메뉴 건너뛰기




Volumn 209, Issue 2, 2012, Pages 319-334

TNF-induced osteoclastogenesis and inflammatory bone resorption are inhibited by transcription factor RBP-J

Author keywords

[No Author keywords available]

Indexed keywords

ACID PHOSPHATASE TARTRATE RESISTANT ISOENZYME; B LYMPHOCYTE INDUCED MATURATION PROTEIN 1; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; IMMUNOGLOBULIN J RECOMBINATION SIGNAL SEQUENCE BINDING PROTEIN; INTERFERON CONSENSUS SEQUENCE BINDING PROTEIN; JAGGED1; MESSENGER RNA; OSTEOCLAST DIFFERENTIATION FACTOR; PROTEIN C FOS; TRANSCRIPTION FACTOR; TRANSCRIPTION FACTOR AP 1; TRANSCRIPTION FACTOR NFATC1; TUMOR NECROSIS FACTOR; UNCLASSIFIED DRUG;

EID: 84863116031     PISSN: 00221007     EISSN: 15409538     Source Type: Journal    
DOI: 10.1084/jem.20111566     Document Type: Article
Times cited : (159)

References (58)
  • 2
    • 0034681337 scopus 로고    scopus 로고
    • Tumor necrosis factor-alpha induces differentiation of and bone resorption by osteoclasts
    • Azuma, Y., K. Kaji, R. Katogi, S. Takeshita, and A. Kudo. 2000. Tumor necrosis factor-alpha induces differentiation of and bone resorption by osteoclasts. J. Biol. Chem. 275:4858-4864. http://dx.doi.org/10.1074/jbc.275.7.4858
    • (2000) J. Biol. Chem. , vol.275 , pp. 4858-4864
    • Azuma, Y.1    Kaji, K.2    Katogi, R.3    Takeshita, S.4    Kudo, A.5
  • 3
    • 42749095897 scopus 로고    scopus 로고
    • NOTCH1 regulates osteoclastogenesis directly in osteoclast precursors and indirectly via osteoblast lineage cells
    • Bai, S., R. Kopan, W. Zou, M.J. Hilton, C.T. Ong, F. Long, F.P. Ross, and S.L. Teitelbaum. 2008. NOTCH1 regulates osteoclastogenesis directly in osteoclast precursors and indirectly via osteoblast lineage cells. J. Biol. Chem. 283:6509-6518. http://dx.doi.org/10.1074/jbc.M707000200
    • (2008) J. Biol. Chem. , vol.283 , pp. 6509-6518
    • Bai, S.1    Kopan, R.2    Zou, W.3    Hilton, M.J.4    Ong, C.T.5    Long, F.6    Ross, F.P.7    Teitelbaum, S.L.8
  • 4
    • 33645236232 scopus 로고    scopus 로고
    • PTF1 is an organ-specific and Notch-independent basic helix-loop-helix complex containing the mammalian Suppressor of Hairless (RBP-J) or its paralogue
    • Beres, T.M., T. Masui, G.H. Swift, L. Shi, R.M. Henke, and R.J. MacDonald. 2006. PTF1 is an organ-specific and Notch-independent basic helix-loop-helix complex containing the mammalian Suppressor of Hairless (RBP-J) or its paralogue, RBP-L. Mol. Cell. Biol. 26:117- 130. http://dx.doi.org/10.1128/MCB.26.1.117-130.2006
    • (2006) RBP-L. Mol. Cell. Biol. , vol.26 , pp. 117-130
    • Beres, T.M.1    Masui, T.2    Swift, G.H.3    Shi, L.4    Henke, R.M.5    MacDonald, R.J.6
  • 5
    • 33748091692 scopus 로고    scopus 로고
    • Osteoclast precursors: cytokinestimulated immunomodulators of inflammatory bone disease
    • Boyce, B.F., E.M. Schwarz, and L. Xing. 2006. Osteoclast precursors: cytokinestimulated immunomodulators of inflammatory bone disease. Curr. Opin. Rheumatol. 18:427-432. http://dx.doi.org/10.1097/01.bor.0000231913.32364.32
    • (2006) Curr. Opin. Rheumatol. , vol.18 , pp. 427-432
    • Boyce, B.F.1    Schwarz, E.M.2    Xing, L.3
  • 6
    • 34447275920 scopus 로고    scopus 로고
    • Notch-RBP-J signaling controls the homeostasis of CD8- dendritic cells in the spleen
    • Caton, M.L., M.R. Smith-Raska, and B. Reizis. 2007. Notch-RBP-J signaling controls the homeostasis of CD8- dendritic cells in the spleen. J. Exp. Med. 204:1653-1664.
    • (2007) J. Exp. Med. , vol.204 , pp. 1653-1664
    • Caton, M.L.1    Smith-Raska, M.R.2    Reizis, B.3
  • 7
    • 74249112642 scopus 로고    scopus 로고
    • NOTCHing the bone: insights into multifunctionality
    • Engin, F., and B. Lee. 2010. NOTCHing the bone: insights into multifunctionality. Bone. 46:274-280. http://dx.doi.org/10.1016/j.bone.2009.05.027
    • (2010) Bone , vol.46 , pp. 274-280
    • Engin, F.1    Lee, B.2
  • 9
    • 78149475633 scopus 로고    scopus 로고
    • Autoamplification of Notch signaling in macrophages by TLR-induced and RBP-J-dependent induction of Jagged1
    • Foldi, J., A.Y. Chung, H. Xu, J. Zhu, H.H. Outtz, J. Kitajewski, Y. Li, X. Hu, and L.B. Ivashkiv. 2010. Autoamplification of Notch signaling in macrophages by TLR-induced and RBP-J-dependent induction of Jagged1. J. Immunol. 185:5023-5031. http://dx.doi.org/10.4049/jimmunol.1001544
    • (2010) J. Immunol. , vol.185 , pp. 5023-5031
    • Foldi, J.1    Chung, A.Y.2    Xu, H.3    Zhu, J.4    Outtz, H.H.5    Kitajewski, J.6    Li, Y.7    Hu, X.8    Ivashkiv, L.B.9
  • 11
    • 3342964330 scopus 로고    scopus 로고
    • Viral interactions with the Notch pathway
    • Hayward, S.D. 2004. Viral interactions with the Notch pathway. Semin. Cancer Biol. 14:387-396. http://dx.doi.org/10.1016/j.semcancer.2004.04.018
    • (2004) Semin. Cancer Biol. , vol.14 , pp. 387-396
    • Hayward, S.D.1
  • 14
    • 34347356549 scopus 로고    scopus 로고
    • Eos, MITF, and PU 1 recruit corepressors to osteoclast-specific genes in committed myeloid progenitors
    • Hu, R., S.M. Sharma, A. Bronisz, R. Srinivasan, U. Sankar, and M.C. Ostrowski. 2007. Eos, MITF, and PU.1 recruit corepressors to osteoclast-specific genes in committed myeloid progenitors. Mol. Cell. Biol. 27:4018-4027. http://dx.doi.org/10.1128/MCB.01839-06
    • (2007) Mol. Cell. Biol. , vol.27 , pp. 4018-4027
    • Hu, R.1    Sharma, S.M.2    Bronisz, A.3    Srinivasan, R.4    Sankar, U.5    Ostrowski, M.C.6
  • 15
    • 55349128861 scopus 로고    scopus 로고
    • Integrated regulation of Toll-like receptor responses by Notch and interferon-gamma pathways
    • Hu, X., A.Y. Chung, I. Wu, J. Foldi, J. Chen, J.D. Ji, T. Tateya, Y.J. Kang, J. Han, M. Gessler, et al. 2008. Integrated regulation of Toll-like receptor responses by Notch and interferon-gamma pathways. Immunity. 29:691-703. http://dx.doi.org/10.1016/j.immuni.2008.08.016
    • (2008) Immunity , vol.29 , pp. 691-703
    • Hu, X.1    Chung, A.Y.2    Wu, I.3    Foldi, J.4    Chen, J.5    Ji, J.D.6    Tateya, T.7    Kang, Y.J.8    Han, J.9    Gessler, M.10
  • 17
    • 0043074740 scopus 로고    scopus 로고
    • The JAK/STAT pathway in rheumatoid arthritis: pathogenic or protective?
    • Ivashkiv, L.B., and X. Hu. 2003. The JAK/STAT pathway in rheumatoid arthritis: pathogenic or protective? Arthritis Rheum. 48:2092-2096. http://dx.doi.org/10.1002/art.11095
    • (2003) Arthritis Rheum , vol.48 , pp. 2092-2096
    • Ivashkiv, L.B.1    Hu, X.2
  • 18
    • 66149112412 scopus 로고    scopus 로고
    • NF-kappaB serves as a cellular sensor of Kaposi's sarcomaassociated herpesvirus latency and negatively regulates K-Rta by antagonizing the RBP-Jkappa coactivator
    • Izumiya, Y., C. Izumiya, D. Hsia, T.J. Ellison, P.A. Luciw, and H.J. Kung. 2009. NF-kappaB serves as a cellular sensor of Kaposi's sarcomaassociated herpesvirus latency and negatively regulates K-Rta by antagonizing the RBP-Jkappa coactivator. J. Virol. 83:4435-4446. http://dx.doi.org/10.1128/JVI.01999-08
    • (2009) J. Virol. , vol.83 , pp. 4435-4446
    • Izumiya, Y.1    Izumiya, C.2    Hsia, D.3    Ellison, T.J.4    Luciw, P.A.5    Kung, H.J.6
  • 20
    • 34147132897 scopus 로고    scopus 로고
    • MafB negatively regulates RANKL-mediated osteoclast differentiation
    • Kim, K., J.H. Kim, J. Lee, H.M. Jin, H. Kook, K.K. Kim, S.Y. Lee, and N. Kim. 2007. MafB negatively regulates RANKL-mediated osteoclast differentiation. Blood. 109:3253-3259. http://dx.doi.org/10.1182/blood-2006-09-048249
    • (2007) Blood , vol.109 , pp. 3253-3259
    • Kim, K.1    Kim, J.H.2    Lee, J.3    Jin, H.M.4    Kook, H.5    Kim, K.K.6    Lee, S.Y.7    Kim, N.8
  • 22
    • 0034677177 scopus 로고    scopus 로고
    • Tumor necrosis factor alpha stimulates osteoclast differentiation by a mechanism independent of the ODF/RANKLRANK interaction
    • Kobayashi, K., N. Takahashi, E. Jimi, N. Udagawa, M. Takami, S. Kotake, N. Nakagawa, M. Kinosaki, K. Yamaguchi, N. Shima, et al. 2000. Tumor necrosis factor alpha stimulates osteoclast differentiation by a mechanism independent of the ODF/RANKLRANK interaction. J. Exp. Med. 191:275-286. http://dx.doi.org/10.1084/jem.191.2.275
    • (2000) J. Exp. Med. , vol.191 , pp. 275-286
    • Kobayashi, K.1    Takahashi, N.2    Jimi, E.3    Udagawa, N.4    Takami, M.5    Kotake, S.6    Nakagawa, N.7    Kinosaki, M.8    Yamaguchi, K.9    Shima, N.10
  • 23
    • 64249172203 scopus 로고    scopus 로고
    • The canonical Notch signaling pathway: unfolding the activation mechanism
    • Kopan, R., and M.X. Ilagan. 2009. The canonical Notch signaling pathway: unfolding the activation mechanism. Cell. 137:216-233. http://dx.doi.org/10.1016/j.cell.2009.03.045
    • (2009) Cell , vol.137 , pp. 216-233
    • Kopan, R.1    Ilagan, M.X.2
  • 24
    • 0034523328 scopus 로고    scopus 로고
    • TNF- alpha induces osteoclastogenesis by direct stimulation of macrophages exposed to permissive levels of RANK ligand
    • Lam, J., S. Takeshita, J.E. Barker, O. Kanagawa, F.P. Ross, and S.L. Teitelbaum. 2000. TNF-alpha induces osteoclastogenesis by direct stimulation of macrophages exposed to permissive levels of RANK ligand. J. Clin. Invest. 106:1481-1488. http://dx.doi.org/10.1172/JCI11176
    • (2000) J. Clin. Invest. , vol.106 , pp. 1481-1488
    • Lam, J.1    Takeshita, S.2    Barker, J.E.3    Kanagawa, O.4    Ross, F.P.5    Teitelbaum, S.L.6
  • 25
    • 33645519588 scopus 로고    scopus 로고
    • Id helix-loop-helix proteins negatively regulate TRANCE-mediated osteoclast differentiation
    • Lee, J., K. Kim, J.H. Kim, H.M. Jin, H.K. Choi, S.H. Lee, H. Kook, K.K. Kim, Y. Yokota, S.Y. Lee, et al. 2006. Id helix-loop-helix proteins negatively regulate TRANCE-mediated osteoclast differentiation. Blood. 107:2686-2693. http://dx.doi.org/10.1182/blood-2005-07-2798
    • (2006) Blood , vol.107 , pp. 2686-2693
    • Lee, J.1    Kim, K.2    Kim, J.H.3    Jin, H.M.4    Choi, H.K.5    Lee, S.H.6    Kook, H.7    Kim, K.K.8    Yokota, Y.9    Lee, S.Y.10
  • 26
    • 12944262423 scopus 로고    scopus 로고
    • RANK is the intrinsic hematopoietic cell surface receptor that controls osteoclastogenesis and regulation of bone mass and calcium metabolism
    • Li, J., I. Sarosi, X.Q. Yan, S. Morony, C. Capparelli, H.L. Tan, S. McCabe, R. Elliott, S. Scully, G. Van, et al. 2000. RANK is the intrinsic hematopoietic cell surface receptor that controls osteoclastogenesis and regulation of bone mass and calcium metabolism. Proc. Natl. Acad. Sci. USA. 97:1566-1571. http://dx.doi.org/10.1073/pnas.97.4.1566
    • (2000) Proc. Natl. Acad. Sci. USA. , vol.97 , pp. 1566-1571
    • Li, J.1    Sarosi, I.2    Yan, X.Q.3    Morony, S.4    Capparelli, C.5    Tan, H.L.6    McCabe, S.7    Elliott, R.8    Scully, S.9    Van, G.10
  • 27
    • 1642526641 scopus 로고    scopus 로고
    • RANK signaling is not required for TNFalpha-mediated increase in CD11(hi) osteoclast precursors but is essential for mature osteoclast formation in TNFalpha-mediated inflammatory arthritis
    • Li, P., E.M. Schwarz, R.J. O'Keefe, L. Ma, B.F. Boyce, and L. Xing. 2004. RANK signaling is not required for TNFalpha-mediated increase in CD11(hi) osteoclast precursors but is essential for mature osteoclast formation in TNFalpha-mediated inflammatory arthritis. J. Bone Miner. Res. 19:207-213. http://dx.doi.org/10.1359/JBMR.0301233
    • (2004) J. Bone Miner. Res. , vol.19 , pp. 207-213
    • Li, P.1    Schwarz, E.M.2    O'Keefe, R.J.3    Ma, L.4    Boyce, B.F.5    Xing, L.6
  • 28
    • 0035936797 scopus 로고    scopus 로고
    • The TNF and TNF receptor superfamilies: integrating mammalian biology
    • Locksley, R.M., N. Killeen, and M.J. Lenardo. 2001. The TNF and TNF receptor superfamilies: integrating mammalian biology. Cell. 104:487- 501. http://dx.doi.org/10.1016/S0092-8674(01)00237-9
    • (2001) Cell , vol.104 , pp. 487-501
    • Locksley, R.M.1    Killeen, N.2    Lenardo, M.J.3
  • 29
    • 17644382970 scopus 로고    scopus 로고
    • Regulation of lymphoid development, differentiation, and function by the Notch pathway
    • Maillard, I., T. Fang, and W.S. Pear. 2005. Regulation of lymphoid development, differentiation, and function by the Notch pathway. Annu. Rev. Immunol. 23:945-974. http://dx.doi.org/10.1146/annurev.immunol.23.021704.115747
    • (2005) Annu. Rev. Immunol. , vol.23 , pp. 945-974
    • Maillard, I.1    Fang, T.2    Pear, W.S.3
  • 31
    • 0344736673 scopus 로고    scopus 로고
    • Notch signaling controls multiple steps of pancreatic differentiation
    • Murtaugh, L.C., B.Z. Stanger, K.M. Kwan, and D.A. Melton. 2003. Notch signaling controls multiple steps of pancreatic differentiation. Proc. Natl. Acad. Sci. USA. 100:14920-14925. http://dx.doi.org/10.1073/pnas.2436557100
    • (2003) Proc. Natl. Acad. Sci. USA. , vol.100 , pp. 14920-14925
    • Murtaugh, L.C.1    Stanger, B.Z.2    Kwan, K.M.3    Melton, D.A.4
  • 33
    • 39649091772 scopus 로고    scopus 로고
    • The osteoclast: friend or foe?
    • Novack, D.V., and S.L. Teitelbaum. 2008. The osteoclast: friend or foe? Annu. Rev. Pathol. 3:457-484. http://dx.doi.org/10.1146/annurev.pathmechdis.3.121806.151431
    • (2008) Annu. Rev. Pathol. , vol.3 , pp. 457-484
    • Novack, D.V.1    Teitelbaum, S.L.2
  • 35
    • 0030990093 scopus 로고    scopus 로고
    • Recombination signal sequence binding protein Jkappa is constitutively bound to the NF-kappaB site of the interleukin-6 promoter and acts as a negative regulatory factor
    • Plaisance, S., W. Vanden Berghe, E. Boone, W. Fiers, and G. Haegeman. 1997. Recombination signal sequence binding protein Jkappa is constitutively bound to the NF-kappaB site of the interleukin-6 promoter and acts as a negative regulatory factor. Mol. Cell. Biol. 17:3733-3743.
    • (1997) Mol. Cell. Biol. , vol.17 , pp. 3733-3743
    • Plaisance, S.1    Vanden Berghe, W.2    Boone, E.3    Fiers, W.4    Haegeman, G.5
  • 36
    • 70649086092 scopus 로고    scopus 로고
    • BIRAC Consortium; YEAR Consortium. Genetic variants at CD28 PRDM1 and CD2/CD58 are associated with rheumatoid arthritis risk
    • Raychaudhuri, S., B.P. Thomson, E.F. Remmers, S. Eyre, A. Hinks, C. Guiducci, J.J. Catanese, G. Xie, E.A. Stahl, R. Chen, et al; BIRAC Consortium; YEAR Consortium. 2009. Genetic variants at CD28, PRDM1 and CD2/CD58 are associated with rheumatoid arthritis risk. Nat. Genet. 41:1313-1318. http://dx.doi.org/10.1038/ng.479
    • (2009) Nat. Genet. , vol.41 , pp. 1313-1318
    • Raychaudhuri, S.1    Thomson, B.P.2    Remmers, E.F.3    Eyre, S.4    Hinks, A.5    Guiducci, C.6    Catanese, J.J.7    Xie, G.8    Stahl, E.A.9    Chen, R.10
  • 37
    • 0035502975 scopus 로고    scopus 로고
    • Factor recruitment and TIF2/GRIP1 corepressor activity at a collagenase-3 response element that mediates regulation by phorbol esters and hormones
    • Rogatsky, I., K.A. Zarember, and K.R. Yamamoto. 2001. Factor recruitment and TIF2/GRIP1 corepressor activity at a collagenase-3 response element that mediates regulation by phorbol esters and hormones. EMBO J. 20:6071-6083. http://dx.doi.org/10.1093/emboj/20.21.6071
    • (2001) EMBO J , vol.20 , pp. 6071-6083
    • Rogatsky, I.1    Zarember, K.A.2    Yamamoto, K.R.3
  • 38
    • 70349232591 scopus 로고    scopus 로고
    • Osteoclasts and arthritis
    • Schett, G., and S.L. Teitelbaum. 2009. Osteoclasts and arthritis. J. Bone Miner. Res. 24:1142-1146. http://dx.doi.org/10.1359/jbmr.090533
    • (2009) J. Bone Miner. Res. , vol.24 , pp. 1142-1146
    • Schett, G.1    Teitelbaum, S.L.2
  • 39
    • 77953692968 scopus 로고    scopus 로고
    • Targeting TNF for Treatment of Cancer and Autoimmunity
    • Sethi, G., B. Sung, A.B. Kunnumakkara, and B.B. Aggarwal. 2009. Targeting TNF for Treatment of Cancer and Autoimmunity. Adv. Exp. Med. Biol. 647:37-51. http://dx.doi.org/10.1007/978-0-387-89520-8_3
    • (2009) Adv. Exp. Med. Biol. , vol.647 , pp. 37-51
    • Sethi, G.1    Sung, B.2    Kunnumakkara, A.B.3    Aggarwal, B.B.4
  • 40
    • 79751472667 scopus 로고    scopus 로고
    • Tumor-derived JAGGED1 promotes osteolytic bone metastasis of breast cancer by engaging notch signaling in bone cells
    • Sethi, N., X. Dai, C.G. Winter, and Y. Kang. 2011. Tumor-derived JAGGED1 promotes osteolytic bone metastasis of breast cancer by engaging notch signaling in bone cells. Cancer Cell. 19:192-205. http://dx.doi.org/10.1016/j.ccr.2010.12.022
    • (2011) Cancer Cell , vol.19 , pp. 192-205
    • Sethi, N.1    Dai, X.2    Winter, C.G.3    Kang, Y.4
  • 41
    • 57349182470 scopus 로고    scopus 로고
    • Stabilized beta-catenin functions through TCF/LEF proteins and the Notch/RBP-Jkappa complex to promote proliferation and suppress differentiation of neural precursor cells
    • Shimizu, T., T. Kagawa, T. Inoue, A. Nonaka, S. Takada, H. Aburatani, and T. Taga. 2008. Stabilized beta-catenin functions through TCF/LEF proteins and the Notch/RBP-Jkappa complex to promote proliferation and suppress differentiation of neural precursor cells. Mol. Cell. Biol. 28:7427-7441. http://dx.doi.org/10.1128/MCB.01962-07
    • (2008) Mol. Cell. Biol. , vol.28 , pp. 7427-7441
    • Shimizu, T.1    Kagawa, T.2    Inoue, T.3    Nonaka, A.4    Takada, S.5    Aburatani, H.6    Taga, T.7
  • 43
    • 77952888454 scopus 로고    scopus 로고
    • BIRAC Consortium; YEAR Consortium. Genome-wide association study meta-analysis identifies seven new rheumatoid arthritis risk loci
    • Stahl, E.A., S. Raychaudhuri, E.F. Remmers, G. Xie, S. Eyre, B.P. Thomson, Y. Li, F.A. Kurreeman, A. Zhernakova, A. Hinks, et al; BIRAC Consortium; YEAR Consortium. 2010. Genome-wide association study meta-analysis identifies seven new rheumatoid arthritis risk loci. Nat. Genet. 42:508-514. http://dx.doi.org/10.1038/ng.582
    • (2010) Nat. Genet. , vol.42 , pp. 508-514
    • Stahl, E.A.1    Raychaudhuri, S.2    Remmers, E.F.3    Xie, G.4    Eyre, S.5    Thomson, B.P.6    Li, Y.7    Kurreeman, F.A.8    Zhernakova, A.9    Hinks, A.10
  • 44
    • 33947583822 scopus 로고    scopus 로고
    • Osteoimmunology: shared mechanisms and crosstalk between the immune and bone systems
    • Takayanagi, H. 2007. Osteoimmunology: shared mechanisms and crosstalk between the immune and bone systems. Nat. Rev. Immunol. 7:292-304. http://dx.doi.org/10.1038/nri2062
    • (2007) Nat. Rev. Immunol. , vol.7 , pp. 292-304
    • Takayanagi, H.1
  • 46
    • 0031983193 scopus 로고    scopus 로고
    • LIM protein KyoT2 negatively regulates transcription by association with the RBP-J DNA-binding protein
    • Taniguchi, Y., T. Furukawa, T. Tun, H. Han, and T. Honjo. 1998. LIM protein KyoT2 negatively regulates transcription by association with the RBP-J DNA-binding protein. Mol. Cell. Biol. 18:644-654.
    • (1998) Mol. Cell. Biol. , vol.18 , pp. 644-654
    • Taniguchi, Y.1    Furukawa, T.2    Tun, T.3    Han, H.4    Honjo, T.5
  • 47
    • 77957671886 scopus 로고    scopus 로고
    • Osteosclerosis owing to Notch gain of function is solely Rbpj-dependent
    • Tao, J., S. Chen, T. Yang, B. Dawson, E. Munivez, T. Bertin, and B. Lee. 2010. Osteosclerosis owing to Notch gain of function is solely Rbpj-dependent. J. Bone Miner. Res. 25:2175-2183. http://dx.doi.org/10.1002/jbmr.115
    • (2010) J. Bone Miner. Res. , vol.25 , pp. 2175-2183
    • Tao, J.1    Chen, S.2    Yang, T.3    Dawson, B.4    Munivez, E.5    Bertin, T.6    Lee, B.7
  • 48
    • 70349967965 scopus 로고    scopus 로고
    • Anti-TNF biologic agents: still the therapy of choice for rheumatoid arthritis
    • Taylor, P.C., and M. Feldmann. 2009. Anti-TNF biologic agents: still the therapy of choice for rheumatoid arthritis. Nat Rev Rheumatol. 5:578- 582. http://dx.doi.org/10.1038/nrrheum.2009.181
    • (2009) Nat Rev Rheumatol , vol.5 , pp. 578-582
    • Taylor, P.C.1    Feldmann, M.2
  • 49
    • 33144481680 scopus 로고    scopus 로고
    • Osteoclasts; culprits in inflammatory osteolysis
    • Teitelbaum, S.L. 2006. Osteoclasts; culprits in inflammatory osteolysis. Arthritis Res. Ther. 8:201. http://dx.doi.org/10.1186/ar1857
    • (2006) Arthritis Res. Ther. , vol.8 , pp. 201
    • Teitelbaum, S.L.1
  • 52
    • 0037443389 scopus 로고    scopus 로고
    • Regulation of osteoclast development by Notch signaling directed to osteoclast precursors and through stromal cells
    • Yamada, T., H. Yamazaki, T. Yamane, M. Yoshino, H. Okuyama, M. Tsuneto, T. Kurino, S. Hayashi, and S. Sakano. 2003. Regulation of osteoclast development by Notch signaling directed to osteoclast precursors and through stromal cells. Blood. 101:2227-2234. http://dx.doi.org/10.1182/blood-2002-06-1740
    • (2003) Blood , vol.101 , pp. 2227-2234
    • Yamada, T.1    Yamazaki, H.2    Yamane, T.3    Yoshino, M.4    Okuyama, H.5    Tsuneto, M.6    Kurino, T.7    Hayashi, S.8    Sakano, S.9
  • 53
    • 33744955055 scopus 로고    scopus 로고
    • Tumor necrosis factor-alpha increases circulating osteoclast precursor numbers by promoting their proliferation and differentiation in the bone marrow through up-regulation of c-Fms expression
    • Yao, Z., P. Li, Q. Zhang, E.M. Schwarz, P. Keng, A. Arbini, B.F. Boyce, and L. Xing. 2006. Tumor necrosis factor-alpha increases circulating osteoclast precursor numbers by promoting their proliferation and differentiation in the bone marrow through up-regulation of c-Fms expression. J. Biol. Chem. 281:11846-11855. http://dx.doi.org/10.1074/jbc.M512624200
    • (2006) J. Biol. Chem. , vol.281 , pp. 11846-11855
    • Yao, Z.1    Li, P.2    Zhang, Q.3    Schwarz, E.M.4    Keng, P.5    Arbini, A.6    Boyce, B.F.7    Xing, L.8
  • 54
    • 70349705616 scopus 로고    scopus 로고
    • NF- kappaB p100 limits TNFinduced bone resorption in mice by a TRAF3-dependent mechanism
    • Yao, Z., L. Xing, and B.F. Boyce. 2009. NF-kappaB p100 limits TNFinduced bone resorption in mice by a TRAF3-dependent mechanism. J. Clin. Invest. 119:3024-3034. http://dx.doi.org/10.1172/JCI38716
    • (2009) J. Clin. Invest. , vol.119 , pp. 3024-3034
    • Yao, Z.1    Xing, L.2    Boyce, B.F.3
  • 55
    • 33846922783 scopus 로고    scopus 로고
    • Suppression of the effector phase of inflammatory arthritis by double-stranded RNA is mediated by type I IFNs
    • Yarilina, A., E. DiCarlo, and L.B. Ivashkiv. 2007. Suppression of the effector phase of inflammatory arthritis by double-stranded RNA is mediated by type I IFNs. J. Immunol. 178:2204-2211.
    • (2007) J. Immunol. , vol.178 , pp. 2204-2211
    • Yarilina, A.1    DiCarlo, E.2    Ivashkiv, L.B.3
  • 57
    • 81255213678 scopus 로고    scopus 로고
    • Negative regulation of osteoclastogenesis and bone resorption by cytokines and transcriptional repressors
    • Zhao, B., and L.B. Ivashkiv. 2011. Negative regulation of osteoclastogenesis and bone resorption by cytokines and transcriptional repressors. Arthritis Res. Ther. 13:234-243. http://dx.doi.org/10.1186/ar3379
    • (2011) Arthritis Res. Ther. , vol.13 , pp. 234-243
    • Zhao, B.1    Ivashkiv, L.B.2
  • 58
    • 69949148448 scopus 로고    scopus 로고
    • Interferon regulatory factor-8 regulates bone metabolism by suppressing osteoclastogenesis
    • Zhao, B., M. Takami, A. Yamada, X. Wang, T. Koga, X. Hu, T. Tamura, K. Ozato, Y. Choi, L.B. Ivashkiv, et al. 2009. Interferon regulatory factor-8 regulates bone metabolism by suppressing osteoclastogenesis. Nat. Med. 15:1066-1071. http://dx.doi.org/10.1038/nm.2007
    • (2009) Nat. Med. , vol.15 , pp. 1066-1071
    • Zhao, B.1    Takami, M.2    Yamada, A.3    Wang, X.4    Koga, T.5    Hu, X.6    Tamura, T.7    Ozato, K.8    Choi, Y.9    Ivashkiv, L.B.10


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.