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Volumn 41, Issue 3, 2013, Pages 665-682

Norcantharidin inhibits pre-replicative complexes assembly of HepG2 cells

Author keywords

Cell Cycle; DNA Replication; Norcantharidin; Pre replicative Complexes

Indexed keywords

CELL CYCLE PROTEIN 6; MINICHROMOSOME MAINTENANCE PROTEIN 2; MINICHROMOSOME MAINTENANCE PROTEIN 6; NORCANTHARIDIN;

EID: 84878414247     PISSN: 0192415X     EISSN: None     Source Type: Journal    
DOI: 10.1142/S0192415X13500468     Document Type: Article
Times cited : (13)

References (52)
  • 2
    • 0035997368 scopus 로고    scopus 로고
    • DNA replication in eukaryotic cells
    • DOI 10.1146/annurev.biochem.71.110601.135425
    • Bell, S.P. and A. Dutta. DNA replication in eukaryotic cells. Ann. Rev. Biochem. 71: 333-374, 2002. (Pubitemid 34800224)
    • (2002) Annual Review of Biochemistry , vol.71 , pp. 333-374
    • Bell, S.P.1    Dutta, A.2
  • 4
    • 40549130342 scopus 로고    scopus 로고
    • CDC6: From DNA replication to cell cycle checkpoints and oncogenesis
    • DOI 10.1093/carcin/bgm268
    • Borlado, L.R. and J. Mendez. CDC6: from DNA replication to cell cycle checkpoints and oncogenesis. Carcinogenesis 29: 237-243, 2008. (Pubitemid 351359661)
    • (2008) Carcinogenesis , vol.29 , Issue.2 , pp. 237-243
    • Borlado, L.R.1    Mendez, J.2
  • 5
    • 70349304953 scopus 로고    scopus 로고
    • Regulation of Cdc45 in the cell cycle and after DNA damage
    • Broderick, R. and H.P. Nasheuer. Regulation of Cdc45 in the cell cycle and after DNA damage. Biochem. Soc. Trans. 37: 926-930, 2009.
    • (2009) Biochem. Soc. Trans , vol.37 , pp. 926-930
    • Broderick, R.1    Nasheuer, H.P.2
  • 7
    • 0142184964 scopus 로고    scopus 로고
    • 2-terminal kinase signaling pathways in human hepatoma HepG2 cells
    • DOI 10.1038/sj.bjp.0705461
    • Chen, Y.N., C.C. Cheng, J.C. Chen, W. Tsauer and S.L. Hsu. Norcantharidin-induced apoptosis is via the extracellular signal-regulated kinase and c-Jun-NH2-terminal kinase signaling pathways in human hepatoma HepG2 cells. Br. J. Pharmacol. 140: 461-470, 2003. (Pubitemid 37330490)
    • (2003) British Journal of Pharmacology , vol.140 , Issue.3 , pp. 461-470
    • Chen, Y.-N.1    Cheng, C.-C.2    Chen, J.-C.3    Tsauer, W.4    Hsu, S.-L.5
  • 8
    • 36549025029 scopus 로고    scopus 로고
    • Norcantharidin induces anoikis through Jun-N-terminal kinase activation in CT26 colorectal cancer cells
    • Chen, Y.J., C.D. Kuo, Y.M. Tsai, C.C. Yu, G.S. Wang and H.F. Liao. Norcantharidin induces anoikis through Jun-N-terminal kinase activation in CT26 colorectal cancer cells. Anticancer Drug 19: 55-64, 2008.
    • (2008) Anticancer Drug , vol.19 , pp. 55-64
    • Chen, Y.J.1    Kuo, C.D.2    Tsai, Y.M.3    Yu, C.C.4    Wang, G.S.5    Liao, H.F.6
  • 9
    • 84857552738 scopus 로고    scopus 로고
    • Comparative analysis of pre-replication complex proteins in transformed and normal cells
    • Di Paola, D. and M. Zannis-Hadjopoulos. Comparative analysis of pre-replication complex proteins in transformed and normal cells. J. Cell. Biochem. 113: 1333-1347, 2012.
    • (2012) J. Cell. Biochem , vol.113 , pp. 1333-1347
    • Di Paola, D.1    Zannis-Hadjopoulos, M.2
  • 10
    • 0029807797 scopus 로고    scopus 로고
    • Once and only once upon a time: Specifying and regulating origins of DNA replication in eukaryotic cells
    • Diffley, J.F. Once and only once upon a time: specifying and regulating origins of DNA replication in eukaryotic cells. Genes Dev. 10: 2819-2830, 1996. (Pubitemid 26394243)
    • (1996) Genes and Development , vol.10 , Issue.22 , pp. 2819-2830
    • Diffley, J.F.X.1
  • 11
    • 23344451688 scopus 로고    scopus 로고
    • P53-dependent regulation of Cdc6 protein stability controls cellular proliferation
    • DOI 10.1128/MCB.25.16.6937-6947.2005
    • Duursma, A. and R. Agami. p53-Dependent regulation of Cdc6 protein stability controls cellular proliferation. Mol. Cell. Biol. 25: 6937-6947, 2005. (Pubitemid 41105894)
    • (2005) Molecular and Cellular Biology , vol.25 , Issue.16 , pp. 6937-6947
    • Duursma, A.1    Agami, R.2
  • 12
    • 33846967813 scopus 로고    scopus 로고
    • Inhibitory effect of norcantharidin on the growth of human gallbladder carcinoma GBC-SD cells in vitro
    • Fan, Y.Z., J.Y. Fu, Z.M. Zhao and C.Q. Chen. Inhibitory effect of norcantharidin on the growth of human gallbladder carcinoma GBC-SD cells in vitro. Hepatobiliary Pancreat. Dis. Int. 6: 72-80, 2007.
    • (2007) Hepatobiliary Pancreat. Dis. Int , vol.6 , pp. 72-80
    • Fan, Y.Z.1    Fu, J.Y.2    Zhao, Z.M.3    Chen, C.Q.4
  • 13
    • 58149143265 scopus 로고    scopus 로고
    • Expression of Mcm7 and Cdc6 in oral squamous cell carcinoma and precancerous lesions
    • Feng, C.J., H.J. Li, J.N. Li, Y.J. Lu and G.Q. Liao. Expression of Mcm7 and Cdc6 in oral squamous cell carcinoma and precancerous lesions. Anticancer Res. 28: 3763-3769, 2008.
    • (2008) Anticancer Res , vol.28 , pp. 3763-3769
    • Feng, C.J.1    Li, H.J.2    Li, J.N.3    Lu, Y.J.4    Liao, G.Q.5
  • 14
    • 0242610832 scopus 로고    scopus 로고
    • Inhibiting the expression of dna replication-initiation proteins induces apoptosis in human cancer cells
    • Feng, D., Z. Tu, W. Wu and C. Liang. Inhibiting the expression of DNA replication-initiation proteins induces apoptosis in human cancer cells. Cancer Res. 63: 7356-7364, 2003. (Pubitemid 37413477)
    • (2003) Cancer Research , vol.63 , Issue.21 , pp. 7356-7364
    • Feng, D.1    Tu, Z.2    Wu, W.3    Liang, C.4
  • 15
    • 1542405310 scopus 로고    scopus 로고
    • Eukaryotic MCM proteins: Beyond replication initiation
    • DOI 10.1128/MMBR.68.1.109-131.2004
    • Forsburg, S.L. Eukaryotic MCM proteins: beyond replication initiation. Microbiol. Mol. Biol. Rev. 68: 109-131, 2004. (Pubitemid 38339657)
    • (2004) Microbiology and Molecular Biology Reviews , vol.68 , Issue.1 , pp. 109-131
    • Forsburg, S.L.1
  • 16
    • 34447635904 scopus 로고    scopus 로고
    • Norcantharimides, synthesis and anticancer activity: Synthesis of new norcantharidin analogues and their anticancer evaluation
    • DOI 10.1016/j.bmc.2007.06.034, PII S0968089607005706
    • Hill, T.A., S.G. Stewart, S.P. Ackland, J. Gilbert, B. Sauer, J.A. Sakoff and A. McCluskey. Norcantharimides, synthesis and anticancer activity: Synthesis of new norcantharidin analogues and their anticancer evaluation. Bioorg. Med. Chem. 15: 6126-6134, 2007. (Pubitemid 47088962)
    • (2007) Bioorganic and Medicinal Chemistry , vol.15 , Issue.18 , pp. 6126-6134
    • Hill, T.A.1    Stewart, S.G.2    Ackland, S.P.3    Gilbert, J.4    Sauer, B.5    Sakoff, J.A.6    McCluskey, A.7
  • 17
    • 0035900689 scopus 로고    scopus 로고
    • Biochemical activities associated with mouse Mcm2 protein
    • Ishimi, Y., Y. Komamura-Kohno, K. Arai and H. Masai. Biochemical activities associated with mouse Mcm2 protein. J. Biol. Chem. 276: 42744-42752, 2001.
    • (2001) J. Biol. Chem , vol.276 , pp. 42744-42752
    • Ishimi, Y.1    Komamura-Kohno, Y.2    Arai, K.3    Masai, H.4
  • 20
    • 70249118531 scopus 로고    scopus 로고
    • The direct binding of Mrc1, a checkpoint mediator, to Mcm6, a replication helicase, is essential for the replication checkpoint against methyl methanesulfonate-induced stress
    • Komata, M., M. Bando, H. Araki and K. Shirahige. The direct binding of Mrc1, a checkpoint mediator, to Mcm6, a replication helicase, is essential for the replication checkpoint against methyl methanesulfonate-induced stress. Mol. Cell. Biol. 29: 5008-5019, 2009.
    • (2009) Mol. Cell. Biol , vol.29 , pp. 5008-5019
    • Komata, M.1    Bando, M.2    Araki, H.3    Shirahige, K.4
  • 21
    • 0035012849 scopus 로고    scopus 로고
    • Initiating DNA synthesis: From recruiting to activating the MCM complex
    • Lei, M. and B.K. Tye. Initiating DNA synthesis: from recruiting to activating the MCM complex. J. Cell. Sci. 114: 1447-1454, 2001. (Pubitemid 32427832)
    • (2001) Journal of Cell Science , vol.114 , Issue.8 , pp. 1447-1454
    • Lei, M.1    Tye, B.K.2
  • 22
    • 33646088119 scopus 로고    scopus 로고
    • Norcantharidin inhibits DNA replication and induces apoptosis with the cleavage of initiation protein Cdc6 in HL-60 cells
    • Li, J.L., Y.C. Cai, X.H. Liu and L.J. Xian. Norcantharidin inhibits DNA replication and induces apoptosis with the cleavage of initiation protein Cdc6 in HL-60 cells. Anticancer Drug. 17: 307-314, 2006.
    • (2006) Anticancer Drug , vol.17 , pp. 307-314
    • Li, J.L.1    Cai, Y.C.2    Liu, X.H.3    Xian, L.J.4
  • 23
    • 85027957316 scopus 로고    scopus 로고
    • Norcantharidin, a protective therapeutic agent in renal tubulointerstitial fibrosis
    • Li, Y., Y. Ge, F.Y. Liu, Y.M. Peng, L. Sun, J. Li, Q. Chen, Y. Sun and K. Ye. Norcantharidin, a protective therapeutic agent in renal tubulointerstitial fibrosis. Mol. Cell. Biochem. 361: 79-83, 2012.
    • (2012) Mol. Cell. Biochem , vol.361 , pp. 79-83
    • Li, Y.1    Ge, Y.2    Liu, F.Y.3    Peng, Y.M.4    Sun, L.5    Li, J.6    Chen, Q.7    Sun, Y.8    Ye, K.9
  • 24
    • 34547093861 scopus 로고    scopus 로고
    • Norcantharidin preferentially induces apoptosis in human leukemic Jurkat cells without affecting viability of normal blood mononuclear cells
    • Liao, H.F., S.L. Su, Y.J. Chen, C.H. Chou and C.D. Kuo. Norcantharidin preferentially induces apoptosis in human leukemic Jurkat cells without affecting viability of normal blood mononuclear cells. Food Chem. Toxicol. 45: 1678-1687, 2007.
    • (2007) Food Chem. Toxicol , vol.45 , pp. 1678-1687
    • Liao, H.F.1    Su, S.L.2    Chen, Y.J.3    Chou, C.H.4    Kuo, C.D.5
  • 25
    • 26244435980 scopus 로고    scopus 로고
    • CDK phosphorylation of a novel NLS-NES module distributed between two subunits of the Mcm2-7 complex prevents chromosomal rereplication
    • DOI 10.1091/mbc.E05-05-0412
    • Liku, M.E., V.Q. Nguyen, A.W. Rosales, K. Irie and J.J. Li. CDK phosphorylation of a novel NLSNES module distributed between two subunits of the Mcm2-7 complex prevents chromosomal rereplication. Mol. Biol. Cell 16: 5026-5039, 2005. (Pubitemid 41416479)
    • (2005) Molecular Biology of the Cell , vol.16 , Issue.10 , pp. 5026-5039
    • Liku, M.E.1    Nguyen, V.Q.2    Rosales, A.W.3    Irie, K.4    Li, J.J.5
  • 26
    • 0029850794 scopus 로고    scopus 로고
    • Efficacy of intra-arterial norcantharidin in suppressing tumour 14C-labelled glucose oxidative metabolism in rat Morris hepatoma
    • Mack, P.X., F. Ha and L.Y. Cheng. Efficacy of intra-arterial norcantharidin in suppressing tumour 14C-labelled glucose oxidative metabolism in rat Morris hepatoma. HPB Surg. 10: 65-72, 1996.
    • (1996) HPB Surg , vol.10 , pp. 65-72
    • MacK, P.X.1    Ha, F.2    Cheng, L.Y.3
  • 27
    • 0039600453 scopus 로고    scopus 로고
    • Stepwise regulated chromatin assembly of MCM2-7 proteins
    • DOI 10.1074/jbc.275.12.8426
    • Maiorano, D.J., M. Lemaitre and M. Mechali. Stepwise regulated chromatin assembly of MCM2-7 proteins. J. Biol. Chem. 275: 8426-8431, 2000. (Pubitemid 30180186)
    • (2000) Journal of Biological Chemistry , vol.275 , Issue.12 , pp. 8426-8431
    • Maiorano, D.1    Lemaitre, J.-M.2    Mechali, M.3
  • 29
    • 0344198460 scopus 로고    scopus 로고
    • Perpetuating the double helix: Molecular machines at eukaryotic DNA replication origins
    • DOI 10.1002/bies.10370
    • Mendez, J. and B. Stillman. Perpetuating the double helix: molecular machines at eukaryotic DNA replication origins. Bioessays 25: 1158-1167, 2003. (Pubitemid 37499316)
    • (2003) BioEssays , vol.25 , Issue.12 , pp. 1158-1167
    • Mendez, J.1    Stillman, B.2
  • 31
    • 0035963372 scopus 로고    scopus 로고
    • Cyclin-dependent kinases prevent DNA re-replication through multiple mechanisms
    • DOI 10.1038/35082600
    • Nguyen, V.Q., C. Co and J.J. Li. Cyclin-dependent kinases prevent DNA re-replication through multiple mechanisms. Nature 411: 1068-1073, 2001. (Pubitemid 32612333)
    • (2001) Nature , vol.411 , Issue.6841 , pp. 1068-1073
    • Nguyen, V.Q.1    Co, C.2    Li, J.J.3
  • 32
    • 0034708063 scopus 로고    scopus 로고
    • Clb/Cdc28 kinases promote nuclear export of the replication initiator proteins Mcm2-7
    • DOI 10.1016/S0960-9822(00)00337-7
    • Nguyen, V.Q., C. Co, K. Irie and J.J. Li. Clb/Cdc28 kinases promote nuclear export of the replication initiator proteins Mcm2-7. Curr. Biol. 10: 195-205, 2000. (Pubitemid 30146784)
    • (2000) Current Biology , vol.10 , Issue.4 , pp. 195-205
    • Nguyen, V.Q.1    Co, C.2    Irie, K.3    Li, J.J.4
  • 33
    • 2142808749 scopus 로고    scopus 로고
    • The role of Cdc6 in ensuring complete genome licensing and S phase checkpoint activation
    • DOI 10.1083/jcb.200311044
    • Oehlmann, M.A., J. Score and J.J. Blow. The role of Cdc6 in ensuring complete genome licensing and S phase checkpoint activation. J. Cell Biol. 165: 181-190, 2004. (Pubitemid 38544521)
    • (2004) Journal of Cell Biology , vol.165 , Issue.2 , pp. 181-190
    • Oehlmann, M.1    Score, A.J.2    Blow, J.J.3
  • 35
    • 0034723198 scopus 로고    scopus 로고
    • Sequential MCM/P1 subcomplex assembly is required to form a heterohexamer with replication licensing activity
    • DOI 10.1074/jbc.275.4.2491
    • Prokhorova, T.A. and J.J. Blow. Sequential MCM/P1 subcomplex assembly is required to form a heterohexamer with replication licensing activity. J. Biol. Chem. 275: 2491-2498, 2000. (Pubitemid 30082011)
    • (2000) Journal of Biological Chemistry , vol.275 , Issue.4 , pp. 2491-2498
    • Prokhorova, T.A.1    Blow, J.J.2
  • 38
    • 80052633822 scopus 로고    scopus 로고
    • Effects of Panax notoginseng saponins on proliferation and differentiation of rat hippocampal neural stem cells
    • Si, Y.C., J.P. Zhang, C.E. Xie, L.J. Zhang and X.N. Jiang. Effects of Panax notoginseng saponins on proliferation and differentiation of rat hippocampal neural stem cells. Am. J. Chin. Med. 39: 999-1013, 2011.
    • (2011) Am. J. Chin. Med , vol.39 , pp. 999-1013
    • Si, Y.C.1    Zhang, J.P.2    Xie, C.E.3    Zhang, L.J.4    Jiang, X.N.5
  • 39
    • 0029810269 scopus 로고    scopus 로고
    • Cell cycle control of DNA replication
    • DOI 10.1126/science.274.5293.1659
    • Stillman, B. Cell cycle control of DNA replication. Science 274: 1659-1664, 1996. (Pubitemid 26414888)
    • (1996) Science , vol.274 , Issue.5293 , pp. 1659-1664
    • Stillman, B.1
  • 40
    • 84864413863 scopus 로고    scopus 로고
    • Synthesis and anticancer activity of a series of norcantharidin analogues
    • Tarleton, M., J. Gilbert, J.A. Sakoff and A. McCluskey. Synthesis and anticancer activity of a series of norcantharidin analogues. Eur. J. Med. Chem. 54: 573-581, 2012.
    • (2012) Eur. J. Med. Chem , vol.54 , pp. 573-581
    • Tarleton, M.1    Gilbert, J.2    Sakoff, J.A.3    McCluskey, A.4
  • 41
    • 0033637837 scopus 로고    scopus 로고
    • Initiation of eukaryotic DNA replication: Origin unwinding and sequential chromatin association of Cdc45 RPA and DNA polymerase alpha
    • Walter, J. and J. Newport. Initiation of eukaryotic DNA replication: origin unwinding and sequential chromatin association of Cdc45, RPA, and DNA polymerase alpha. Mol. Cell 5: 617-627, 2000.
    • (2000) Mol. Cell , vol.5 , pp. 617-627
    • Walter, J.1    Newport, J.2
  • 47
    • 84867311835 scopus 로고    scopus 로고
    • Induction of apoptosis in human Hep3B hepatoma cells by norcantharidin through a p53 independent pathway via TRAIL/DR5 signal transduction
    • Yeh, C.H., Y.Y. Yang, Y.F. Huang, K.C. Chow and M.F. Chen. Induction of apoptosis in human Hep3B hepatoma cells by norcantharidin through a p53 independent pathway via TRAIL/DR5 signal transduction. Chin. J. Integr. Med. 18: 676-682, 2012.
    • (2012) Chin. J. Integr. Med , vol.18 , pp. 676-682
    • Yeh, C.H.1    Yang, Y.Y.2    Huang, Y.F.3    Chow, K.C.4    Chen, M.F.5
  • 49
    • 0141764727 scopus 로고    scopus 로고
    • Caspase-3-mediated cleavage of Cdc6 induces nuclear localization of p49-truncated Cdc6 and apoptosis
    • DOI 10.1091/mbc.E03-01-0029
    • Yim, H., Y.H. Jin, B.D. Park, H.J. Choi and S.K. Lee. Caspase-3-mediated cleavage of Cdc6 induces nuclear localization of p49-truncated Cdc6 and apoptosis. Mol. Biol. Cell 14: 4250-4259, 2003. (Pubitemid 37186325)
    • (2003) Molecular Biology of the Cell , vol.14 , Issue.10 , pp. 4250-4259
    • Yim, H.1    Jin, Y.H.2    Park, B.D.3    Choi, H.J.4    Lee, S.K.5
  • 50
    • 3242770626 scopus 로고    scopus 로고
    • Pairwise interactions of the six human MCM protein subunits
    • DOI 10.1016/j.jmb.2004.05.024, PII S0022283604005923
    • Yu, Z.D. Feng and C. Liang. Pairwise interactions of the six human MCM protein subunits. J. Mol. Biol. 340: 1197-1206, 2004. (Pubitemid 38968711)
    • (2004) Journal of Molecular Biology , vol.340 , Issue.5 , pp. 1197-1206
    • Yu, Z.1    Feng, D.2    Liang, C.3
  • 52
    • 84862638645 scopus 로고    scopus 로고
    • Norcantharidin enhances ABT-737-induced apoptosis in hepatocellular carcinoma cells by transcriptional repression of Mcl-1
    • Zhang, S., G. Li, X. Ma, Y. Wang, G. Liu, L. Feng, Y. Zhao, G. Zhang, Y. Wu and X. Ye. Norcantharidin enhances ABT-737-induced apoptosis in hepatocellular carcinoma cells by transcriptional repression of Mcl-1. Cell. Sign. 24: 1803-1809, 2012.
    • (2012) Cell. Sign , vol.24 , pp. 1803-1809
    • Zhang, S.1    Li, G.2    Ma, X.3    Wang, Y.4    Liu, G.5    Feng, L.6    Zhao, Y.7    Zhang, G.8    Wu, Y.9    Ye, X.10


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