Genetic risk and gene-environment interaction in coronary artery spasm in Japanese men and women

European Heart Journal

Volumn 25, Issue 11, 2004, Pages 970-977

  Murase, Yosuke ^a,b   Yamada, Yoshiji ^c   Hirashiki, Akihiro ^a   Ichihara, Sahoko ^b,c   Kanda, Hirofumi ^a   Watarai, Masato ^d   Takatsu, Fumimaro ^d   Murohara, Toyoaki ^b   Yokota, Mitsuhiro ^b  

^a Okazaki City Hospital   (Japan)

^b NAGOYA UNIVERSITY GRADUATE SCHOOL OF MEDICINE   (Japan)

^c MIE UNIVERSITY   (Japan)

^d ANJO KOSEI HOSPITAL   (Japan)

Author keywords

Coronary artery spasm; Coronary risk factor; Genetics; Myocardial infarction; Polymorphism; Vasospastic angina

Indexed keywords

INTERLEUKIN 6; PRIMER DNA; REDUCED NICOTINAMIDE ADENINE DINUCLEOTIDE; REDUCED NICOTINAMIDE ADENINE DINUCLEOTIDE PHOSPHATE OXIDASE; STROMELYSIN;

ADULT; AGE DISTRIBUTION; ALLELE; ARTICLE; BODY MASS; CIGARETTE SMOKING; CONTROLLED STUDY; CORONARY ARTERY SPASM; DIABETES MELLITUS; DNA POLYMORPHISM; FEMALE; GENE EXPRESSION; GENE PROBE; GENETIC RISK; GENOTYPE ENVIRONMENT INTERACTION; HUMAN; HYPERCHOLESTEROLEMIA; HYPERTENSION; HYPERURICEMIA; LOGISTIC REGRESSION ANALYSIS; MAJOR CLINICAL STUDY; MALE; PRIORITY JOURNAL; RISK FACTOR; STATISTICAL SIGNIFICANCE;

CORONARY VASOSPASM; FEMALE; GENETIC PREDISPOSITION TO DISEASE; GENOTYPE; HUMANS; JAPAN; MALE; MIDDLE AGED; MULTIVARIATE ANALYSIS; POLYMORPHISM, GENETIC; REGRESSION ANALYSIS; RISK FACTORS;

EID: 3042795368     PISSN: 0195668X     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.ehj.2004.02.020     Document Type: Article

References (33)

1. Maseri A., L'Abbate A., Baroldi G., et al. Coronary vasospasm as a possible cause of myocardial infarction. A conclusion derived from the study of "preinfarction" angina. N. Engl. J. Med. 299:1978;1271-1277
2. Sugiishi M., Takatsu F. Cigarette smoking is a major risk factor for coronary spasm. Circulation. 87:1993;76-79
3. Pristipino C., Beltrame J.F., Finocchiaro M.L., et al. Major racial differences in coronary constrictor response between Japanese and Caucasians with recent myocardial infarction. Circulation. 101:2000;1102-1108
4. ′ -flanking region of the endothelial nitric oxide synthase gene is associated with coronary spasm Circulation. 99:1999;2864-2870
5. -786→C and missense Glu298Asp J. Invest. Med. 48:2000;367-374
6. Oike Y., Hata A., Ogata Y., et al. Angiotensin converting enzyme as a genetic risk factor for coronary artery spasm: implication in the pathogenesis of myocardial infarction. J. Clin. Invest. 96:1995;2975-2979
7. Amant C., Hamon M., Bauters C., et al. The angiotensin II type 1 receptor gene polymorphism is associated with coronary artery vasoconstriction. J. Am. Coll. Cardiol. 29:1997;486-490
8. Ito T., Yasue H., Yoshimura M., et al. Paraoxonase gene Gln192Arg (Q192R) polymorphism is associated with coronary artery spasm. Hum. Genet. 110:2002;89-94
9. Yamada Y., Izawa H., Ichihara S., et al. Prediction of the risk of myocardial infarction from polymorphisms in candidate genes. N. Engl. J. Med. 347:2002;1916-1923
10. Yasue H., Horio Y., Nakamura N., et al. Induction of coronary artery spasm by acetylcholine in patients with variant angina: possible role of the parasympathetic nervous system in the pathogenesis of coronary artery spasm. Circulation. 74:1986;955-963
11. Vanhoutte P.M., Shimokawa H. Endothelium-derived relaxing factor and coronary vasospasm. Circulation. 80:1989;1-9
12. Egashira K., Inou T., Yamada A., et al. Preserved endothelium-dependent vasodilation at the vasospastic site in patients with variant angina. J. Clin. Invest. 89:1992;1047-1052
13. Shimokawa H., Tomoike H., Nabeyama S., et al. Coronary artery spasm induced in atherosclerotic miniature swine. Science. 221:1983;560-562
14. Zeiher A.M., Schachinger V., Minners J. Long-term cigarette smoking impairs endothelium-dependent coronary arterial vasodilator function. Circulation. 92:1995;1094-1100
15. Kugiyama K., Yasue H., Ohgushi M., et al. Deficiency in nitric oxide bioactivity in epicardial coronary arteries of cigarette smokers. J. Am. Coll. Cardiol. 28:1996;1161-1167
16. Griendling K.K., Sorescu D., Ushio-Fukai M. NAD(P)H oxidase. Role in cardiovascular biology and disease. Circ. Res. 86:2000;494-501
17. phox in human coronary arteries. Circulation. 100:1999;1494-1498
18. Inoue N., Kawashima S., Kanazawa K., et al. Polymorphism of the NADH/NADPH oxidase p22 phox gene in patients with coronary artery disease. Circulation. 97:1998;135-137
19. Guzik T.J., West N.E.J., Black E., et al. Functional effect of the C242T polymorphism in the NAD(P)H oxidase p22phox gene on vascular superoxide production in atherosclerosis. Circulation. 102:2000;1744-1747
20. Woessner J.F. Jr. Matrix metalloproteinases and their inhibitors in connective tissue remodeling. FASEB J. 5:1991;2145-2154
21. Ye S., Watts G.F., Mandalia S., et al. Preliminary report: Genetic variation in the human stromelysin promoter is associated with progression of coronary atherosclerosis. Br. Heart J. 73:1995;209-215
22. Humphries S., Bauters C., Meirhaeghe A., et al. The 5A6A polymorphism in the promoter of the stromelysin-1 (MMP3) gene as a risk factor for restenosis. Eur. Heart J. 23:2002;721-725
23. Rauramaa R., Väisänen S.B., Luong L.-A., et al. Stromelysin-1 and interleukin-6 gene promoter polymorphisms are determinants of asymptomatic carotid artery atheroscleosis. Arterioscler. Thromb. Vasc. Biol. 20:2000;2657-2662
24. Rundek T., Elkind M.S., Pittman J., et al. Carotid intima-media thickness is associated with allelic variants of stromelysin-1, interleukin-6, and hepatic lipase genes: the Northern Manhattan Prospective Cohort Study. Stroke. 33:2002;1420-1423
25. Terashima M., Akita H., Kanazawa K., et al. Stromelysin promoter 5A/6A polymorphism is associated with acute myocardial infarction. Circulation. 99:1999;2717-2719
26. Heinrich P.C., Castell J.V., Andus T. Interleukin-6 and the acute phase response. Biochem J. 265:1990;621-636
27. Yudkin J.S., Stehouwer C.D., Emeis J.J., et al. C-reactive protein in healthy subjects: associations with obesity, insulin resistance, and endothelial dysfunction. A potential role for cytokines originating from adipose tissue? Arterioscler. Thromb. Vasc. Biol. 19:1999;972-978
28. Romano M., Sironi M., Toniatti C., et al. Role of IL-6 and its soluble receptor in induction of chemokines and leukocyte recruitment. Immunity. 6:1997;315-325
29. Dalmon J., Laurent M., Courtois G. The human β fibrinogen promoter contains a hepatocyte nuclear factor 1-dependent interleukin-6-responsive element. Mol. Cell. Biol. 13:1993;1183-1193
30. Biasucci L.M., Vitelli A., Liuzzo G., et al. Elevated levels of interleukin-6 in unstable angina. Circulation. 94:1996;874-877
31. Marenberg M.E., Risch N., Berkman L.F., et al. Genetic susceptibility to death from coronary heart disease in a study of twins. N. Engl. J. Med. 330:1994;1041-1046
32. Koh K.K. Effects of estrogen on the vascular wall: vasomotor function and inflammation. Cardiovasc. Res. 55:2002;714-726
33. Beltrame J.F., Sasayama S., Maseri A. Racial heterogeneity in coronary artery vasomotor reactivity: differences between Japanese and Caucasian patients. J. Am. Coll. Cardiol. 33:1999;1442-1452