Rembrandt: Helping personalized medicine become a reality through integrative translational research

Molecular Cancer Research

Volumn 7, Issue 2, 2009, Pages 157-167

  Madhavan, Subha ^a   Zenklusen, Jean Claude ^a   Kotliarov, Yuri ^a   Sahni, Himanso ^b   Fine, Howard A ^a   Buetow, Kenneth ^a  

^a NATIONAL CANCER INSTITUTE   (United States)

^b SCIENCE APPLICATIONS INTERNATIONAL CORPORATION   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

BIOLOGICAL MARKER;

ARTICLE; BRAIN TUMOR; DATA BASE; GENE EXPRESSION; GENE NUMBER; GENOMICS; GLIOMA; INFORMATION PROCESSING; INFORMATION SCIENCE; MEDICAL INFORMATION SYSTEM; MEDICAL RESEARCH; PRIORITY JOURNAL; REPOSITORY OF MOLECULAR BRAIN NEOPLASIA DATA;

BRAIN NEOPLASMS; COMPUTATIONAL BIOLOGY; DATABASES, GENETIC; GENE EXPRESSION PROFILING; GENOME, HUMAN; GENOMICS; HUMANS; OLIGONUCLEOTIDE ARRAY SEQUENCE ANALYSIS; SURVIVAL RATE;

EID: 61349128532     PISSN: 15417786     EISSN: None     Source Type: Journal    
DOI: 10.1158/1541-7786.MCR-08-0435     Document Type: Article

References (17)

1. Cancer Statistics Branch, NIH. Cancer survival rates. In: Harras A, editor. Cancer: rates & risks. Washington (DC): U.S. Department of Health & Human Services, NIH; 1996. p. 28-34.
2. Nutt CL, Mani DR, Betensky RA, et al. Gene expression-based classification of malignant gliomas correlates better with survival than histological classification. Cancer Res 2003;63:1602-7.
3. Mischel PS, Shai R, Shi T, et al. Identification of molecular subtypes of glioblastoma by gene expression profiling. Oncogene 2003;22:2361-73.
4. Phillips HS, Kharbanda S, Chen R, et al. Molecular subclasses of high-grade glioma predict prognosis, delineate a pattern of disease progression, and resemble stages in neurogenesis. Cancer Cell 2006;9:157-73.
5. Nigro JM, Misra A, Zhang L, et al. Integrated array-comparative genomic hybridization and expression array profiles identify clinically relevant molecular subtypes of glioblastoma. Cancer Res 2005;65:1678-86.
6. Louis DN, Ohgaki H, Wiestler OD, et al. The 2007 WHO classification of tumours of the central nervous system. Acta Neuropathol (Berl) 2007;114:97-109.
7. Miller CL, Diglisic S, Leister F, Webster M, Yolken RH. Evaluating RNA status for RT-PCR in extracts of postmortem human brain tissue. Biotechniques 2004;36:628-33.
8. Matsuzaki H, Dong S, Loi H, et al. Genotyping over 100,000 SNPs on a pair of oligonucleotide arrays. Nat Methods 2004;1:109-11.
9. Lee J, Kotliarova S, Kotliarov Y, et al. Tumor stem cells derived from glioblastomas cultured in bFGF and EGF more closely mirror the phenotype and genotype of primary tumors than do serum-cultured cell lines. Cancer Cell 2006;9:391-403.
10. Galli R, Binda E, Orfanelli U, et al. Isolation and characterization of tumorigenic, stem-like neural precursors from human glioblastoma. Cancer Res 2004;64:7011-21.
11. Lee J, Son MJ, Woolard K, et al. Epigenetic-mediated dysfunction of the bone morphogenetic protein pathway inhibits differentiation of glioblastoma-initiating cells. Cancer Cell 2008;13:69-80.
12. Kaplan EL, Meier P. Nonparametric estimation from incomplete observations. J Am Stat Assoc 1958;53:457-81.
13. Reich M, Liefeld T, Gould J, Lerner J, Tamayo P, Mesirov JP. GenePattern 2.0. Nat Genet 2006;38:500-1.
14. Sun L, Hui AM, Su Q, et al. Neuronal and glioma-derived stem cell factor induces angiogenesis within the brain. Cancer Cell 2006;9:287-300.
15. Phillips J, Chilukuri R, Fragoso G, Warzel D, Covitz PA. The caCORE Software Development Kit: streamlining construction of interoperable biomedical information services. BMC Med Inform Decis Mak2006;6:2.
16. Oster S, Langella S, Hastings S, et al. caGrid 1.0: an enterprise Grid infrastructure for biomedical research. J Am Med Inform Assoc 2008;15:138-49.
17. McLendon R, Friedman A, Bigner D, et al. Comprehensive genomic characterization defines human glioblastoma genes and core pathways. Nature 2008;455:1061-8.