메뉴 건너뛰기




Volumn 40, Issue 3, 2013, Pages 2589-2598

IL-6 gene polymorphisms and CAD risk: A meta-analysis

Author keywords

174 G C; 572 G C; Coronary artery disease; IL 6 gene; Polymorphism

Indexed keywords

INTERLEUKIN 6;

EID: 84878417334     PISSN: 03014851     EISSN: 15734978     Source Type: Journal    
DOI: 10.1007/s11033-012-2345-x     Document Type: Article
Times cited : (20)

References (53)
  • 1
    • 77649126524 scopus 로고    scopus 로고
    • Heart disease and stroke statistics-2010 update: A report from the American Heart Association
    • Writing group members 10.1161/CIRCULATIONAHA.109.192667
    • Writing group members, Lloyd-Jones D, Adams RJ, Brown TM, Carnethon M, Dai S et al (2010) Heart disease and stroke statistics-2010 update: a report from the American Heart Association. Circulation 121(7):46-215
    • (2010) Circulation , vol.121 , Issue.7 , pp. 46-215
    • Lloyd-Jones, D.1    Adams, R.J.2    Brown, T.M.3    Carnethon, M.4    Dai, S.5
  • 2
    • 0033537343 scopus 로고    scopus 로고
    • Lifetime risk of developing coronary heart disease
    • 10023892 10.1016/S0140-6736(98)10279-9 1:STN:280:DyaK1M7ks1CqtQ%3D%3D
    • Lloyd-Jones DM, Larson MG, Beiser A, Levy D (1999) Lifetime risk of developing coronary heart disease. Lancet 353:89-92
    • (1999) Lancet , vol.353 , pp. 89-92
    • Lloyd-Jones, D.M.1    Larson, M.G.2    Beiser, A.3    Levy, D.4
  • 3
    • 0032080553 scopus 로고    scopus 로고
    • Interactive role of infection, inflammation and traditional risk factors in atherosclerosis and coronary artery disease
    • 9581711 10.1016/S0735-1097(98)00093-X 1:STN:280:DyaK1c3ktVynsQ%3D%3D
    • Mehta JL, Saldeen TG, Rand K (1998) Interactive role of infection, inflammation and traditional risk factors in atherosclerosis and coronary artery disease. J Am Coll Cardiol 31(6):1217-1225
    • (1998) J Am Coll Cardiol , vol.31 , Issue.6 , pp. 1217-1225
    • Mehta, J.L.1    Saldeen, T.G.2    Rand, K.3
  • 4
    • 17644412023 scopus 로고    scopus 로고
    • Inflammation, atherosclerosis, and coronary artery disease
    • 10.1056/NEJMra043430 1:CAS:528:DC%2BD2MXjsFCltrc%3D
    • Hansson GK (2005) Inflammation, atherosclerosis, and coronary artery disease. N Eng J Med 352:1685-1695
    • (2005) N Eng J Med , vol.352 , pp. 1685-1695
    • Hansson, G.K.1
  • 5
    • 0032943709 scopus 로고    scopus 로고
    • C-reactive protein in healthy subjects: Associations with obesity, insulin resistance, and endothelial dysfunction: A potential role for cytokines originating from adipose tissue?
    • 10195925 10.1161/01.ATV.19.4.972 1:CAS:528:DyaK1MXislaru70%3D
    • Yudkin JS, Stehouwer CD, Emeis JJ, Coppack SW (1999) C-reactive protein in healthy subjects: associations with obesity, insulin resistance, and endothelial dysfunction: a potential role for cytokines originating from adipose tissue? Arterioscler Thromb Vasc Biol 19:972-978
    • (1999) Arterioscler Thromb Vasc Biol , vol.19 , pp. 972-978
    • Yudkin, J.S.1    Stehouwer, C.D.2    Emeis, J.J.3    Coppack, S.W.4
  • 6
    • 0025214567 scopus 로고
    • Interleukin-6 stimulates c-myc expression and proliferation of cultured vascular smooth muscle cells
    • 2346497 1:CAS:528:DyaK3cXitleksbw%3D
    • Nabata T, Morimoto S, Koh E, Shiraishi T, Ogihara T (1990) Interleukin-6 stimulates c-myc expression and proliferation of cultured vascular smooth muscle cells. Biochem Int 20:445-453
    • (1990) Biochem Int , vol.20 , pp. 445-453
    • Nabata, T.1    Morimoto, S.2    Koh, E.3    Shiraishi, T.4    Ogihara, T.5
  • 7
    • 0034759210 scopus 로고    scopus 로고
    • Interleukin-6 and acute coronary syndrome
    • 10.1002/clc.4960241103
    • Ikeda U, Ito L, shimad K (2001) Interleukin-6 and acute coronary syndrome. Clin Cardiol 24:1574-1583
    • (2001) Clin Cardiol , vol.24 , pp. 1574-1583
    • Ikeda, U.1    Ito, L.2    Shimad, K.3
  • 8
    • 0033984744 scopus 로고    scopus 로고
    • Inflammation, obesity, stress and coronary heart disease: Is interleukin-6 the link?
    • 10657556 10.1016/S0021-9150(99)00463-3 1:CAS:528:DC%2BD3cXosVymtw%3D%3D
    • Yudkin JS, Kumari M, Humphries SE, Mohamed-Ali V (2000) Inflammation, obesity, stress and coronary heart disease: is interleukin-6 the link? Atherosclerosis 148:209-214
    • (2000) Atherosclerosis , vol.148 , pp. 209-214
    • Yudkin, J.S.1    Kumari, M.2    Humphries, S.E.3    Mohamed-Ali, V.4
  • 9
    • 0033804558 scopus 로고    scopus 로고
    • Genetics of inflammation and risk of coronary artery disease: The central role of interleukin 6
    • 10988009 10.1053/euhj.1999.2207 1:STN:280:DC%2BD3M%2Fnt1Wlug%3D%3D
    • Woods A, Brull DJ, Humphries SE et al (2000) Genetics of inflammation and risk of coronary artery disease: the central role of interleukin 6. Eur Heart J 21(19):1574-1583
    • (2000) Eur Heart J , vol.21 , Issue.19 , pp. 1574-1583
    • Woods, A.1    Brull, D.J.2    Humphries, S.E.3
  • 10
    • 69449100622 scopus 로고    scopus 로고
    • PRISMA group. preferred reporting items for systematic reviews and meta-analyses: The PRISMA statement
    • 19622551 10.1136/bmj.b2535
    • Moher D, Liberati A, Tetzlaff J (2009) PRISMA group. preferred reporting items for systematic reviews and meta-analyses: the PRISMA statement. BMJ 339:b2535
    • (2009) BMJ , vol.339 , pp. 2535
    • Moher, D.1    Liberati, A.2    Tetzlaff, J.3
  • 11
    • 0037103172 scopus 로고    scopus 로고
    • Reporting, appraising, and integrating data on genotype prevalence and gene-disease associations
    • 12181099 10.1093/oxfordjournals.aje.a000179
    • Little J, Bradley L, Bray MS, Clyne M, Dorman J, Darrell L et al (2002) Reporting, appraising, and integrating data on genotype prevalence and gene-disease associations. Am J Epidemiol 156:300-310
    • (2002) Am J Epidemiol , vol.156 , pp. 300-310
    • Little, J.1    Bradley, L.2    Bray, M.S.3    Clyne, M.4    Dorman, J.5    Darrell, L.6
  • 12
    • 0032344154 scopus 로고    scopus 로고
    • A comparison of fixed-effects and mixed (random-effects) models for meta-analysis tests of moderator variable effects
    • 10.1037/1082-989X.3.3.354
    • Overton, Randall C (1998) A comparison of fixed-effects and mixed (random-effects) models for meta-analysis tests of moderator variable effects. Psychol Methods 3(3):354-379
    • (1998) Psychol Methods , vol.3 , Issue.3 , pp. 354-379
    • Overton1    Randall, C.2
  • 13
    • 17844365867 scopus 로고    scopus 로고
    • A method for meta-analysis of molecular association studies
    • 15568190 10.1002/sim.2010
    • Thakkinstian A, McElduff P, D'Este C, Duffy D, Attia J (2005) A method for meta-analysis of molecular association studies. Stat Med 24(9):1291-1306
    • (2005) Stat Med , vol.24 , Issue.9 , pp. 1291-1306
    • Thakkinstian, A.1    McElduff, P.2    D'Este, C.3    Duffy, D.4    Attia, J.5
  • 14
    • 33749363062 scopus 로고    scopus 로고
    • Interleukin-1 beta and interleukin-1 receptor antagonist gene polymorphisms and gastric cancer: A meta-analysis
    • 16985030 10.1158/1055-9965.EPI-06-0189 1:CAS:528:DC%2BD28Xps1ynt7o%3D
    • Camargo MC, Mera R, Correa P, Peek RM Jr, Fontham ET, Goodman KJ et al (2006) Interleukin-1 beta and interleukin-1 receptor antagonist gene polymorphisms and gastric cancer: a meta-analysis. Cancer Epidemiol Biomarkers Prev 15(9):1674-1687
    • (2006) Cancer Epidemiol Biomarkers Prev , vol.15 , Issue.9 , pp. 1674-1687
    • Camargo, M.C.1    Mera, R.2    Correa, P.3    Peek Jr., R.M.4    Fontham, E.T.5    Goodman, K.J.6
  • 15
    • 77955785918 scopus 로고    scopus 로고
    • A systematic review and meta-analysis of tumor necrosis factor α-308 polymorphism and Kawasaki disease
    • 20202153 10.1111/j.1442-200X.2010.03105.x
    • Arj-Ong S, Thakkinstian A, McEvoy M, Attia J (2010) A systematic review and meta-analysis of tumor necrosis factor α-308 polymorphism and Kawasaki disease. Pediatr Int 52(4):527-532
    • (2010) Pediatr Int , vol.52 , Issue.4 , pp. 527-532
    • Arj-Ong, S.1    Thakkinstian, A.2    McEvoy, M.3    Attia, J.4
  • 16
    • 0028659004 scopus 로고
    • Operating characteristics of a rank correlation test for publication bias
    • 7786990 10.2307/2533446 1:STN:280:DyaK2Mzgs1GrtQ%3D%3D
    • Begg CB, Mazumdar M (1994) Operating characteristics of a rank correlation test for publication bias. Biometrics 50:1088-1101
    • (1994) Biometrics , vol.50 , pp. 1088-1101
    • Begg, C.B.1    Mazumdar, M.2
  • 17
    • 0030922816 scopus 로고    scopus 로고
    • Bias in meta-analysis detected by a simple, graphical test
    • 9310563 10.1136/bmj.315.7109.629 1:STN:280:DyaK2svls1KjtA%3D%3D
    • Egger M, Davey Smith G, Schneider M, Minder C (1997) Bias in meta-analysis detected by a simple, graphical test. BMJ 315:629-634
    • (1997) BMJ , vol.315 , pp. 629-634
    • Egger, M.1    Davey Smith, G.2    Schneider, M.3    Minder, C.4
  • 18
    • 79960697912 scopus 로고    scopus 로고
    • Genetic polymorphism of interleukin-6 gene and susceptibility to acute myocardial infarction
    • 21512395 10.1097/MCA.0b013e328346b848
    • Vakili H, Ghaderian SM, Akbarzadeh Najar R, Tabatabaei Panah AS, Azargashb E (2011) Genetic polymorphism of interleukin-6 gene and susceptibility to acute myocardial infarction. Coron Artery Dis 22(5):299-305
    • (2011) Coron Artery Dis , vol.22 , Issue.5 , pp. 299-305
    • Vakili, H.1    Ghaderian, S.M.2    Akbarzadeh Najar, R.3    Tabatabaei Panah, A.S.4    Azargashb, E.5
  • 19
    • 79956260118 scopus 로고    scopus 로고
    • Lack of association between IL-1 and IL-6 gene polymorphisms and myocardial infarction in Turkish population
    • 21199393 10.1111/j.1744-313X.2010.00988.x 1:CAS:528:DC%2BC3MXmvFerurg%3D
    • Coker A, Arman A, Soylu O, Tezel T, Yildirim A (2011) Lack of association between IL-1 and IL-6 gene polymorphisms and myocardial infarction in Turkish population. Int J Immunogenet 38(3):201-208
    • (2011) Int J Immunogenet , vol.38 , Issue.3 , pp. 201-208
    • Coker, A.1    Arman, A.2    Soylu, O.3    Tezel, T.4    Yildirim, A.5
  • 20
    • 79951830023 scopus 로고    scopus 로고
    • Genetic and environmental influences on the plasma interleukin-6 concentration in patients with a recent myocardial infarction: A case-control study
    • 21087078 10.1089/jir.2010.0036 1:CAS:528:DC%2BC3MXhvV2qs70%3D
    • Bennermo M, Nordin M, Lundman P, Boqvist S, Held C, Samnegård A et al (2011) Genetic and environmental influences on the plasma interleukin-6 concentration in patients with a recent myocardial infarction: a case-control study. J Interferon Cytokine Res 31(2):259-264
    • (2011) J Interferon Cytokine Res , vol.31 , Issue.2 , pp. 259-264
    • Bennermo, M.1    Nordin, M.2    Lundman, P.3    Boqvist, S.4    Held, C.5    Samnegård, A.6
  • 21
    • 78650345242 scopus 로고    scopus 로고
    • The interleukin 6-572 G > C (rs1800796) polymorphism is associated with the risk of developing acute coronary syndrome
    • 20939703 10.1089/gtmb.2010.0001 1:CAS:528:DC%2BC3cXhsFOjsL3O
    • Fragoso JM, Delgadillo H, Juárez-Cedillo T, Rodríguez- Pérez JM, Vallejo M, Pérez-Méndez O et al (2010) The interleukin 6-572 G > C (rs1800796) polymorphism is associated with the risk of developing acute coronary syndrome. Genet Test Mol Biomarkers 14(6):759-763
    • (2010) Genet Test Mol Biomarkers , vol.14 , Issue.6 , pp. 759-763
    • Fragoso, J.M.1    Delgadillo, H.2    Juárez-Cedillo, T.3    Rodríguez- Pérez, J.M.4    Vallejo, M.5    Pérez-Méndez, O.6
  • 22
    • 77956176283 scopus 로고    scopus 로고
    • TNF-alpha -308G > A and IL-6 -174G > C polymorphisms in Tunisian patients with coronary artery disease
    • 20493832 10.1016/j.clinbiochem.2010.05.005 1:CAS:528:DC%2BC3cXhtVyrtrnM
    • Ghazouani L, Ben Hadj Khalifa S, Abboud N, Ben Hamda K, Ben Khalfallah A, Brahim N et al (2010) TNF-alpha -308G > A and IL-6 -174G > C polymorphisms in Tunisian patients with coronary artery disease. Clin Biochem 43(13-14):1085-1089
    • (2010) Clin Biochem , vol.43 , Issue.13-14 , pp. 1085-1089
    • Ghazouani, L.1    Ben Hadj Khalifa, S.2    Abboud, N.3    Ben Hamda, K.4    Ben Khalfallah, A.5    Brahim, N.6
  • 23
    • 77952585414 scopus 로고    scopus 로고
    • Interleukin-1 beta and interleukin-6 gene polymorphism associations with angiographically assessed coronary artery disease in Brazilians
    • 20206549 10.1016/j.cyto.2010.02.012 1:CAS:528:DC%2BC3cXlvVegtL0%3D
    • Rios DL, Cerqueira CC, Bonfim-Silva R, Araújo LJ, Pereira JF, Gadelha SR et al (2010) Interleukin-1 beta and interleukin-6 gene polymorphism associations with angiographically assessed coronary artery disease in Brazilians. Cytokine 50(3):292-296
    • (2010) Cytokine , vol.50 , Issue.3 , pp. 292-296
    • Rios, D.L.1    Cerqueira, C.C.2    Bonfim-Silva, R.3    Araújo, L.J.4    Pereira, J.F.5    Gadelha, S.R.6
  • 24
    • 77649251844 scopus 로고    scopus 로고
    • Association between the interleukin-6 gene -572G/C and -597G/A polymorphisms and coronary heart disease in the Han Chinese
    • 20190679 1:CAS:528:DC%2BC3cXksl2gtr0%3D
    • Jia X, Tian Y, Wang Y, Deng X, Dong Z, Scafa N et al (2010) Association between the interleukin-6 gene -572G/C and -597G/A polymorphisms and coronary heart disease in the Han Chinese. Med Sci Monit 16(3):CR103-CR108
    • (2010) Med Sci Monit , vol.16 , Issue.3
    • Jia, X.1    Tian, Y.2    Wang, Y.3    Deng, X.4    Dong, Z.5    Scafa, N.6
  • 25
    • 58549101885 scopus 로고    scopus 로고
    • Carrier-state of two or three polymorphic variants of MTHFR, IL-6 and ICAM1 genes increases the risk of coronary artery disease
    • 19169973
    • Sarecka-Hujar B, Zak I, Krauze J (2008) Carrier-state of two or three polymorphic variants of MTHFR, IL-6 and ICAM1 genes increases the risk of coronary artery disease. Kardiol Pol 66(12):1269-1277
    • (2008) Kardiol Pol , vol.66 , Issue.12 , pp. 1269-1277
    • Sarecka-Hujar, B.1    Zak, I.2    Krauze, J.3
  • 26
    • 60649121402 scopus 로고    scopus 로고
    • Association between inflammatory gene polymorphisms and coronary artery disease in an Indian population
    • 18157711 10.1007/s11239-007-0184-8 1:CAS:528:DC%2BD1MXhvV2jtLo%3D
    • Banerjee I, Pandey U, Hasan OM, Parihar R, Tripathi V, Ganesh S (2009) Association between inflammatory gene polymorphisms and coronary artery disease in an Indian population. J Thromb Thrombolysis 27(1):88-94
    • (2009) J Thromb Thrombolysis , vol.27 , Issue.1 , pp. 88-94
    • Banerjee, I.1    Pandey, U.2    Hasan, O.M.3    Parihar, R.4    Tripathi, V.5    Ganesh, S.6
  • 27
    • 35649024964 scopus 로고    scopus 로고
    • Interleukin-6 -597G/A and -572C/G polymorphisms and risk of coronary heart disease
    • 16842669 1:CAS:528:DC%2BD28XosVSmtbc%3D [Chinese]
    • Fu HX, Li GS, Li Y, Xu JL, Zhang JY (2006) Interleukin-6 -597G/A and -572C/G polymorphisms and risk of coronary heart disease. Zhonghua Xin Xue Guan Bing Za Zhi 34(6):519-522 [Chinese]
    • (2006) Zhonghua Xin Xue Guan Bing Za Zhi , vol.34 , Issue.6 , pp. 519-522
    • Fu, H.X.1    Li, G.S.2    Li, Y.3    Xu, J.L.4    Zhang, J.Y.5
  • 28
    • 33646556397 scopus 로고    scopus 로고
    • Relationship between interleukin-6 gene polymorphism and coronary heart disease and its effect on plasma lipid levels
    • 16647016 1:CAS:528:DC%2BD28XlsFKhsL8%3D [Chinese]
    • Wei YS, Lan Y, Liu YG, Tang RG, Lan JS (2006) Relationship between interleukin-6 gene polymorphism and coronary heart disease and its effect on plasma lipid levels. Zhongguo Wei Zhong Bing Ji Jiu Yi Xue 18(4):233-236 [Chinese]
    • (2006) Zhongguo Wei Zhong Bing Ji Jiu Yi Xue , vol.18 , Issue.4 , pp. 233-236
    • Wei, Y.S.1    Lan, Y.2    Liu, Y.G.3    Tang, R.G.4    Lan, J.S.5
  • 29
    • 28444457805 scopus 로고    scopus 로고
    • Interleukin-6 gene polymorphism is an age-dependent risk factor for myocardial infarction in men
    • 16313298 10.1111/j.1744-313X.2005.00537.x 1:CAS:528:DC%2BD2MXhtlWqs77N
    • Chiappelli M, Tampieri C, Tumini E, Porcellini E, Caldarera CM, Nanni S et al (2005) Interleukin-6 gene polymorphism is an age-dependent risk factor for myocardial infarction in men. Int J Immunogenet 32(6):349-353
    • (2005) Int J Immunogenet , vol.32 , Issue.6 , pp. 349-353
    • Chiappelli, M.1    Tampieri, C.2    Tumini, E.3    Porcellini, E.4    Caldarera, C.M.5    Nanni, S.6
  • 30
    • 27944432628 scopus 로고    scopus 로고
    • Interaction between inflammation-related gene polymorphisms and cigarette smoking on the risk of myocardial infarction in the physician's health study
    • 16184405 10.1007/s00439-005-0052-6
    • Rosner SA, Ridker PM, Zee RY, Cook NR (2005) Interaction between inflammation-related gene polymorphisms and cigarette smoking on the risk of myocardial infarction in the physician's health study. Hum Genet 118(2):287-294
    • (2005) Hum Genet , vol.118 , Issue.2 , pp. 287-294
    • Rosner, S.A.1    Ridker, P.M.2    Zee, R.Y.3    Cook, N.R.4
  • 31
    • 20844445291 scopus 로고    scopus 로고
    • Effect of Interleukin-6 promoter polymorphisms in survivors of myocardial infarction and matched controls in the North and South of Europe
    • 1:CAS:528:DC%2BD2cXhtVegs7zK
    • Kelberman D, Hawe E, Luong LA, Mohamed-Ali V, Lundman P, Tornvall P et al (2004) Effect of Interleukin-6 promoter polymorphisms in survivors of myocardial infarction and matched controls in the North and South of Europe. The HIFMECH Study. Thromb Haemost 92(5):1122-1128
    • (2004) The HIFMECH Study. Thromb Haemost , vol.92 , Issue.5 , pp. 1122-1128
    • Kelberman, D.1    Hawe, E.2    Luong, L.A.3    Mohamed-Ali, V.4    Lundman, P.5    Tornvall, P.6
  • 32
    • 4644262151 scopus 로고    scopus 로고
    • No association of interleukin-6 gene polymorphism (-174 G/C) with myocardial infarction or traditional cardiovascular risk factors
    • 15458685 10.1016/j.ijcard.2003.07.038
    • Lieb W, Pavlik R, Erdmann J, Mayer B, Holmer SR, Fischer M et al (2004) No association of interleukin-6 gene polymorphism (-174 G/C) with myocardial infarction or traditional cardiovascular risk factors. Int J Cardiol 97(2):205-212
    • (2004) Int J Cardiol , vol.97 , Issue.2 , pp. 205-212
    • Lieb, W.1    Pavlik, R.2    Erdmann, J.3    Mayer, B.4    Holmer, S.R.5    Fischer, M.6
  • 33
    • 4344617212 scopus 로고    scopus 로고
    • The concomitant presence of polymorphic alleles of interleukin-1 beta, interleukin-6 and apolipoprotein e is associated with an increased risk of myocardial infarction in elderly men. Results from a pilot study
    • 15336915 1:CAS:528:DC%2BD2cXntV2msrg%3D
    • Licastro F, Chiappelli M, Caldarera CM, Tampieri C, Nanni S, Gallina M et al (2004) The concomitant presence of polymorphic alleles of interleukin-1 beta, interleukin-6 and apolipoprotein E is associated with an increased risk of myocardial infarction in elderly men. Results from a pilot study. Mech Ageing Dev 125(8):575-579
    • (2004) Mech Ageing Dev , vol.125 , Issue.8 , pp. 575-579
    • Licastro, F.1    Chiappelli, M.2    Caldarera, C.M.3    Tampieri, C.4    Nanni, S.5    Gallina, M.6
  • 34
    • 0036373824 scopus 로고    scopus 로고
    • The interleukin-6 G(-174)C promoter polymorphism in the LURIC cohort: No association with plasma interleukin-6, coronary artery disease, and myocardial infarction
    • 12185451 10.1007/s00109-002-0354-2 1:CAS:528:DC%2BD38Xns1ags7g%3D
    • Nauck M, Winkelmann BR, Hoffmann MM, Böhm BO, Wieland H, März W (2002) The interleukin-6 G(-174)C promoter polymorphism in the LURIC cohort: no association with plasma interleukin-6, coronary artery disease, and myocardial infarction. J Mol Med Berl 80(8):507-513
    • (2002) J Mol Med Berl , vol.80 , Issue.8 , pp. 507-513
    • Nauck, M.1    Winkelmann, B.R.2    Hoffmann, M.M.3    Böhm, B.O.4    Wieland, H.5    März, W.6
  • 35
    • 0035661847 scopus 로고    scopus 로고
    • The interleukin-6 -174 G/C promoter polymorphism is associated with risk of coronary heart disease and systolic blood pressure in healthy men
    • 11728144 10.1053/euhj.2001.2678 1:CAS:528:DC%2BD38XltVansQ%3D%3D
    • Humphries SE, Luong LA, Ogg MS, Hawe E, Miller GJ (2001) The interleukin-6 -174 G/C promoter polymorphism is associated with risk of coronary heart disease and systolic blood pressure in healthy men. Eur Heart J 22(24):2243-2252
    • (2001) Eur Heart J , vol.22 , Issue.24 , pp. 2243-2252
    • Humphries, S.E.1    Luong, L.A.2    Ogg, M.S.3    Hawe, E.4    Miller, G.J.5
  • 36
    • 0034945885 scopus 로고    scopus 로고
    • Interleukin-6 gene polymorphisms and susceptibility to myocardial infarction: The ECTIM study. Etude Cas-Témoin de l'Infarctus du Myocarde
    • 11485024 10.1007/s001090100209 1:CAS:528:DC%2BD3MXlslWgt7c%3D
    • Georges JL, Loukaci V, Poirier O, Evans A, Luc G, Arveiler D et al (2001) Interleukin-6 gene polymorphisms and susceptibility to myocardial infarction: the ECTIM study. Etude Cas-Témoin de l'Infarctus du Myocarde. J Mol Med Berl 79(5-6):300-305
    • (2001) J Mol Med Berl , vol.79 , Issue.5-6 , pp. 300-305
    • Georges, J.L.1    Loukaci, V.2    Poirier, O.3    Evans, A.4    Luc, G.5    Arveiler, D.6
  • 37
    • 79952604371 scopus 로고    scopus 로고
    • Coronary heart disease and chronic periodontitis: Is polymorphism of interleukin-6 gene the common risk factor in a Chinese population?
    • 20860764 10.1111/j.1601-0825.2010.01736.x 1:STN:280: DC%2BC3M3lvFagtw%3D%3D
    • Fan WH, Liu DL, Xiao LM, Xie CJ, Sun SY, Zhang JC (2011) Coronary heart disease and chronic periodontitis: is polymorphism of interleukin-6 gene the common risk factor in a Chinese population? Oral Dis 17(3):270-276
    • (2011) Oral Dis , vol.17 , Issue.3 , pp. 270-276
    • Fan, W.H.1    Liu, D.L.2    Xiao, L.M.3    Xie, C.J.4    Sun, S.Y.5    Zhang, J.C.6
  • 38
    • 72549115425 scopus 로고    scopus 로고
    • Interaction between fibrinogen and IL-6 genetic variants and associations with cardiovascular disease risk in the Cardiovascular Health Study
    • 20059469 10.1111/j.1469-1809.2009.00551.x 1:CAS:528:DC%2BC3cXht1Omt7Y%3D
    • Carty CL, Heagerty P, Heckbert SR, Jarvik GP, Lange LA, Cushman M et al (2010) Interaction between fibrinogen and IL-6 genetic variants and associations with cardiovascular disease risk in the Cardiovascular Health Study. Ann Hum Genet 74(1):1-10
    • (2010) Ann Hum Genet , vol.74 , Issue.1 , pp. 1-10
    • Carty, C.L.1    Heagerty, P.2    Heckbert, S.R.3    Jarvik, G.P.4    Lange, L.A.5    Cushman, M.6
  • 39
    • 69249154579 scopus 로고    scopus 로고
    • Influence of interleukin-6 G-174C gene polymorphism on coronary artery disease, cardiovascular complications and mortality in dialysis patients
    • 19349293 10.1093/ndt/gfp141 1:CAS:528:DC%2BD1MXhtVGqu7vO
    • Aker S, Bantis C, Reis P, Kuhr N, Schwandt C, Grabensee B et al (2009) Influence of interleukin-6 G-174C gene polymorphism on coronary artery disease, cardiovascular complications and mortality in dialysis patients. Nephrol Dial Transplant 24(9):2847-2851
    • (2009) Nephrol Dial Transplant , vol.24 , Issue.9 , pp. 2847-2851
    • Aker, S.1    Bantis, C.2    Reis, P.3    Kuhr, N.4    Schwandt, C.5    Grabensee, B.6
  • 40
    • 58149098228 scopus 로고    scopus 로고
    • The additive contribution from inflammatory genetic markers on the severity of cardiovascular disease
    • 19140875 10.1111/j.1365-3083.2008.02187.x 1:CAS:528:DC%2BD1MXhvVGnu7o%3D
    • Berg KK, Madsen HO, Garred P, Wiseth R, Gunnes S, Videm V (2009) The additive contribution from inflammatory genetic markers on the severity of cardiovascular disease. Scand J Immunol 69(1):36-42
    • (2009) Scand J Immunol , vol.69 , Issue.1 , pp. 36-42
    • Berg, K.K.1    Madsen, H.O.2    Garred, P.3    Wiseth, R.4    Gunnes, S.5    Videm, V.6
  • 41
    • 41849119426 scopus 로고    scopus 로고
    • Synergistic effects of the polymorphisms in the PAI-1 and IL-6 genes with smoking in determining their associated risk with coronary artery disease
    • 18307986 10.1016/j.clinbiochem.2008.01.028 1:CAS:528:DC%2BD1cXks12it7o%3D
    • Sarecka B, Zak I, Krauze J (2008) Synergistic effects of the polymorphisms in the PAI-1 and IL-6 genes with smoking in determining their associated risk with coronary artery disease. Clin Biochem 41(7-8):467-473
    • (2008) Clin Biochem , vol.41 , Issue.7-8 , pp. 467-473
    • Sarecka, B.1    Zak, I.2    Krauze, J.3
  • 42
    • 40949089295 scopus 로고    scopus 로고
    • Variation in inflammation-related genes and risk of incident nonfatal myocardial infarction or ischemic stroke
    • 10.1016/j.atherosclerosis.2007.09.031
    • Bis JC, Heckbert SR, Smith NL et al (2000) Variation in inflammation-related genes and risk of incident nonfatal myocardial infarction or ischemic stroke. Atherosclerosis 198(1):166-173
    • (2000) Atherosclerosis , vol.198 , Issue.1 , pp. 166-173
    • Bis, J.C.1    Heckbert, S.R.2    Smith, N.L.3
  • 43
    • 33846424939 scopus 로고    scopus 로고
    • Genetic variation in the interleukin-6 gene in relation to risk and outcomes in acute coronary syndrome
    • 16782174 10.1016/j.thromres.2006.05.001
    • Mälarstig A, Wallentin L, Siegbahn A (2007) Genetic variation in the interleukin-6 gene in relation to risk and outcomes in acute coronary syndrome. Thromb Res 119(4):467-473
    • (2007) Thromb Res , vol.119 , Issue.4 , pp. 467-473
    • Mälarstig, A.1    Wallentin, L.2    Siegbahn, A.3
  • 44
    • 33644820475 scopus 로고    scopus 로고
    • Interleukin 6-174 g/c promoter polymorphism and risk of coronary heart disease: Results from the rotterdam study and a meta-analysis
    • 16269662 10.1161/01.ATV.0000194099.65024.17 1:CAS:528:DC%2BD2MXhtlagt7jP
    • Sie MP, Sayed-Tabatabaei FA, Oei HH, Uitterlinden AG, Pols HA, Hofman A et al (2006) Interleukin 6-174 g/c promoter polymorphism and risk of coronary heart disease: results from the rotterdam study and a meta-analysis. Arterioscler Thromb Vasc Biol 26(1):212-217
    • (2006) Arterioscler Thromb Vasc Biol , vol.26 , Issue.1 , pp. 212-217
    • Sie, M.P.1    Sayed-Tabatabaei, F.A.2    Oei, H.H.3    Uitterlinden, A.G.4    Pols, H.A.5    Hofman, A.6
  • 45
    • 26044482278 scopus 로고    scopus 로고
    • Additive effects of the chemokine receptor 2, vitamin D receptor, interleukin-6 polymorphisms and cardiovascular risk factors on the prevalence of myocardial infarction in patients below 65 years
    • 16207551 10.1016/j.ijcard.2005.03.004
    • Ortlepp JR, Krantz C, Kimmel M, von Korff A, Vesper K, Schmitz F et al (2005) Additive effects of the chemokine receptor 2, vitamin D receptor, interleukin-6 polymorphisms and cardiovascular risk factors on the prevalence of myocardial infarction in patients below 65 years. Int J Cardiol 105(1):90-95
    • (2005) Int J Cardiol , vol.105 , Issue.1 , pp. 90-95
    • Ortlepp, J.R.1    Krantz, C.2    Kimmel, M.3    Von Korff, A.4    Vesper, K.5    Schmitz, F.6
  • 46
    • 23644460480 scopus 로고    scopus 로고
    • The interleukin-6 -174 G > C promoter polymorphism is associated with a higher risk of death after an acute coronary syndrome in male elderly patients
    • 16098388 10.1016/j.ijcard.2004.08.064
    • Antonicelli R, Olivieri F, Bonafè M, Cavallone L, Spazzafumo L, Marchegiani F et al (2005) The interleukin-6 -174 G > C promoter polymorphism is associated with a higher risk of death after an acute coronary syndrome in male elderly patients. Int J Cardiol 103(3):266-271
    • (2005) Int J Cardiol , vol.103 , Issue.3 , pp. 266-271
    • Antonicelli, R.1    Olivieri, F.2    Bonafè, M.3    Cavallone, L.4    Spazzafumo, L.5    Marchegiani, F.6
  • 47
    • 20144365771 scopus 로고    scopus 로고
    • Interaction between the C-260T polymorphism of the CD14 gene and the plasma IL-6 concentration on the risk of myocardial infarction: The HIFMECH study
    • 15777548 10.1016/j.atherosclerosis.2004.10.014 1:CAS:528: DC%2BD2MXitlCju78%3D
    • Morange PE, Saut N, Alessi MC, Frere C, Hawe E, Yudkin JS et al (2005) Interaction between the C-260T polymorphism of the CD14 gene and the plasma IL-6 concentration on the risk of myocardial infarction: the HIFMECH study. Atherosclerosis 179(2):317-323
    • (2005) Atherosclerosis , vol.179 , Issue.2 , pp. 317-323
    • Morange, P.E.1    Saut, N.2    Alessi, M.C.3    Frere, C.4    Hawe, E.5    Yudkin, J.S.6
  • 48
    • 4744372179 scopus 로고    scopus 로고
    • C-reactive protein levels and common polymorphisms of the interleukin-1 gene cluster and interleukin-6 gene in patients with coronary heart disease
    • 15379752 10.1111/j.1365-2370.2004.00476.x 1:CAS:528:DC%2BD2cXptlGhs7w%3D
    • Latkovskis G, Licis N, Kalnins U (2004) C-reactive protein levels and common polymorphisms of the interleukin-1 gene cluster and interleukin-6 gene in patients with coronary heart disease. Eur J Immunogenet 31(5):207-213
    • (2004) Eur J Immunogenet , vol.31 , Issue.5 , pp. 207-213
    • Latkovskis, G.1    Licis, N.2    Kalnins, U.3
  • 49
    • 3042795368 scopus 로고    scopus 로고
    • Genetic risk and gene-environment interaction in coronary artery spasm in Japanese men and women
    • 15172469 10.1016/j.ehj.2004.02.020
    • Murase Y, Yamada Y, Hirashiki A, Ichihara S, Kanda H, Watarai M et al (2004) Genetic risk and gene-environment interaction in coronary artery spasm in Japanese men and women. Eur Heart J 25(11):970-977
    • (2004) Eur Heart J , vol.25 , Issue.11 , pp. 970-977
    • Murase, Y.1    Yamada, Y.2    Hirashiki, A.3    Ichihara, S.4    Kanda, H.5    Watarai, M.6
  • 50
    • 2342564921 scopus 로고    scopus 로고
    • Prognostic value of plasma interleukin-6 concentrations and the -174 G > C and -572 G > C promoter polymorphisms of the interleukin-6 gene in patients with acute myocardial infarction treated with thrombolysis
    • 15135265 10.1016/j.atherosclerosis.2004.01.019 1:CAS:528: DC%2BD2cXjvVGqtLw%3D
    • Bennermo M, Held C, Green F, Strandberg LE, Ericsson CG, Hansson LO et al (2004) Prognostic value of plasma interleukin-6 concentrations and the -174 G > C and -572 G > C promoter polymorphisms of the interleukin-6 gene in patients with acute myocardial infarction treated with thrombolysis. Atherosclerosis 174(1):157-163
    • (2004) Atherosclerosis , vol.174 , Issue.1 , pp. 157-163
    • Bennermo, M.1    Held, C.2    Green, F.3    Strandberg, L.E.4    Ericsson, C.G.5    Hansson, L.O.6
  • 51
    • 0035573649 scopus 로고    scopus 로고
    • Interleukin-6 gene -174G > C and -572G > C promoter polymorphisms are strong predictors of plasma interleukin-6 levels after coronary artery bypass surgery
    • 11557672 10.1161/hq0901.094280 1:CAS:528:DC%2BD3MXntVGku7o%3D
    • Brull DJ, Montgomery HE, Sanders J, Dhamrait S, Luong L, Rumley A et al (2001) Interleukin-6 gene -174G > C and -572G > C promoter polymorphisms are strong predictors of plasma interleukin-6 levels after coronary artery bypass surgery. Arterioscler Thromb Vasc Biol 21:1458-1463
    • (2001) Arterioscler Thromb Vasc Biol , vol.21 , pp. 1458-1463
    • Brull, D.J.1    Montgomery, H.E.2    Sanders, J.3    Dhamrait, S.4    Luong, L.5    Rumley, A.6
  • 52
    • 0036920138 scopus 로고    scopus 로고
    • In the elderly, interleukin-6 plasma levels and the -174G > C polymorphism are associated with the development of cardiovascular disease
    • 12482836 10.1161/01.ATV.0000040224.49362.60 1:CAS:528: DC%2BD38Xpt1Chsr4%3D
    • Jenny NS, Tracy RP, Ogg MS, le Luong A, Kuller LH, Arnold AM et al (2002) In the elderly, interleukin-6 plasma levels and the -174G > C polymorphism are associated with the development of cardiovascular disease. Arterioscler Thromb Vasc Biol 22(12):2066-2071
    • (2002) Arterioscler Thromb Vasc Biol , vol.22 , Issue.12 , pp. 2066-2071
    • Jenny, N.S.1    Tracy, R.P.2    Ogg, M.S.3    Le Luong, A.4    Kuller, L.H.5    Arnold, A.M.6
  • 53
    • 84862777716 scopus 로고    scopus 로고
    • Association of interleukin-6 circulating levels with coronary artery disease: A meta-analysis implementing Mendelian randomization approach
    • 22261689 10.1016/j.ijcard.2011.12.098
    • Niu W, Liu Y, Qi Y, Wu Z, Zhu D, Jin W (2012) Association of interleukin-6 circulating levels with coronary artery disease: a meta-analysis implementing Mendelian randomization approach. Int J Cardiol 157(2):243-252
    • (2012) Int J Cardiol , vol.157 , Issue.2 , pp. 243-252
    • Niu, W.1    Liu, Y.2    Qi, Y.3    Wu, Z.4    Zhu, D.5    Jin, W.6


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.