Relationship between interleukin - 6 gene polymorphism and coronary heart disease and its effect on plasma lipid levels

Chinese Critical Care Medicine

Volumn 18, Issue 4, 2006, Pages 233-236

  Wei, Ye Sheng ^a   Lan, Yan ^a   Liu, Yun Guang ^a   Tang, Ren Guang ^a   Lan, Jing Sheng ^a  

^a Department of Clinical Laboratory Center   (China)

Author keywords

Coronary heart disease; Gene polymorphism; Interleukin 6; Plasma lipid

Indexed keywords

CHOLESTEROL; CYTOSINE; GUANINE; INTERLEUKIN 6; LIPID; LIPOPROTEIN; LOW DENSITY LIPOPROTEIN CHOLESTEROL;

ALLELE; ARTICLE; CHOLESTEROL BLOOD LEVEL; CONFIDENCE INTERVAL; CONTROLLED STUDY; GENETIC MARKER; GENETIC POLYMORPHISM; GENOTYPE; HETEROZYGOTE; HUMAN; ISCHEMIC HEART DISEASE; LIPID BLOOD LEVEL; LIPOPROTEIN BLOOD LEVEL; MAJOR CLINICAL STUDY; POLYMERASE CHAIN REACTION; PROMOTER REGION; RESTRICTION FRAGMENT LENGTH POLYMORPHISM; RISK ASSESSMENT; STATISTICAL SIGNIFICANCE; TRIACYLGLYCEROL BLOOD LEVEL;

AGED; AGED, 80 AND OVER; CORONARY DISEASE; FEMALE; GENE FREQUENCY; GENOTYPE; HUMANS; INTERLEUKIN-6; LIPIDS; MALE; MIDDLE AGED; POLYMORPHISM, GENETIC; POLYMORPHISM, RESTRICTION FRAGMENT LENGTH;

EID: 33646556397     PISSN: 10030603     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (12)

1. Zhang Y, Hayes A, Pritchard A, et al. Interleukin-6 promoter polymorphism; risk and pathology of Alzheimer's disease [J]. Neurosci Lett,2004,362:99-102.
2. Nishimura M,Matsuoka M,Maeda M,et al. Association between interleukin-6 gene polymorphism and human T-cell leukemia virus type I associated myelopathy[J]. Hum Immunol,2002,63: 696-700.
3. Ota N,Nakajima T,Nakazawa I, et al. A nucleotide variant in the promoter region of the interleukin-6 gene associated with decreased bone mineral density [J]. J Hum Genet, 2001, 46: 267-272.
4. Georges J L, Loukaci V, Poirier O, et al. Interleukin-6 gene polymorphisms and susceptibility to myocardial infarction: the ECTIM study. Etude Cas-Temoin de L'Infarctus du Myocarde [J]. J Mol Med,2001,79:300-305.
5. Brull D J, Montgomery H E, Sanders J, et al. Interleukin-6 gene-174g>c and - 572g>c promoter polymorphisms are strong predictors of plasma interleukin-6 levels after coronary artery bypass surgery[J]. Arterioscler Thromb Vasc Biol,2001, 21:1458-1463.
6. Kitamura A, Hasegawa G, Obayashi H, et al. Interleukin-6 polymorphism (- 634C/G) in the promotor region and the progression of diabetic nephropathy in type 2 diabetes[J]. Diabet Med,2002,19:1000-1005.
7. Chinese source. 2005,28:173-177.
8. Libby P,Ridker P M,Maseri A. Inflammation and atherosclerosis [J]. Circulation, 2002,105:1135-1143.
9. Chinese source. 2004,16:536-539.
10. Ikeda U, Ito T, Shimada K, et al. Interleukin-6 and acute coronary syndrome[J]. Clin Cardiol,2001,24:701-704.
11. Mendall M A, Patel P, Asante M, et al. Relation of serum cytokine concentrations to cardiovascular risk factors and coronary heart disease[J]. Heart, 1997,78:273-277
12. Ikonomidis I, Andreotti F, Economou E, et al. Increased proinflammatory cytokines in patients with chronic stable angina and their reduction by aspirin [J]. Circulation, 1999,100:793-798.