Prophage-induced changes in cellular cytochemistry and virulence

Bacteriophages in Health and Disease

Volumn , Issue , 2012, Pages 33-60

  Christie, Gail E ^a   Allison, Heather E ^b   Kuzio, John ^c   Michael, McShan W ^d   Waldor, Matthew K ^e   Kropinski, Andrew M ^f,g  

^a VIRGINIA COMMONWEALTH UNIVERSITY   (United States)

^b UNIVERSITY OF LIVERPOOL   (United Kingdom)

^c QUEEN S UNIVERSITY   (Canada)

^d UNIVERSITY OF OKLAHOMA   (United States)

^e BRIGHAM AND WOMEN S HOSPITAL   (United States)

^f UNIVERSITY OF GUELPH   (Canada)

^g PUBLIC HEALTH AGENCY OF CANADA   (Canada)

Author keywords

[No Author keywords available]

Indexed keywords

EID: 84878315155     PISSN: None     EISSN: None     Source Type: Book    
DOI: None     Document Type: Chapter

References (227)

1. Allison, G.E., Angeles, D., Tran-Dinh, N. and Verma, N.K. (2002) Complete genomic sequence of SfV, a serotype-converting temperate bacteriophage of Shigella flexneri. Journal of Bacteriology 184, 1974-1987.
2. Allison, G.E., Angeles, D.C., Huan, P. and Verma, N.K. (2003) Morphology of temperate bacteriophage SfV and characterisation of the DNA packaging and capsid genes: the structural genes evolved from two different phage families. Virology 308, 114-127.
3. Allison, H.E. (2007) Stx-phages: drivers and mediators of the evolution of STEC and STEClike pathogens. Future Microbiology 2, 165-174.
4. Asakura, M., Hinenoya, A., Alam, M.S., Shima, K., Zahid, S.H., Shi, L., Sugimoto, N., Ghosh, A.N., Ramamurthy, T., Faruque, S.M., Nair, G.B. and Yamasaki, S. (2007) An inducible lambdoid prophage encoding cytolethal distending toxin (Cdt-I) and a type III effector protein in enteropathogenic Escherichia coli. Proceedings of the National Academy of Sciences USA 104, 14483-14488.
5. Aziz, R.K., Edwards, R.A., Taylor, W.W., Low, D.E., McGeer, A. and Kotb, M. (2005) Mosaic prophages with horizontally acquired genes account for the emergence and diversification of the globally disseminated M1T1 clone of Streptococcus pyogenes. Journal of Bacteriology 187, 3311-3318.
6. Baba, T., Takeuchi, F., Kuroda, M., Yuzawa, H., Aoki, K., Oguchi, A., Nagai, Y., Iwama, N., Asano, K., Naimi, T., Kuroda, H., Cui, L., Yamamoto, K. and Hiramatsu, K. (2002) Genome and virulence determinants of high virulence communityacquired MRSA. Lancet 359, 1819-1827.
7. Bae, T., Baba, T., Hiramatsu, K. and Schneewind, O. (2006) Prophages of Staphylococcus aureus Newman and their contribution to virulence. Molecular Microbiology 62, 1035-1047.
8. Bania, J., Dabrowska, A., Bystron, J., Korzekwa, K., Chrzanowska, J. and Molenda, J. (2006) Distribution of newly described enterotoxin-like genes in Staphylococcus aureus from food. International Journal of Food Microbiology 108, 36-41.
9. Barondess, J.J. and Beckwith, J. (1990) A bacterial virulence determinant encoded by lysogenic coliphage λ. Nature 346 (6287), 871-874.
10. Bender, R.A. (1981) Improved generalized transducing bacteriophage for Caulobacter crescentus. Journal of Bacteriology 148, 734-735.
11. Bendig, M.M. and Drexler, H. (1977) Transduction of bacteriophage Mu by bacteriophage T1. Journal of Virology 22, 640-645.
12. Bensing, B.A., Siboo, I.R. and Sullam, P.M. (2001) Proteins PblA and PblB of Streptococcus mitis, which promote binding to human platelets, are encoded within a lysogenic bacteriophage. Infection and Immunity 69, 6186-6192.
13. Beres, S.B., Sylva, G.L., Barbian, K.D., Lei, B., Hoff, J.S., Mammarella, N.D., Liu, M.Y., Smoot, J.C., Porcella, S.F., Parkins, L.D., Campbell, D.S., Smith, T.M., McCormick, J.K., Leung, D.Y., Schlievert, P.M. and Musser, J.M. (2002) Genome sequence of a serotype M3 strain of group A Streptococcus: phage-encoded toxins, the high-virulence phenotype, and clone emergence. Proceedings of the National Academy of Sciences USA 99, 10078-10083.
14. Bergan, T. and Midtvedt, T. (1975) Epidemiological markers for Pseudomonas aeruginosa. Acta Pathologica Microbiologica Scandanavica, 83B, 1-9.
15. Betley, M.J. and Mekalanos, J.J. (1985) Staphylococcal enterotoxin A is encoded by phage. Science 229, 185-187.
16. Bokarewa, M.I., Jin, T. and Tarkowski, A. (2006) Staphylococcus aureus: staphylokinase. International Journal of Biochemistry and Cell Biology 38, 504-509.
17. Bossi, L. and Figueroa-Bossi, N. (2005) Prophage arsenal of Salmonella enterica serovar Typhimurium, In: Waldor, M.K., Friedman, D.I. and Adhya, S.L. (eds) Phages: Their Role in Bacterial Pathogenesis and Biotechnology. ASM Press, Washington, DC, pp. 165-186.
18. Boyd, J.S. (1950) The symbiotic bacteriophages of Salmonella typhimurium. Journal of Pathology and Bacteriology 62, 501-517.
19. Braconier, J.H. and Rollof, J. (1991) Influence by staphylococcal lipase on granulocyte metabolism and killing of bacteria. Zentralblatt für Bakteriologie 276, 68-72.
20. Brinkmann, V., Reichard, U., Goosmann, C., Fauler, B., Uhlemann, Y., Weiss, D.S., Weinrauch, Y. and Zychlinsky, A. (2004) Neutrophil extracellular traps kill bacteria. Science 303, 1532-1535.
21. Brüssow, H., Canchaya, C. and Hardt, W.D.(2004) Phages and the evolution of bacterial pathogens: from genomic rearrangements to lysogenic conversion. Microbiology and Molecular Biology Reviews 68, 560-602.
22. Buchanan, J.T., Simpson, A.J., Aziz, R.K., Liu, G.Y., Kristian, S.A., Kotb, M., Feramisco, J. and Nizet, V. (2006) DNase expression allows the pathogen group A Streptococcus to escape killing in neutrophil extracellular traps. Current Biology 16, 396-400.
23. Buck, G., Groman, N. and Falkow, S. (1978) Relationship between β converting and λ nonconverting corynebacteriophage DNA. Nature 271, 683-685.
24. Buck, G.A., Cross, R.E., Wong, T.P., Loera, J. and Groman, N. (1985) DNA relationships among some tox-bearing corynebacteriophages. Infection and Immunity 49, 679-684.
25. Busch, A.W., Reijerse, E.J., Lubitz, W., Hofmann, E. and Frankenberg-Dinkel, N. (2011) Radical mechanism of cyanophage phycoerythrobilin synthase (PebS). Biochemical Journal 433, 469-476.
26. Canosi, U., Luder, G. and Trautner, T.A. (1982) SPP1-mediated plasmid transduction. Journal of Virology 44, 431-436.
27. Carroll, J.D., Cafferkey, M.T. and Coleman, D.C. (1993) Serotype F double-and triple-converting phage insertionally inactivate the Staphylococcus aureus β-toxin determinant by a common molecular mechanism. FEMS Microbiology Letters 106, 147-155.
28. Carroll, P.J. and Francis, P.G. (1985) The basic phage set for typing bovine staphylococci. Journal of Hygiene 95, 665-669.
29. Castillo, F.J. and Bartell, P.F. (1974) Studies on the bacteriophage 2 receptor of Pseudomonas aeruginosa. Journal of Virology 14, 902-909.
30. Cerquetti, M.C., Hooke, A.M., Cerquetti, M.C. and Hooke, A.M. (1993) Vi I typing phage for generalized transduction of Salmonella typhi. Journal of Bacteriology 175, 5294-5296.
31. Choorit, W., Kaneko, J., Muramoto, K. and Kamio, Y. (1995) Existence of a new protein component with the same function as the LukF component of leukocidin or λ-hemolysin and its gene in Staphylococcus aureus P83. FEBS Letters 357, 260-264.
32. Chopin, M.C., Chopin, A. and Bidnenko, E. (2005) Phage abortive infection in lactococci: variations on a theme. Current Opinion in Microbiology 8, 473-479.
33. Chua, K., Seemann, T., Harrison, P.F., Davies, J.K., Coutts, S.J., Chen, H., Haring, V., Moore, R., Howden, B.P. and Stinear, T.P. (2010) Complete genome sequence of Staphylococcus aureus strain JKD6159, a unique Australian clone of ST93-IV community methicillin-resistant Staphylococcus aureus. Journal of Bacteriology 192, 5556-5557.
34. Cleary, P.P., Kaplan, E.L., Handley, J.P., Wlazlo, A., Kim, M.H., Hauser, A.R. and Schlievert, P.M. (1992) Clonal basis for resurgence of serious Streptococcus pyogenes disease in the 1980s. Lancet 339, 518-521.
35. Clerget, M. and Boccard, F. (1996) Phage HK022 Roi protein inhibits phage lytic growth in Escherichia coli integration host factor mutants. Journal of Bacteriology 178, 4077-4083.
36. Coleman, D.C., Arbuthnott, J.P., Pomeroy, H.M. and Birkbeck, T.H. (1986) Cloning and expression in Escherichia coli and Staphylococcus aureus of the β-lysin determinant from Staphylococcus aureus: evidence that bacteriophage conversion of β-lysin activity is caused by insertional inactivation of the β-lysin determinant. Microbial Pathogenesis 1, 549-564.
37. Coleman, D.C., Sullivan, D.J., Russell, R.J., Arbuthnott, J.P., Carey, B.F. and Pomeroy, H.M. (1989) Staphylococcus aureus bacteriophages mediating the simultaneous lysogenic conversion of β-lysin, staphylokinase and enterotoxin A: molecular mechanism of triple conversion. Journal of General Microbiology 135, 1679-1697.
38. Cólon, A.E., Cole, R.M. and Leonard, C.G. (1972) Intergroup lysis and transduction by streptococcal bacteriophages. Journal of Virology 9, 551-553.
39. Davis, B.M. and Waldor, M.K. (2000) CTXφ contains a hybrid genome derived from tandemly integrated elements. Proceedings of the National Academy of Sciences USA 97, 8572-8577.
40. Davis, B.M. and Waldor, M.K. (2003) Filamentous phages linked to virulence of Vibrio cholerae. Current Opinion in Microbiology 6, 35-42.
41. Davis, B.M., Lawson, E.H., Sandkvist, M., Ali, A., Sozhamannan, S. and Waldor, M.K. (2000a) Convergence of the secretory pathways for cholera toxin and the filamentous phage, CTXφ. Science 288, 333-335.
42. Davis, B.M., Moyer, K.E., Boyd, E.F. and Waldor, M.K. (2000b) CTX prophages in classical biotype Vibrio cholerae: functional phage genes but dysfunctional phage genomes. Journal of Bacteriology 182, 6992-6998.
43. Davis, B.M., Kimsey, H.H., Kane, A.V. and Waldor, M.K. (2002) A satellite phage-encoded antirepressor induces repressor aggregation and cholera toxin gene transfer. EMBO Journal 21, 4240-4249.
44. Daz, R., de Torrontegui, G. and Canovas, J.L. (1976) [Generalized transduction of Pseudomonas putida with a thermosensitive mutant of phage pf16h2]. Microbiologia Espanola 29, 33-45 (in Spanish).
45. de Haas, C.J., Veldkamp, K.E., Peschel, A., Weerkamp, F., van Wamel, W.J., Heezius, E.C., Poppelier, M.J., Van Kessel, K.P. and Vvan Strijp, J.A. (2004) Chemotaxis inhibitory protein of Staphylococcus aureus, a bacterial antiinflammatory agent. Journal of Experimental Medicine 199, 687-695.
46. de Lencastre, H. and Archer, L.J. (1980) Characterization of bacteriophage SPP1 transducing particles. Journal of General Microbiology 117, 347-355.
47. Dempsey, R.M., Carroll, D., Kong, H., Higgins, L., Keane, C.T. and Coleman, D.C. (2005) Sau42I, a BcgI-like restriction-modification system encoded by the Staphylococcus aureus quadruple-converting phage φ42. Microbiology 151, 1301-1311.
48. Dereeper, A., Guignon, V., Blanc, G., Audic, S., Buffet, S., Chevenet, F., Dufayard, J.F., Guindon, S., Lefort, V., Lescot, M., Claverie, J.M. and Gascuel, O. (2008) Phylogeny.fr: robust phylogenetic analysis for the non-specialist. Nucleic Acids Research 36 (Web Server issue), W465-W469.
49. Diep, B.A. and Otto, M. (2008) The role of virulence determinants in community-associated MRSA pathogenesis. Trends in Microbiology 16, 361-369.
50. Diep, B.A., Gill, S.R., Chang, R.F., Phan, T.H., Chen, J.H., Davidson, M.G., Lin, F., Lin, J., Carleton, H.A., Mongodin, E.F., Sensabaugh, G.F. and Perdreau-Remington, F. (2006) Complete genome sequence of USA300, an epidemic clone of community-acquired meticillin-resistant Staphylococcus aureus. Lancet 367, 731-739.
51. Diep, B.A., Palazzolo-Ballance, A.M., Tattevin, P., Basuino, L., Braughton, K.R., Whitney, A.R., Chen, L., Kreiswirth, B.N., Otto, M., DeLeo, F.R. and Chambers, H.F. (2008) Contribution of Panton-Valentine leukocidin in communityassociated methicillin-resistant Staphylococcus aureus pathogenesis. PLoS ONE 3, e3198.
52. Dimitracopoulos, G. and Bartell, P.F. (1979) Phagerelated surface modification of Pseudomonas aeruginosa: effects on the biological activity of viable cells. Infection and Immunity 23, 87-93.
53. Dinges, M.M., Orwin, P.M. and Schlievert, P.M. (2000) Exotoxins of Staphylococcus aureus. Clinical Microbiology Reviews 13, 16-34.
54. Drexler, H. (1970) Transduction by bacteriophage T1. Proceedings of the National Academy of Sciences USA 66, 1083-1088.
55. Drexler, H. (1977) Specialized transduction of the biotin region of Escherichia coli by phage T1. Molecular and General Genetics 152, 59-63.
56. Dzhusupova, A.B., Plotnikova, T.G., Krylov, V.N., Dzhusupova, A.B., Plotnikova, T.G. and Krylov, V.N. (1982) Detection of transduction by virulent bacteriophage φ KZ of Pseudomonas aeruginosa chromosomal markers in the presence of plasmid RMS148. Genetika 18, 1799-1802.
57. Eklund, M.W. and Poysky, F.T. (1974) Interconversion of type C and D strains of Clostridium botulinum by specific bacterio phages. Applied Microbiology 27, 251-258.
58. Eklund, M.W., Poysky, F.T., Reed, S.M. and Smith, C.A. (1971) Bacteriophage and the toxigenicity of Clostridium botulinum type C. Science 172, 480-482.
59. Eklund, M.W., Poysky, F.T. and Reed, S.M. (1972) Bacteriophage and the toxigenicity of Clostridium botulinum type D. Nature New Biology 235, 16-17.
60. Eklund, M.W., Poysky, F.T., Meyers, J.A. and Pelroy, G.A. (1974) Interspecies conversion of Clostridium botulinum type C to Clostridium novyi type A by bacteriophage. Science 186, 456-458.
61. Eklund, M.W., Poysky, F.T., Peterson, M.E. and Meyers, J.A. (1976) Relationship of bacteriophages to alpha toxin production in Clostridium novyi types A and B. Infection and Immunity 14, 793-803.
62. Feng, P., Lampel, K.A., Karch, H. and Whittam, T.S. (1998) Genotypic and phenotypic changes in the emergence of Escherichia coli O157:H7. Journal of Infectious Diseases 177, 1750-1753.
63. Ferretti, J.J., McShan, W.M., Ajdic, D., Savic, D.J., Savic, G., Lyon, K., Primeaux, C., Sezate, S., Suvorov, A.N., Kenton, S., Lai, H.S., Lin, S.P., Qian, Y., Jia, H.G., Najar, F.Z., Ren, Q., Zhu, H., Song, L., White, J., Yuan, X., Clifton, S.W., Roe, B.A. and McLaughlin, R. (2001) Complete genome sequence of an M1 strain of Streptococcus pyogenes. Proceedings of the National Academy of Sciences USA 98, 4658-4663.
64. Figueroa-Bossi, N., Uzzau, S., Maloriol, D. and Bossi, L. (2001) Variable assortment of prophages provides a transferable repertoire of pathogenic determinants in Salmonella. Molecular Microbiology 39, 260-271.
65. Finck-Barbancon, V., Duportail, G., Meunier, O. and Colin, D.A. (1993) Pore formation by a twocomponent leukocidin from Staphylococcus aureus within the membrane of human polymorphonuclear leukocytes. Biochimica et Biophysica Acta 1182, 275-282.
66. Fogg, P.C., Rigden, D.J., Saunders, J.R., McCarthy, A.J. and Allison, H.E. (2011) Characterization of the relationship between integrase, excisionase and antirepressor activities associated with a superinfecting Shiga toxin encoding bacteriophage. Nucleic Acids Research 39, 2116-2129.
67. Fraser, J.D. and Proft, T. (2008) The bacterial superantigen and superantigen-like proteins. Immunology Reviews, 225, 226-243.
68. Freeman, V.J. (1951) Studies on the virulence of bacteriophage-infected strains of Corynebacterium diphtheriae. Journal of Bacteriology 61, 675-688.
69. Freeman, V.J. and Morse, I.U. (1952) Further observations on the change to virulence of bacteriophage-infected avirulent strains of Corynebacterium diphtheriae. Journal of Bacteriology 63, 407-414.
70. Frobisher, M. and Brown, J.H. (1927) Transmissible toxicogenicity of Streptococci. Bulletin of the Johns Hopkins Hospital, 41, 107-173.
71. Fromageau, A., Gilbert, F.B., Prévost, G. and Rainard, P. (2010) Binding of the Staphylococcus aureus leucotoxin LukM to its leucocyte targets. Microbial Pathogenesis 49, 354-362.
72. Gill, S.R., Fouts, D.E., Archer, G.L., Mongodin, E.F., DeBoy, R.T., Ravel, J., Paulsen, I.T., Kolonay, J.F., Brinkac, L., Beanan, M., Dodson, R.J., Daugherty, S.C., Madupu, R., Angiuoli, S.V., Durkin, A.S., Haft, D.H., Vamathevan, J., Khouri, H., Utterback, T., Lee, C., Dimitrov, G., Jiang, L., Qin, H., Weidman, J., Tran, K., Kang, K., Hance, I.R., Nelson, K.E. and Fraser, C.M. (2005) Insights on evolution of virulence and resistance from the complete genome analysis of an early methicillin-resistant Staphylococcus aureus strain and a biofilm-producing methicillinresistant Staphylococcus epidermidis strain. Journal of Bacteriology 187, 2426-2438.
73. Gillet, Y., Issartel, B., Vanhems, P., Fournet, J.C., Lina, G., Bes, M., Vandenesch, F., Piemont, Y., Brousse, N., Floret, D. and Etienne, J. (2002) Association between Staphylococcus aureus strains carrying gene for Panton-Valentine leukocidin and highly lethal necrotising pneumonia in young immunocompetent patients. Lancet 359, 753-759.
74. Goerke, C. and Wolz, C. (2010) Adaptation of Staphylococcus aureus to the cystic fibrosis lung. International Journal of Medical Microbiology 300, 520-525.
75. Goerke, C., Wirtz, C., Fluckiger, U. and Wolz, C. (2006) Extensive phage dynamics in Staphylococcus aureus contributes to adaptation to the human host during infection. Molecular Microbiology 61, 1673-1685.
76. Goerke, C., Pantucek, R., Holtfreter, S., Schulte, B., Zink, M., Grumann, D., Broker, B.M., Doskar, J. and Wolz, C. (2009) Diversity of prophages in dominant Staphylococcus aureus clonal lineages. Journal of Bacteriology 191, 3462-3468.
77. Gorbunova, S.A., Akhverdian, V.S., Cheremukhina, L.V. and Krylov, V.N. (1985) Effective method of transduction with virulent phage pf16 using specific mutants of Pseudomonas putida PpG1. Genetika 21, 872-874.
78. Grimont, P.A.D., Weill, F.-X. and WHO Collaborating Center for Reference and Research on Salmonella (2007) Antigenic formulae of the Salmonella serovars, 9th edn. Institut Pasteur, Paris, France.
79. Groman, N.B. (1955) Evidence for the active role of bacteriophage in the conversion of nontoxigenic Corynebacterium diphtheriae to toxin production. Journal of Bacteriology 69, 9-15.
80. Groman, N.B. (1984) Conversion by corynephages and its role in the natural history of diphtheria. Journal of Hygiene 93, 405-417.
81. Guinane, C.M., Ben Zakour, N.L., Tormo-Mas, M.A., Weinert, L.A., Lowder, B.V., Cartwright, R.A., Smyth, D.S., Smyth, C.J., Lindsay, J.A., Gould, K.A., Witney, A., Hinds, J., Bollback, J.P., Rambaut, A., Penades, J.R. and Fitzgerald, J.R. (2010) Evolutionary genomics of Staphylococcus aureus reveals insights into the origin and molecular basis of ruminant host adaptation. Genome Biology and Evolution 2, 454-466.
82. Hauser, D., Gibert, M., Eklund, M.W., Boquet, P. and Popoff, M.R. (1993) Comparative analysis of C3 and botulinal neurotoxin genes and their environment in Clostridium botulinum types C and D. Journal of Bacteriology 175, 7260-7268.
83. Highlander, S.K., Hulten, K.G., Qin, X., Jiang, H., Yerrapragada, S., Mason, E.O. Jr, Shang, Y., Williams, T.M., Fortunov, R.M., Liu, Y., Igboeli, O., Petrosino, J., Tirumalai, M., Uzman, A., Fox, G.E., Cardenas, A.M., Muzny, D.M., Hemphill, L., Ding, Y., Dugan, S., Blyth, P.R., Buhay, C.J., Dinh, H.H., Hawes, A.C., Holder, M., Kovar, C.L., Lee, S.L., Liu, W., Nazareth, L.V., Wang, Q., Zhou, J., Kaplan, S.L. and Weinstock, G.M. (2007) Subtle genetic changes enhance virulence of methicillin resistant and sensitive Staphylococcus aureus. BMC Microbiology 7, 99.
84. Holden, M.T.G., Feil, E.J., Lindsay, J.A., Peacock, S.J., Day, N.P.J., Enright, M.C., Foster, T.J., Moore, C.E., Hurst, L., Atkin, R., Barron, A., Bason, N., Bentley, S.D., Chillingworth, C., Chillingworth, T., Churcher, C., Clark, L., Corton, C., Cronin, A., Doggett, J., Dowd, L., Feltwell, T., Hance, Z., Harris, B., Hauser, H., Holroyd, S., Jagels, K., James, K.D., Lennard, N., Line, A., Mayes, R., Moule, S., Mungall, K., Ormond, D., Quail, M.A., Rabbinowitsch, E., Rutherford, K., Sanders, M., Sharp, S., Simmonds, M., Stevens, K., Whitehead, S., Barrell, B.G., Spratt, B.G. and Parkhill, J. (2004) Complete genomes of two clinical Staphylococcus aureus strains: evidence for the rapid evolution of virulence and drug resistance. Proceedings of the National Academy of Sciences USA 101, 9786-9791.
85. Holden, M.T., Lindsay, J.A., Corton, C., Quail, M.A., Cockfield, J.D., Pathak, S., Batra, R., Parkhill, J., Bentley, S.D. and Edgeworth, J.D. (2010) Genome sequence of a recently emerged, highly transmissible, multi-antibiotic-and antiseptic-resistant variant of methicillinresistant Staphylococcus aureus, sequence type 239 (TW). Journal of Bacteriology 192, 888-892.
86. Holloway, B.W. and Cooper, G.N. (1962) Lysogenic conversion in Pseudomonas aeruginosa. Journal of Bacteriology 84, 1324.
87. Holloway, B.W., Krishnapillai, V. and Stanisich, V. (1971) Pseudomonas genetics. Annual Review of Genetics 425-466.
88. Holmes, A., Ganner, M., McGuane, S., Pitt, T.L., Cookson, B.D. and Kearns, A.M. (2005) Staphylococcus aureus isolates carrying Panton-Valentine leucocidin genes in England and Wales: frequency, characterization, and association with clinical disease. Journal of Clinical Microbiology 43, 2384-2390.
89. Holmes, R.K. and Barksdale, L. (1970) Comparative studies with tox+ and tox-corynebacteriophages. Journal of Virology 5, 783-784.
90. Holochova, P., Ruzickova, V., Dostalova, L., Pantucek, R., Petras, P. and Doskar, J. (2010) Rapid detection and differentiation of the exfoliative toxin A-producing Staphylococcus aureus strains based on φETA prophage polymorphisms. Diagnostic Microbiology and Infectious Disease 66, 248-252.
91. Hyder, S.L. and Streitfeld, M.M. (1978) Transfer of erythromycin resistance from clinically isolated lysogenic strains of Streptococcus pyogenes via their endogenous phage. Journal of Infectious Diseases 138, 281-286.
92. Hyman, P. and Abedon, S.T. (2010) Bacteriophage host range and bacterial resistance. Advances in Applied Microbiology, 70, 217-248.
93. Iandolo, J.J., Worrell, V., Groicher, K.H., Qian, Y., Tian, R., Kenton, S., Dorman, A., Ji, H., Lin, S., Loh, P., Qi, S., Zhu, H. and Roe, B.A. (2002) Comparative analysis of the genomes of the temperate bacteriophages φ11, φ12 and φ13 of Staphylococcus aureus 8325. Gene 289, 109-118.
94. Inoue, K. and Iida, H. (1968) Bacteriophages of Clostridium botulinum. Journal of Virology 2, 537-540.
95. Inoue, K. and Iida, H. (1970) Conversion of toxigenicity in Clostridium botulinum type C. Japanese Journal of Microbiology 14, 87-89.
96. Inoue, K. and Iida, H. (1971) Phage conversion of toxigenicity in Clostridium botulinum types C and D. Japanese Journal of Microbiology 24, 53-56.
97. Izdebska-Szymona, K., Tyski, S., Drela, N., Sobiczewska, E., Laskowska, M., Kalkhof, D. and Hryniewicz, W. (1992) Staphylococcal lipase affects phagocytosis of Staphylococcus aureus by human granulocytes and monocytes. Acta Microbiologica Polonica 41, 49-56.
98. Jin, T., Bokarewa, M., Foster, T., Mitchell, J., Higgins, J. and Tarkowski, A. (2004) Staphy lococcus aureus resists human defensins by production of staphylokinase, a novel bacterial evasion mechanism. Journal of Immunology 172, 1169-1176.
99. Johnson, W.M. and Lior, H. (1987) Response of Chinese hamster ovary cells to a cytolethal distending toxin (CDT) of Escherichia coli and possible misinterpretation as heat-labile (LT) enterotoxin. FEMS Microbiology Letters 43, 19-23.
100. Juhala, R.J., Ford, M.E., Duda, R.L., Youlton, A., Hatfull, G.F. and Hendrix, R.W. (2000) Genetic sequences of bacteriophages HK97 and HK022: pervasive genetic mosaicism in the lambdoid bacteriophages. Journal of Molecular Biology 299, 27-51.
101. Just, I., Mohr, C., Schallehn, G., Menard, L., Didsbury, J.R., Vandekerckhove, J., van Damme, J. and Aktories, K. (1992) Purification and characterization of an ADP-ribosyltransferase produced by Clostridium limosum. Journal of Biological Chemistry 267, 10274-10280.
102. Kahankova, J., Pantucek, R., Goerke, C., Ruzickova, V., Holochova, P. and Doskar, J. (2010) Multilocus PCR typing strategy for differentiation of Staphylococcus aureus siphoviruses reflecting their modular genome structure. Environmental Microbiology 12, 2527-2538.
103. Kaneko, J., Kimura, T., Narita, S., Tomita, T. and Kamio, Y. (1998) Complete nucleotide sequence and molecular characterization of the temperate staphylococcal bacteriophage φPVL carrying Panton-Valentine leukocidin genes. Gene 215, 57-67.
104. Kaper, J.B., Nataro, J.P. and Mobley, H.L. (2004) Pathogenic Escherichia coli. Nature Reviews Microbiology 2, 123-140.
105. Karmali, M.A., Petric, M., Lim, C., Fleming, P.C. and Steele, B.T. (1983) Escherichia coli cytotoxin, haemolytic-uraemic syndrome, and haemorrhagic colitis. Lancet 2, 1299-1300.
106. Kobayashi, S.D. and DeLeo, F.R. (2009) An update on community-associated MRSA virulence. Current Opinion in Pharmacology 9, 545-551.
107. Kondo, I. and Fujise, K. (1977) Serotype B staphylococcal bacteriophage singly converting staphylokinase. Infection and Immunity 18, 266-272.
108. König, B., Prévost, G., Piémont, Y. and König, W. (1995) Effects of Staphylococcus aureus leukocidins on inflammatory mediator release from human granulocytes. Journal of Infectious Diseases 171, 607-613.
109. Kropinski, A.M. (2000) Sequence of the genome of the temperate, serotype-converting, Pseudomonas aeruginosa bacteriophage D3. Journal of Bacteriology 182, 6066-6074.
110. Kumagai, R., Nakatani, K., Ikeya, N., Kito, Y., Kaidoh, T. and Takeuchi, S. (2007) Quadruple or quintuple conversion of hlb, sak, sea (or sep), scn, and chp genes by bacteriophages in non-β-hemolysin-producing bovine isolates of Staphylococcus aureus. Veterinary Microbiology 122, 190-195.
111. Kuroda, M., Ohta, T., Uchiyama, I., Baba, T., Yuzawa, H., Kobayashi, I., Cui, L., Oguchi, A., Aoki, K., Nagai, Y., Lian, J., Ito, T., Kanamori, M., Matsumaru, H., Maruyama, A., Murakami, H., Hosoyama, A., Mizutani-Ui, Y., Takahashi, N.K., Sawano, T., Inoue, R., Kaito, C., Sekimizu, K., Hirakawa, H., Kuhara, S., Goto, S., Yabuzaki, J., Kanehisa, M., Yamashita, A., Oshima, K., Furuya, K., Yoshino, C., Shiba, T., Hattori, M., Ogasawara, N., Hayashi, H. and Hiramatsu, K. (2001) Whole genome sequencing of meticillinresistant Staphylococcus aureus. Lancet 357, 1225-1240.
112. Kuzio, J. and Kropinski, A.M. (1983) O-antigen conversion in Pseudomonas aeruginosa PAO1 by bacteriophage D3. Journal of Bacteriology 155, 203-212.
113. Kwan, T., Liu, J., DuBow, M., Gros, P. and Pelletier, J. (2005) The complete genomes and proteomes of 27 Staphylococcus aureus bacteriophages. Proceedings of the National Academy of Sciences USA 102, 5174-5179.
114. Labrie, S.J., Samson, J.E. and Moineau, S. (2010) Bacteriophage resistance mechanisms. Nature Reviews Microbiology 8, 317-327.
115. Ladhani, S., Joannou, C.L., Lochrie, D.P., Evans, R.W. and Poston, S.M. (1999) Clinical, microbial, and biochemical aspects of the exfoliative toxins causing staphylococcal scalded-skin syndrome. Clinical Microbiology Reviews 12, 224-242.
116. Lahteenmaki, K., Edelman, S. and Korhonen, T.K. (2005) Bacterial metastasis: the host plasminogen system in bacterial invasion. Trends in Microbiology 13, 79-85.
117. Lainhart, W., Stolfa, G. and Koudelka, G.B. (2009) Shiga toxin as a bacterial defense against a eukaryotic predator, Tetrahymena thermophila. Journal of Bacteriology 191, 5116-5122.
118. Lanyi, B. and Lantos, J. (1976) Antigenic changes in Pseudomonas aeruginosa in vivo and after lysogenization in vitro. Acta Microbiology Academy of Science Hungary 23, 337-351.
119. Lee, C.Y. and Iandolo, J.J. (1986) Lysogenic conversion of staphylococcal lipase is caused by insertion of the bacteriophage L54a genome into the lipase structural gene. Journal of Bacteriology 166, 385-391.
120. Lee, J.H., Choi, S.Y., Jeon, Y.S., Lee, H.R., Kim, E.J., Nguyen, B.M., Hien, N.T., Ansaruzzaman, M., Islam, M.S., Bhuiyan, N.A., Niyogi, S.K., Sarkar, B.L., Nair, G.B., Kim, D.S., Lopez, A.L., Czerkinsky, C., Clemens, J.D., Chun, J. and Kim, D.W. (2009) Classification of hybrid and altered Vibrio cholerae strains by CTX prophage and RS1 element structure. Journal of Microbiology 47, 783-788.
121. Lemire, S., Figueroa-Bossi, N. and Bossi, L. (2008) Prophage contribution to Salmonella virulence and diversity. In: Hensel, M. (ed.) Horizontal Gene Transfer in the Evolution of Pathogenesis. Cambridge University Press, Cambridge, UK, pp. 159-192.
122. Leonard, C.G., Colon, A.E. and Cole, R.M. (1968) Transduction in group A Streptococcus. Biochemical and Biophysical Research Communications 30, 130-135.
123. Lina, G., Piemont, Y., Godail-Gamot, F., Bes, M., Peter, M.O., Gauduchon, V., Vandenesch, F. and Etienne, J. (1999) Involvement of Panton-Valentine leukocidin-producing Staphylococcus aureus in primary skin infections and pneumonia. Clinical Infectious Diseases 29, 1128-1132.
124. Lindsay, J.A. (2010) Genomic variation and evolution of Staphylococcus aureus. International Journal of Medical Microbiology 300, 98-103.
125. Lindsay, J.A. and Holden, M.T. (2004) Staphylococcus aureus: superbug, super genome? Trends in Microbiology 12, 378-385.
126. Liu, J., Dehbi, M., Moeck, G., Arhin, F., Bauda, P., Bergeron, D., Callejo, M., Ferretti, V., Ha, N., Kwan, T., McCarty, J., Srikumar, R., Williams, D., Wu, J.J., Gros, P., Pelletier, J. and DuBow, M. (2004) Antimicrobial drug discovery through bacteriophage genomics. Nature Biotechnology 22, 185-191.
127. Liu, P.V. (1969) Changes in somatic antigens of Pseudomonas aeruginosa induced by bacteriophages. Journal of Infectious Diseases 119, 237-246.
128. Los, M., Kuzio, J., McConnell, M., Kropinski, A.M., Wegrzyn, G. and Christie, G.E. (2010) Lysogenic conversion in bacteria of importance to the food industry. In: Sabour, P. and Griffiths, M. (eds) Bacteriophages in the Detection and Control of Foodborne Pathogens. ASM Press, Washington, DC, pp. 157-198.
129. Lowder, B.V., Guinane, C.M., Ben Zakour, N.L., Weinert, L.A., Conway-Morris, A., Cartwright, R.A., Simpson, A.J., Rambaut, A., Nubel, U. and Fitzgerald, J.R. (2009) Recent human-topoultry host jump, adaptation, and pandemic spread of Staphylococcus aureus. Proceedings of the National Academy of Sciences USA 106, 19545-19550.
130. Ma, X.X., Ito, T., Chongtrakool, P. and Hiramatsu, K. (2006) Predominance of clones carrying Panton-Valentine leukocidin genes among methicillin-resistant Staphylococcus aureus strains isolated in Japanese hospitals from 1979 to 1985. Journal of Clinical Microbiology 44, 4515-4527.
131. Ma, X.X., Ito, T., Kondo, Y., Cho, M., Yoshizawa, Y., Kaneko, J., Katai, A., Higashiide, M., Li, S. and Hiramatsu, K. (2008) Two different Panton-Valentine leukocidin phage lineages predominate in Japan. Journal of Clinical Microbiology 46, 3246-3258.
132. Mathews, A.M. and Novick, R.P. (2005) Staphylococcal phages. In: Waldor, M.K., Friedman, D.I. and Adhya, S.L. (eds) Phages: Their Role in Bacterial Pathogenesis and Biotechnology. ASM Press, Washington, DC, pp. 297-318.
133. McCormick, J.K., Yarwood, J.M. and Schlievert, P.M. (2001) Toxic shock syndrome and bacterial superantigens: an update. Annual Review of Microbiology 55, 77-104.
134. McLeod, S.M., Kimsey, H.H., Davis, B.M. and Waldor, M.K. (2005) CTXφ and Vibrio cholerae: exploring a newly recognized type of phage-host cell relationship. Molecular Microbiology 57, 347-356.
135. Mmolawa, P.T., Willmore, R., Thomas, C.J. and Heuzenroeder, M.W. (2002) Temperate phages in Salmonella enterica serovar Typhimurium: implications for epidemiology. International Journal of Medical Microbiology 291, 633-644.
136. Monson, R., Foulds, I., Foweraker, J., Welch, M. and Salmond, G.P. (2011) The Pseudomonas aeruginosa generalized transducing phage φPA3 is a new member of the φKZ-like group of 'jumbo' phages, and infects model laboratory strains and clinical isolates from cystic fibrosis patients. Microbiology 157, 859-867.
137. Morgan, A.F. (1979) Transduction of Pseudomonas aeruginosa with a mutant of bacteriophage E79. Journal of Bacteriology 139, 137-140.
138. Moyer, K.E., Kimsey, H.H. and Waldor, M.K. (2001) Evidence for a rolling-circle mechanism of phage DNA synthesis from both replicative and integrated forms of CTXφ. Molecular Microbiology 41, 311-323.
139. Muniesa, M., de Simon, M., Prats, G., Ferrer, D., Panella, H. and Jofre, J. (2003) Shiga toxin 2-converting bacteriophages associated with clonal variability in Escherichia coli O157:H7 strains of human origin isolated from a single outbreak. Infection and Immunity 71, 4554-4562.
140. Muniesa, M., Blanco, J.E., de Simon, M., Serra-Moreno, R., Blanch, A.R. and Jofre, J. (2004a) Diversity of stx2 converting bacteriophages induced from Shiga-toxin-producing Escherichia coli strains isolated from cattle. Microbiology 150, 2959-2971.
141. Muniesa, M., Serra-Moreno, R. and Jofre, J. (2004b) Free Shiga toxin bacteriophages isolated from sewage showed diversity although the stx genes appeared conserved. Environmental Microbiology 6, 716-725.
142. Narita, S., Kaneko, J., Chiba, J., Piemont, Y., Jarraud, S., Etienne, J. and Kamio, Y. (2001) Phage conversion of Panton-Valentine leukocidin in Staphylococcus aureus: molecular analysis of a PVL-converting phage, φSLT. Gene 268, 195-206.
143. Neoh, H.M., Cui, L., Yuzawa, H., Takeuchi, F., Matsuo, M. and Hiramatsu, K. (2008) Mutated response regulator graR is responsible for phenotypic conversion of Staphylococcus aureus from heterogeneous vancomycinintermediate resistance to vancomycinintermediate resistance. Antimicrobial Agents and Chemotherapy 52:45-53.
144. Newton, G.J., Daniels, C., Burrows, L.L., Kropinski, A.M., Clarke, A.J. and Lam, J.S. (2001) Threecomponent-mediated serotype conversion in Pseudomonas aeruginosa by bacteriophage D3. Molecular Microbiology 39, 1237-1247.
145. Nishifuji, K., Sugai, M. and Amagai, M. (2008) Staphylococcal exfoliative toxins: "molecular scissors" of bacteria that attack the cutaneous defense barrier in mammals. Journal of Dermatological Science 49, 21-31.
146. Novick, R.P. (2006) Staphylococcal pathogenesis and pathogenicity factors: genetics and regulation. In: Fischetti, V.A. (ed.) Gram-positive Pathogens. ASM Press, Washington, DC, pp. 496-516.
147. Novick, R.P. and Subedi, A. (2007) The SaPIs: mobile pathogenicity islands of Staphylococcus. Chemical Immunology and Allergy 93, 42-57.
148. Novick, R.P., Christie, G.E. and Penades, J.R. (2010a) The phage-related chromosomal islands of Gram-positive bacteria. Nature Reviews Microbiology 8, 541-551.
149. Nübel, U., Dordel, J., Kurt, K., Strommenger, B., Westh, H., Shukla, S.K., Zemlickova, H., Leblois, R., Wirth, T., Jombart, T., Balloux, F. and Witte, W. (2010) A timescale for evolution, population expansion, and spatial spread of an emerging clone of methicillin-resistant Staphylococcus aureus. PLoS Pathogens 6, e1000855.
150. O'Brien, A.D., Newland, J.W., Miller, S.F., Holmes, R.K., Smith, H.W. and Formal, S.B. (1984) Shiga-like toxin-converting phages from Escherichia coli strains that cause hemorrhagic colitis or infantile diarrhea. Science 226, 694-696.
151. O'Loughlin, E.V. and Robins-Browne, R.M. (2001) Effect of Shiga toxin and Shiga-like toxins on eukaryotic cells. Microbes and Infection 3, 493-507.
152. Oguma, K. (1976) The stability of toxigenicity in Clostridium botulinum types C and D. Journal of General Microbiology 92, 67-75.
153. Oguma, K., Iida, H. and Shiozaki, M. (1976) Phage conversion to hemagglutinin production in Clostridium botulinum types C and D. Infection and Immunity 14, 597-602.
154. Panton, P.N., Came, M.B. and Valentine, F.C.O. (1932) Staphylococcal toxin. Lancet 1, 506-508.
155. Pantucek, R., Doskar, J., Ruzickova, V., Kaspárek, P., Orácová, E., Kvardova, V. and Rosypal, S. (2004) Identification of bacteriophage types and their carriage in Staphylococcus aureus. Archives of Virology 149, 1689-1703.
156. Pedulla, M.L., Ford, M.E., Karthikeyan, T., Houtz, J.M., Hendrix, R.W., Hatfull, G.F., Poteete, A.R., Gilcrease, E.B., Winn-Stapley, D.A. and Casjens, S.R. (2003) Corrected sequence of the bacteriophage P22 genome. Journal of Bacteriology 185, 1475-1477.
157. Perry, L.L., SanMiguel, P., Minocha, U., Terekhov, A.I., Shroyer, M.L., Farris, L.A., Bright, N., Reuhs, B.L. and Applegate, B.M. (2009) Sequence analysis of Escherichia coli O157:H7 bacteriophage φV10 and identification of a phage-encoded immunity protein that modifies the O157 antigen. FEMS Microbiology Letters 292, 182-186.
158. Petty, N.K., Foulds, I.J., Pradel, E., Ewbank, J.J. and Salmond, G.P. (2006) A generalized transducing phage (φIF3) for the genomically sequenced Serratia marcescens strain Db11: a tool for functional genomics of an opportunistic human pathogen. Microbiology 152, (Pt 6) 1701-1708.
159. Petty, N.K., Toribio, A.L., Goulding, D., Foulds, I., Thomson, N., Dougan, G. and Salmond, G.P. (2007) A generalized transducing phage for the murine pathogen Citrobacter rodentium. Microbiology 153, 2984-2988.
160. Proft, T. and Fraser, J.D. (2003) Bacterial superantigens. Clinical and Experimental Immunology 133, 299-306.
161. Proft, T., Moffatt, S.L., Berkahn, C.J. and Fraser, J.D. (1999) Identification and characterization of novel superantigens from Streptococcus pyogenes. Journal of Experimental Medicine 189, 89-102.
162. Proft, T., Sriskandan, S., Yang, L. and Fraser, J.D. (2003a) Superantigens and streptococcal toxic shock syndrome. Emerging Infectious Diseases 9, 1211-1218.
163. Proft, T., Webb, P.D., Handley, V. and Fraser, J.D. (2003b) Two novel superantigens found in both group A and group C Streptococcus. Infection and Immunity 71, 1361-1369.
164. Quinones, M., Kimsey, H.H. and Waldor, M.K. (2005) LexA cleavage is required for CTX prophage induction. Molecules and Cells 17, 291-300.
165. Quinones, M., Davis, B.M. and Waldor, M.K. (2006) Activation of the Vibrio cholerae SOS response is not required for intestinal cholera toxin production or colonization. Infection and Immunity 74, 927-930.
166. Rakonjac, J., Bennett, N.J., Spagnuolo, J., Gagic, D. and Russel, M. (2011) Filamentous bacteriophage: biology, phage display and nanotechnology applications. Current Issues in Molecular Biology 13, 51-76.
167. Rappuoli, R., Michel, J.L. and Murphy, J.R. (1983) Restriction endonuclease map of corynebacteriophage ωc tox+ isolated from the Park-Williams no. 8 strain of Corynebacterium diphtheriae. Journal of Virology 45, 524-530.
168. Recktenwald, J. and Schmidt, H. (2002) The nucleotide sequence of Shiga toxin (Stx) 2e-encoding phage φP27 is not related to other Stx phage genomes, but the modular genetic structure is conserved. Infection and Immunity 70, 1896-1908. [Erratum: 70, 4755.]
169. Rheinwald, J.G., Chakrabarty, A.M. and Gunsalus, I.C. (1973) A transmissible plasmid controlling camphor oxidation in Pseudomonas putida. Proceedings of the National Academy of Sciences USA 70, 885-889.
170. Riley, L.W., Remis, R.S., Helgerson, S.D., McGee, H.B., Wells, J.G., Davis, B.R., Hebert, R.J., Olcott, E.S., Johnson, L.M., Hargrett, N.T., Blake, P.A. and Cohen, M.L. (1983) Hemorrhagic colitis associated with a rare Escherichia coli serotype. New England Journal of Medicine 308, 681-685.
171. Roberts, M.D. and Drexler, H. (1981) Isolation and genetic characterization of T1-transducing mutants with increased transduction frequency. Virology 112, 662-669.
172. Rooijakkers, S.H., Ruyken, M., Roos, A., Daha, M.R., Presanis, J.S., Sim, R.B., van Wamel, W.J., van Kessel, K.P. and van Strijp, J.A. (2005) Immune evasion by a staphylococcal complement inhibitor that acts on C3 convertases. Nature Immunology 6, 920-927.
173. Rooijakkers, S.H., Ruyken, M., van Roon, J., van Kessel, K.P., van Strijp, J.A. and van Wamel, W.J. (2006) Early expression of SCIN and CHIPS drives instant immune evasion by Staphylococcus aureus. Cellular Microbiology 8, 1282-1293.
174. Rosendal, K., Buelow, P. and Jessen, O. (1964) Lysogen conversion in Staphylococcus aureus, to a change in the production of extracellular 'Tween'-splitting enzyme. Nature, 204, 1222-1223.
175. Sachse, S., Seidel, P., Gerlach, D., Gunther, E., Rodel, J., Straube, E. and Schmidt, K.H. (2002) Superantigen-like gene(s) in human pathogenic Streptococcus dysgalactiae, subsp equisimilis: genomic localisation of the gene encoding streptococcal pyrogenic exotoxin G (speGdys). FEMS Immunology and Medical Microbiology 34, 159-167.
176. Sakaguchi, Y., Hayashi, T., Kurokawa, K., Nakayama, K., Oshima, K., Fujinaga, Y., Ohnishi, M., Ohtsubo, E., Hattori, M. and Oguma, K. (2005) The genome sequence of Clostridium botulinum type C neurotoxinconverting phage and the molecular mechanisms of unstable lysogeny. Proceedings of the National Academy of Sciences USA 102, 17472-17477.
177. Sako, T. and Tsuchida, N. (1983) Nucleotide sequence of the staphylokinase gene from Staphylococcus aureus. Nucleic Acids Research 11, 7679-7693.
178. Sako, T., Sawaki, S., Sakurai, T., Ito, S., Yoshizawa, Y. and Kondo, I. (1983) Cloning and expression of the staphylokinase gene of Staphylococcus aureus in Escherichia coli. Molecular and General Genetics 190, 271-277.
179. Schallehn, G., Eklund, M.W. and Brandis, H. (1980) [Phage conversion of Clostridium novyi type A.] Zentralblatt für Bakteriologie A 247, 95-100 (in German).
180. Schijffelen, M.J., Boel, C.H., van Strijp, J.A. and Fluit, A.C. (2010) Whole genome analysis of a livestock-associated methicillin-resistant Staphylococcus aureus ST398 isolate from a case of human endocarditis. BMC Genomics 11, 376.
181. Scott, J., Thompson-Mayberry, P., Lahmamsi, S., King, C.J. and McShan, W.M. (2008) Phageassociated mutator phenotype in group A Streptococcus. Journal of Bacteriology 190, 6290-6301.
182. Sebaihia, M., Peck, M.W., Minton, N.P., Thomson, N.R., Holden, M.T., Mitchell, W.J., Carter, A.T., Bentley, S.D., Mason, D.R., Crossman, L., Paul, C.J., Ivens, A., Wells-Bennik, M.H., Davis, I.J., Cerdeno-Tarraga, A.M., Churcher, C., Quail, M.A., Chillingworth, T., Feltwell, T., Fraser, A., Goodhead, I., Hance, Z., Jagels, K., Larke, N., Maddison, M., Moule, S., Mungall, K., Norbertczak, H., Rabbinowitsch, E., Sanders, M., Simmonds, M., White, B., Whithead, S. and Parkhill, J. (2007) Genome sequence of a proteolytic (Group I) Clostridium botulinum strain Hall A and comparative analysis of the clostridial genomes. Genome Research 17, 1082-1092.
183. Shimizu, T., Ohta, Y. and Noda, M. (2009) Shiga toxin 2 is specifically released from bacterial cells by two different mechanisms. Infection and Immunity 77, 2813-2823.
184. Shimomura, Y., Okumura, K., Murayama, S.Y., Yagi, J., Ubukata, K., Kirikae, T. and Miyoshi-Akiyama, T. (2011) Complete genome sequencing and analysis of a Lancefield group G Streptococcus dysgalactiae subsp. equisimilis strain causing streptococcal toxic shock syndrome (STSS). BMC Genomics 12, 17.
185. Simpson, L.L. (1981) The origin, structure, and pharmacological activity of botulinum toxin. Pharmacological Reviews 33, 155-188.
186. Skarin, H., Hafstrom, T., Westerberg, J. and Segerman, B. (2011) Clostridium botulinum group III: a group with dual identity shaped by plasmids, phages and mobile elements. BMC Genomics 12, 185.
187. Smith, D.L., James, C.E., Sergeant, M.J., Yaxian, Y., Saunders, J.R., McCarthy, A.J. and Allison, H.E. (2007a) Short-tailed stx phages exploit the conserved YaeT protein to disseminate Shiga toxin genes among enterobacteria. Journal of Bacteriology 189, 7223-7233.
188. Smith, D.L., Wareing, B.M., Fogg, P.C., Riley, L.M., Spencer, M., Cox, M.J., Saunders, J.R., McCarthy, A.J. and Allison, H.E. (2007b) Multilocus characterization scheme for shiga toxin-encoding bacteriophages. Applied and Environmental Microbiology 73, 8032-8040.
189. Smith, T.J., Hill, K.K., Foley, B.T., Detter, J.C., Munk, A.C., Bruce, D.C., Doggett, N.A., Smith, L.A., Marks, J.D., Xie, G. and Brettin, T.S. (2007c) Analysis of the neurotoxin complex genes in Clostridium botulinum A1-A4 and B1 strains: BoNT/A3, /Ba4 and /B1 clusters are located within plasmids. PLoS ONE 2, e1271.
190. Staali, L., Monteil, H. and Colin, D.A. (1998) The staphylococcal pore-forming leukotoxins open Ca2+ channels in the membrane of human polymorphonuclear neutrophils. Journal of Membrane Biology 162, 209-216.
191. Stevens, D.L., Tanner, M.H., Winship, J., Swarts, R., Ries, K.M., Schlievert, P.M. and Kaplan, E. (1989) Severe group A streptococcal infections associated with a toxic shock-like syndrome and scarlet fever toxin A. New England Journal of Medcine. 321, 1-7.
192. Strockbine, N.A., Marques, L.R., Newland, J.W., Smith, H.W., Holmes, R.K. and O'Brien, A.D. (1986) Two toxin-converting phages from Escherichia coli O157:H7 strain 933 encode antigenically distinct toxins with similar biologic activities. Infection and Immunity 53, 135-140.
193. Su, L.K., Lu, C.P., Wang, Y., Cao, D.M., Sun, J.H. and Yan, Y.X. (2010) Lysogenic infection of a Shiga toxin 2-converting bacteriophage changes host gene expression, enhances host acid resistance and motility. Molecular Biology (Moscow) 44, 60-73.
194. Subedi, A., Ubeda, C., Adhikari, R.P., Penades, J.R. and Novick, R.P. (2007) Sequence analysis reveals genetic exchanges and intraspecific spread of SaPI2, a pathogenicity island involved in menstrual toxic shock. Microbiology 153, 3235-3245.
195. Sugiyama, H. (1980) Clostridium botulinum neurotoxin. Microbiological Reviews 44, 419-448.
196. Sumby, P. and Waldor, M.K. (2003) Transcription of the toxin genes present within the staphylococcal phage φSa3ms is intimately linked with the phage's life cycle. Journal of Bacteriology 185, 6841-6851.
197. Szmigielski, S., Sobiczewska, E., Prevost, G., Monteil, H., Colin, D.A. and Jeljaszewicz, J. (1998) Effect of purified staphylococcal leukocidal toxins on isolated blood polymorphonuclear leukocytes and peritoneal macrophages in vitro. Zentralblatt für Bakteriologie 288, 383-394.
198. Tarkowski, T.A., Mooney, D., Thomason, L.C. and Stahl, F.W. (2002) Gene products encoded in the ninR region of phage λ participate in Redmediated recombination. Genes to Cells 7, 351-363.
199. Teel, L.D., Melton-Celsa, A.R., Schmitt, C.K. and O'Brien, A.D. (2002) One of two copies of the gene for the activatable shiga toxin type 2d in Escherichia coli O91:H21 strain B2F1 is associated with an inducible bacteriophage. Infection and Immunity 70, 4282-4291.
200. Thierauf, A., Perez, G. and Maloy, A.S. (2009) Generalized transduction. Methods in Molecular Biology 501, 267-286.
201. Thomson, N., Baker, S., Pickard, D., Fookes, M., Anjum, M., Hamlin, N., Wain, J., House, D., Bhutta, Z., Chan, K., Falkow, S., Parkhill, J., Woodward, M., Ivens, A. and Dougan, G. (2004) The role of prophage-like elements in the diversity of Salmonella enterica serovars. Journal of Molecular Biology 339, 279-300.
202. Tianiashin, V.I., Zimin, V.I., Boronin, A.M., Tianiashin, V.I., Zimin, V.I. and Boronin, A.M. (2003) [The cotransduction of pET system plasmids by mutants of T4 and RB43 bacteriophages]. Mikrobiologiia 72, 785-791 (in Russian).
203. Todd, J., Fishaut, M., Kapral, F. and Welch, T. (1978) Toxic-shock syndrome associated with phagegroup-I staphylococci. Lancet 2, 1116-1118.
204. Toth, I.K., Perombelon, M.C.M. and Salmond, G.P.C. (1993) Bacteriophage φKP mediated generalized transduction in Erwinia carotovora subsp. carotovora. Journal of General Microbiology 139, 2705-2709.
205. Toth, I.K., Mulholland, F., Cooper, V., Bentley, S., Shih, Y.L., Perombelon, M.C.M. and Salmond, G.P.C. (1997) Generalized transduction in the potato blackleg pathogen Erwinia carotovora subsp. atroseptica by bacteriophage φM1. Microbiology 143, 2433-2438.
206. Tranter, H.S. (1990) Foodborne staphylococcal illness. Lancet 336, 1044-1046.
207. Tucker, C.P. and Heuzenroeder, M.W. (2004) ST64B is a defective bacteriophage in Salmonella enterica serovar Typhimurium DT64 that encodes a functional immunity region capable of mediating phage-type conversion. International Journal of Medical Microbiology 294, 59-63.
208. Ubeda, C., Maiques, E., Knecht, E., Lasa, I., Novick, R.P. and Penades, J.R. (2005) Antibiotic-induced SOS response promotes horizontal dissemination of pathogenicity island-encoded virulence factors in staphylococci. Molecular Microbiology 56, 836-844.
209. Ubukata, K., Konno, M. and Fujii, R. (1975) Transduction of drug resistance to tetracycline, chloramphenicol, macrolides, lincomycin and clindamycin with phages induced from Streptococcus pyogenes. Journal of Antibiotics (Tokyo) 28, 681-688.
210. Vaca, S., Perez, S., Martinez, G. and Enriquez, F. (1993) Partial genetic characterization of FIZ15 bacteriophage of Pseudomonas aeruginosa. Revista Latinoamericana de Microbiologia 35, 251-257.
211. Vaca-Pacheco, S., Paniagua-Contreras, G.L., Garcia-Gonzalez, O. and de la Garza, M. (1999) The clinically isolated FIZ15 bacteriophage causes lysogenic conversion in Pseudomonas aeruginosa PAO1. Current Microbiology 38, 239-243.
212. van der Vijver, J.C., van Es-Boon, M. and Michel, M.F. (1972) Lysogenic conversion in Staphylococcus aureus to leucocidin production. Journal of Virology 10, 318-319.
213. van Wamel, W.J., Rooijakkers, S.H., Ruyken, M., van Kessel, K.P. and van Strijp, J.A. (2006) The innate immune modulators staphylococcal complement inhibitor and chemotaxis inhibitory protein of Staphylococcus aureus are located on β-hemolysin-converting bacteriophages. Journal of Bacteriology 188, 1310-1315.
214. Vander Byl, C. and Kropinski, A.M. (2000) Sequence of the genome of Salmonella bacteriophage P22. Journal of Bacteriology 182, 6472-6481.
215. Viana, D., Blanco, J., Tormo-Mas, M.A., Selva, L., Guinane, C.M., Baselga, R., Corpa, J.M., Lasa, I., Novick, R.P., Fitzgerald, J.R. and Penades, J.R. (2010) Adaptation of Staphylococcus aureus to ruminant and equine hosts involves SaPI-carried variants of von Willebrand factorbinding protein. Molecular Microbiology 77, 1583-1594.
216. Wagner, P.L. and Waldor, M.K. (2002) Bacteriophage control of bacterial virulence. Infection and Immunity 70, 3985-3993.
217. Wagner, P.L., Neely, M.N., Zhang, X., Acheson, D.W., Waldor, M.K. and Friedman, D.I. (2001) Role for a phage promoter in Shiga toxin 2 expression from a pathogenic Escherichia coli strain. Journal of Bacteriology 183, 2081-2085.
218. Waldor, M.K. and Mekalanos, J.J. (1996) Lysogenic conversion by a filamentous phage encoding cholera toxin. Science 272, 1910-1914.
219. Wannamaker, L.W., Almquist, S. and Skjold, S. (1973) Intergroup phage reactions and transduction between group C and group A streptococci. Journal of Experimental Medicine 137, 1338-1353.
220. Weiss, B.D., Capage, M.A., Kessel, M. and Benson, S.A. (1994) Isolation and characterization of a generalized transducing phage for Xanthomonas campestris pv. campestris. Journal of Bacteriology 176, 3354-3359.
221. Wilson, G.G., Young, K.Y., Edlin, G.J. and Konigsberg, W. (1979) High-frequency generalised transduction by bacteriophage T4. Nature 280, 80-82.
222. Winkler, K.C., de Waart, J. and Grootsen, C. (1965) Lysogenic conversion of staphylococci to loss of β-toxin. Journal of General Microbiology 39, 321-333.
223. Yamaguchi, T., Hayashi, T., Takami, H., Nakasone, K., Ohnishi, M., Nakayama, K., Yamada, S., Komatsuzawa, H. and Sugai, M. (2000) Phage conversion of exfoliative toxin A production in Staphylococcus aureus. Molecular Microbiology 38, 694-705.
224. Yarwood, J.M., McCormick, J.K., Paustian, M.L., Orwin, P.M., Kapur, V. and Schlievert, P.M. (2002) Characterization and expression analysis of Staphylococcus aureus pathogenicity island 3. Implications for the evolution of staphylococcal pathogenicity islands. Journal of Biological Chemistry 277, 13138-13147.
225. Young, K.K., Edlin, G.J. and Wilson, G.G. (1982) Genetic analysis of bacteriophage T4 transducing bacteriophages. Journal of Virology 41, 345-347.
226. Zabicka, D., Mlynarczyk, A., Windyga, B. and Mlynarczyk, G. (1993) Phage-related conversion of enterotoxin A, staphylokinase and β-toxin in Staphylococcus aureus. Acta Microbiologica Polonica 42, 235-241.
227. Zou, D., Kaneko, J., Narita, S. and Kamio, Y. (2000) Prophage, φPV83-pro, carrying Panton-Valentine leukocidin genes, on the Staphylococcus aureus P83 chromosome: comparative analysis of the genome structures of φPV83-pro, φPVL, φ11, and other phages. Bioscience, Biotechnology and Biochemistry 64, 2631-2643.