Norcantharidin preferentially induces apoptosis in human leukemic Jurkat cells without affecting viability of normal blood mononuclear cells

Food and Chemical Toxicology

Volumn 45, Issue 9, 2007, Pages 1678-1687

  Liao, Hui Fen ^a,b   Su, Shu Li ^a   Chen, Yu Jen ^c   Chou, Chin Hung ^a   Kuo, Cheng Deng ^a,d  

^a TAIPEI VETERANS GENERAL HOSPITAL   (Taiwan)

^b NATIONAL CHIAYI UNIVERSITY   (Taiwan)

^c MACKAY MEMORIAL HOSPITAL   (Taiwan)

^d NATIONAL YANG MING UNIVERSITY   (Taiwan)

Author keywords

Apoptosis; Caspase; Cytokine; Jurkat cell; Norcantharidin

Indexed keywords

APOPTOSIS INDUCING FACTOR; ATM PROTEIN; CASPASE 3; CASPASE 9; CASPASE INHIBITOR; CYTOCHROME C; FAS ANTIBODY; FAS LIGAND; GRANULOCYTE MACROPHAGE COLONY STIMULATING FACTOR; INTERLEUKIN 10; MELANOMA GROWTH STIMULATORY ACTIVITY FACTOR; MONOCYTE CHEMOTACTIC PROTEIN 1; NICOTINAMIDE ADENINE DINUCLEOTIDE ADENOSINE DIPHOSPHATE RIBOSYLTRANSFERASE; NORCANTHARIDIN; PROTEIN BAX; PROTEIN BCL 2; PROTEIN P63; RANTES; STAT1 PROTEIN; TUMOR NECROSIS FACTOR ALPHA; UNCLASSIFIED DRUG; VAD FMK;

APOPTOSIS; ARTICLE; CELL VIABILITY; CONTROLLED STUDY; DOSE RESPONSE; DRUG MECHANISM; HUMAN; HUMAN CELL; LEUKEMIA CELL LINE; MONONUCLEAR CELL; PROTEIN EXPRESSION;

ANTINEOPLASTIC AGENTS; APOPTOSIS; BICYCLO COMPOUNDS, HETEROCYCLIC; BLOTTING, WESTERN; CASPASES; CELL PROLIFERATION; CELL SURVIVAL; CYTOKINES; DNA; DOSE-RESPONSE RELATIONSHIP, DRUG; FLOW CYTOMETRY; HUMANS; JURKAT CELLS; LEUKOCYTES, MONONUCLEAR; MAP KINASE SIGNALING SYSTEM; S PHASE; TIME FACTORS;

ATAXIA TELANGIECTASIA;

EID: 34547093861     PISSN: 02786915     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.fct.2007.03.003     Document Type: Article

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