Cholecalciferol (vitamin D3) inhibits growth and invasion by up-regulating nuclear receptors and 25-hydroxylase (CYP27A1) in human prostate cancer cells

Clinical and Experimental Metastasis

Volumn 22, Issue 3, 2005, Pages 275-284

  Tokar, Erik J ^a   Webber, Mukta M ^a  

^a MICHIGAN STATE UNIVERSITY   (United States)

Author keywords

25 hydroxylase; Cholecalciferol; CYP27A1; Invasion; MMPs; Prostate cancer; Vitamin D

Indexed keywords

25 HYDROXYLASE; CELL NUCLEUS RECEPTOR; COLECALCIFEROL; OXYGENASE; UNCLASSIFIED DRUG; VIMENTIN; ANDROGEN RECEPTOR; CALCITRIOL; CALCITRIOL RECEPTOR; CELL RECEPTOR; CHOLESTANETRIOL 26 MONOOXYGENASE; CYP27A1 PROTEIN, HUMAN; GELATINASE A; GELATINASE B; RETINOID X RECEPTOR; STEROID MONOOXYGENASE;

ARTICLE; CANCER CELL; CANCER INHIBITION; CANCER INVASION; CATALYSIS; CELL MOTILITY; CHEMOTAXIS; DRUG EFFECT; DRUG MECHANISM; DRUG METABOLISM; HUMAN; HUMAN CELL; MALIGNANT TRANSFORMATION; PROSTATE CANCER; RECEPTOR UPREGULATION; TUMOR DIFFERENTIATION; BIOSYNTHESIS; CELL MOTION; CELL PROLIFERATION; CLONOGENIC ASSAY; COMPARATIVE STUDY; DOSE RESPONSE; MALE; METABOLISM; METHODOLOGY; PATHOLOGY; PROSTATE TUMOR; TUMOR CELL LINE;

CALCITRIOL; CELL LINE, TUMOR; CELL MOVEMENT; CELL PROLIFERATION; CHEMOTAXIS; CHOLECALCIFEROL; COLONY-FORMING UNITS ASSAY; CYTOCHROME P-450 CYP27A1; DOSE-RESPONSE RELATIONSHIP, DRUG; HUMANS; MALE; MATRIX METALLOPROTEINASE 2; MATRIX METALLOPROTEINASE 9; NEOPLASM INVASIVENESS; PROSTATIC NEOPLASMS; RECEPTORS, ANDROGEN; RECEPTORS, CALCITRIOL; RECEPTORS, CYTOPLASMIC AND NUCLEAR; RETINOID X RECEPTORS; STEROID HYDROXYLASES; VIMENTIN;

EID: 24744447722     PISSN: 02620898     EISSN: None     Source Type: Journal    
DOI: 10.1007/s10585-005-8393-z     Document Type: Article

References (40)

1. EJ Tokar MM. Webber 2005 Chemoprevention of human prostate cancer by cholecalciferol (vitamin D3): 25-hydroxylase (CYP27A1) in human prostate epithelial cells Clin Exp Metastasis 22 265 73 (this issue)
2. CL Hanchette GG Schwartz 1992 Geographic patterns of prostate cancer mortality Cancer 70 2861 9
3. GG Schwartz BS Hulka 1990 Is vitamin D deficiency a risk factor for prostate cancer? (Hypothesis) Anticancer Res 10 1307 12
4. Webber MM, Weiner SM, Rehman SMM, et al. Carcinoma of the prostate: Geographic distribution and risk factors, In Webber MM (ed) in Vitro Models for Cancer Research. Boca Raton: CRC Press 1988; 5: 3-24
5. MH Ahonen L Tenkanen L Teppo 2000 Prostate cancer risk and prediagnostic serum 25-hydroxyvitamin D levels (Finland) Cancer Causes Control 11 847 52
6. EH Corder HA Guess BS Hulka 1993 Vitamin D and prostate cancer: A prediagnostic study with stored sera Cancer Epidemiol Biomarkers Prev 2 467 72
7. MF Holick D Vitamin 2002 The underappreciated D-lightful hormone that is important for skeletal and cellular health Curr Opin Endocrinol Diabetes 9 87 98
8. D Feskanisch J Ma CS Fuchs 2004 Plasma vitamin D metabolites and risk of colorectal cancer in women Cancer Epidemiol Biomarkers Prev 13 1502 08
9. PR Holt N Arber B Halmos 2002 Colonic epithelial cell proliferation decreases with increasing levels of serum 25-hydroxy vitamin D Cancer Epidemiol Biomarkers Prev 11 113 9
10. 3 from sunlight may improve the prognosis of breast-, colon-, and prostate cancer (Norway) Cancer Causes Control 15 149 58
11. 5 J Natl Cancer Inst 92 1836 40
12. X Wang NM Ponzio GP Studzinski 1997 Long-term exposure of HL60 cells to 1,25-dihydroxyvitamin D3 reduces their tumorigenicity A model for cancer chemoprevention Proc Soc Exper Biol Med 215 399 404
13. J Kovi MY Heshmat 1973 Incidence of cancer in negroes in Washington, D.C. and selected African cities Am J Epidemiol 96 401 13
14. 3 Cancer Res 52 515 20
15. 3 in seven human prostatic carcinoma cell lines Clin Cancer Res 1 997 1003
16. 3 inhibits prostate cancer cell growth by androgen-dependent and androgen-independent mechanisms Endocrinology 141 2548 56
17. 3 (calcitriol) inhibits the invasiveness of human prostate cancer cells Cancer Epidemiol Biomarkers Prev 6 727 32
18. 2 as therapeutic agents for prostate cancer Clin Cancer Res 6 901 8
19. S de Vos S Holden D Heber 1997 Effects of potent vitamin D3 analogs on clonal proliferation of human prostate cancer cell lines Prostate 31 77 83
20. GG Schwartz LW Whitlach TC Chen 1998 Human prostate cells synthesize 1,25-dihydroxyvitamin D3 from 25-hydroxyvitamin D3 Cancer Epidemiol Biomarkers Prev 7 391 95
21. MM Webber D Bello-DeOcampo S Quader 1999 Modulation of the malignant phenotype of human prostate cancer cells by N-(4-hydroxyphenyl)retinamide (4-HPR) Clin Exp Metastasis 17 255 63
22. D Bello MM Webber HK Kleinman 1997 Androgen responsive adult human prostatic epithelial cell lines immortalized by human papillomavirus 18 Carcinogenesis 18 1215 23
23. MM Webber D Bello HK Kleinman 1997 Acinar differentiation by non-malignant immortalized human prostatic epithelial cells and its loss by malignant cells Carcinogenesis 18 1225 31
24. MM Webber STA Quader HK Kleinman 2001 Human cell lines as an in vitro/in vivo model for prostate carcinogenesis and progression Prostate 47 1 13
25. 3 or UVB radiation in keratinocytes of human skin equivalents-a preliminary study Arch Dermatol Res 291 507 10
26. STA Quader D Bello-DeOcampo DE Williams 2001 Evaluation of the chemopreventive potential of retinoids using a novel in vitro human prostate carcinogenesis model Mut Res 496 153 61
27. R Montironi G Lucarini C Castaldini 1996 Immunohistochemical evaluation of type IV collagenase (72-kd metalloproteinase) in prostatic intraepithelial neoplasia Anticancer Res 16 2057 62
28. M Stearns ME. Stearns 1996 Evidence for increased activated metalloproteinase 2 (MMP-2a) expression associated with human prostate cancer progression Oncol Res 8 69 75
29. 3 and its analogues down-regulate cell invasion-associated proteases in cultured malignant cells Cell Growth Different 11 221 9
30. A Waghray MM Webber 1995 Retinoic acid modulates extracellular urokinase-type plasminogen activator activity in DU-145 human prostatic carcinoma cells Clin Cancer Res 1 747 53
31. SH Lang C Hyde IN Reid 2002 Enhanced expression of vimentin in motile prostate cell lines in poorly differentiated and metastatic prostate carcinoma Prostate 52 253 63
32. D Krill P DeFlavia R Dhir 2001 Expression patterns of vitamin D receptor in human prostate J Cell Biochem 82 566 72
33. K Prüfer J Barsony 2002 Retinoid X receptor dominates the nuclear import and export of the unliganded vitamin D receptor Mol Endocrinol 16 1738 51
34. Y Lotan XC Xu M Shalev 2000 Differential expression of nuclear retinoid receptors in normal and malignant prostates J Clin Oncol 18 116 21
35. DD Kephart PG Walfish H DeLuca 1996 Retinoid X receptor isotype identity directs human vitamin D receptor heterodimer transactivation from the 24-hydroxylase vitamin D response element in yeast Mol Endocrinol 10 408 19
36. LW Whitlatch MV Young GG Schwartz 2002 25-hydroxyvitamin D-1α-hydroxylase activity is diminished in human prostate cancer cells and is enhanced by gene transfer J Steroid Biochem Mol Biol 81 135 40
37. 2 Prostate 55 159 167
38. TM Beer KM Hough M Garzotto 2001 Weekly high-dose calcitriol and docetaxel in advanced prostate cancer Sem Oncol 28 49 55
39. JR Muindi Y Peng DM Potter 2002 Pharmacokinetics of high-dose oral calcitriol: results from a phase I trial of calcitriol and paclitaxel Clin Pharmacol Ther 72 648 59
40. 2 in the treatment of advanced androgen-independent prostate cancer Clin Cancer Res 9 4077 83