Shiga toxin 2-converting bacteriophages associated with clonal variability in Escherichia coli O157:H7 strains of human origin isolated from a single outbreak

Infection and Immunity

Volumn 71, Issue 8, 2003, Pages 4554-4562

  Muniesa, Maite ^a   De Simon, Mercè ^b   Prats, Guillem ^c   Ferrer, Dolors ^b   Pañella, Helena ^d   Jofre, Juan ^a  

^a UNIVERSITY OF BARCELONA   (Spain)

^b Inst Munic de Salut Pub Barcelona   (Spain)

^c University Hospital of St Pau (Cardiology)   (Spain)

^d Servei Epidemiologia   (Spain)

Author keywords

[No Author keywords available]

Indexed keywords

BACTERIAL DNA; BACTERIOPHAGE DNA; MITOMYCIN C; SHIGA TOXIN; UNCLASSIFIED DRUG; VEROTOXIN 2;

ADULT; ARTICLE; BACTERIAL STRAIN; BACTERIAL VIRULENCE; BACTERIOPHAGE; BACTERIOPHAGE 933W; BACTERIOPHAGE LC159; BACTERIOPHAGE PHI SC370; BACTERIUM ISOLATE; CHILD; CLINICAL ARTICLE; CLONAL VARIATION; CROSS HYBRIDIZATION; DISEASE SEVERITY; DNA STRUCTURE; ENTEROCOLITIS; ESCHERICHIA COLI O157; GENE EXPRESSION REGULATION; GENE SEQUENCE; HUMAN; MORPHOLOGY; NONHUMAN; NUCLEOTIDE SEQUENCE; PRIORITY JOURNAL; SHIGA TOXIN 2 CONVERTING BACTERIOPHAGE; SPAIN; SYMPTOM;

BASE SEQUENCE; COLIPHAGES; DISEASE OUTBREAKS; DNA, VIRAL; ENTEROCOLITIS; ESCHERICHIA COLI INFECTIONS; ESCHERICHIA COLI O157; GENES, VIRAL; HUMANS; MICROSCOPY, ELECTRON; MOLECULAR SEQUENCE DATA; SHIGA-LIKE TOXIN II; SPAIN; VARIATION (GENETICS);

EID: 0043267536     PISSN: 00199567     EISSN: None     Source Type: Journal    
DOI: 10.1128/IAI.71.8.4554-4562.2003     Document Type: Article

References (34)

1. Acheson, D. W. K., and G. T. Keusch. 1996. Which Shiga toxin-producing types of Escherichia coli are important? ASM News 62:302-306.
2. Acheson, D. W. K., J. Reidl, X. Zhang, G. T. Keusch, J. J. Mekalanos, and M. K. Waldor. 1998. In vivo transduction with Shiga toxin 1-encoding phage. Infect. Immun. 66:4496-4498.
3. Akiba, M., T. Sameshima, and M. Nakazawa. 2000. Clonal turnover of enterohemorrhagic Escherichia coli O157:H7 in experimentally infected cattle. FEMS Microbiol. Lett. 194:79-83.
4. Anonymous. 2001. Brot de gastroenteritis per E. coli O157:H7 en diferents escoles de Catalunya. Bol. Epidemiolog. Cataluna 22:59-64.
5. Datz, M., C. Janetzki-Mittmann, S. Franke, F. Gunzer, H. Schmidt, and H. Karch. 1996. Analysis of the enterohemorrhagic Escherichia coli O157 DNA region containing lamboid phage gene p and Shiga-like toxin structural genes. Appl Environ Microbiol. 62:791-797.
6. Doyle, M. P. 1997. Escherichia coli O157, p. 171-191 In M. P. Doyle, L. R. Beuchat, and T. J. Montville, (ed.), Food microbiology: fundamentals and frontiers. ASM Press, Washington, D.C.
7. Friedrich, A. W., M. Bielaszewska, W. L. Zhang, M. Pulz, T. Kuczius, A. Ammon, and H. Karch. 2002. Escherichia coli harboring Shiga toxin 2 gene variants: frequency and association with clinical symptoms. J. Infect. Dis. 185:74-84.
8. Hendrix, R. W., M. C. Smith, R. N. Burns, M. E. Ford, and G. F. Hatfull. 1999. Evolutionary relationships among diverse bacteriophages and prophages: all the world's a phage. Proc. Natl. Acad. Sci. USA 96:2192-2197.
9. Hendrix, R. W., J. G. Lawrence, G. F. Hatfull, and S. Casjens. 2000. The association of IS1203 and stx and p genes in E. coli O157:H7, p. 178. In G. Duffy, P. Garvey, J. Coia, Y. Waterson, and D. A. McDowell (ed.), Pathogenicity and virulence of verotoxigenic E. coli. Proceedings of Concerted Action CT98-3935 Meeting 3. The National Food Center, Dublin, Ireland.
10. Johansen, B. K., Y. Wasteson, P. E. Granum, and S. Brynestas. 2001. Mosaic structure of Shiga-toxin-2 encoding phages isolated from Escherichia coli O157:H7 indicates frequent gene exchange between lambdoid phage genomes. Microbiology 147:1929-1936.
11. Karch, H., H. Russman, H. Schmidt, A. Schwarzkopf, and J. Hessemann. 1995. Long-term shedding and clonal turnover of enterohemorrhagic Escherichia coli O157 in diarrheal diseases. J. Clin. Microbiol. 33:1602-1605.
12. Kohler, B., H. Karch, and H. Schmidt. 2000. Antibacterials that are used as growth promoters in animal husbandry can affect the production of Shigatoxin-2-converting bacteriophages and Shiga toxin 2 from Escherichia coli strains. Microbiology 146:1085-1090.
13. Makino, K., K. Yokohama, Y. Kubota, et al. 1999. Complete nucleotide sequence of the prophage VT2.Sakai carrying the verotoxin 2 genes of the enterohemorrhagic Escherichia coli O157:H7 derived from the Sakai outbreak. Genes Genet. Syst. 74:227-239.
14. Matsushiro, A., K. Sato, H. Miyamoto, T. Yamamura, and T. Honda. 1999. Induction of prophages of enterohemorrhagic Escherichia coli O157:H7 with norfloxacin. J. Bacteriol. 181:2257-2260.
15. McDonough, M. A., and J. R. Butterton. 1999. Spontaneous tandem amplification and deletion of the Shiga toxin operon in Shigella dysenteriae 1. Mol. Microbiol. 34:1058-1069.
16. Mühldorfer, I., J. Hacker, G. T., Keusch, D. W. Acheson, H. Tschäpe, A. V. Kane, A. Ritter, T. Ölschläger, and A. Donohue-Rolfe. 1996. Regulation of the Shiga-like toxin II operon in Escherichiacoli. Infect. Immun. 64:495-502.
17. Muniesa, M., and J. Jofre. 1998. Abundance in sewage of bacteriophages that infect E. coli O157:H7 and that carry the Shiga toxin 2 gene. Appl. Environ. Microbiol. 64:2443-2448.
18. Muniesa, M., J. Recktenwald, M. Bielaszewska, H. Karch, and H. Schmidt. 2000. Characterization of a Shiga toxin 2e-converting bacteriophage from an Escherichia coli strain of human origin. Infect. Immun. 68:4850-4855.
19. Nataro, J. P., and J. J. Kaper. 1998. Diarrheagenic Escherichia coli. Clin. Microbiol. Rev. 11:142-201.
20. Neely, M. N., and D. I. Friedman. 1998. Functional and genetic analysis of regulatory regions of coliphage H-19B: location of Shiga-like toxin and lysis genes suggest a role for phage functions in toxin release. Mol. Microbiol. 28:1255-1268.
21. O'Brien, A. D., J. W. Newland, S. F. Miller, R. K. Holmes, H. Williams Smith, and S. B. Formal. 1984. Shiga like toxin-converting phages from Escherichia coli strains that cause hemorrhagic colitis or infantile diarrhea. Science 226:694-696.
22. Paton, A. W., and J. C. Paton. 1998. Pathogenesis and diagnosis of Shiga toxin-producing Escherichia coli infections. Clin. Microbiol. Rev. 11:450-479.
23. Plunkett, G., D. J. Rose, T. J. Durfee, and F. R. Blattner. 1999. Sequence of Shiga toxin 2 phage 933 W from Escherichia coli O157:H7: Shiga toxin as a phage late-gene product. J. Bacteriol. 181:1767-1778.
24. Rüssman, H., H. Schmidt, A. Caprioli, and H. Karch. 1994. Highly conserved B subunits genes of Shiga-like toxin II variants found in Escherichia coli O157 strains. FEMS Microbiol. Lett. 118:335-340.
25. Sambrook, J., and D. W. Russell. 2001. Molecular cloning: a laboratory manual, 3rd ed. Cold Spring Harbor Laboratory, Cold Spring Harbor, N.Y.
26. Schmidt, H., M. Bielaszewska, and H. Karch. 1999. Transduction of enteric Escherichia coli isolates with a derivative of Shiga-toxin 2-encoding bacteriophage φ3538 isolated from E. coli O157:H7. Appl. Environ. Microbiol. 65:3855-3861.
27. Stewart, D. S., M. L. Tortorello, and S. M. Gendel. 1998. Evaluation of DNA preparation techniques for detection of the SLT-1 gene of Escherichia coli O157:H7 in bovine faeces using the polymerase chain reaction. Lett. Appl. Microbiol. 26:93-97.
28. Strauch, E., R. Lurz, and L. Beutin. 2001. Characterization of a Shiga toxin-encoding temperate bacteriophage of Shigella sonnei. Infect. Immun. 69:7588-7595.
29. Teel., L. D., A. R. Melton-Celsa, C. K. Schmitt, and A. D. O'Brien. 2002. One of two copies of the gene for the activatable Shiga toxin type 2d in Escherichia coli O91:H21 strain B2F1 is associated with an inducible bacteriophage. Infect. Immun. 70:4282-4291.
30. Unkmeir, A., and H. Schmidt. 2000. Structural analysis of phage-borne stx genes and their flanking sequences in Shiga toxin-producing Escherichia coli and Shigella dysenteriae type 1 strains. Infect. Immun. 68:4856-4864.
31. Wagner, P. L., D. W. K. Acheson, and M. K. Waldor. 1999. Isogenic lysogens of diverse Shiga toxin 2-encoding bacteriophages produce markedly different amounts of Shiga toxin. Infect. Immun. 67:6710-6714.
32. Wagner, P. L., M. N. Neely, X. Zhang, D. W. K. Acheson, M. K. Waldor, and D. I. Friedman. 2001. Role for a phage promoter in Shiga toxin 2 expression from a pathogenic Escherichia coli strain. J. Bacteriol. 183:2081-2085.
33. Watarai, M., T. Sato, M. Kobayashi, T. Shimizu, S. Yamakasi, T. Tobe, C. Sasakawa, and W. Takeda. 1998. Identification and characterization of a newly isolated Shiga toxin 2-converting phage from Shiga toxin-producing Escherichia coli. Infect. Immun. 66:4100-4107.
34. Yokoyama, K., K. Makino, Y. Kubota, et al. 2000. Complete nucleotide sequence of the prophage VT1-Sakai carrying the Shiga toxin 1 genes of the enterohemorrhagic Escherichia coli O157:H7 strain derived from the Sakai outbreak. Gene 258:127-139.