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Volumn 40, Issue 3, 2013, Pages 2097-2105

Disruption of the transcription factor RBP-J results in osteopenia attributable to attenuated osteoclast differentiation

Author keywords

Notch signaling; Osteoclasts; Osteopenia; RBP J

Indexed keywords

ACID PHOSPHATASE TARTRATE RESISTANT ISOENZYME; NOTCH RECEPTOR; TRANSCRIPTION FACTOR; TRANSCRIPTION FACTOR RBP J; UNCLASSIFIED DRUG;

EID: 84878398150     PISSN: 03014851     EISSN: 15734978     Source Type: Journal    
DOI: 10.1007/s11033-012-2268-6     Document Type: Article
Times cited : (15)

References (46)
  • 1
    • 0344826782 scopus 로고    scopus 로고
    • Bone's mechanostat: A 2003 update
    • 14613308 10.1002/ar.a.10119
    • Frost HM (2003) Bone's mechanostat: a 2003 update. Anat Rec A Discov Mol Cell Evol Biol 275(2):1081-1101
    • (2003) Anat Rec A Discov Mol Cell Evol Biol , vol.275 , Issue.2 , pp. 1081-1101
    • Frost, H.M.1
  • 2
    • 34447132814 scopus 로고    scopus 로고
    • Skeletal remodeling in health and disease
    • 17618270 10.1038/nm1593 1:CAS:528:DC%2BD2sXnsFWmtro%3D
    • Zaidi M (2007) Skeletal remodeling in health and disease. Nat Med 13(7):791-801
    • (2007) Nat Med , vol.13 , Issue.7 , pp. 791-801
    • Zaidi, M.1
  • 3
    • 84856783815 scopus 로고    scopus 로고
    • Update on bone anabolics in osteoporosis treatment: Rationale, current status, and perspectives
    • 22238383 10.1210/jc.2011-2332 1:CAS:528:DC%2BC38XisFOgt70%3D
    • Baron R, Hesse E (2012) Update on bone anabolics in osteoporosis treatment: rationale, current status, and perspectives. J Clin Endocrinol Metab 97(2):311-325
    • (2012) J Clin Endocrinol Metab , vol.97 , Issue.2 , pp. 311-325
    • Baron, R.1    Hesse, E.2
  • 4
    • 0037673945 scopus 로고    scopus 로고
    • Osteoclast differentiation and activation
    • 12748652 10.1038/nature01658 1:CAS:528:DC%2BD3sXjs1ynu7g%3D
    • Boyle WJ, Simonet WS, Lacey DL (2003) Osteoclast differentiation and activation. Nature 423(6937):337-342
    • (2003) Nature , vol.423 , Issue.6937 , pp. 337-342
    • Boyle, W.J.1    Simonet, W.S.2    Lacey, D.L.3
  • 5
    • 56749102181 scopus 로고    scopus 로고
    • Osteoclastogenesis-current knowledge and future perspectives
    • 18799853 1:CAS:528:DC%2BD1cXhsFSns77E
    • Yavropoulou MP, Yovos JG (2008) Osteoclastogenesis-current knowledge and future perspectives. J Musculoskelet Neuronal Interact 8(3):204-216
    • (2008) J Musculoskelet Neuronal Interact , vol.8 , Issue.3 , pp. 204-216
    • Yavropoulou, M.P.1    Yovos, J.G.2
  • 7
    • 0025332897 scopus 로고
    • The murine mutation osteopetrosis is in the coding region of the macrophage colony stimulating factor gene
    • 2188141 10.1038/345442a0 1:CAS:528:DyaK3cXktlGktrs%3D
    • Yoshida H, Hayashi S, Kunisada T, Ogawa M, Nishikawa S, Okamura H, Sudo T, Shultz LD, Nishikawa S (1990) The murine mutation osteopetrosis is in the coding region of the macrophage colony stimulating factor gene. Nature 345(6274):442-444
    • (1990) Nature , vol.345 , Issue.6274 , pp. 442-444
    • Yoshida, H.1    Hayashi, S.2    Kunisada, T.3    Ogawa, M.4    Nishikawa, S.5    Okamura, H.6    Sudo, T.7    Shultz, L.D.8    Nishikawa, S.9
  • 8
    • 0036218666 scopus 로고    scopus 로고
    • RANK-L and RANK: T cells, bone loss, and mammalian evolution
    • 11861618 10.1146/annurev.immunol.20.100301.064753 1:CAS:528: DC%2BD38XjtlWgtbo%3D
    • Theill LE, Boyle WJ, Penninger JM (2002) RANK-L and RANK: T cells, bone loss, and mammalian evolution. Annu Rev Immunol 20:795-823
    • (2002) Annu Rev Immunol , vol.20 , pp. 795-823
    • Theill, L.E.1    Boyle, W.J.2    Penninger, J.M.3
  • 10
    • 0032493737 scopus 로고    scopus 로고
    • Characterization of the intracellular domain of receptor activator of NF-KB (RANK). Interaction with tumor necrosis factor receptor-associated factors and activation of NF-KB and c-Jun N-terminal kinase
    • 9685412 10.1074/jbc.273.32.20551 1:CAS:528:DyaK1cXlsVWgu7w%3D
    • Darnay BG, Haridas V, Ni J, Moore PA, Aggarwal BB (1998) Characterization of the intracellular domain of receptor activator of NF-KB (RANK). Interaction with tumor necrosis factor receptor-associated factors and activation of NF-KB and c-Jun N-terminal kinase. J Biol Chem 273(32):20551-20555
    • (1998) J Biol Chem , vol.273 , Issue.32 , pp. 20551-20555
    • Darnay, B.G.1    Haridas, V.2    Ni, J.3    Moore, P.A.4    Aggarwal, B.B.5
  • 12
    • 0032561198 scopus 로고    scopus 로고
    • The TRAF family of signal transducers mediates NF-kB activation by the TRANCE receptor
    • 9774460 10.1074/jbc.273.43.28355 1:CAS:528:DyaK1cXntVClsL4%3D
    • Wong BR, Josien R, Lee SY, Vologodskaia M, Steinman R, Choi M (1998) The TRAF family of signal transducers mediates NF-kB activation by the TRANCE receptor. J Biol Chem 273(43):28355-28359
    • (1998) J Biol Chem , vol.273 , Issue.43 , pp. 28355-28359
    • Wong, B.R.1    Josien, R.2    Lee, S.Y.3    Vologodskaia, M.4    Steinman, R.5    Choi, M.6
  • 15
    • 28544434439 scopus 로고    scopus 로고
    • Fos/AP-1 proteins in bone and the immune system
    • 16313345 10.1111/j.0105-2896.2005.00332.x 1:CAS:528: DC%2BD28Xks1eitw%3D%3D
    • Wagner EF, Efer R (2005) Fos/AP-1 proteins in bone and the immune system. Immunol Rev 208:126-140
    • (2005) Immunol Rev , vol.208 , pp. 126-140
    • Wagner, E.F.1    Efer, R.2
  • 16
    • 0037468892 scopus 로고    scopus 로고
    • Multiple tissue-specific promoters control expression of the murine tartrate-resistant acid phosphatase gene
    • 12706893 10.1016/S0378-1119(03)00449-9 1:CAS:528:DC%2BD3sXjtFajsb8%3D
    • Walsh NC, Cahill M, Carninci P, Kawai J, Okazaki Y, Hayashizaki Y, Hume DA, Cassady AI (2003) Multiple tissue-specific promoters control expression of the murine tartrate-resistant acid phosphatase gene. Gene 307:111-123
    • (2003) Gene , vol.307 , pp. 111-123
    • Walsh, N.C.1    Cahill, M.2    Carninci, P.3    Kawai, J.4    Okazaki, Y.5    Hayashizaki, Y.6    Hume, D.A.7    Cassady, A.I.8
  • 17
    • 0035826866 scopus 로고    scopus 로고
    • Linking osteopetrosis and pycnodysostosis: Regulation of cathepsin K expression by the microphthalmia transcription factor family
    • 11331755 10.1073/pnas.091479298 1:CAS:528:DC%2BD3MXjs1Wntr0%3D
    • Motyckova G, Weilbaecher KN, Horstmann M, Rieman DJ, Fisher DZ, Fisher DE (2001) Linking osteopetrosis and pycnodysostosis: regulation of cathepsin K expression by the microphthalmia transcription factor family. Proc Natl Acad Sci USA 98(10):5798-5803
    • (2001) Proc Natl Acad Sci USA , vol.98 , Issue.10 , pp. 5798-5803
    • Motyckova, G.1    Weilbaecher, K.N.2    Horstmann, M.3    Rieman, D.J.4    Fisher, D.Z.5    Fisher, D.E.6
  • 18
    • 33747623018 scopus 로고    scopus 로고
    • Notch signaling: A simple pathway becomes complex
    • 16921404 10.1038/nrm2009 1:CAS:528:DC%2BD28Xot12isr4%3D
    • Bray SJ (2006) Notch signaling: a simple pathway becomes complex. Nat Rev Mol Cell Biol 7(9):678-689
    • (2006) Nat Rev Mol Cell Biol , vol.7 , Issue.9 , pp. 678-689
    • Bray, S.J.1
  • 19
    • 0035988246 scopus 로고    scopus 로고
    • Inducible gene knockout of transcription factor recombination signal binding protein-J reveals its essential role in T versus B lineage decision
    • 12039915 10.1093/intimm/dxf030 1:CAS:528:DC%2BD38Xkslyqsrc%3D
    • Han H, Tanigaki K, Yamamoto N, Kuroda K, Yoshimoto M, Nakahata T, Ikuta K, Honjo T (2002) Inducible gene knockout of transcription factor recombination signal binding protein-J reveals its essential role in T versus B lineage decision. Int Immunol 14(6):637-645
    • (2002) Int Immunol , vol.14 , Issue.6 , pp. 637-645
    • Han, H.1    Tanigaki, K.2    Yamamoto, N.3    Kuroda, K.4    Yoshimoto, M.5    Nakahata, T.6    Ikuta, K.7    Honjo, T.8
  • 20
    • 48149109123 scopus 로고    scopus 로고
    • Notch signaling in osteoblasts
    • 18445833 10.1126/stke.117pe17
    • Canalis E (2008) Notch signaling in osteoblasts. Sci Signal 1(17):pe17
    • (2008) Sci Signal , vol.1 , Issue.17 , pp. 17
    • Canalis, E.1
  • 21
    • 47949130093 scopus 로고    scopus 로고
    • Notch inhibits osteoblast differentiation and causes osteopenia
    • 18420737 10.1210/en.2008-0140 1:CAS:528:DC%2BD1cXptlamsbg%3D
    • Zanotti S, Smerdel-Ramoya A, Stadmeyer L, Durant D, Radtke F, Canalis E (2008) Notch inhibits osteoblast differentiation and causes osteopenia. Endocrinology 149(8):3890-3899
    • (2008) Endocrinology , vol.149 , Issue.8 , pp. 3890-3899
    • Zanotti, S.1    Smerdel-Ramoya, A.2    Stadmeyer, L.3    Durant, D.4    Radtke, F.5    Canalis, E.6
  • 23
    • 33646550902 scopus 로고    scopus 로고
    • Notch 1 overexpression inhibits osteoblastogenesis by suppressing Wnt/beta-catenin but not bone morphogenetic protein signaling
    • 16407293 10.1074/jbc.M508370200 1:CAS:528:DC%2BD28XhvFOhtbk%3D
    • Deregowski V, Gazzerro E, Priest L, Rydziel S, Canalis E (2006) Notch 1 overexpression inhibits osteoblastogenesis by suppressing Wnt/beta-catenin but not bone morphogenetic protein signaling. J Biol Chem 281(10):6203-6210
    • (2006) J Biol Chem , vol.281 , Issue.10 , pp. 6203-6210
    • Deregowski, V.1    Gazzerro, E.2    Priest, L.3    Rydziel, S.4    Canalis, E.5
  • 24
    • 74249112642 scopus 로고    scopus 로고
    • NOTCHing the bone: Insight into multi-functionality
    • 19520195 10.1016/j.bone.2009.05.027 1:CAS:528:DC%2BC3cXpslartw%3D%3D
    • Engin F, Lee B (2010) NOTCHing the bone: Insight into multi-functionality. Bone 46(2):274-280
    • (2010) Bone , vol.46 , Issue.2 , pp. 274-280
    • Engin, F.1    Lee, B.2
  • 25
    • 84867923420 scopus 로고    scopus 로고
    • Role of notch signaling in osteoimmunology - From the standpoint of osteoclast differentiation
    • Duan L, Ren Y (2012) Role of notch signaling in osteoimmunology - from the standpoint of osteoclast differentiation. Eur J Orthod
    • (2012) Eur J Orthod
    • Duan, L.1    Ren, Y.2
  • 26
    • 52049110474 scopus 로고    scopus 로고
    • Notch is activated in RANKL-induced osteoclast differentiation and resorption
    • 18508716 10.2741/3210 1:CAS:528:DC%2BD1cXnsVOiu7g%3D
    • Duan L, de Vos P, Fan M, Ren Y (2008) Notch is activated in RANKL-induced osteoclast differentiation and resorption. Front Biosci 13:7064-7071
    • (2008) Front Biosci , vol.13 , pp. 7064-7071
    • Duan, L.1    De Vos, P.2    Fan, M.3    Ren, Y.4
  • 27
    • 0037443389 scopus 로고    scopus 로고
    • Regulation of osteoclast development by Notch signaling directed to osteoclast precursors and through stromal cells
    • 10.1182/blood-2002-06-1740
    • Yamada T, Yamazaki H, Yamane T, Yoshino M, Okuyama H, Tsuneto M, Kurino T, Hayashi S, Sakano S (2003) Regulation of osteoclast development by Notch signaling directed to osteoclast precursors and through stromal cells. Blood 15(6):2227-2234
    • (2003) Blood , vol.15 , Issue.6 , pp. 2227-2234
    • Yamada, T.1    Yamazaki, H.2    Yamane, T.3    Yoshino, M.4    Okuyama, H.5    Tsuneto, M.6    Kurino, T.7    Hayashi, S.8    Sakano, S.9
  • 28
    • 42749095897 scopus 로고    scopus 로고
    • Notch1 regulates osteoclastogenesis directly in osteoclast precursors and indirectly via c-fos osteoblast lineage cells
    • 18156632 10.1074/jbc.M707000200 1:CAS:528:DC%2BD1cXisFOkt74%3D
    • Bai S, Kopan R, Zou W, Hilton MJ, Ong CT, Long F, Ross FP, Teitelbaum SL (2008) Notch1 regulates osteoclastogenesis directly in osteoclast precursors and indirectly via c-fos osteoblast lineage cells. J Biol Chem 283(10):6509-6518
    • (2008) J Biol Chem , vol.283 , Issue.10 , pp. 6509-6518
    • Bai, S.1    Kopan, R.2    Zou, W.3    Hilton, M.J.4    Ong, C.T.5    Long, F.6    Ross, F.P.7    Teitelbaum, S.L.8
  • 29
    • 53549111642 scopus 로고    scopus 로고
    • The association of Notch2 and NF-kappaB accelerates RANKL-induced osteoclastogenesis
    • 18710934 10.1128/MCB.00299-08 1:CAS:528:DC%2BD1cXht1CitL7M
    • Fukushima H, Nakao A, Okamoto F, Shin M, Kajiya H, Sakano S, Bigas A, Jimi E, Okabe K (2008) The association of Notch2 and NF-kappaB accelerates RANKL-induced osteoclastogenesis. Mol Cell Biol 28(20):6402-6412
    • (2008) Mol Cell Biol , vol.28 , Issue.20 , pp. 6402-6412
    • Fukushima, H.1    Nakao, A.2    Okamoto, F.3    Shin, M.4    Kajiya, H.5    Sakano, S.6    Bigas, A.7    Jimi, E.8    Okabe, K.9
  • 30
    • 84857672132 scopus 로고    scopus 로고
    • Differential regulation of osteoclastogenesis by Notch2/Delta-like 1 and Notch1/Jagged1 axes
    • 22390640 10.1186/ar3758 1:CAS:528:DC%2BC38Xlsl2lsbs%3D
    • Sekine C, Koyanagi A, Koyama N, Hozumi K, Chiba S, Yagita H (2012) Differential regulation of osteoclastogenesis by Notch2/Delta-like 1 and Notch1/Jagged1 axes. Arthritis Res Ther 14(2):R45
    • (2012) Arthritis Res Ther , vol.14 , Issue.2 , pp. 45
    • Sekine, C.1    Koyanagi, A.2    Koyama, N.3    Hozumi, K.4    Chiba, S.5    Yagita, H.6
  • 31
    • 84863116031 scopus 로고    scopus 로고
    • TNF-induced osteoclastogenesis and inflammatory bone resorption are inhibited by transcription factor RBP-J
    • 22249448 10.1084/jem.20111566 1:CAS:528:DC%2BC38Xis1Krs7o%3D
    • Zhao B, Grimes SN, Li S, Hu X, Ivashkiv LB (2012) TNF-induced osteoclastogenesis and inflammatory bone resorption are inhibited by transcription factor RBP-J. J Exp Med 209(2):319-334
    • (2012) J Exp Med , vol.209 , Issue.2 , pp. 319-334
    • Zhao, B.1    Grimes, S.N.2    Li, S.3    Hu, X.4    Ivashkiv, L.B.5
  • 32
    • 0029155706 scopus 로고
    • Inducible gene targeting in mice
    • 7660125 10.1126/science.7660125 1:STN:280:DyaK2MzovFWlug%3D%3D
    • Kuhn R, Schwent F, Aguet M, Rajewsky K (1995) Inducible gene targeting in mice. Science 269(5229):1427-1429
    • (1995) Science , vol.269 , Issue.5229 , pp. 1427-1429
    • Kuhn, R.1    Schwent, F.2    Aguet, M.3    Rajewsky, K.4
  • 33
    • 0033177995 scopus 로고    scopus 로고
    • Conditional gene targeting in macrophages and granulocytes using LysMcre mice
    • 10621974 10.1023/A:1008942828960 1:CAS:528:DyaK1MXnsFSjtbw%3D
    • Clausen BE, Burkhardt C, Reith W, Renkawitz R, Forster I (1999) Conditional gene targeting in macrophages and granulocytes using LysMcre mice. Transgenic Res 8(4):265-277
    • (1999) Transgenic Res , vol.8 , Issue.4 , pp. 265-277
    • Clausen, B.E.1    Burkhardt, C.2    Reith, W.3    Renkawitz, R.4    Forster, I.5
  • 34
    • 67650173025 scopus 로고    scopus 로고
    • Lipopolysaccharide-induced maturation of bone marrow-derived DCs is regulated by Notch signaling through the up-regulation of CXCR4
    • 19357083 10.1074/jbc.M901144200 1:CAS:528:DC%2BD1MXmsF2jsr8%3D
    • Wang YC, Hu XB, He F, Feng F, Wang L, Li W, Zhang P, Li D, Jia ZS, Liang YM, Han H (2009) Lipopolysaccharide-induced maturation of bone marrow-derived DCs is regulated by Notch signaling through the up-regulation of CXCR4. J Biol Chem 284(23):15993-16003
    • (2009) J Biol Chem , vol.284 , Issue.23 , pp. 15993-16003
    • Wang, Y.C.1    Hu, X.B.2    He, F.3    Feng, F.4    Wang, L.5    Li, W.6    Zhang, P.7    Li, D.8    Jia, Z.S.9    Liang, Y.M.10    Han, H.11
  • 35
    • 0036092801 scopus 로고    scopus 로고
    • Targeted disruption of the mouse colony-stimulating factor 1 receptor gene results in osteopetrosis, mononuclear phagocyte deficiency, increased primitive progenitor cell frequencies, and reproductive defects
    • 11756160 10.1182/blood.V99.1.111 1:CAS:528:DC%2BD38XivF2isA%3D%3D
    • Dai XM, Ryan GR, Hapel AJ, Dominguez MG, Russell RG, Kapp S, Sylvestre V, Stanley ER (2002) Targeted disruption of the mouse colony-stimulating factor 1 receptor gene results in osteopetrosis, mononuclear phagocyte deficiency, increased primitive progenitor cell frequencies, and reproductive defects. Blood 99(1):111-120
    • (2002) Blood , vol.99 , Issue.1 , pp. 111-120
    • Dai, X.M.1    Ryan, G.R.2    Hapel, A.J.3    Dominguez, M.G.4    Russell, R.G.5    Kapp, S.6    Sylvestre, V.7    Stanley, E.R.8
  • 36
    • 77953752609 scopus 로고    scopus 로고
    • Notch signaling determines the M1 versus M2 polarization of macrophages in antitumor immune responses
    • 20501839 10.1158/0008-5472.CAN-10-0269 1:CAS:528:DC%2BC3cXntlKltrY%3D
    • Wang YC, He F, Feng F, Liu XW, Dong GY, Qin HY, Hu XB, Zheng MH, Liang L, Feng L, Liang YM, Han H (2010) Notch signaling determines the M1 versus M2 polarization of macrophages in antitumor immune responses. Cancer Res 70(12):4840-4849
    • (2010) Cancer Res , vol.70 , Issue.12 , pp. 4840-4849
    • Wang, Y.C.1    He, F.2    Feng, F.3    Liu, X.W.4    Dong, G.Y.5    Qin, H.Y.6    Hu, X.B.7    Zheng, M.H.8    Liang, L.9    Feng, L.10    Liang, Y.M.11    Han, H.12
  • 39
    • 77951229591 scopus 로고    scopus 로고
    • RBPJkappa-dependent Notch signaling regulates mesenchymal progenitor cell proliferation and differentiation during skeletal development
    • 20335360 10.1242/dev.042911 1:CAS:528:DC%2BC3cXnt1Gmu7o%3D
    • Dong Y, Jesse AM, Kohn A, Gunnell LM, Honjo T, Zuscik MJ, O'Keefe RJ, Hilton MJ (2010) RBPJkappa-dependent Notch signaling regulates mesenchymal progenitor cell proliferation and differentiation during skeletal development. Development 137(9):1461-1471
    • (2010) Development , vol.137 , Issue.9 , pp. 1461-1471
    • Dong, Y.1    Jesse, A.M.2    Kohn, A.3    Gunnell, L.M.4    Honjo, T.5    Zuscik, M.J.6    O'Keefe, R.J.7    Hilton, M.J.8
  • 41
    • 33846031926 scopus 로고    scopus 로고
    • The molecular understanding of osteoclast differentiation
    • 17098490 10.1016/j.bone.2006.09.023 1:CAS:528:DC%2BD2sXmtVCrtA%3D%3D
    • Asagiri M, Takayanagi H (2007) The molecular understanding of osteoclast differentiation. Bone 40(2):251-264
    • (2007) Bone , vol.40 , Issue.2 , pp. 251-264
    • Asagiri, M.1    Takayanagi, H.2
  • 42
    • 0039778099 scopus 로고    scopus 로고
    • Intracellular fragmentation of bone resorption products by reactive oxygen species generated by osteoclastic tartrate-resistant acid phosphatase
    • 10438453 10.1074/jbc.274.33.22907 1:CAS:528:DyaK1MXltlKnsL8%3D
    • Halleen JM, Räisänen S, Salo JJ, Reddy SV, Roodman GD, Hentunen TA, Lehenkari PP, Kaija H, Vihko P, Väänänen HK (1999) Intracellular fragmentation of bone resorption products by reactive oxygen species generated by osteoclastic tartrate-resistant acid phosphatase. J Biol Chem 274(33):22907-22910
    • (1999) J Biol Chem , vol.274 , Issue.33 , pp. 22907-22910
    • Halleen, J.M.1    Räisänen, S.2    Salo, J.J.3    Reddy, S.V.4    Roodman, G.D.5    Hentunen, T.A.6    Lehenkari, P.P.7    Kaija, H.8    Vihko, P.9    Väänänen, H.K.10
  • 43
    • 0033962845 scopus 로고    scopus 로고
    • Transgenic mice overexpressing tartrate-resistant acid phosphatase exhibit an increased rate of bone turnover
    • 10646119 10.1359/jbmr.2000.15.1.103 1:CAS:528:DC%2BD3cXmsVyguw%3D%3D
    • Angel NZ, Walsh N, Forwood MR, Ostrowski MC, Cassady AI, Hume DA (2000) Transgenic mice overexpressing tartrate-resistant acid phosphatase exhibit an increased rate of bone turnover. J Bone Miner Res 15(1):103-110
    • (2000) J Bone Miner Res , vol.15 , Issue.1 , pp. 103-110
    • Angel, N.Z.1    Walsh, N.2    Forwood, M.R.3    Ostrowski, M.C.4    Cassady, A.I.5    Hume, D.A.6
  • 44
    • 65549086411 scopus 로고    scopus 로고
    • Defective co-activator recruitment in osteoclasts from microphthalmia-oak ridge mutant mice
    • 19288495 10.1002/jcp.21755 1:CAS:528:DC%2BD1MXmvVGitbk%3D
    • Sharma SM, Sif S, Ostrowski MC, Sankar U (2009) Defective co-activator recruitment in osteoclasts from microphthalmia-oak ridge mutant mice. J Cell Physiol 220(1):230-237
    • (2009) J Cell Physiol , vol.220 , Issue.1 , pp. 230-237
    • Sharma, S.M.1    Sif, S.2    Ostrowski, M.C.3    Sankar, U.4


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