-
1
-
-
34250182404
-
Chemotherapy delivery issues in central nervous system malignancy: A reality check
-
Muldoon LL, Soussain C, Jahnke K, et al. Chemotherapy delivery issues in central nervous system malignancy: a reality check. J Clin Oncol. 2007; 25: 2295-2305.
-
(2007)
J Clin Oncol
, vol.25
, pp. 2295-2305
-
-
Muldoon, L.L.1
Soussain, C.2
Jahnke, K.3
-
2
-
-
0037161024
-
Chemotherapy in adult high-grade glioma: A systematic review and meta-analysis of individual patient data from 12 randomised trials
-
Stewart LA. Chemotherapy in adult high-grade glioma: a systematic review and meta-analysis of individual patient data from 12 randomised trials. Lancet. 2002; 359: 1011-1018.
-
(2002)
Lancet
, vol.359
, pp. 1011-1018
-
-
Stewart, L.A.1
-
3
-
-
34748884398
-
Chemoradiotherapy in malignant glioma: Standard of care and future directions
-
Stupp R, Hegi ME, Gilbert MR, Chakravarti A. Chemoradiotherapy in malignant glioma: standard of care and future directions. J Clin Oncol. 2007; 25: 4127-4136.
-
(2007)
J Clin Oncol
, vol.25
, pp. 4127-4136
-
-
Stupp, R.1
Hegi, M.E.2
Gilbert, M.R.3
Chakravarti, A.4
-
4
-
-
84865689994
-
New molecularly targeted therapies for glioblastoma multiforme
-
Polivka J, Jr., Polivka J, Rohan V, Topolcan O, Ferda J. New molecularly targeted therapies for glioblastoma multiforme. Anticancer Research. 2012; 32: 2935-2946.
-
(2012)
Anticancer Research
, vol.32
, pp. 2935-2946
-
-
Polivka Jr., J.1
Polivka, J.2
Rohan, V.3
Topolcan, O.4
Ferda, J.5
-
5
-
-
0034763901
-
Gadobenate dimeglumine-enhanced magnetic resonance imaging of intracranial metastases: Effect of dose on lesion detection and delineation
-
Schneider G, Kirchin MA, Pirovano G, et al. Gadobenate dimeglumine-enhanced magnetic resonance imaging of intracranial metastases: effect of dose on lesion detection and delineation. J Magn Reson Imaging. 2001; 14: 525-539.
-
(2001)
J Magn Reson Imaging
, vol.14
, pp. 525-539
-
-
Schneider, G.1
Kirchin, M.A.2
Pirovano, G.3
-
8
-
-
0028470454
-
Barriers to drug delivery in solid tumors
-
Jain RK. Barriers to drug delivery in solid tumors. Sci Am. 1994; 271: 58-65.
-
(1994)
Sci Am
, vol.271
, pp. 58-65
-
-
Jain, R.K.1
-
9
-
-
0028849284
-
Time-dependent behavior of interstitial fluid pressure in solid tumors: Implications for drug delivery
-
Netti PA, Baxter LT, Boucher Y, Skalak R, Jain RK. Time-dependent behavior of interstitial fluid pressure in solid tumors: implications for drug delivery. Cancer Res. 1995; 55: 5451-5458.
-
(1995)
Cancer Res
, vol.55
, pp. 5451-5458
-
-
Netti, P.A.1
Baxter, L.T.2
Boucher, Y.3
Skalak, R.4
Jain, R.K.5
-
10
-
-
11844254414
-
Normalization of tumor vasculature: An emerging concept in anti-angiogenic therapy
-
Jain RK. Normalization of tumor vasculature: an emerging concept in anti-angiogenic therapy. Science. 2005; 307: 58-62.
-
(2005)
Science
, vol.307
, pp. 58-62
-
-
Jain, R.K.1
-
11
-
-
84858067539
-
Insight into the cooperation of P-glycoprotein (ABCB1) and breast cancer resistance protein (ABCG2) at the bloodbrain barrier: A case study examining sorafenib efflux clearance
-
Agarwal S, Elmquist WF. Insight into the cooperation of P-glycoprotein (ABCB1) and breast cancer resistance protein (ABCG2) at the bloodbrain barrier: a case study examining sorafenib efflux clearance. Molecular pharmaceutics. 2012; 9: 678-684.
-
(2012)
Molecular Pharmaceutics
, vol.9
, pp. 678-684
-
-
Agarwal, S.1
Elmquist, W.F.2
-
12
-
-
84878280513
-
Examination of blood-brain barrier (BBB) integrity in a mouse brain tumor model
-
On NH, Mitchell R, Savant SD, Bachmeier CJ, Hatch GM, Miller DW. Examination of blood-brain barrier (BBB) integrity in a mouse brain tumor model. J Neurooncol. 2013; 11: 133-143.
-
(2013)
J Neurooncol
, vol.11
, pp. 133-143
-
-
On, N.H.1
Mitchell, R.2
Savant, S.D.3
Bachmeier, C.J.4
Hatch, G.M.5
Miller, D.W.6
-
13
-
-
33644763050
-
A model of human tumor dormancy: An angiogenic switch from the nonangiogenic phenotype
-
Naumov GN, Bender E, Zurakowski D, et al. A model of human tumor dormancy: an angiogenic switch from the nonangiogenic phenotype. J Natl Cancer Inst. 2006; 98: 316-325.
-
(2006)
J Natl Cancer Inst
, vol.98
, pp. 316-325
-
-
Naumov, G.N.1
Bender, E.2
Zurakowski, D.3
-
14
-
-
78651408563
-
Glioblastoma recurrence after cediranib therapy in patients: Lack of "rebound" revascularization as mode of escape
-
di Tomaso E, Snuderl M, Kamoun WS, et al. Glioblastoma recurrence after cediranib therapy in patients: lack of "rebound" revascularization as mode of escape. Cancer Res. 2011; 71: 19-28.
-
(2011)
Cancer Res
, vol.71
, pp. 19-28
-
-
Di Tomaso, E.1
Snuderl, M.2
Kamoun, W.S.3
-
15
-
-
79952740612
-
Anti-VEGF treatment reduces blood supply and increases tumor cell invasion in glioblastoma
-
Keunen O, Johansson M, Oudin A, et al. Anti-VEGF treatment reduces blood supply and increases tumor cell invasion in glioblastoma. Proc Natl Acad Sci USA. 2011; 108: 3749-3754.
-
(2011)
Proc Natl Acad Sci USA
, vol.108
, pp. 3749-3754
-
-
Keunen, O.1
Johansson, M.2
Oudin, A.3
-
16
-
-
78649303718
-
Microdialysis for assessing intratumoral drug disposition in brain cancers: A tool for rational drug development
-
Blakeley J, Portnow J. Microdialysis for assessing intratumoral drug disposition in brain cancers: a tool for rational drug development. Expert Opin Drug Metab Toxicol. 2010; 6: 1477-1491.
-
(2010)
Expert Opin Drug Metab Toxicol
, vol.6
, pp. 1477-1491
-
-
Blakeley, J.1
Portnow, J.2
-
17
-
-
67649133075
-
Novel drug delivery strategies in neurooncology
-
Bidros DS, Vogelbaum MA. Novel drug delivery strategies in neurooncology. Neurotherapeutics. 2009; 6: 539-546.
-
(2009)
Neurotherapeutics
, vol.6
, pp. 539-546
-
-
Bidros, D.S.1
Vogelbaum, M.A.2
-
18
-
-
70349408777
-
New strategies to deliver anticancer drugs to brain tumors
-
Laquintana V, Trapani A, Denora N, Wang F, Gallo JM, Trapani G. New strategies to deliver anticancer drugs to brain tumors. Expert Opin Drug Deliv. 2009; 6: 1017-1032.
-
(2009)
Expert Opin Drug Deliv
, vol.6
, pp. 1017-1032
-
-
Laquintana, V.1
Trapani, A.2
Denora, N.3
Wang, F.4
Gallo, J.M.5
Trapani, G.6
-
19
-
-
77954334041
-
Potential approaches for drug delivery to the brain: Past, present, and future
-
Soni V, Jain A, Khare P, Gulbake A, Jain SK. Potential approaches for drug delivery to the brain: past, present, and future. Crit Rev Ther Drug Carrier Syst. 2010; 27: 187-236.
-
(2010)
Crit Rev Ther Drug Carrier Syst
, vol.27
, pp. 187-236
-
-
Soni, V.1
Jain, A.2
Khare, P.3
Gulbake, A.4
Jain, S.K.5
-
20
-
-
20044366163
-
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma
-
Stupp R, Mason WP, van den Bent MJ, et al. Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma. N Engl J Med. 2005; 352: 987-996.
-
(2005)
N Engl J Med
, vol.352
, pp. 987-996
-
-
Stupp, R.1
Mason, W.P.2
Van Den Bent, M.J.3
-
21
-
-
57449121882
-
Getting into the brain: Approaches to enhance brain drug delivery
-
Patel MM, Goyal BR, Bhadada SV, Bhatt JS, Amin AF. Getting into the brain: approaches to enhance brain drug delivery. CNS Drugs. 2009; 23: 35-58.
-
(2009)
CNS Drugs
, vol.23
, pp. 35-58
-
-
Patel, M.M.1
Goyal, B.R.2
Bhadada, S.V.3
Bhatt, J.S.4
Amin, A.F.5
-
22
-
-
0035080458
-
Involvement of the multidrug resistance protein 3 in drug sensitivity and its expression in human glioma
-
Haga S, Hinoshita E, Ikezaki K, et al. Involvement of the multidrug resistance protein 3 in drug sensitivity and its expression in human glioma. Jpn J Cancer Res. 2001; 92: 211-219.
-
(2001)
Jpn J Cancer Res
, vol.92
, pp. 211-219
-
-
Haga, S.1
Hinoshita, E.2
Ikezaki, K.3
-
23
-
-
0042526079
-
Repetitive doxorubicin treatment of glioblastoma enhances the PGP expression - A special role for endothelial cells
-
Rittierodt M, Harada K. Repetitive doxorubicin treatment of glioblastoma enhances the PGP expression-a special role for endothelial cells. Exp Toxicol Pathol. 2003; 55: 39-44.
-
(2003)
Exp Toxicol Pathol
, vol.55
, pp. 39-44
-
-
Rittierodt, M.1
Harada, K.2
-
24
-
-
0026090890
-
The multidrug-resistance gene MDR1 is expressed in human glial tumors
-
Becker I, Becker KF, Meyermann R, Hollt V. The multidrug-resistance gene MDR1 is expressed in human glial tumors. Acta Neuropathol. 1991; 82: 516-519.
-
(1991)
Acta Neuropathol
, vol.82
, pp. 516-519
-
-
Becker, I.1
Becker, K.F.2
Meyermann, R.3
Hollt, V.4
-
25
-
-
84871598987
-
Function of the blood-brain barrier and restriction of drug delivery to invasive glioma cells: Findings in a orthotopic rat xenograft model of glioma
-
Agarwal S, Manchanda P, Vogelbaum MA, Ohlfest JR, Elmquist WF. Function of the blood-brain barrier and restriction of drug delivery to invasive glioma cells: findings in a orthotopic rat xenograft model of glioma. Drug Metabolism and Disposition: The Biological Fate of Chemicals. 2013; 41: 33-39.
-
(2013)
Drug Metabolism and Disposition: The Biological Fate of Chemicals
, vol.41
, pp. 33-39
-
-
Agarwal, S.1
Manchanda, P.2
Vogelbaum, M.A.3
Ohlfest, J.R.4
Elmquist, W.F.5
-
27
-
-
0027412117
-
Development of lipophilic anticancer agents for the treatment of brain tumors by the esterification of water-soluble chlorambucil
-
Genka S, Deutsch J, Shetty UH, et al. Development of lipophilic anticancer agents for the treatment of brain tumors by the esterification of water-soluble chlorambucil. Clinical and Experimental Metastasis. 1993; 11: 131-140.
-
(1993)
Clinical and Experimental Metastasis
, vol.11
, pp. 131-140
-
-
Genka, S.1
Deutsch, J.2
Shetty, U.H.3
-
28
-
-
33845784758
-
Blood-brain barrier delivery
-
Pardridge WM. Blood-brain barrier delivery. Drug Discovery Today. 2007; 12: 54-61.
-
(2007)
Drug Discovery Today
, vol.12
, pp. 54-61
-
-
Pardridge, W.M.1
-
30
-
-
82055206096
-
Prodrugs and endogenous transporters: Are they suitable tools for drug targeting into the central nervous system?
-
Pavan B, Dalpiaz A. Prodrugs and endogenous transporters: are they suitable tools for drug targeting into the central nervous system? Current Pharmaceutical Design. 2011; 17: 3560-3576.
-
(2011)
Current Pharmaceutical Design
, vol.17
, pp. 3560-3576
-
-
Pavan, B.1
Dalpiaz, A.2
-
32
-
-
84855597543
-
Reengineering biopharmaceuticals for targeted delivery across the blood-brain barrier
-
Pardridge WM, Boado RJ. Reengineering biopharmaceuticals for targeted delivery across the blood-brain barrier. Methods in Enzymology. 2012; 503: 269-292.
-
(2012)
Methods in Enzymology
, vol.503
, pp. 269-292
-
-
Pardridge, W.M.1
Boado, R.J.2
-
33
-
-
0031811052
-
Chemoprotection in anticancer therapy: The emerging role of amifostine (WR-2721)
-
Kurbacher CM, Mallmann PK. Chemoprotection in anticancer therapy: the emerging role of amifostine (WR-2721). Anticancer Research. 1998; 18: 2203-2210.
-
(1998)
Anticancer Research
, vol.18
, pp. 2203-2210
-
-
Kurbacher, C.M.1
Mallmann, P.K.2
-
34
-
-
43749101881
-
Effect of N-acetylcysteine route of administration on chemoprotection against cisplatin-induced toxicity in rat models
-
Dickey DT, Muldoon LL, Doolittle ND, Peterson DR, Kraemer DF, Neuwelt EA. Effect of N-acetylcysteine route of administration on chemoprotection against cisplatin-induced toxicity in rat models. Cancer Chemotherapy and Pharmacology. 2008; 62: 235-241.
-
(2008)
Cancer Chemotherapy and Pharmacology
, vol.62
, pp. 235-241
-
-
Dickey, D.T.1
Muldoon, L.L.2
Doolittle, N.D.3
Peterson, D.R.4
Kraemer, D.F.5
Neuwelt, E.A.6
-
35
-
-
68849096855
-
In vivo selection of hematopoietic progenitor cells and temozolomide dose intensification in rhesus macaques through lentiviral transduction with a drug resistance gene
-
Larochelle A, Choi U, Shou Y, et al. In vivo selection of hematopoietic progenitor cells and temozolomide dose intensification in rhesus macaques through lentiviral transduction with a drug resistance gene. The Journal of Clinical Investigation. 2009; 119: 1952-1963.
-
(2009)
The Journal of Clinical Investigation
, vol.119
, pp. 1952-1963
-
-
Larochelle, A.1
Choi, U.2
Shou, Y.3
-
36
-
-
34548159791
-
Pilot study of MDR1 gene transfer into hematopoietic stem cells and chemoprotection in metastatic breast cancer patients
-
Takahashi S, Aiba K, Ito Y, et al. Pilot study of MDR1 gene transfer into hematopoietic stem cells and chemoprotection in metastatic breast cancer patients. Cancer Science. 2007; 98: 1609-1616.
-
(2007)
Cancer Science
, vol.98
, pp. 1609-1616
-
-
Takahashi, S.1
Aiba, K.2
Ito, Y.3
-
37
-
-
13344285351
-
Improved outcome in adult B-cell acute lymphoblastic leukemia
-
Hoelzer D, Ludwig WD, Thiel E, et al. Improved outcome in adult B-cell acute lymphoblastic leukemia. Blood. 1996; 87: 495-508.
-
(1996)
Blood
, vol.87
, pp. 495-508
-
-
Hoelzer, D.1
Ludwig, W.D.2
Thiel, E.3
-
38
-
-
84859211271
-
CNS prophylaxis in diffuse large B-cell lymphoma: If, when, how and for whom?
-
Siegal T, Goldschmidt N. CNS prophylaxis in diffuse large B-cell lymphoma: if, when, how and for whom? Blood Reviews. 2012; 26: 97-106.
-
(2012)
Blood Reviews
, vol.26
, pp. 97-106
-
-
Siegal, T.1
Goldschmidt, N.2
-
39
-
-
0037115536
-
Radiation therapy oncology group S. Combination chemotherapy and radiotherapy for primary central nervous system lymphoma: Radiation therapy oncology group study 93-10
-
DeAngelis LM, Seiferheld W, Schold SC, Fisher B, Schultz CJ, Radiation Therapy Oncology Group S. Combination chemotherapy and radiotherapy for primary central nervous system lymphoma: Radiation Therapy Oncology Group Study 93-10. J Clin Oncol. 2002; 20: 4643-4648.
-
(2002)
J Clin Oncol
, vol.20
, pp. 4643-4648
-
-
Deangelis, L.M.1
Seiferheld, W.2
Schold, S.C.3
Fisher, B.4
Schultz, C.J.5
-
40
-
-
70350567171
-
High-dose cytarabine plus highdose methotrexate versus high-dose methotrexate alone in patients with primary CNS lymphoma: A randomised phase 2 trial
-
Ferreri AJ, Reni M, Foppoli M, et al. High-dose cytarabine plus highdose methotrexate versus high-dose methotrexate alone in patients with primary CNS lymphoma: a randomised phase 2 trial. Lancet. 2009; 374: 1512-1520.
-
(2009)
Lancet
, vol.374
, pp. 1512-1520
-
-
Ferreri, A.J.1
Reni, M.2
Foppoli, M.3
-
41
-
-
0032864504
-
Pharmacokinetics of methotrexate in the extracellular fluid of brain C6-glioma after intravenous infusion in rats
-
Dukic S, Heurtaux T, Kaltenbach ML, et al. Pharmacokinetics of methotrexate in the extracellular fluid of brain C6-glioma after intravenous infusion in rats. Pharm Res. 1999; 16: 1219-1225.
-
(1999)
Pharm Res
, vol.16
, pp. 1219-1225
-
-
Dukic, S.1
Heurtaux, T.2
Kaltenbach, M.L.3
-
42
-
-
0033863258
-
Influence of schedule of administration on methotrexate penetration in brain tumours
-
Dukic SF, Heurtaux T, Kaltenbach ML, Hoizey G, Lallemand A, Vistelle R. Influence of schedule of administration on methotrexate penetration in brain tumours. Eur J Cancer. 2000; 36: 1578-1584.
-
(2000)
Eur J Cancer
, vol.36
, pp. 1578-1584
-
-
Dukic, S.F.1
Heurtaux, T.2
Kaltenbach, M.L.3
Hoizey, G.4
Lallemand, A.5
Vistelle, R.6
-
43
-
-
0032696845
-
Rapid infusion of high-dose methotrexate resulting in enhanced penetration into cerebrospinal fluid and intensified tumor response in primary central nervous system lymphomas
-
Hiraga S, Arita N, Ohnishi T, et al. Rapid infusion of high-dose methotrexate resulting in enhanced penetration into cerebrospinal fluid and intensified tumor response in primary central nervous system lymphomas. J Neurosurg. 1999; 91: 221-230.
-
(1999)
J Neurosurg
, vol.91
, pp. 221-230
-
-
Hiraga, S.1
Arita, N.2
Ohnishi, T.3
-
44
-
-
57049117489
-
Effect of blood brain barrier permeability in recurrent high grade gliomas on the intratumoral pharmacokinetics of methotrexate: A microdialysis study
-
Blakeley JO, Olson J, Grossman SA, He X, Weingart J, Supko JG. Effect of blood brain barrier permeability in recurrent high grade gliomas on the intratumoral pharmacokinetics of methotrexate: a microdialysis study. J Neurooncol. 2009; 91: 51-58.
-
(2009)
J Neurooncol
, vol.91
, pp. 51-58
-
-
Blakeley, J.O.1
Olson, J.2
Grossman, S.A.3
He, X.4
Weingart, J.5
Supko, J.G.6
-
45
-
-
0032886269
-
Brain tumors: Complications of cerebral angiography accompanied by intraarterial chemotherapy
-
Gelman M, Chakeres DW, Newton HB. Brain tumors: complications of cerebral angiography accompanied by intraarterial chemotherapy. Radiology. 1999; 213: 135-140.
-
(1999)
Radiology
, vol.213
, pp. 135-140
-
-
Gelman, M.1
Chakeres, D.W.2
Newton, H.B.3
-
46
-
-
0343831896
-
Combined intraarterial carboplatin, intraarterial etoposide phosphate, and IV Cytoxan chemotherapy for progressive optic-hypothalamic gliomas in young children
-
Osztie E, Varallyay P, Doolittle ND, et al. Combined intraarterial carboplatin, intraarterial etoposide phosphate, and IV Cytoxan chemotherapy for progressive optic-hypothalamic gliomas in young children. AJNR Am J Neuroradiol. 2001; 22: 818-823.
-
(2001)
AJNR Am J Neuroradiol
, vol.22
, pp. 818-823
-
-
Osztie, E.1
Varallyay, P.2
Doolittle, N.D.3
-
47
-
-
0011311915
-
Toxicities related to intraarterial infusion of cisplatin and etoposide in patients with brain tumors
-
Tfayli A, Hentschel P, Madajewicz S, et al. Toxicities related to intraarterial infusion of cisplatin and etoposide in patients with brain tumors. J Neurooncol. 1999; 42: 73-77.
-
(1999)
J Neurooncol
, vol.42
, pp. 73-77
-
-
Tfayli, A.1
Hentschel, P.2
Madajewicz, S.3
-
48
-
-
70249106421
-
Blood-brain barrier disruption and intra-arterial methotrexate-based therapy for newly diagnosed primary CNS lymphoma: A multi-institutional experience
-
Angelov L, Doolittle ND, Kraemer DF, et al. Blood-brain barrier disruption and intra-arterial methotrexate-based therapy for newly diagnosed primary CNS lymphoma: a multi-institutional experience. J Clin Oncol. 2009; 27: 3503-3509.
-
(2009)
J Clin Oncol
, vol.27
, pp. 3503-3509
-
-
Angelov, L.1
Doolittle, N.D.2
Kraemer, D.F.3
-
49
-
-
0027272293
-
Cis-diamminedichloroplatinum (CDDP) therapy for brain metastasis of lung cancer. I. Distribution within the central nervous system after intravenous and intracarotid infusion
-
Nakagawa H, Fujita T, Izumoto S, et al. cis-diamminedichloroplatinum (CDDP) therapy for brain metastasis of lung cancer. I. Distribution within the central nervous system after intravenous and intracarotid infusion. J Neurooncol. 1993; 16: 61-67.
-
(1993)
J Neurooncol
, vol.16
, pp. 61-67
-
-
Nakagawa, H.1
Fujita, T.2
Izumoto, S.3
-
50
-
-
0031720748
-
Improving drug delivery to intracerebral tumor and surrounding brain in a rodent model: A comparison of osmotic versus bradykinin modification of the blood-brain and/or blood-tumor barriers
-
discussion 886-879
-
Kroll RA, Pagel MA, Muldoon LL, Roman-Goldstein S, Fiamengo SA, Neuwelt EA. Improving drug delivery to intracerebral tumor and surrounding brain in a rodent model: a comparison of osmotic versus bradykinin modification of the blood-brain and/or blood-tumor barriers. Neurosurgery. 1998; 43: 879-886. discussion 886-879.
-
(1998)
Neurosurgery
, vol.43
, pp. 879-886
-
-
Kroll, R.A.1
Pagel, M.A.2
Muldoon, L.L.3
Roman-Goldstein, S.4
Fiamengo, S.A.5
Neuwelt, E.A.6
-
51
-
-
0038399929
-
Facilitation of drug entry into the CNS via transient permeation of blood brain barrier: Laboratory and preliminary clinical evidence from bradykinin receptor agonist, Cereport
-
Borlongan CV, Emerich DF. Facilitation of drug entry into the CNS via transient permeation of blood brain barrier: laboratory and preliminary clinical evidence from bradykinin receptor agonist, Cereport. Brain Res Bull. 2003; 60: 297-306.
-
(2003)
Brain Res Bull
, vol.60
, pp. 297-306
-
-
Borlongan, C.V.1
Emerich, D.F.2
-
52
-
-
2942594011
-
Modulation of brain tumor capillaries for enhanced drug delivery selectively to brain tumor
-
Black KL, Ningaraj NS. Modulation of brain tumor capillaries for enhanced drug delivery selectively to brain tumor. Cancer Control: Journal of the Moffitt Cancer Center. 2004; 11: 165-173.
-
(2004)
Cancer Control: Journal of the Moffitt Cancer Center
, vol.11
, pp. 165-173
-
-
Black, K.L.1
Ningaraj, N.S.2
-
53
-
-
77049084023
-
Selective tumor blood-brain barrier opening with the kinin B2 receptor agonist [Phe(8)psi(CH(2)NH) Arg(9)]-BK in a F98 glioma rat model: An MRI study
-
Cote J, Savard M, Bovenzi V, et al. Selective tumor blood-brain barrier opening with the kinin B2 receptor agonist [Phe(8)psi(CH(2)NH) Arg(9)]-BK in a F98 glioma rat model: an MRI study. Neuropeptides. 2010; 44: 177-185.
-
(2010)
Uropeptides
, pp. 177-185
-
-
Cote, J.1
Savard, M.2
Bovenzi, V.3
-
54
-
-
78449242559
-
Novel magnetic/ultrasound focusing system enhances nanoparticle drug delivery for glioma treatment
-
Chen PY, Liu HL, Hua MY, et al. Novel magnetic/ultrasound focusing system enhances nanoparticle drug delivery for glioma treatment. Neuro Oncol. 2010; 12: 1050-1060.
-
(2010)
Neuro Oncol
, vol.12
, pp. 1050-1060
-
-
Chen, P.Y.1
Liu, H.L.2
Hua, M.Y.3
-
55
-
-
77951477367
-
Blood-brain barrier disruption with focused ultrasound enhances delivery of chemotherapeutic drugs for glioblastoma treatment
-
Liu HL, Hua MY, Chen PY, et al. Blood-brain barrier disruption with focused ultrasound enhances delivery of chemotherapeutic drugs for glioblastoma treatment. Radiology. 2010; 255: 415-425.
-
(2010)
Radiology
, vol.255
, pp. 415-425
-
-
Liu, H.L.1
Hua, M.Y.2
Chen, P.Y.3
-
56
-
-
79954507590
-
Targeted drug delivery across the blood-brain barrier using ultrasound technique
-
Deng CX. Targeted drug delivery across the blood-brain barrier using ultrasound technique. Therapeutic Delivery. 2010; 1: 819-848.
-
(2010)
Therapeutic Delivery
, vol.1
, pp. 819-848
-
-
Deng, C.X.1
-
57
-
-
0034028065
-
Vivo assessment of the window of barrier opening after osmotic blood-brain barrier disruption in humans
-
Siegal T, Rubinstein R, Bokstein F, et al. In vivo assessment of the window of barrier opening after osmotic blood-brain barrier disruption in humans. J Neurosurg. 2000; 92: 599-605.
-
(2000)
Neurosurg
, vol.92
, pp. 599-605
-
-
Siegal, T.1
Rubinstein, R.2
Bokstein, F.3
-
58
-
-
0034051370
-
Pharmacokinetics of methotrexate in cerebrospinal fluid and serum after osmotic blood-brain barrier disruption in patients with brain lymphoma
-
Zylber-Katz E, Gomori JM, Schwartz A, Lossos A, Bokstein F, Siegal T. Pharmacokinetics of methotrexate in cerebrospinal fluid and serum after osmotic blood-brain barrier disruption in patients with brain lymphoma. Clin Pharmacol Ther. 2000; 67: 631-641.
-
(2000)
Clin Pharmacol Ther
, vol.67
, pp. 631-641
-
-
Zylber-Katz, E.1
Gomori, J.M.2
Schwartz, A.3
Lossos, A.4
Bokstein, F.5
Siegal, T.6
-
59
-
-
34247151602
-
Seizure-promoting effect of blood-brain barrier disruption
-
Marchi N, Angelov L, Masaryk T, et al. Seizure-promoting effect of blood-brain barrier disruption. Epilepsia. 2007; 48: 732-742.
-
(2007)
Epilepsia
, vol.48
, pp. 732-742
-
-
Marchi, N.1
Angelov, L.2
Masaryk, T.3
-
60
-
-
80052746484
-
Inconsistent blood brain barrier disruption by intraarterial mannitol in rabbits: Implications for chemotherapy
-
Joshi S, Ergin A, Wang M, et al. Inconsistent blood brain barrier disruption by intraarterial mannitol in rabbits: implications for chemotherapy. J Neurooncol. 2011; 104: 11-19.
-
(2011)
J Neurooncol
, vol.104
, pp. 11-19
-
-
Joshi, S.1
Ergin, A.2
Wang, M.3
-
61
-
-
84857061967
-
The feasibility of real-time in vivo optical detection of blood-brain barrier disruption with indocyanine green
-
Ergin A, Wang M, Zhang JY, et al. The feasibility of real-time in vivo optical detection of blood-brain barrier disruption with indocyanine green. J Neurooncol. 2012; 106: 551-560.
-
(2012)
J Neurooncol
, vol.106
, pp. 551-560
-
-
Ergin, A.1
Wang, M.2
Zhang, J.Y.3
-
62
-
-
0029592056
-
Pharmacological blood-brain barrier modification for selective drug delivery
-
Cloughesy TF, Black KL. Pharmacological blood-brain barrier modification for selective drug delivery. J Neurooncol. 1995; 26: 125-132.
-
(1995)
J Neurooncol
, vol.26
, pp. 125-132
-
-
Cloughesy, T.F.1
Black, K.L.2
-
63
-
-
84864700861
-
Brain-blood barrier breakdownand pro-inflammatorymediators in neonate rats submitted meningitis by Streptococcus pneumoniae
-
Barichello T, Fagundes GD, Generoso JS, et al. Brain-blood barrier breakdownand pro-inflammatorymediators in neonate rats submitted meningitis by Streptococcus pneumoniae. Brain Research. 2012; 1471: 162-168.
-
(2012)
Brain Research
, vol.1471
, pp. 162-168
-
-
Barichello, T.1
Fagundes, G.D.2
Generoso, J.S.3
-
64
-
-
34948909646
-
Human TH17 lymphocytes promote blood-brain barrier disruption and central nervous system inflammation
-
Kebir H, Kreymborg K, Ifergan I, et al. Human TH17 lymphocytes promote blood-brain barrier disruption and central nervous system inflammation. Nature Medicine. 2007; 13: 1173-1175.
-
(2007)
Nature Medicine
, vol.13
, pp. 1173-1175
-
-
Kebir, H.1
Kreymborg, K.2
Ifergan, I.3
-
65
-
-
0030296346
-
Ntrolled modulation of BBB permeability using the bradykinin agonist, RMP-7
-
Bartus RT, Elliott PJ, Dean RL, et al. Controlled modulation of BBB permeability using the bradykinin agonist, RMP-7. Exp Neurol. 1996; 142: 14-28.
-
(1996)
P Neurol
, vol.142
, pp. 14-28
-
-
Bartus, R.T.1
Elliott, P.J.2
Dean, R.L.3
-
66
-
-
0032189111
-
A phase i study of intravenous RMP-7 with carboplatin in patients with progression of malignant glioma
-
Ford J, Osborn C, Barton T, Bleehen NM. A phase I study of intravenous RMP-7 with carboplatin in patients with progression of malignant glioma. Eur J Cancer. 1998; 34: 1807-1811.
-
(1998)
Eur J Cancer
, vol.34
, pp. 1807-1811
-
-
Ford, J.1
Osborn, C.2
Barton, T.3
Bleehen, N.M.4
-
68
-
-
77953925499
-
Site-specific opening of the blood-brain barrier
-
Madsen SJ, Hirschberg H. Site-specific opening of the blood-brain barrier. Journal of Biophotonics. 2010; 3: 356-367.
-
(2010)
Journal of Biophotonics
, vol.3
, pp. 356-367
-
-
Madsen, S.J.1
Hirschberg, H.2
-
69
-
-
84863952172
-
Temporary disruption of the blood-brain barrier by use of ultrasound and microbubbles: Safety and efficacy evaluation in rhesus macaques
-
McDannold N, Arvanitis CD, Vykhodtseva N, Livingstone MS. Temporary disruption of the blood-brain barrier by use of ultrasound and microbubbles: safety and efficacy evaluation in rhesus macaques. Cancer Res. 2012; 72: 3652-3663.
-
(2012)
Cancer Res
, vol.72
, pp. 3652-3663
-
-
McDannold, N.1
Arvanitis, C.D.2
Vykhodtseva, N.3
Livingstone, M.S.4
-
70
-
-
0034876083
-
Noninvasive MR imaging-guided focal opening of the blood-brain barrier in rabbits
-
Hynynen K, McDannold N, Vykhodtseva N, Jolesz FA. Noninvasive MR imaging-guided focal opening of the blood-brain barrier in rabbits. Radiology. 2001; 220: 640-646.
-
(2001)
Radiology
, vol.220
, pp. 640-646
-
-
Hynynen, K.1
McDannold, N.2
Vykhodtseva, N.3
Jolesz, F.A.4
-
71
-
-
34547121440
-
Targeted delivery of doxorubicin to the rat brain at therapeutic levels using MRI-guided focused ultrasound
-
Treat LH, McDannold N, Vykhodtseva N, Zhang Y, Tam K, Hynynen K. Targeted delivery of doxorubicin to the rat brain at therapeutic levels using MRI-guided focused ultrasound. Int J Cancer. 2007; 121: 901-907.
-
(2007)
Int J Cancer
, vol.121
, pp. 901-907
-
-
Treat, L.H.1
McDannold, N.2
Vykhodtseva, N.3
Zhang, Y.4
Tam, K.5
Hynynen, K.6
-
72
-
-
33746851261
-
Noninvasive localized delivery of Herceptin to the mouse brain by MRI-guided focused ultrasound-induced blood-brain barrier disruption
-
Kinoshita M, McDannold N, Jolesz FA, Hynynen K. Noninvasive localized delivery of Herceptin to the mouse brain by MRI-guided focused ultrasound-induced blood-brain barrier disruption. Proc Natl Acad Sci USA. 2006; 103: 11719-11723.
-
(2006)
Proc Natl Acad Sci USA
, vol.103
, pp. 11719-11723
-
-
Kinoshita, M.1
McDannold, N.2
Jolesz, F.A.3
Hynynen, K.4
-
73
-
-
80055109177
-
Concurrent blood-brain barrier opening and local drug delivery using drug-carrying microbubbles and focused ultrasound for brain glioma treatment
-
Ting CY, Fan CH, Liu HL, et al. Concurrent blood-brain barrier opening and local drug delivery using drug-carrying microbubbles and focused ultrasound for brain glioma treatment. Biomaterials. 2012; 33: 704-712.
-
(2012)
Biomaterials
, vol.33
, pp. 704-712
-
-
Ting, C.Y.1
Fan, C.H.2
Liu, H.L.3
-
74
-
-
0036627484
-
Drug transport to the brain: Key roles for the efflux pump P-glycoprotein in the blood-brain barrier
-
Demeule M, Regina A, Jodoin J, et al. Drug transport to the brain: key roles for the efflux pump P-glycoprotein in the blood-brain barrier. Vascular Pharmacology. 2002; 38: 339-348.
-
(2002)
Vascular Pharmacology
, vol.38
, pp. 339-348
-
-
Demeule, M.1
Regina, A.2
Jodoin, J.3
-
75
-
-
25144450046
-
Apical/basolateral surface expression of drug transporters and its role in vectorial drug transport
-
Ito K, Suzuki H, Horie T, Sugiyama Y. Apical/basolateral surface expression of drug transporters and its role in vectorial drug transport. Pharm Res. 2005; 22: 1559-1577.
-
(2005)
Pharm Res
, vol.22
, pp. 1559-1577
-
-
Ito, K.1
Suzuki, H.2
Horie, T.3
Sugiyama, Y.4
-
76
-
-
58949089716
-
A MDR1 (ABCB1) gene single nucleotide polymorphism predicts outcome of temozolomide treatment in glioblastoma patients. Annals of Oncology
-
Schaich M, Kestel L, Pfirrmann M, et al. A MDR1 (ABCB1) gene single nucleotide polymorphism predicts outcome of temozolomide treatment in glioblastoma patients. Annals of Oncology: Official Journal of the European Society for Medical Oncology/ESMO. 2009; 20: 175-181.
-
(2009)
Official Journal of the European Society for Medical Oncology/ESMO
, vol.20
, pp. 175-181
-
-
Schaich, M.1
Kestel, L.2
Pfirrmann, M.3
-
77
-
-
0345724724
-
The MRP family of drug efflux pumps
-
Kruh GD, Belinsky MG. The MRP family of drug efflux pumps. Oncogene. 2003; 22: 7537-7552.
-
(2003)
Oncogene
, vol.22
, pp. 7537-7552
-
-
Kruh, G.D.1
Belinsky, M.G.2
-
78
-
-
0035399586
-
Expression of multidrug-resistance P-glycoprotein (MDR1) in human brain tumors
-
Demeule M, Shedid D, Beaulieu E, et al. Expression of multidrug-resistance P-glycoprotein (MDR1) in human brain tumors. Int J Cancer. 2001; 93: 62-66.
-
(2001)
Int J Cancer
, vol.93
, pp. 62-66
-
-
Demeule, M.1
Shedid, D.2
Beaulieu, E.3
-
79
-
-
0032678857
-
Expression of the multidrug-resistance P-glycoprotein (Pgp, MDR-1) by endothelial cells of the neovasculature in central nervous system tumors
-
Sawada T, Kato Y, Sakayori N, Takekawa Y, Kobayashi M. Expression of the multidrug-resistance P-glycoprotein (Pgp, MDR-1) by endothelial cells of the neovasculature in central nervous system tumors. Brain Tumor Pathology. 1999; 16: 23-27.
-
(1999)
Brain Tumor Pathology
, vol.16
, pp. 23-27
-
-
Sawada, T.1
Kato, Y.2
Sakayori, N.3
Takekawa, Y.4
Kobayashi, M.5
-
81
-
-
84867417474
-
Active efflux of Dasatinib from the brain limits efficacy against murine glioblastoma: Broad implications for the clinical use of molecularly targeted agents
-
Agarwal S, Mittapalli RK, Zellmer DM, et al. Active efflux of Dasatinib from the brain limits efficacy against murine glioblastoma: broad implications for the clinical use of molecularly targeted agents. Molecular Cancer Therapeutics. 2012; 11: 2183-2192.
-
(2012)
Molecular Cancer Therapeutics
, vol.11
, pp. 2183-2192
-
-
Agarwal, S.1
Mittapalli, R.K.2
Zellmer, D.M.3
-
82
-
-
80053435892
-
Delivery of molecularly targeted therapy to malignant glioma, a disease of the whole brain
-
Agarwal S, Sane R, Oberoi R, Ohlfest JR, Elmquist WF. Delivery of molecularly targeted therapy to malignant glioma, a disease of the whole brain. Expert Reviews in Molecular Medicine. 2011; 13: e17.
-
(2011)
Expert Reviews in Molecular Medicine
, vol.13
-
-
Agarwal, S.1
Sane, R.2
Oberoi, R.3
Ohlfest, J.R.4
Elmquist, W.F.5
-
83
-
-
0030738096
-
Modulation and prevention of multidrug resistance by inhibitors of P-glycoprotein
-
Sikic BI, Fisher GA, Lum BL, Halsey J, Beketic-Oreskovic L, Chen G. Modulation and prevention of multidrug resistance by inhibitors of P-glycoprotein. Cancer Chemotherapy and Pharmacology. 1997; 40(Suppl): S13-19.
-
(1997)
Cancer Chemotherapy and Pharmacology
, vol.40
, Issue.SUPPL.
-
-
Sikic, B.I.1
Fisher, G.A.2
Lum, B.L.3
Halsey, J.4
Beketic-Oreskovic, L.5
Chen, G.6
-
84
-
-
3242777026
-
Modulation of the blood-brain barrier in oncology: Therapeutic opportunities for the treatment of brain tumours?
-
Kemper EM, Boogerd W, Thuis I, Beijnen JH, van Tellingen O. Modulation of the blood-brain barrier in oncology: therapeutic opportunities for the treatment of brain tumours?. Cancer Treatment Reviews. 2004; 30: 415-423.
-
(2004)
Cancer Treatment Reviews
, vol.30
, pp. 415-423
-
-
Kemper, E.M.1
Boogerd, W.2
Thuis, I.3
Beijnen, J.H.4
Van Tellingen, O.5
-
85
-
-
80053538365
-
Breast cancer resistance protein and P-glycoprotein in brain cancer: Two gatekeepers team up
-
Agarwal S, Hartz AM, Elmquist WF, Bauer B. Breast cancer resistance protein and P-glycoprotein in brain cancer: two gatekeepers team up. Current Pharmaceutical Design. 2011; 17: 2793-2802.
-
(2011)
Current Pharmaceutical Design
, vol.17
, pp. 2793-2802
-
-
Agarwal, S.1
Hartz, A.M.2
Elmquist, W.F.3
Bauer, B.4
-
86
-
-
60749134708
-
Effective transvascular delivery of nanoparticles across the blood-brain tumor barrier into malignant glioma cells
-
Sarin H, Kanevsky AS, Wu H, et al. Effective transvascular delivery of nanoparticles across the blood-brain tumor barrier into malignant glioma cells. Journal of Translational Medicine. 2008; 6: 80.
-
(2008)
Journal of Translational Medicine
, vol.6
, pp. 80
-
-
Sarin, H.1
Kanevsky, A.S.2
Wu, H.3
-
88
-
-
79956069265
-
Current advances in delivery of biotherapeutics across the blood-brain barrier
-
Rajadhyaksha M, Boyden T, Liras J, El-Kattan A, Brodfuehrer J. Current advances in delivery of biotherapeutics across the blood-brain barrier. Current Drug Discovery Technologies. 2011; 8: 87-101.
-
(2011)
Current Drug Discovery Technologies
, vol.8
, pp. 87-101
-
-
Rajadhyaksha, M.1
Boyden, T.2
Liras, J.3
El-Kattan, A.4
Brodfuehrer, J.5
-
89
-
-
84859958800
-
Nanotechnological advances for the delivery of CNS therapeutics
-
Wong HL, Wu XY, Bendayan R. Nanotechnological advances for the delivery of CNS therapeutics. Advanced Drug Delivery Reviews. 2012; 64: 686-700.
-
(2012)
Advanced Drug Delivery Reviews
, vol.64
, pp. 686-700
-
-
Wong, H.L.1
Wu, X.Y.2
Bendayan, R.3
-
90
-
-
67650727594
-
Physiologic upper limit of pore size in the blood-tumor barrier of malignant solid tumors
-
Sarin H, Kanevsky AS, Wu H, et al. Physiologic upper limit of pore size in the blood-tumor barrier of malignant solid tumors. Journal of Translational Medicine. 2009; 7: 51.
-
(2009)
Journal of Translational Medicine
, vol.7
, pp. 51
-
-
Sarin, H.1
Kanevsky, A.S.2
Wu, H.3
-
91
-
-
52749092565
-
PEGylation: An approach for drug delivery. A review
-
Jain A, Jain SK. PEGylation: an approach for drug delivery. A review. Crit Rev Ther Drug Carrier Syst. 2008; 25: 403-447.
-
(2008)
Crit Rev Ther Drug Carrier Syst
, vol.25
, pp. 403-447
-
-
Jain, A.1
Jain, S.K.2
-
92
-
-
0030447660
-
Brain drug delivery of small molecules using immunoliposomes
-
Huwyler J, Wu D, Pardridge WM. Brain drug delivery of small molecules using immunoliposomes. Proc Natl Acad Sci USA. 1996; 93: 14164-14169.
-
(1996)
Proc Natl Acad Sci USA
, vol.93
, pp. 14164-14169
-
-
Huwyler, J.1
Wu, D.2
Pardridge, W.M.3
-
95
-
-
0030930364
-
Drug targeting of a peptide radiopharmaceutical through the primate blood-brain barrier in vivo with a monoclonal antibody to the human insulin receptor
-
Wu D, Yang J, Pardridge WM. Drug targeting of a peptide radiopharmaceutical through the primate blood-brain barrier in vivo with a monoclonal antibody to the human insulin receptor. The Journal of Clinical Investigation. 1997; 100: 1804-1812.
-
(1997)
The Journal of Clinical Investigation
, vol.100
, pp. 1804-1812
-
-
Wu, D.1
Yang, J.2
Pardridge, W.M.3
-
96
-
-
29244489232
-
Epidermal growth factor receptor-targeted immunoliposomes significantly enhance the efficacy of multiple anticancer drugs in vivo
-
Mamot C, Drummond DC, Noble CO, et al. Epidermal growth factor receptor-targeted immunoliposomes significantly enhance the efficacy of multiple anticancer drugs in vivo. Cancer Res. 2005; 65: 11631-11638.
-
(2005)
Cancer Res
, vol.65
, pp. 11631-11638
-
-
Mamot, C.1
Drummond, D.C.2
Noble, C.O.3
-
97
-
-
0033520487
-
In vivo protein transduction: Delivery of a biologically active protein into the mouse
-
Schwarze SR, Ho A, Vocero-Akbani A, Dowdy SF. In vivo protein transduction: delivery of a biologically active protein into the mouse. Science. 1999; 285: 1569-1572.
-
(1999)
Science
, vol.285
, pp. 1569-1572
-
-
Schwarze, S.R.1
Ho, A.2
Vocero-Akbani, A.3
Dowdy, S.F.4
-
98
-
-
38549180565
-
Biologically active core/shell nanoparticles self-assembled from cholesterol-terminated PEG-TAT for drug delivery across the blood-brain barrier
-
Liu L, Guo K, Lu J, et al. Biologically active core/shell nanoparticles self-assembled from cholesterol-terminated PEG-TAT for drug delivery across the blood-brain barrier. Biomaterials. 2008; 29: 1509-1517.
-
(2008)
Biomaterials
, vol.29
, pp. 1509-1517
-
-
Liu, L.1
Guo, K.2
Lu, J.3
-
99
-
-
18744413936
-
Polysorbate-stabilized solid lipid nanoparticles as colloidal carriers for intravenous targeting of drugs to the brain: Comparison of plasma protein adsorption patterns
-
Goppert TM, Muller RH. Polysorbate-stabilized solid lipid nanoparticles as colloidal carriers for intravenous targeting of drugs to the brain: comparison of plasma protein adsorption patterns. Journal of Drug Targeting. 2005; 13: 179-187.
-
(2005)
Journal of Drug Targeting
, vol.13
, pp. 179-187
-
-
Goppert, T.M.1
Muller, R.H.2
-
100
-
-
0037335187
-
Direct evidence that polysorbate-80-coated poly(butylcyanoacrylate) nanoparticles deliver drugs to the CNS via specific mechanisms requiring prior binding of drug to the nanoparticles
-
Kreuter J, Ramge P, Petrov V, et al. Direct evidence that polysorbate-80-coated poly(butylcyanoacrylate) nanoparticles deliver drugs to the CNS via specific mechanisms requiring prior binding of drug to the nanoparticles. Pharm Res. 2003; 20: 409-416.
-
(2003)
Pharm Res
, vol.20
, pp. 409-416
-
-
Kreuter, J.1
Ramge, P.2
Petrov, V.3
-
101
-
-
33646796753
-
Covalent linkage of apolipoprotein e to albumin nanoparticles strongly enhances drug transport into the brain
-
Michaelis K, Hoffmann MM, Dreis S, et al. Covalent linkage of apolipoprotein e to albumin nanoparticles strongly enhances drug transport into the brain. The Journal of Pharmacology and Experimental Therapeutics. 2006; 317: 1246-1253.
-
(2006)
The Journal of Pharmacology and Experimental Therapeutics
, vol.317
, pp. 1246-1253
-
-
Michaelis, K.1
Hoffmann, M.M.2
Dreis, S.3
-
102
-
-
84867302514
-
A novel magnetic nanoparticle drug carrier for enhanced cancer chemotherapy
-
Chao X, Zhang Z, Guo L, et al. A novel magnetic nanoparticle drug carrier for enhanced cancer chemotherapy. PloS one. 2012; 7: e40388.
-
(2012)
PloS One
, vol.7
-
-
Chao, X.1
Zhang, Z.2
Guo, L.3
-
104
-
-
79951868441
-
Doxorubicin loaded magnetic polymersomes: Theranostic nanocarriers for MR imaging and magneto-chemotherapy
-
Sanson C, Diou O, Thevenot J, et al. Doxorubicin loaded magnetic polymersomes: theranostic nanocarriers for MR imaging and magneto-chemotherapy. ACS nano. 2011; 5: 1122-1140.
-
(2011)
ACS Nano
, vol.5
, pp. 1122-1140
-
-
Sanson, C.1
Diou, O.2
Thevenot, J.3
-
106
-
-
80052831943
-
Exosome nanotechnology: An emerging paradigm shift in drug delivery: Exploitation of exosome nanovesicles for systemic in vivo delivery of RNAi heralds new horizons for drug delivery across biological barriers
-
Lakhal S, Wood MJ. Exosome nanotechnology: an emerging paradigm shift in drug delivery: exploitation of exosome nanovesicles for systemic in vivo delivery of RNAi heralds new horizons for drug delivery across biological barriers. BioEssays: News and Reviews in Molecular, Cellular and Developmental Biology. 2011; 33: 737-741.
-
(2011)
BioEssays: News and Reviews in Molecular, Cellular and Developmental Biology
, vol.33
, pp. 737-741
-
-
Lakhal, S.1
Wood, M.J.2
-
107
-
-
34249302620
-
Exosome-mediated transfer of mRNAs and microRNAs is a novel mechanism of genetic exchange between cells
-
Valadi H, Ekstrom K, Bossios A, Sjostrand M, Lee JJ, Lotvall JO. Exosome-mediated transfer of mRNAs and microRNAs is a novel mechanism of genetic exchange between cells. Nature Cell Biology. 2007; 9: 654-659.
-
(2007)
Nature Cell Biology
, vol.9
, pp. 654-659
-
-
Valadi, H.1
Ekstrom, K.2
Bossios, A.3
Sjostrand, M.4
Lee, J.J.5
Lotvall, J.O.6
-
109
-
-
79953858598
-
Delivery of siRNA to the mouse brain by systemic injection of targeted exosomes
-
Alvarez-Erviti L, Seow Y, Yin H, Betts C, Lakhal S, Wood MJ. Delivery of siRNA to the mouse brain by systemic injection of targeted exosomes. Nature Biotechnology. 2011; 29: 341-345.
-
(2011)
Nature Biotechnology
, vol.29
, pp. 341-345
-
-
Alvarez-Erviti, L.1
Seow, Y.2
Yin, H.3
Betts, C.4
Lakhal, S.5
Wood, M.J.6
-
110
-
-
76549260925
-
Isolation and cultivation of human keratinocytes from skin or plucked hair for the generation of induced pluripotent stem cells
-
Aasen T, Izpisua Belmonte JC. Isolation and cultivation of human keratinocytes from skin or plucked hair for the generation of induced pluripotent stem cells. Nature Protocols. 2010; 5: 371-382.
-
(2010)
Nature Protocols
, vol.5
, pp. 371-382
-
-
Aasen, T.1
Izpisua Belmonte, J.C.2
-
112
-
-
33644787355
-
Gliadel wafer in initial surgery for malignant glioma: Long-term follow-up of a multicenter controlled trial
-
discussion 275
-
Westphal M, Ram Z, Riddle V, Hilt D, Bortey E, Executive Committee of the Gliadel Study G. Gliadel wafer in initial surgery for malignant glioma: long-term follow-up of a multicenter controlled trial. Acta Neurochirurgica. 2006; 148: 269-275. discussion 275.
-
(2006)
Acta Neurochirurgica
, vol.148
, pp. 269-275
-
-
Westphal, M.1
Ram, Z.2
Riddle, V.3
Hilt, D.4
Bortey, E.5
-
113
-
-
0026100939
-
Interstitial chemotherapy with drug polymer implants for the treatment of recurrent gliomas
-
Brem H, Mahaley MS, Jr., Vick NA, et al. Interstitial chemotherapy with drug polymer implants for the treatment of recurrent gliomas. J Neurosurg. 1991; 74: 441-446.
-
(1991)
J Neurosurg
, vol.74
, pp. 441-446
-
-
Brem, H.1
Mahaley Jr., M.S.2
Vick, N.A.3
-
114
-
-
37649010802
-
Clinical experience with alpha-particle emitting 211At: Treatment of recurrent brain tumor patients with 211At-labeled chimeric antitenascin monoclonal antibody 81C6
-
Zalutsky MR, Reardon DA, Akabani G, et al. Clinical experience with alpha-particle emitting 211At: treatment of recurrent brain tumor patients with 211At-labeled chimeric antitenascin monoclonal antibody 81C6. Journal of Nuclear Medicine: Official Publication, Society of Nuclear Medicine. 2008; 49: 30-38.
-
(2008)
Journal of Nuclear Medicine: Official Publication, Society of Nuclear Medicine
, vol.49
, pp. 30-38
-
-
Zalutsky, M.R.1
Reardon, D.A.2
Akabani, G.3
-
115
-
-
20444411528
-
Intratumoral delivery of mitoxantrone in association with 90-Y radioimmunotherapy (RIT) in recurrent glioblastoma
-
Boiardi A, Bartolomei M, Silvani A, et al. Intratumoral delivery of mitoxantrone in association with 90-Y radioimmunotherapy (RIT) in recurrent glioblastoma. J Neurooncol. 2005; 72: 125-131.
-
(2005)
J Neurooncol
, vol.72
, pp. 125-131
-
-
Boiardi, A.1
Bartolomei, M.2
Silvani, A.3
-
116
-
-
1442282498
-
Convection-enhanced delivery of paclitaxel for the treatment of recurrent malignant glioma: A phase I/II clinical study
-
Lidar Z, Mardor Y, Jonas T, et al. Convection-enhanced delivery of paclitaxel for the treatment of recurrent malignant glioma: a phase I/II clinical study. J Neurosurg. 2004; 100: 472-479.
-
(2004)
J Neurosurg
, vol.100
, pp. 472-479
-
-
Lidar, Z.1
Mardor, Y.2
Jonas, T.3
-
117
-
-
33947547455
-
Direct intracerebral delivery of cintredekin besudotox (IL13-PE38QQR) in recurrent malignant glioma: A report by the Cintredekin Besudotox Intraparenchymal Study Group
-
Kunwar S, Prados MD, Chang SM, et al. Direct intracerebral delivery of cintredekin besudotox (IL13-PE38QQR) in recurrent malignant glioma: a report by the Cintredekin Besudotox Intraparenchymal Study Group. J Clin Oncol. 2007; 25: 837-844.
-
(2007)
J Clin Oncol
, vol.25
, pp. 837-844
-
-
Kunwar, S.1
Prados, M.D.2
Chang, S.M.3
-
118
-
-
52949098192
-
Intracerebral infusion of an EGFR-targeted toxin in recurrent malignant brain tumors
-
Sampson JH, Akabani G, Archer GE, et al. Intracerebral infusion of an EGFR-targeted toxin in recurrent malignant brain tumors. Neuro Oncol. 2008; 10: 320-329.
-
(2008)
Neuro Oncol
, vol.10
, pp. 320-329
-
-
Sampson, J.H.1
Akabani, G.2
Archer, G.E.3
-
119
-
-
84855546609
-
Convection-enhanced delivery of therapeutic agents into the brain
-
Vinken, PJ, Bruyn, GW ed
-
Vogelbaum MA, Iannotti CA. Convection-enhanced delivery of therapeutic agents into the brain. Vinken, PJ, Bruyn, GW ed. Handbook of Clinical Neurology. 2012; 104: 355-362.
-
(2012)
Handbook of Clinical Neurology
, vol.104
, pp. 355-362
-
-
Vogelbaum, M.A.1
Iannotti, C.A.2
-
120
-
-
0029884848
-
Chemotherapeutic drugs released from polymers: Distribution of 1,3-bis(2-chloroethyl)- 1-nitrosourea in the rat brain
-
Fung LK, Shin M, Tyler B, Brem H, Saltzman WM. Chemotherapeutic drugs released from polymers: distribution of 1,3-bis(2-chloroethyl)- 1-nitrosourea in the rat brain. Pharm Res. 1996; 13: 671-682.
-
(1996)
Pharm Res
, vol.13
, pp. 671-682
-
-
Fung, L.K.1
Shin, M.2
Tyler, B.3
Brem, H.4
Saltzman, W.M.5
-
121
-
-
0029045339
-
Distribution of nerve growth factor following direct delivery to brain interstitium
-
Krewson CE, Klarman ML, Saltzman WM. Distribution of nerve growth factor following direct delivery to brain interstitium. Brain Research. 1995; 680: 196-206.
-
(1995)
Brain Research
, vol.680
, pp. 196-206
-
-
Krewson, C.E.1
Klarman, M.L.2
Saltzman, W.M.3
-
122
-
-
0034043076
-
The role of interstitial BCNU chemotherapy in the treatment of malignant glioma
-
Engelhard HH. The role of interstitial BCNU chemotherapy in the treatment of malignant glioma. Surgical Neurology. 2000; 53: 458-464.
-
(2000)
Surgical Neurology
, vol.53
, pp. 458-464
-
-
Engelhard, H.H.1
-
123
-
-
33747175422
-
Convection-enhanced delivery of therapeutics for brain disease, and its optimization
-
Raghavan R, Brady ML, Rodriguez-Ponce MI, Hartlep A, Pedain C, Sampson JH. Convection-enhanced delivery of therapeutics for brain disease, and its optimization. Neurosurgical Focus. 2006; 20: E12.
-
(2006)
Neurosurgical Focus
, vol.20
-
-
Raghavan, R.1
Brady, M.L.2
Rodriguez-Ponce, M.I.3
Hartlep, A.4
Pedain, C.5
Sampson, J.H.6
-
124
-
-
60849128839
-
Convection-enhanced delivery of nanocarriers for the treatment of brain tumors
-
Allard E, Passirani C, Benoit JP. Convection-enhanced delivery of nanocarriers for the treatment of brain tumors. Biomaterials. 2009; 30: 2302-2318.
-
(2009)
Biomaterials
, vol.30
, pp. 2302-2318
-
-
Allard, E.1
Passirani, C.2
Benoit, J.P.3
-
125
-
-
35948997685
-
Effects of drug efflux on convection-enhanced paclitaxel delivery to malignant gliomas: Technical note
-
discussion E882
-
Tanner PG, Holtmannspotter M, Tonn JC, Goldbrunner R. Effects of drug efflux on convection-enhanced paclitaxel delivery to malignant gliomas: technical note. Neurosurgery. 2007; 61: E880-882. discussion E882.
-
(2007)
Neurosurgery
, vol.61
-
-
Tanner, P.G.1
Holtmannspotter, M.2
Tonn, J.C.3
Goldbrunner, R.4
-
126
-
-
0041562430
-
Safety, tolerability, and tumor response of IL4-Pseudomonas exotoxin (NBI-3001) in patients with recurrent malignant glioma
-
Weber F, Asher A, Bucholz R, et al. Safety, tolerability, and tumor response of IL4-Pseudomonas exotoxin (NBI-3001) in patients with recurrent malignant glioma. J Neurooncol. 2003; 64: 125-137.
-
(2003)
J Neurooncol
, vol.64
, pp. 125-137
-
-
Weber, F.1
Asher, A.2
Bucholz, R.3
-
127
-
-
0344876636
-
Transferrin receptor ligand-targeted toxin conjugate (Tf-CRM107) for therapy of malignant gliomas
-
Weaver M, Laske DW. Transferrin receptor ligand-targeted toxin conjugate (Tf-CRM107) for therapy of malignant gliomas. J Neurooncol. 2003; 65: 3-13.
-
(2003)
J Neurooncol
, vol.65
, pp. 3-13
-
-
Weaver, M.1
Laske, D.W.2
-
128
-
-
0031451777
-
Tumor regression with regional distribution of the targeted toxin TF-CRM107 in patients with malignant brain tumors
-
Laske DW, Youle RJ, Oldfield EH. Tumor regression with regional distribution of the targeted toxin TF-CRM107 in patients with malignant brain tumors. Nature Medicine. 1997; 3: 1362-1368.
-
(1997)
Nature Medicine
, vol.3
, pp. 1362-1368
-
-
Laske, D.W.1
Youle, R.J.2
Oldfield, E.H.3
-
129
-
-
0032949676
-
Variables affecting convection-enhanced delivery to the striatum: A systematic examination of rate of infusion, cannula size, infusate concentration, and tissue-cannula sealing time
-
Chen MY, Lonser RR, Morrison PF, Governale LS, Oldfield EH. Variables affecting convection-enhanced delivery to the striatum: a systematic examination of rate of infusion, cannula size, infusate concentration, and tissue-cannula sealing time. J Neurosurg. 1999; 90: 315-320.
-
(1999)
J Neurosurg
, vol.90
, pp. 315-320
-
-
Chen, M.Y.1
Lonser, R.R.2
Morrison, P.F.3
Governale, L.S.4
Oldfield, E.H.5
-
130
-
-
67650378966
-
Targeted drug delivery for treatment and imaging of glioblastoma multiforme
-
Stukel JM, Caplan MR. Targeted drug delivery for treatment and imaging of glioblastoma multiforme. Expert Opin Drug Deliv. 2009; 6: 705-718.
-
(2009)
Expert Opin Drug Deliv
, vol.6
, pp. 705-718
-
-
Stukel, J.M.1
Caplan, M.R.2
-
131
-
-
78149479157
-
Phase III randomized trial of CED of IL13-PE38QQR vs Gliadel wafers for recurrent glioblastoma
-
Kunwar S, Chang S, Westphal M, et al. Phase III randomized trial of CED of IL13-PE38QQR vs Gliadel wafers for recurrent glioblastoma. Neuro Oncol. 2010; 12: 871-881.
-
(2010)
Neuro Oncol
, vol.12
, pp. 871-881
-
-
Kunwar, S.1
Chang, S.2
Westphal, M.3
-
132
-
-
77955608850
-
Poor drug distribution as a possible explanation for the results of the PRECISE trial
-
Sampson JH, Archer G, Pedain C, et al. Poor drug distribution as a possible explanation for the results of the PRECISE trial. J Neurosurg. 2010; 113: 301-309.
-
(2010)
J Neurosurg
, vol.113
, pp. 301-309
-
-
Sampson, J.H.1
Archer, G.2
Pedain, C.3
-
133
-
-
79951602633
-
Targeted therapy for high-grade glioma with the TGF-beta2 inhibitor trabedersen: Results of a randomized and controlled phase IIb study
-
Bogdahn U, Hau P, Stockhammer G, et al. Targeted therapy for high-grade glioma with the TGF-beta2 inhibitor trabedersen: results of a randomized and controlled phase IIb study. Neuro Oncol. 2011; 13: 132-142.
-
(2011)
Neuro Oncol
, vol.13
, pp. 132-142
-
-
Bogdahn, U.1
Hau, P.2
Stockhammer, G.3
-
134
-
-
84863563393
-
Convection-enhanced delivery catheter placements for high-grade gliomas: Complications and pitfalls
-
Shahar T, Ram Z, Kanner AA. Convection-enhanced delivery catheter placements for high-grade gliomas: complications and pitfalls. J Neurooncol. 2012; 107: 373-378.
-
(2012)
J Neurooncol
, vol.107
, pp. 373-378
-
-
Shahar, T.1
Ram, Z.2
Kanner, A.A.3
-
135
-
-
84869041386
-
Preparation, biodistribution and neurotoxicity of liposomal cisplatin following convection enhanced delivery in normal and F98 glioma bearing rats
-
Huo T, Barth RF, Yang W, et al. Preparation, biodistribution and neurotoxicity of liposomal cisplatin following convection enhanced delivery in normal and F98 glioma bearing rats. PloS one. 2012; 7: e48752.
-
(2012)
PloS One
, vol.7
-
-
Huo, T.1
Barth, R.F.2
Yang, W.3
-
136
-
-
77953621113
-
Convection-enhanced delivery of free gadolinium with the recombinant immunotoxin MR1-1
-
Ding D, Kanaly CW, Bigner DD, et al. Convection-enhanced delivery of free gadolinium with the recombinant immunotoxin MR1-1. J Neurooncol. 2010; 98: 1-7.
-
(2010)
J Neurooncol
, vol.98
, pp. 1-7
-
-
Ding, D.1
Kanaly, C.W.2
Bigner, D.D.3
-
137
-
-
84864098552
-
Safety and feasibility of convection-enhanced delivery of nimustine hydrochloride co-infused with free gadolinium for real-time monitoring in the primate brain
-
Sugiyama S, Saito R, Nakamura T, et al. Safety and feasibility of convection-enhanced delivery of nimustine hydrochloride co-infused with free gadolinium for real-time monitoring in the primate brain. Neurological Research. 2012; 34: 581-587.
-
(2012)
Neurological Research
, vol.34
, pp. 581-587
-
-
Sugiyama, S.1
Saito, R.2
Nakamura, T.3
-
138
-
-
77955622881
-
Cannula placement for effective convection-enhanced delivery in the nonhuman primate thalamus and brainstem: Implications for clinical delivery of therapeutics
-
Yin D, Richardson RM, Fiandaca MS, et al. Cannula placement for effective convection-enhanced delivery in the nonhuman primate thalamus and brainstem: implications for clinical delivery of therapeutics. J Neurosurg. 2010; 113: 240-248.
-
(2010)
J Neurosurg
, vol.113
, pp. 240-248
-
-
Yin, D.1
Richardson, R.M.2
Fiandaca, M.S.3
-
139
-
-
79953847153
-
Novel platform for MRI-guided convection-enhanced delivery of therapeutics: Preclinical validation in nonhuman primate brain
-
Richardson RM, Kells AP, Martin AJ, et al. Novel platform for MRI-guided convection-enhanced delivery of therapeutics: preclinical validation in nonhuman primate brain. Stereotactic and Functional Neurosurgery. 2011; 89: 141-151.
-
(2011)
Stereotactic and Functional Neurosurgery
, vol.89
, pp. 141-151
-
-
Richardson, R.M.1
Kells, A.P.2
Martin, A.J.3
-
140
-
-
79953247046
-
Imaging of convection enhanced delivery of toxins in humans
-
Mehta AI, Choi BD, Raghavan R, et al. Imaging of convection enhanced delivery of toxins in humans. Toxins. 2011; 3: 201-206.
-
(2011)
Toxins
, vol.3
, pp. 201-206
-
-
Mehta, A.I.1
Choi, B.D.2
Raghavan, R.3
-
141
-
-
84870879188
-
Ultrasound-assisted convection-enhanced delivery to the brain in vivo with a novel transducer cannula assembly
-
Lewis GK, Jr., Schulz ZR, Pannullo SC, Southard TL, Olbricht WL. Ultrasound-assisted convection-enhanced delivery to the brain in vivo with a novel transducer cannula assembly. J Neurosurg. 2012; 117: 1128-1140.
-
(2012)
J Neurosurg
, vol.117
, pp. 1128-1140
-
-
Lewis Jr., G.K.1
Schulz, Z.R.2
Pannullo, S.C.3
Southard, T.L.4
Olbricht, W.L.5
-
142
-
-
2542561964
-
Bevacizumab plus irinotecan, fluorouracil, and leucovorin for metastatic colorectal cancer
-
Hurwitz H, Fehrenbacher L, Novotny W, et al. Bevacizumab plus irinotecan, fluorouracil, and leucovorin for metastatic colorectal cancer. N Engl J Med. 2004; 350: 2335-2342.
-
(2004)
N Engl J Med
, vol.350
, pp. 2335-2342
-
-
Hurwitz, H.1
Fehrenbacher, L.2
Novotny, W.3
-
143
-
-
33845490014
-
Paclitaxel-carboplatin alone or with bevacizumab for non-small-cell lung cancer
-
Sandler A, Gray R, Perry MC, et al. Paclitaxel-carboplatin alone or with bevacizumab for non-small-cell lung cancer. N Engl J Med. 2006; 355: 2542-2550.
-
(2006)
N Engl J Med
, vol.355
, pp. 2542-2550
-
-
Sandler, A.1
Gray, R.2
Perry, M.C.3
-
144
-
-
78751620483
-
The paradoxical effect of bevacizumab in the therapy of malignant gliomas
-
Thompson EM, Frenkel EP, Neuwelt EA. The paradoxical effect of bevacizumab in the therapy of malignant gliomas. Neurology. 2011; 76: 87-93.
-
(2011)
Neurology
, vol.76
, pp. 87-93
-
-
Thompson, E.M.1
Frenkel, E.P.2
Neuwelt, E.A.3
-
145
-
-
79953330322
-
Antiangiogenesis enhances intratumoral drug retention
-
Ma J, Chen CS, Blute T,Waxman DJ. Antiangiogenesis enhances intratumoral drug retention. Cancer Res. 2011; 71: 2675-2685.
-
(2011)
Cancer Res
, vol.71
, pp. 2675-2685
-
-
Ma, J.1
Chen, C.S.2
Blute Twaxman, D.J.3
-
146
-
-
66749140894
-
Glioma angiogenesis: Towards novel RNA therapeutics
-
Wurdinger T, Tannous BA. Glioma angiogenesis: Towards novel RNA therapeutics. Cell Adhesion and Migration. 2009; 3: 230-235.
-
(2009)
Cell Adhesion and Migration
, vol.3
, pp. 230-235
-
-
Wurdinger, T.1
Tannous, B.A.2
-
147
-
-
38349145379
-
Modulation of the antitumor activity of metronomic cyclophosphamide by the angiogenesis inhibitor axitinib
-
Ma J,Waxman DJ. Modulation of the antitumor activity of metronomic cyclophosphamide by the angiogenesis inhibitor axitinib. Molecular Cancer Therapeutics. 2008; 7: 79-89.
-
(2008)
Molecular Cancer Therapeutics
, vol.7
, pp. 79-89
-
-
Ma Jwaxman, D.J.1
-
148
-
-
27944490875
-
VEGF as a therapeutic target in cancer
-
Ferrara N. VEGF as a therapeutic target in cancer. Oncology. 2005; 69 (Suppl 3): 11-16.
-
(2005)
Oncology
, vol.69
, Issue.SUPPL. 3
, pp. 11-16
-
-
Ferrara, N.1
-
149
-
-
65249185501
-
Bevacizumab and chemotherapy for recurrent glioblastoma: A single-institution experience
-
Nghiemphu PL, Liu W, Lee Y, et al. Bevacizumab and chemotherapy for recurrent glioblastoma: a single-institution experience. Neurology. 2009; 72: 1217-1222.
-
(2009)
Neurology
, vol.72
, pp. 1217-1222
-
-
Nghiemphu, P.L.1
Liu, W.2
Lee, Y.3
-
150
-
-
83955162975
-
Change in pattern of relapse after anti-angiogenic therapy in high-grade glioma
-
Narayana A, Kunnakkat SD, Medabalmi P, et al. Change in pattern of relapse after anti-angiogenic therapy in high-grade glioma. International Journal of Radiation Oncology, Biology, Physics. 2012; 82: 77-82.
-
(2012)
International Journal of Radiation Oncology, Biology, Physics
, vol.82
, pp. 77-82
-
-
Narayana, A.1
Kunnakkat, S.D.2
Medabalmi, P.3
-
151
-
-
77952309402
-
Tumor invasion after treatment of glioblastoma with bevacizumab: Radiographic and pathologic correlation in humans and mice
-
de Groot JF, Fuller G, Kumar AJ, et al. Tumor invasion after treatment of glioblastoma with bevacizumab: radiographic and pathologic correlation in humans and mice. Neuro Oncol. 2010; 12: 233-242.
-
(2010)
Neuro Oncol
, vol.12
, pp. 233-242
-
-
De Groot, J.F.1
Fuller, G.2
Kumar, A.J.3
|