메뉴 건너뛰기




Volumn 157, Issue 2, 2012, Pages 243-252

Association of interleukin-6 circulating levels with coronary artery disease: A meta-analysis implementing mendelian randomization approach

Author keywords

Coronary artery disease; Interleukin 6; Mendelian randomization; Meta analysis; Polymorphism

Indexed keywords

INTERLEUKIN 6;

EID: 84862777716     PISSN: 01675273     EISSN: 18741754     Source Type: Journal    
DOI: 10.1016/j.ijcard.2011.12.098     Document Type: Article
Times cited : (43)

References (50)
  • 1
    • 51549096161 scopus 로고    scopus 로고
    • The genetic basis of coronary artery disease: From candidate genes to whole genome analysis
    • M. Franchini, F. Peyvandi, and P.M. Mannucci The genetic basis of coronary artery disease: from candidate genes to whole genome analysis Trends Cardiovasc Med. 18 2008 157 162
    • (2008) Trends Cardiovasc Med. , vol.18 , pp. 157-162
    • Franchini, M.1    Peyvandi, F.2    Mannucci, P.M.3
  • 2
    • 64649094131 scopus 로고    scopus 로고
    • DNA variants, plasma levels and variability of interleukin-6 in myocardial infarction survivors: Results from the AIRGENE study
    • P. Ljungman, T. Bellander, F. Nyberg, E. Lampa, B. Jacquemin, and M. Kolz DNA variants, plasma levels and variability of interleukin-6 in myocardial infarction survivors: results from the AIRGENE study Thromb Res. 124 2009 57 64
    • (2009) Thromb Res. , vol.124 , pp. 57-64
    • Ljungman, P.1    Bellander, T.2    Nyberg, F.3    Lampa, E.4    Jacquemin, B.5    Kolz, M.6
  • 3
    • 33747885499 scopus 로고    scopus 로고
    • Coronary artery calcification and myocardial perfusion in asymptomatic adults: The MESA (Multi-Ethnic Study of Atherosclerosis)
    • L. Wang, M. Jerosch-Herold, D.R. Jacobs Jr., E. Shahar, R. Detrano, and A.R. Folsom Coronary artery calcification and myocardial perfusion in asymptomatic adults: the MESA (Multi-Ethnic Study of Atherosclerosis) J Am Coll Cardiol. 48 2006 1018 1026
    • (2006) J Am Coll Cardiol. , vol.48 , pp. 1018-1026
    • Wang, L.1    Jerosch-Herold, M.2    Jacobs, Jr.D.R.3    Shahar, E.4    Detrano, R.5    Folsom, A.R.6
  • 4
    • 0033552883 scopus 로고    scopus 로고
    • Atherosclerosis - An inflammatory disease
    • R. Ross Atherosclerosis - an inflammatory disease N Engl J Med. 340 1999 115 126
    • (1999) N Engl J Med. , vol.340 , pp. 115-126
    • Ross, R.1
  • 7
    • 20844449693 scopus 로고    scopus 로고
    • Impact of interleukin-6 on plaque development and morphology in experimental atherosclerosis
    • B. Schieffer, T. Selle, A. Hilfiker, D. Hilfiker-Kleiner, K. Grote, and U.J. Tietge Impact of interleukin-6 on plaque development and morphology in experimental atherosclerosis Circulation. 110 2004 3493 3500
    • (2004) Circulation. , vol.110 , pp. 3493-3500
    • Schieffer, B.1    Selle, T.2    Hilfiker, A.3    Hilfiker-Kleiner, D.4    Grote, K.5    Tietge, U.J.6
  • 8
    • 0028261395 scopus 로고
    • Interleukin 6 gene transcripts are expressed in human atherosclerotic lesions
    • Y. Seino, U. Ikeda, M. Ikeda, K. Yamamoto, Y. Misawa, and T. Hasegawa Interleukin 6 gene transcripts are expressed in human atherosclerotic lesions Cytokine. 6 1994 87 91
    • (1994) Cytokine. , vol.6 , pp. 87-91
    • Seino, Y.1    Ikeda, U.2    Ikeda, M.3    Yamamoto, K.4    Misawa, Y.5    Hasegawa, T.6
  • 9
    • 33751191631 scopus 로고    scopus 로고
    • Increased concentrations of C-reactive protein and IL-6 but not IL-18 are independently associated with incident coronary events in middle-aged men and women: Results from the MONICA/KORA Augsburg case-cohort study, 1984-2002
    • W. Koenig, N. Khuseyinova, J. Baumert, B. Thorand, H. Loewel, and L. Chambless Increased concentrations of C-reactive protein and IL-6 but not IL-18 are independently associated with incident coronary events in middle-aged men and women: results from the MONICA/KORA Augsburg case-cohort study, 1984-2002 Arterioscler Thromb Vasc Biol. 26 2006 2745 2751
    • (2006) Arterioscler Thromb Vasc Biol. , vol.26 , pp. 2745-2751
    • Koenig, W.1    Khuseyinova, N.2    Baumert, J.3    Thorand, B.4    Loewel, H.5    Chambless, L.6
  • 10
    • 0034681920 scopus 로고    scopus 로고
    • Plasma concentration of interleukin-6 and the risk of future myocardial infarction among apparently healthy men
    • P.M. Ridker, N. Rifai, M.J. Stampfer, and C.H. Hennekens Plasma concentration of interleukin-6 and the risk of future myocardial infarction among apparently healthy men Circulation. 101 2000 1767 1772
    • (2000) Circulation. , vol.101 , pp. 1767-1772
    • Ridker, P.M.1    Rifai, N.2    Stampfer, M.J.3    Hennekens, C.H.4
  • 11
    • 77955296455 scopus 로고    scopus 로고
    • The interaction between coagulation factor 2 receptor and interleukin 6 haplotypes increases the risk of myocardial infarction in men
    • B. Gigante, A.M. Bennet, K. Leander, M. Vikstrom, and U. de Faire The interaction between coagulation factor 2 receptor and interleukin 6 haplotypes increases the risk of myocardial infarction in men PLoS One. 5 2010 e11300
    • (2010) PLoS One. , vol.5 , pp. 11300
    • Gigante, B.1    Bennet, A.M.2    Leander, K.3    Vikstrom, M.4    De Faire, U.5
  • 12
    • 79952154996 scopus 로고    scopus 로고
    • Association of alpha-adducin and G-protein beta3 genetic polymorphisms with hypertension: A meta-analysis of Chinese populations
    • W. Niu, and Y. Qi Association of alpha-adducin and G-protein beta3 genetic polymorphisms with hypertension: a meta-analysis of Chinese populations PLoS One. 6 2011 e17052
    • (2011) PLoS One. , vol.6 , pp. 17052
    • Niu, W.1    Qi, Y.2
  • 13
    • 76749092615 scopus 로고    scopus 로고
    • Synopsis and data synthesis of genetic association studies in hypertension for the adrenergic receptor family genes: The CUMAGAS-HYPERT database
    • G.D. Kitsios, and E. Zintzaras Synopsis and data synthesis of genetic association studies in hypertension for the adrenergic receptor family genes: the CUMAGAS-HYPERT database Am J Hypertens. 23 2010 305 313
    • (2010) Am J Hypertens. , vol.23 , pp. 305-313
    • Kitsios, G.D.1    Zintzaras, E.2
  • 14
    • 84880230242 scopus 로고    scopus 로고
    • Association between C reactive protein and coronary heart disease: Mendelian randomisation analysis based on individual participant data
    • F. Wensley, P. Gao, S. Burgess, S. Kaptoge, E. Di Angelantonio, and T. Shah Association between C reactive protein and coronary heart disease: mendelian randomisation analysis based on individual participant data BMJ. 342 2011 d548
    • (2011) BMJ. , vol.342 , pp. 548
    • Wensley, F.1    Gao, P.2    Burgess, S.3    Kaptoge, S.4    Di Angelantonio, E.5    Shah, T.6
  • 15
    • 26244442855 scopus 로고    scopus 로고
    • Does elevated plasma fibrinogen increase the risk of coronary heart disease? Evidence from a meta-analysis of genetic association studies
    • G.D. Smith, R. Harbord, J. Milton, S. Ebrahim, and J.A. Sterne Does elevated plasma fibrinogen increase the risk of coronary heart disease? Evidence from a meta-analysis of genetic association studies Arterioscler Thromb Vasc Biol. 25 2005 2228 2233
    • (2005) Arterioscler Thromb Vasc Biol. , vol.25 , pp. 2228-2233
    • Smith, G.D.1    Harbord, R.2    Milton, J.3    Ebrahim, S.4    Sterne, J.A.5
  • 16
    • 0142136688 scopus 로고    scopus 로고
    • How meta-analysis increases statistical power
    • L.D. Cohn, and B.J. Becker How meta-analysis increases statistical power Psychol Methods. 8 2003 243 253
    • (2003) Psychol Methods. , vol.8 , pp. 243-253
    • Cohn, L.D.1    Becker, B.J.2
  • 17
    • 0037098199 scopus 로고    scopus 로고
    • Quantifying heterogeneity in a meta-analysis
    • J.P. Higgins, and S.G. Thompson Quantifying heterogeneity in a meta-analysis Stat Med. 21 2002 1539 1558
    • (2002) Stat Med. , vol.21 , pp. 1539-1558
    • Higgins, J.P.1    Thompson, S.G.2
  • 19
    • 0030922816 scopus 로고    scopus 로고
    • Bias in meta-analysis detected by a simple, graphical test
    • M. Egger, G. Davey Smith, M. Schneider, and C. Minder Bias in meta-analysis detected by a simple, graphical test BMJ 315 1997 629 634
    • (1997) BMJ , vol.315 , pp. 629-634
    • Egger, M.1    Davey Smith, G.2    Schneider, M.3    Minder, C.4
  • 20
    • 0028659004 scopus 로고
    • Operating characteristics of a rank correlation test for publication bias
    • C.B. Begg, and M. Mazumdar Operating characteristics of a rank correlation test for publication bias Biometrics. 50 1994 1088 1101
    • (1994) Biometrics. , vol.50 , pp. 1088-1101
    • Begg, C.B.1    Mazumdar, M.2
  • 21
    • 0141540774 scopus 로고    scopus 로고
    • Mendelian randomisation: A new spin or real progress?
    • J. Little, and M.J. Khoury Mendelian randomisation: a new spin or real progress? Lancet. 362 2003 930 931
    • (2003) Lancet. , vol.362 , pp. 930-931
    • Little, J.1    Khoury, M.J.2
  • 22
    • 0037322022 scopus 로고    scopus 로고
    • 'Mendelian randomization': Can genetic epidemiology contribute to understanding environmental determinants of disease?
    • G. Davey Smith, and S. Ebrahim 'Mendelian randomization': can genetic epidemiology contribute to understanding environmental determinants of disease? Int J Epidemiol. 32 2003 1 22
    • (2003) Int J Epidemiol. , vol.32 , pp. 1-22
    • Davey Smith, G.1    Ebrahim, S.2
  • 23
    • 0035661847 scopus 로고    scopus 로고
    • The interleukin-6-174 G/C promoter polymorphism is associated with risk of coronary heart disease and systolic blood pressure in healthy men
    • S.E. Humphries, L.A. Luong, M.S. Ogg, E. Hawe, and G.J. Miller The interleukin-6-174 G/C promoter polymorphism is associated with risk of coronary heart disease and systolic blood pressure in healthy men Eur Heart J. 22 2001 2243 2252
    • (2001) Eur Heart J. , vol.22 , pp. 2243-2252
    • Humphries, S.E.1    Luong, L.A.2    Ogg, M.S.3    Hawe, E.4    Miller, G.J.5
  • 24
    • 0034945885 scopus 로고    scopus 로고
    • Interleukin-6 gene polymorphisms and susceptibility to myocardial infarction: The ECTIM study
    • J.-L. Georges, V. Loukaci, x000E, rie, O. Poirier, and A. Evans Interleukin-6 gene polymorphisms and susceptibility to myocardial infarction: the ECTIM study Journal of Molecular Medicine. 79 2001 300 305
    • (2001) Journal of Molecular Medicine. , vol.79 , pp. 300-305
    • Georges, J.-L.1    Loukaci, V.2    Rie, X.3    Poirier, O.4    Evans, A.5
  • 25
    • 0036123849 scopus 로고    scopus 로고
    • Interleukin-6-174G > C polymorphism and risk of coronary heart disease in West of Scotland Coronary Prevention Study (WOSCOPS)
    • F. Basso Interleukin-6-174G > C polymorphism and risk of coronary heart disease in West of Scotland Coronary Prevention Study (WOSCOPS) Arteriosclerosis, Thrombosis, and Vascular Biology 22 2002 599 604
    • (2002) Arteriosclerosis, Thrombosis, and Vascular Biology , vol.22 , pp. 599-604
    • Basso, F.1
  • 26
    • 0036373824 scopus 로고    scopus 로고
    • The interleukin-6 G(- 174)C promoter polymorphism in the LURIC cohort: No association with plasma interleukin-6, coronary artery disease, and myocardial infarction
    • M. Nauck, B. Winkelmann, M. Hoffmann, x000F, hm B, and H. Wieland The interleukin-6 G(- 174)C promoter polymorphism in the LURIC cohort: no association with plasma interleukin-6, coronary artery disease, and myocardial infarction Journal of Molecular Medicine. 80 2002 507 513
    • (2002) Journal of Molecular Medicine. , vol.80 , pp. 507-513
    • Nauck, M.1    Winkelmann, B.2    Hoffmann, M.3    Hm, B.4    Wieland, H.5
  • 27
    • 0344464788 scopus 로고    scopus 로고
    • Interleukin-6 serum levels and genotypes influence the risk for myocardial infarction
    • A. Bennet Interleukin-6 serum levels and genotypes influence the risk for myocardial infarction Atherosclerosis. 171 2003 359 367
    • (2003) Atherosclerosis. , vol.171 , pp. 359-367
    • Bennet, A.1
  • 28
    • 4644262151 scopus 로고    scopus 로고
    • No association of interleukin-6 gene polymorphism (?174 G/C) with myocardial infarction or traditional cardiovascular risk factors*1
    • W. Lieb No association of interleukin-6 gene polymorphism (?174 G/C) with myocardial infarction or traditional cardiovascular risk factors*1 International Journal of Cardiology. 97 2004 205 212
    • (2004) International Journal of Cardiology. , vol.97 , pp. 205-212
    • Lieb, W.1
  • 29
    • 4344617212 scopus 로고    scopus 로고
    • The concomitant presence of polymorphic alleles of interleukin-1β, interleukin-6 and apolipoprotein e is associated with an increased risk of myocardial infarction in elderly men
    • F. Licastro, M. Chiappelli, C.M. Caldarera, C. Tampieri, S. Nanni, and M. Gallina The concomitant presence of polymorphic alleles of interleukin-1β, interleukin-6 and apolipoprotein E is associated with an increased risk of myocardial infarction in elderly men Mechanisms of Ageing and Development. 125 2004 575 579
    • (2004) Mechanisms of Ageing and Development. , vol.125 , pp. 575-579
    • Licastro, F.1    Chiappelli, M.2    Caldarera, C.M.3    Tampieri, C.4    Nanni, S.5    Gallina, M.6
  • 30
    • 27944432628 scopus 로고    scopus 로고
    • Interaction between inflammation-related gene polymorphisms and cigarette smoking on the risk of myocardial infarction in the Physician's Health Study
    • S.A. Rosner, P.M. Ridker, R.Y.L. Zee, and N.R. Cook Interaction between inflammation-related gene polymorphisms and cigarette smoking on the risk of myocardial infarction in the Physician's Health Study Human Genetics. 118 2005 287 294
    • (2005) Human Genetics. , vol.118 , pp. 287-294
    • Rosner, S.A.1    Ridker, P.M.2    Zee, R.Y.L.3    Cook, N.R.4
  • 32
    • 33644820475 scopus 로고    scopus 로고
    • Interleukin 6-174 G/C promoter polymorphism and risk of coronary heart disease: Results from the Rotterdam study and a meta-analysis
    • M.P.S. Sie Interleukin 6-174 G/C promoter polymorphism and risk of coronary heart disease: results from the Rotterdam study and a meta-analysis Arteriosclerosis, Thrombosis, and Vascular Biology. 26 2006 212 217
    • (2006) Arteriosclerosis, Thrombosis, and Vascular Biology. , vol.26 , pp. 212-217
    • Sie, M.P.S.1
  • 33
    • 34547502657 scopus 로고    scopus 로고
    • No association of interleukin-6 gene polymorphism (- 174 G/C) with premature coronary artery disease in a Turkish cohort
    • C. Sekuri, F.S. Cam, A. Sagcan, E. Ercan, I. Tengiz, and E. Alioglu No association of interleukin-6 gene polymorphism (- 174 G/C) with premature coronary artery disease in a Turkish cohort Coron Artery Dis. 18 2007 333 337
    • (2007) Coron Artery Dis. , vol.18 , pp. 333-337
    • Sekuri, C.1    Cam, F.S.2    Sagcan, A.3    Ercan, E.4    Tengiz, I.5    Alioglu, E.6
  • 36
    • 79951830023 scopus 로고    scopus 로고
    • Genetic and environmental influences on the plasma interleukin-6 concentration in patients with a recent myocardial infarction: A case-control study
    • M. Bennermo, M. Nordin, P. Lundman, S. Boqvist, C. Held, and A. Samnegård Genetic and environmental influences on the plasma interleukin-6 concentration in patients with a recent myocardial infarction: a case-control study Journal of Interferon & Cytokine Research. 31 2011 259 264
    • (2011) Journal of Interferon & Cytokine Research. , vol.31 , pp. 259-264
    • Bennermo, M.1    Nordin, M.2    Lundman, P.3    Boqvist, S.4    Held, C.5    Samnegård, A.6
  • 37
    • 79952604371 scopus 로고    scopus 로고
    • Coronary heart disease and chronic periodontitis: Is polymorphism of interleukin-6 gene the common risk factor in a Chinese population?
    • W.H. Fan, D.L. Liu, L.M. Xiao, C.J. Xie, S.Y. Sun, and J.C. Zhang Coronary heart disease and chronic periodontitis: is polymorphism of interleukin-6 gene the common risk factor in a Chinese population? Oral Diseases. 17 2011 270 276
    • (2011) Oral Diseases. , vol.17 , pp. 270-276
    • Fan, W.H.1    Liu, D.L.2    Xiao, L.M.3    Xie, C.J.4    Sun, S.Y.5    Zhang, J.C.6
  • 38
    • 84862806726 scopus 로고    scopus 로고
    • Association between interleukin-6 promoter -174G/C polymorphism and coronary heart disease in Hubei Han population
    • J. Wang, J. Zeng, Z. Zhan, and W. Wang Association between interleukin-6 promoter -174G/C polymorphism and coronary heart disease in Hubei Han population Journal of Yunyang Medicial College. 24 2005 202 204
    • (2005) Journal of Yunyang Medicial College. , vol.24 , pp. 202-204
    • Wang, J.1    Zeng, J.2    Zhan, Z.3    Wang, W.4
  • 39
  • 40
    • 84859622637 scopus 로고    scopus 로고
    • Association of polymorphism in Interleukin-6 (IL-6) gene promoter region with morbidity of coronary heart disease
    • Y. Liu, J. Wang, L. Yu, H. Liu, F. Meng, and D. Liu Association of polymorphism in Interleukin-6 (IL-6) gene promoter region with morbidity of coronary heart disease Chinese Journal of Cardiovascular Review. 5 2007 264 266
    • (2007) Chinese Journal of Cardiovascular Review. , vol.5 , pp. 264-266
    • Liu, Y.1    Wang, J.2    Yu, L.3    Liu, H.4    Meng, F.5    Liu, D.6
  • 41
    • 50949084462 scopus 로고    scopus 로고
    • Mendelian randomisation and causal inference in observational epidemiology
    • N.A. Sheehan, V. Didelez, P.R. Burton, and M.D. Tobin Mendelian randomisation and causal inference in observational epidemiology PLoS Med. 5 2008 e177
    • (2008) PLoS Med. , vol.5 , pp. 177
    • Sheehan, N.A.1    Didelez, V.2    Burton, P.R.3    Tobin, M.D.4
  • 42
    • 51049105271 scopus 로고    scopus 로고
    • The role of tree nuts and peanuts in the prevention of coronary heart disease: Multiple potential mechanisms
    • P.M. Kris-Etherton, F.B. Hu, E. Ros, and J. Sabate The role of tree nuts and peanuts in the prevention of coronary heart disease: multiple potential mechanisms J Nutr. 138 2008 1746S 1751S
    • (2008) J Nutr. , vol.138
    • Kris-Etherton, P.M.1    Hu, F.B.2    Ros, E.3    Sabate, J.4
  • 43
    • 0032189103 scopus 로고    scopus 로고
    • The effect of novel polymorphisms in the interleukin-6 (IL-6) gene on IL-6 transcription and plasma IL-6 levels, and an association with systemic-onset juvenile chronic arthritis
    • D. Fishman, G. Faulds, R. Jeffery, V. Mohamed-Ali, J.S. Yudkin, and S. Humphries The effect of novel polymorphisms in the interleukin-6 (IL-6) gene on IL-6 transcription and plasma IL-6 levels, and an association with systemic-onset juvenile chronic arthritis J Clin Invest. 102 1998 1369 1376
    • (1998) J Clin Invest. , vol.102 , pp. 1369-1376
    • Fishman, D.1    Faulds, G.2    Jeffery, R.3    Mohamed-Ali, V.4    Yudkin, J.S.5    Humphries, S.6
  • 44
    • 0040780540 scopus 로고    scopus 로고
    • Cooperative influence of genetic polymorphisms on interleukin 6 transcriptional regulation
    • C.F. Terry, V. Loukaci, and F.R. Green Cooperative influence of genetic polymorphisms on interleukin 6 transcriptional regulation J Biol Chem. 275 2000 18138 18144
    • (2000) J Biol Chem. , vol.275 , pp. 18138-18144
    • Terry, C.F.1    Loukaci, V.2    Green, F.R.3
  • 45
    • 0036839228 scopus 로고    scopus 로고
    • Inflammation and immune responses in atherosclerosis
    • D.R. Greaves, and K.M. Channon Inflammation and immune responses in atherosclerosis Trends Immunol. 23 2002 535 541
    • (2002) Trends Immunol. , vol.23 , pp. 535-541
    • Greaves, D.R.1    Channon, K.M.2
  • 46
    • 0026702473 scopus 로고
    • Influence of collection and separation of blood samples on plasma IL-1, IL-6 and TNF-alpha concentrations
    • P. Riches, R. Gooding, B.C. Millar, and A.W. Rowbottom Influence of collection and separation of blood samples on plasma IL-1, IL-6 and TNF-alpha concentrations J Immunol Methods. 153 1992 125 131
    • (1992) J Immunol Methods. , vol.153 , pp. 125-131
    • Riches, P.1    Gooding, R.2    Millar, B.C.3    Rowbottom, A.W.4
  • 47
    • 77951702343 scopus 로고    scopus 로고
    • Genetic heterogeneity in human disease
    • J. McClellan, and M.C. King Genetic heterogeneity in human disease Cell. 141 2010 210 217
    • (2010) Cell. , vol.141 , pp. 210-217
    • McClellan, J.1    King, M.C.2
  • 48
    • 1942436221 scopus 로고    scopus 로고
    • Mendelian randomization: Prospects, potentials, and limitations
    • G.D. Smith, and S. Ebrahim Mendelian randomization: prospects, potentials, and limitations Int J Epidemiol. 33 2004 30 42
    • (2004) Int J Epidemiol. , vol.33 , pp. 30-42
    • Smith, G.D.1    Ebrahim, S.2
  • 50
    • 77957884628 scopus 로고    scopus 로고
    • Ethics in the authorship and publishing of scientific articles
    • L.G. Shewan, and A.J. Coats Ethics in the authorship and publishing of scientific articles Int J Cardiol. 144 2010 1 2
    • (2010) Int J Cardiol. , vol.144 , pp. 1-2
    • Shewan, L.G.1    Coats, A.J.2


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.