) as a potential therapeutic agent for multiple myeloma. Blood. 2009;114(2):371-379.
-
(2009)
Blood
, vol.114
, Issue.2
, pp. 371-379
-
-
Fulciniti, M.1
-
98
-
-
0034730327
-
The osteoclast differentiation factor osteoprotegerin-ligand is essential for mammary gland development
-
Fata JE, et al. The osteoclast differentiation factor osteoprotegerin-ligand is essential for mammary gland development. Cell. 2000;103(1):41-50.
-
(2000)
Cell
, vol.103
, Issue.1
, pp. 41-50
-
-
Fata, J.E.1
-
99
-
-
78149284013
-
Osteoclast differentiation factor RANKL controls development of progestin-driven mammary cancer
-
Schramek D, et al. Osteoclast differentiation factor RANKL controls development of progestin-driven mammary cancer. Nature. 2010;468(7320):98-102.
-
(2010)
Nature
, vol.468
, Issue.7320
, pp. 98-102
-
-
Schramek, D.1
-
100
-
-
78149284767
-
RANK ligand mediates progestin-induced mammary epithelial proliferation and carcinogenesis
-
Gonzalez-Suarez E, et al. RANK ligand mediates progestin-induced mammary epithelial proliferation and carcinogenesis. Nature. 2010;468(7320):103-107.
-
(2010)
Nature
, vol.468
, Issue.7320
, pp. 103-107
-
-
Gonzalez-Suarez, E.1
-
101
-
-
33645453481
-
Regulation of cancer cell migration and bone metastasis by RANKL
-
Jones DH, et al. Regulation of cancer cell migration and bone metastasis by RANKL. Nature. 2006; 440(7084):692-696.
-
(2006)
Nature
, vol.440
, Issue.7084
, pp. 692-696
-
-
Jones, D.H.1
-
102
-
-
9144236929
-
Osteoblast responses to bacterial pathogens: A previously unappreciated role for bone-forming cells in host defense and disease progression
-
DOI 10.1385/IR:30:3:291
-
Marriott I. Osteoblast responses to bacterial pathogens: a previously unappreciated role for boneforming cells in host defense and disease progression. Immunol Res. 2004;30(3):291-308. (Pubitemid 39546231)
-
(2004)
Immunologic Research
, vol.30
, Issue.3
, pp. 291-308
-
-
Marriott, I.1
-
104
-
-
79951610661
-
Inflammation and uncoupling as mechanisms of periodontal bone loss
-
Graves DT, Li J, Cochran DL. Inflammation and uncoupling as mechanisms of periodontal bone loss. J Dent Res. 2011;90(2):143-153.
-
(2011)
J Dent Res
, vol.90
, Issue.2
, pp. 143-153
-
-
Graves, D.T.1
Li, J.2
Cochran, D.L.3
-
105
-
-
77951260924
-
The role of pattern-recognition receptors in innate immunity: Update on Toll-like receptors
-
Kawai T, Akira S. The role of pattern-recognition receptors in innate immunity: update on Toll-like receptors. Nat Immunol. 2010;11(5):373-384.
-
(2010)
Nat Immunol
, vol.11
, Issue.5
, pp. 373-384
-
-
Kawai, T.1
Akira, S.2
-
106
-
-
41449102471
-
Taking a Toll on the bones: Regulation of bone metabolism by innate immune regulators
-
DOI 10.1080/08916930701694469, PII 789050133, Osteoimmunology in Skeletal Cell Biology and Disease
-
Bar-Shavit Z. Taking a toll on the bones: regulation of bone metabolism by innate immune regulators. Autoimmunity. 2008;41(3):195-203. (Pubitemid 351454989)
-
(2008)
Autoimmunity
, vol.41
, Issue.3
, pp. 195-203
-
-
Bar-Shavit, Z.1
-
107
-
-
0026069940
-
Evidence for interleukin-1β production by cultured normal human osteoblast-like cells
-
Keeting PE, et al. Evidence for interleukin-1β production by cultured normal human osteoblast-like cells. J Bone Miner Res. 1991;6(8):827-833.
-
(1991)
J Bone Miner Res
, vol.6
, Issue.8
, pp. 827-833
-
-
Keeting, P.E.1
-
108
-
-
0025259989
-
IL-6 is produced by osteoblasts and induces bone resorption
-
Ishimi Y, et al. IL-6 is produced by osteoblasts and induces bone resorption. J Immunol. 1990; 145(10):3297-3303.
-
(1990)
J Immunol
, vol.145
, Issue.10
, pp. 3297-3303
-
-
Ishimi, Y.1
-
109
-
-
0034440540
-
Impaired bone resorption by lipopolysaccharide in vivo in mice deficient in the prostaglandin e receptor EP4 subtype
-
DOI 10.1128/IAI.68.12.6819-6825.2000
-
Sakuma Y, et al. Impaired bone resorption by lipopolysaccharide in vivo in mice deficient in the prostaglandin E receptor EP4 subtype. Infect Immun. 2000;68(12):6819-6825. (Pubitemid 32463389)
-
(2000)
Infection and Immunity
, vol.68
, Issue.12
, pp. 6819-6825
-
-
Sakuma, Y.1
Tanaka, K.2
Suda, M.3
Komatsu, Y.4
Yasoda, A.5
Miura, M.6
Ozasa, A.7
Narumiya, S.8
Sugimoto, Y.9
Ichikawa, A.10
Ushikubi, F.11
Nakao, K.12
-
110
-
-
35348948929
-
Proinflammatory cytokine expression in cyclooxygenase-2-deficient primary osteoblasts
-
He J, Tomlinson R, Coon D, Gulati A, Cowan C. Proinflammatory cytokine expression in cyclooxygenase-2-deficient primary osteoblasts. J Endod. 2007;33(11):1309-1312.
-
(2007)
J Endod
, vol.33
, Issue.11
, pp. 1309-1312
-
-
He, J.1
Tomlinson, R.2
Coon, D.3
Gulati, A.4
Cowan, C.5
-
111
-
-
0036073481
-
Bacterium-induced CXCL10 secretion by osteoblasts can be mediated in part through toll-like receptor 4
-
DOI 10.1128/IAI.70.8.4075-4082.2002
-
Gasper NA, Petty CC, Schrum LW, Marriott I, Bost KL. Bacterium-induced CXCL10 secretion by osteoblasts can be mediated in part through toll-like receptor 4. Infect Immun. 2002;70(8):4075-4082. (Pubitemid 34790915)
-
(2002)
Infection and Immunity
, vol.70
, Issue.8
, pp. 4075-4082
-
-
Gasper, N.A.1
Petty, C.C.2
Schrum, L.W.3
Marriott, I.4
Bost, K.L.5
-
112
-
-
78649443034
-
Molecular mechanisms of the inhibitory effect of lipopolysaccharide (LPS) on osteoblast differentiation
-
Bandow K, et al. Molecular mechanisms of the inhibitory effect of lipopolysaccharide (LPS) on osteoblast differentiation. Biochem Biophys Res Commun. 2010;402(4):755-761.
-
(2010)
Biochem Biophys Res Commun
, vol.402
, Issue.4
, pp. 755-761
-
-
Bandow, K.1
-
113
-
-
0344628647
-
Hard labour: Bacterial infection of the skeleton
-
DOI 10.1016/j.tim.2003.10.005
-
Henderson B, Nair SP. Hard labour: bacterial infection of the skeleton. Trends Microbiol. 2003;11(12):570-577. (Pubitemid 37500908)
-
(2003)
Trends in Microbiology
, vol.11
, Issue.12
, pp. 570-577
-
-
Henderson, B.1
Nair, S.P.2
-
114
-
-
79952695473
-
Causative agents of osteomyelitis induce death domain - Containing TNF - Related apoptosis - Inducing ligand receptor expression on osteoblasts
-
Young AB, Cooley ID, Chauhan VS, Marriott I. Causative agents of osteomyelitis induce death domain - containing TNF - related apoptosis - inducing ligand receptor expression on osteoblasts. Bone. 2011;48(4):857-863.
-
(2011)
Bone
, vol.48
, Issue.4
, pp. 857-863
-
-
Young, A.B.1
Cooley, I.D.2
Chauhan, V.S.3
Marriott, I.4
-
115
-
-
3042589918
-
Staphylococcus aureus - Induced tumor necrosis factor - Related apoptosis - Inducing ligand expression mediates apoptosis and caspase- 8 activation in infected osteoblasts
-
Alexander EH, Rivera FA, Marriott I, Anguita J, Bost KL, Hudson MC. Staphylococcus aureus - induced tumor necrosis factor - related apoptosis - inducing ligand expression mediates apoptosis and caspase- 8 activation in infected osteoblasts. BMC Microbiol. 2003;3:5.
-
(2003)
BMC Microbiol
, vol.3
, pp. 5
-
-
Alexander, E.H.1
Rivera, F.A.2
Marriott, I.3
Anguita, J.4
Bost, K.L.5
Hudson, M.C.6
-
116
-
-
58149354657
-
Osteoblasts participate in the innate immunity of the bone by producing human β-defensin-3
-
Varoga D, et al. Osteoblasts participate in the innate immunity of the bone by producing human β-defensin-3. Histochem Cell Biol. 2009;131(2):207-218.
-
(2009)
Histochem Cell Biol
, vol.131
, Issue.2
, pp. 207-218
-
-
Varoga, D.1
-
117
-
-
57249084060
-
The role of human β-defensin-2 in bone
-
Varoga D, et al. The role of human β-defensin-2 in bone. J Anat. 2008;213(6):749-757.
-
(2008)
J Anat
, vol.213
, Issue.6
, pp. 749-757
-
-
Varoga, D.1
-
118
-
-
0036681842
-
Stimulation by toll-like receptors inhibits osteoclast differentiation
-
Takami M, Kim N, Rho J, Choi Y. Stimulation by toll-like receptors inhibits osteoclast differentiation. J Immunol. 2002;169(3):1516-1523. (Pubitemid 34809198)
-
(2002)
Journal of Immunology
, vol.169
, Issue.3
, pp. 1516-1523
-
-
Takami, M.1
Kim, N.2
Rho, J.3
Choi, Y.4
-
119
-
-
73349101077
-
Inhibition of RANK expression and osteoclastogenesis by TLRs and IFN-γ in human osteoclast precursors
-
Ji JD, et al. Inhibition of RANK expression and osteoclastogenesis by TLRs and IFN-γ in human osteoclast precursors. J Immunol. 2009;183(11):7223-7233.
-
(2009)
J Immunol
, vol.183
, Issue.11
, pp. 7223-7233
-
-
Ji, J.D.1
-
120
-
-
0031790387
-
Human osteoclasts and osteoclast-like cells synthesize and release high basal and inflammatory stimulated levels of the potent chemokine interleukin- 8
-
Rothe L, et al. Human osteoclasts and osteoclast-like cells synthesize and release high basal and inflammatory stimulated levels of the potent chemokine interleukin-8. Endocrinology. 1998;139(10):4353-4363. (Pubitemid 28513725)
-
(1998)
Endocrinology
, vol.139
, Issue.10
, pp. 4353-4363
-
-
Rothe, L.1
Collin-Osdoby, P.2
Chen, Y.3
Sunyer, T.4
Chaudhary, L.5
Tsay, A.6
Goldring, S.7
Avioli, L.8
Osdoby, P.9
-
121
-
-
67649407259
-
Mouse macrophages primed with alendronate down-regulate monocyte chemoattractant protein-1 (MCP-1) and macrophage inflammatory protein-1alpha (MIP-1alpha) production in response to Toll-like receptor (TLR) 2 and TLR4 agonist via Smad3 activation
-
Masuda T, Deng X, Tamai R. Mouse macrophages primed with alendronate down-regulate monocyte chemoattractant protein-1 (MCP-1) and macrophage inflammatory protein-1alpha (MIP-1alpha) production in response to Toll-like receptor (TLR) 2 and TLR4 agonist via Smad3 activation. Int Immunopharmacol. 2009;9(9):1115-1121.
-
(2009)
Int Immunopharmacol
, vol.9
, Issue.9
, pp. 1115-1121
-
-
Masuda, T.1
Deng, X.2
Tamai, R.3
-
122
-
-
77955475327
-
Cross talk between the bone and immune systems: Osteoclasts function as antigen-presenting cells and activate CD4+ and CD8+ T cells
-
Li H, Hong S, Qian J, Zheng Y, Yang J, Yi Q. Cross talk between the bone and immune systems: osteoclasts function as antigen-presenting cells and activate CD4+ and CD8+ T cells. Blood. 2010;116(2):210-217.
-
(2010)
Blood
, vol.116
, Issue.2
, pp. 210-217
-
-
Li, H.1
Hong, S.2
Qian, J.3
Zheng, Y.4
Yang, J.5
Yi, Q.6
-
123
-
-
33646836925
-
Systematic review: Bisphosphonates and osteonecrosis of the jaws
-
Woo SB, Hellstein JW, Kalmar JR. Narrative [corrected] review: bisphosphonates and osteonecrosis of the jaws. Ann Intern Med. 2006;144(10):753-761. (Pubitemid 46780635)
-
(2006)
Annals of Internal Medicine
, vol.144
, Issue.10
, pp. 753-761
-
-
Woo, S.-B.1
Hellstein, J.W.2
Kalmar, J.R.3
-
124
-
-
77950658125
-
Effects of antiresorptive agents on osteomyelitis: Novel insights into the pathogenesis of osteonecrosis of the jaw
-
Li D, et al. Effects of antiresorptive agents on osteomyelitis: novel insights into the pathogenesis of osteonecrosis of the jaw. Ann N Y Acad Sci. 2010;1192:84-94.
-
(2010)
Ann N Y Acad Sci
, vol.1192
, pp. 84-94
-
-
Li, D.1
-
125
-
-
77954620010
-
Bisphosphonates cause osteonecrosis of the jaw-like disease in mice
-
Bi Y, et al. Bisphosphonates cause osteonecrosis of the jaw-like disease in mice. Am J Pathol. 2010;177(1):280-290.
-
(2010)
Am J Pathol
, vol.177
, Issue.1
, pp. 280-290
-
-
Bi, Y.1
-
126
-
-
77953454405
-
Effects of denosumab on bone mineral density and bone turnover in postmenopausal women transitioning from alendronate therapy
-
Kendler DL, et al. Effects of denosumab on bone mineral density and bone turnover in postmenopausal women transitioning from alendronate therapy. J Bone Miner Res. 2010;25(1):72-81.
-
(2010)
J Bone Miner Res
, vol.25
, Issue.1
, pp. 72-81
-
-
Kendler, D.L.1
-
127
-
-
65449137137
-
Denosumab: Anti-RANKL antibody
-
Miller PD. Denosumab: anti-RANKL antibody. Curr Osteoporos Rep. 2009;7(1):18-22.
-
(2009)
Curr Osteoporos Rep
, vol.7
, Issue.1
, pp. 18-22
-
-
Miller, P.D.1
|