Preparation, Biodistribution and Neurotoxicity of Liposomal Cisplatin following Convection Enhanced Delivery in Normal and F98 Glioma Bearing Rats

PLoS ONE

Volumn 7, Issue 11, 2012, Pages

  Huo, Tianyao ^a,e   Barth, Rolf F ^a   Yang, Weilian ^a   Nakkula, Robin J ^a   Koynova, Rumiana ^a   Tenchov, Boris ^a   Chaudhury, Abhik Ray ^a   Agius, Lawrence ^b   Boulikas, Teni ^c   Elleaume, Helene ^d   Lee, Robert J ^a  

^a OHIO STATE UNIVERSITY   (United States)

^b UNIVERSITY OF MALTA MEDICAL SCHOOL   (Malta)

^c Regulon Inc   (United States)

^d EUROPEAN SYNCHROTRON RADIATION FACILITY   (France)

^e UNIVERSITY OF FLORIDA COLLEGE OF MEDICINE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CISPLATIN; LIPID CHOLESTERYL HEMISUCCINATE; LIPOPLATIN; LIPOSOME; UNCLASSIFIED DRUG;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ANTINEOPLASTIC ACTIVITY; ARTICLE; CONTROLLED STUDY; CONVECTION ENHANCED DELIVERY; DEATH; DRUG CYTOTOXICITY; DRUG DELIVERY SYSTEM; DRUG DISTRIBUTION; DRUG FORMULATION; DRUG TOLERABILITY; GLIOMA; GLIOMA CELL; IN VITRO STUDY; IN VIVO STUDY; NEUROTOXICITY; NONHUMAN; PARTICLE SIZE; RAT; ZETA POTENTIAL;

ANIMALS; ANTINEOPLASTIC AGENTS; BRAIN NEOPLASMS; CELL LINE, TUMOR; CELL SURVIVAL; CISPLATIN; DOSE-RESPONSE RELATIONSHIP, DRUG; GLIOMA; LIPOSOMES; MALE; RATS; TRANSPLANTATION, HOMOLOGOUS;

RATTUS;

EID: 84869041386     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0048752     Document Type: Article

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