메뉴 건너뛰기




Volumn 11, Issue 1, 2013, Pages

Connexin43 mediates NF-κB signalling activation induced by high glucose in GMCs: Involvement of c-Src

Author keywords

c Src; Connexin43; Diabetic nephropathy; Fibronectin; Inflammation; NF B signalling

Indexed keywords

4 AMINO 7 TERT BUTYL 5 (4 CHLOROPHENYL)PYRAZOLO[3,4 D]PYRIMIDINE; CONNEXIN 43; FIBRONECTIN; GLUCOSE; I KAPPA B ALPHA; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; INTERCELLULAR ADHESION MOLECULE 1; PROTEIN TYROSINE KINASE; TRANSCRIPTION FACTOR RELA; TRANSFORMING GROWTH FACTOR BETA1;

EID: 84878245972     PISSN: None     EISSN: 1478811X     Source Type: Journal    
DOI: 10.1186/1478-811X-11-38     Document Type: Article
Times cited : (42)

References (47)
  • 1
    • 0037407520 scopus 로고    scopus 로고
    • Extracellular matrix metabolism in diabetic nephropathy
    • DOI 10.1097/01.ASN.0000065640.77499.D7
    • Extracellular matrix metabolism in diabetic nephropathy. Mason RM, Wahab NA, J Am Soc Nephrol 2003 14 1358 1373 10.1097/01.ASN.0000065640.77499.D7 12707406 (Pubitemid 36519197)
    • (2003) Journal of the American Society of Nephrology , vol.14 , Issue.5 , pp. 1358-1373
    • Mason, R.M.1    Wahab, N.A.2
  • 2
    • 84858307317 scopus 로고    scopus 로고
    • Signaling mechanisms in the regulation of renal matrix metabolism in diabetes
    • 22454628
    • Signaling mechanisms in the regulation of renal matrix metabolism in diabetes. Mariappan MM, Exp Diabetes Res 2012 2012 749812 22454628
    • (2012) Exp Diabetes Res , vol.2012 , pp. 749812
    • Mariappan, M.M.1
  • 3
    • 26944433131 scopus 로고    scopus 로고
    • Linking metabolism and immunology: Diabetic nephropathy is an inflammatory disease
    • DOI 10.1681/ASN.2005040393
    • Linking metabolism and immunology: diabetic nephropathy is an inflammatory disease. Tuttle KR, J Am Soc Nephrol 2005 16 1537 1538 10.1681/ASN.2005040393 15872083 (Pubitemid 41716459)
    • (2005) Journal of the American Society of Nephrology , vol.16 , Issue.6 , pp. 1537-1538
    • Tuttle, K.R.1
  • 5
    • 41049098623 scopus 로고    scopus 로고
    • Urinary excretion of proinflammatory cytokines and transforming growth factor beta at early stages of diabetic nephropathy
    • 19143193
    • Urinary excretion of proinflammatory cytokines and transforming growth factor beta at early stages of diabetic nephropathy. Bondar IA, Klimontov VV, Nadeev AP, Ter Arkh 2008 80 52 56 19143193
    • (2008) Ter Arkh , vol.80 , pp. 52-56
    • Bondar, I.A.1    Klimontov, V.V.2    Nadeev, A.P.3
  • 6
    • 21244505435 scopus 로고    scopus 로고
    • Nuclear factor-κB activation in diabetic rat kidney: Evidence for involvement of P-selectin in diabetic nephropathy
    • DOI 10.1620/tjem.206.163
    • Nuclear factor-kappa B activation in diabetic rat kidney: evidence for involvement of P-selectin in diabetic nephropathy. Iwamoto M, Mizuiri S, Arita M, Hemmi H, Tohoku J Exp Med 2005 206 163 171 10.1620/tjem.206.163 15888973 (Pubitemid 40895046)
    • (2005) Tohoku Journal of Experimental Medicine , vol.206 , Issue.2 , pp. 163-171
    • Iwamoto, M.1    Mizuiri, S.2    Arita, M.3    Hemmi, H.4
  • 8
    • 34248994869 scopus 로고    scopus 로고
    • Gap junctional complexes: From partners to functions
    • DOI 10.1016/j.pbiomolbio.2007.03.010, PII S0079610707000089, Gap junction channels: from protein genes to diseases
    • Gap junctional complexes: from partners to functions. Herve JC, Bourmeyster N, Sarrouilhe D, Duffy HS, Prog Biophys Mol Biol 2007 94 29 65 10.1016/j.pbiomolbio.2007.03.010 17507078 (Pubitemid 46782980)
    • (2007) Progress in Biophysics and Molecular Biology , vol.94 , Issue.1-2 , pp. 29-65
    • Herve, J.-C.1    Bourmeyster, N.2    Sarrouilhe, D.3    Duffy, H.S.4
  • 9
    • 0035991948 scopus 로고    scopus 로고
    • Gap junctions: Structure and function (review)
    • DOI 10.1080/09687680210139839
    • Gap junctions: structure and function (Review). Evans WH, Martin PE, Mol Membr Biol 2002 19 121 136 10.1080/09687680210139839 12126230 (Pubitemid 34753316)
    • (2002) Molecular Membrane Biology , vol.19 , Issue.2 , pp. 121-136
    • Evans, W.H.1    Martin, P.E.M.2
  • 10
    • 36349020799 scopus 로고    scopus 로고
    • Pathophysiological roles of gap junction in glomerular mesangial cells
    • DOI 10.1007/s00232-007-9023-2
    • Pathophysiological roles of gap junction in glomerular mesangial cells. Yao J, Zhu Y, Morioka T, Oite T, Kitamura M, J Membr Biol 2007 217 123 130 10.1007/s00232-007-9023-2 17623230 (Pubitemid 350160000)
    • (2007) Journal of Membrane Biology , vol.217 , Issue.1-3 , pp. 123-130
    • Yao, J.1    Zhu, Y.2    Morioka, T.3    Oite, T.4    Kitamura, M.5
  • 13
    • 79960929748 scopus 로고    scopus 로고
    • Altered gap junctional communication and renal haemodynamics in Zucker fatty rat model of type 2 diabetes
    • 10.1007/s00125-011-2175-8 21573906
    • Altered gap junctional communication and renal haemodynamics in Zucker fatty rat model of type 2 diabetes. Takenaka T, Inoue T, Okada H, Ohno Y, Miyazaki T, Chaston DJ, Hill CE, Suzuki H, Diabetologia 2011 54 2192 2201 10.1007/s00125-011-2175-8 21573906
    • (2011) Diabetologia , vol.54 , pp. 2192-2201
    • Takenaka, T.1    Inoue, T.2    Okada, H.3    Ohno, Y.4    Miyazaki, T.5    Chaston, D.J.6    Hill, C.E.7    Suzuki, H.8
  • 14
    • 84863011181 scopus 로고    scopus 로고
    • High glucose-induced hypertrophy of mesangial cells is reversed by connexin43 overexpression via PTEN/Akt/mTOR signaling
    • 10.1093/ndt/gfr265 21633095
    • High glucose-induced hypertrophy of mesangial cells is reversed by connexin43 overexpression via PTEN/Akt/mTOR signaling. Liu L, Hu X, Cai GY, Lv Y, Zhuo L, Gao JJ, Cui SY, Feng Z, Fu B, Chen XM, Nephrol Dial Transplant 2012 27 90 100 10.1093/ndt/gfr265 21633095
    • (2012) Nephrol Dial Transplant , vol.27 , pp. 90-100
    • Liu, L.1    Hu, X.2    Cai, G.Y.3    Lv, Y.4    Zhuo, L.5    Gao, J.J.6    Cui, S.Y.7    Feng, Z.8    Fu, B.9    Chen, X.M.10
  • 15
    • 33744484067 scopus 로고    scopus 로고
    • Role of connexin43-interacting proteins at gap junctions
    • DOI 10.1159/000092561, Cardiac Gap Junctions
    • Role of connexin43-interacting proteins at gap junctions. Giepmans BN, Adv Cardiol 2006 42 41 56 16646583 (Pubitemid 43805856)
    • (2006) Advances in Cardiology , vol.42 , pp. 41-56
    • Giepmans, B.N.G.1
  • 16
    • 0035896527 scopus 로고    scopus 로고
    • Interaction of c-Src with gap junction protein connexin-43: Role in the regulation of cell-cell communication
    • 10.1074/jbc.M005847200 11124251
    • Interaction of c-Src with gap junction protein connexin-43: role in the regulation of cell-cell communication. Giepmans BN, Hengeveld T, Postma FR, Moolenaar WH, J Biol Chem 2001 276 8544 8549 10.1074/jbc.M005847200 11124251
    • (2001) J Biol Chem , vol.276 , pp. 8544-8549
    • Giepmans, B.N.1    Hengeveld, T.2    Postma, F.R.3    Moolenaar, W.H.4
  • 17
    • 59349109991 scopus 로고    scopus 로고
    • Molecular reorganization of Cx43, Zo-1 and Src complexes during the endocytosis of gap junction plaques in response to a non-genomic carcinogen
    • 10.1242/jcs.033373 19033388
    • Molecular reorganization of Cx43, Zo-1 and Src complexes during the endocytosis of gap junction plaques in response to a non-genomic carcinogen. Gilleron J, Fiorini C, Carette D, Avondet C, Falk MM, Segretain D, Pointis G, J Cell Sci 2008 121 4069 4078 10.1242/jcs.033373 19033388
    • (2008) J Cell Sci , vol.121 , pp. 4069-4078
    • Gilleron, J.1    Fiorini, C.2    Carette, D.3    Avondet, C.4    Falk, M.M.5    Segretain, D.6    Pointis, G.7
  • 19
    • 79952903211 scopus 로고    scopus 로고
    • Activation of Src mediates PDGF-induced Smad1 phosphorylation and contributes to the progression of glomerulosclerosis in glomerulonephritis
    • 10.1371/journal.pone.0017929 21445358
    • Activation of Src mediates PDGF-induced Smad1 phosphorylation and contributes to the progression of glomerulosclerosis in glomerulonephritis. Mima A, Abe H, Nagai K, Arai H, Matsubara T, Araki M, Torikoshi K, Tominaga T, Iehara N, Fukatsu A, et al. PLoS One 2011 6 17929 10.1371/journal.pone.0017929 21445358
    • (2011) PLoS One , vol.6 , pp. 517929
    • Mima, A.1    Abe, H.2    Nagai, K.3    Arai, H.4    Matsubara, T.5    Araki, M.6    Torikoshi, K.7    Tominaga, T.8    Iehara, N.9    Fukatsu, A.10
  • 20
    • 77955143584 scopus 로고    scopus 로고
    • An angiotensin II- and NF-kappa B-dependent mechanism increases connexin 43 in murine arteries targeted by renin-dependent hypertension
    • 10.1093/cvr/cvq031 20110337
    • An angiotensin II- and NF-kappa B-dependent mechanism increases connexin 43 in murine arteries targeted by renin-dependent hypertension. Alonso F, Krattinger N, Mazzolai L, Simon A, Waeber G, Meda P, Haefliger JA, Cardiovasc Res 2010 87 166 176 10.1093/cvr/cvq031 20110337
    • (2010) Cardiovasc Res , vol.87 , pp. 166-176
    • Alonso, F.1    Krattinger, N.2    Mazzolai, L.3    Simon, A.4    Waeber, G.5    Meda, P.6    Haefliger, J.A.7
  • 21
    • 33750556235 scopus 로고    scopus 로고
    • The TLR3 ligand polyI:C downregulates connexin 43 expression and function in astrocytes by a mechanism involving the NF-κB and PI3 kinase pathways
    • DOI 10.1002/glia.20418
    • The TLR3 ligand polyI: C downregulates connexin43 expression and function in astrocytes by a mechanism involving the NF-kappa B and P13 kinase pathways. Zhao Y, Rivieccio MA, Lutz S, Scemes E, Brosnan CF, Glia 2006 54 775 785 10.1002/glia.20418 16958087 (Pubitemid 44671983)
    • (2006) GLIA , vol.54 , Issue.8 , pp. 775-785
    • Zhao, Y.1    Rivieccio, M.A.2    Lutz, S.3    Scemes, E.4    Brosnan, C.F.5
  • 22
    • 0013265232 scopus 로고    scopus 로고
    • C-Src-dependent tyrosine phosphorylation of IKKβ is involved in tumor necrosis factor-α-induced intercellular adhesion molecule-1 expression
    • DOI 10.1074/jbc.M208521200
    • c-Src-dependent tyrosine phosphorylation of IKK beta is involved in tumor necrosis factor-alpha-induced intercellular adhesion molecule-1 expression. Huang WC, Chen JJ, Chen CC, J Biol Chem 2003 278 9944 9952 10.1074/jbc. M208521200 12645577 (Pubitemid 36800499)
    • (2003) Journal of Biological Chemistry , vol.278 , Issue.11 , pp. 9944-9952
    • Huang, W.-C.1    Chen, J.-J.2    Chen, C.-C.3
  • 23
    • 0037449777 scopus 로고    scopus 로고
    • Tyrosine phosphorylation of IκBα activates NFκB through a redox-regulated and c-Src-dependent mechanism following hypoxia/reoxygenation
    • DOI 10.1074/jbc.M206718200
    • Tyrosine phosphorylation of I kappa B alpha activates NF kappa B through a redox-regulated and c-Src-dependent mechanism following hypoxia/reoxygenation. Fan CG, Li Q, Ross D, Engelhardt JF, J Biol Chem 2003 278 2072 2080 10.1074/jbc.M206718200 12429743 (Pubitemid 36801452)
    • (2003) Journal of Biological Chemistry , vol.278 , Issue.3 , pp. 2072-2080
    • Fan, C.1    Li, Q.2    Ross, D.3    Engelhardt, J.F.4
  • 24
    • 84865293359 scopus 로고    scopus 로고
    • Polydatin ameliorates experimental diabetes-induced fibronectin through inhibiting the activation of NF-kappaB signaling pathway in rat glomerular mesangial cells
    • 10.1016/j.mce.2012.06.008 22732364
    • Polydatin ameliorates experimental diabetes-induced fibronectin through inhibiting the activation of NF-kappaB signaling pathway in rat glomerular mesangial cells. Xie X, Peng J, Huang K, Huang J, Shen X, Liu P, Huang H, Mol Cell Endocrinol 2012 362 183 193 10.1016/j.mce.2012.06.008 22732364
    • (2012) Mol Cell Endocrinol , vol.362 , pp. 183-193
    • Xie, X.1    Peng, J.2    Huang, K.3    Huang, J.4    Shen, X.5    Liu, P.6    Huang, H.7
  • 25
    • 24044554201 scopus 로고    scopus 로고
    • Connexin 43 interacts with zona occludens-1 and -2 proteins in a cell cycle stage-specific manner
    • DOI 10.1074/jbc.M506799200
    • Connexin 43 interacts with zona occludens-1 and -2 proteins in a cell cycle stage-specific manner. Singh D, Solan JL, Taffet SM, Javier R, Lampe PD, J Biol Chem 2005 280 30416 30421 10.1074/jbc.M506799200 15980428 (Pubitemid 41216225)
    • (2005) Journal of Biological Chemistry , vol.280 , Issue.34 , pp. 30416-30421
    • Singh, D.1    Solan, J.L.2    Taffet, S.M.3    Javier, R.4    Lampe, P.D.5
  • 26
    • 26944480830 scopus 로고    scopus 로고
    • Intercellular adhesion molecule-1 deficiency is protective against nephropathy in type 2 diabetic db/db mice
    • DOI 10.1681/ASN.2004070612
    • Intercellular adhesion molecule-1 deficiency is protective against nephropathy in type 2 diabetic db/db mice. Chow FY, Nikolic-Paterson DJ, Ozols E, Atkins RC, Tesch GH, J Am Soc Nephrol 2005 16 1711 1722 10.1681/ASN. 2004070612 15857924 (Pubitemid 41716477)
    • (2005) Journal of the American Society of Nephrology , vol.16 , Issue.6 , pp. 1711-1722
    • Chow, F.Y.1    Nikolic-Paterson, D.J.2    Ozols, E.3    Atkins, R.C.4    Tesch, G.H.5
  • 27
    • 0141866840 scopus 로고    scopus 로고
    • Intercellular adhesion molecule-1-deficient mice are resistant against renal injury after induction of diabetes
    • DOI 10.2337/diabetes.52.10.2586
    • Intercellular adhesion molecule-1-deficient mice are resistant against renal injury after induction of diabetes. Okada S, Shikata K, Matsuda M, Ogawa D, Usui H, Kido Y, Nagase R, Wada J, Shikata Y, Makino H, Diabetes 2003 52 2586 2593 10.2337/diabetes.52.10.2586 14514644 (Pubitemid 37210549)
    • (2003) Diabetes , vol.52 , Issue.10 , pp. 2586-2593
    • Okada, S.1    Shikata, K.2    Matsuda, M.3    Ogawa, D.4    Usui, H.5    Kido, Y.6    Nagase, R.7    Wada, J.8    Shikata, Y.9    Makino, H.10
  • 28
    • 0029924637 scopus 로고    scopus 로고
    • Neutralization of TGF-beta by anti-TGF-beta antibody attenuates kidney hypertrophy and the enhanced extracellular matrix gene expression in STZ-induced diabetic mice
    • 10.2337/diabetes.45.4.522 8603776
    • Neutralization of TGF-beta by anti-TGF-beta antibody attenuates kidney hypertrophy and the enhanced extracellular matrix gene expression in STZ-induced diabetic mice. Sharma K, Jin Y, Guo J, Ziyadeh FN, Diabetes 1996 45 522 530 10.2337/diabetes.45.4.522 8603776
    • (1996) Diabetes , vol.45 , pp. 522-530
    • Sharma, K.1    Jin, Y.2    Guo, J.3    Ziyadeh, F.N.4
  • 31
    • 0025789648 scopus 로고
    • Biochemical analysis of connexin43 intracellular transport, phosphorylation, and assembly into gap junctional plaques
    • Biochemical analysis of connexin43 intracellular transport, phosphorylation, and assembly into gap junctional plaques. Musil LS, Goodenough DA, J Cell Biol 1991 115 1357 1374 10.1083/jcb.115.5.1357 1659577 (Pubitemid 21909980)
    • (1991) Journal of Cell Biology , vol.115 , Issue.5 , pp. 1357-1374
    • Musil, L.S.1    Goodenough, D.A.2
  • 32
    • 0026025267 scopus 로고
    • Turnover and phosphorylation dynamics of connexin43 gap junction protein in cultured cardiac myocytes
    • 1846532
    • Turnover and phosphorylation dynamics of connexin43 gap junction protein in cultured cardiac myocytes. Laird DW, Puranam KL, Revel JP, Biochem J 1991 273 Pt 1 67 72 1846532
    • (1991) Biochem J , vol.273 , Issue.PART 1 , pp. 67-72
    • Laird, D.W.1    Puranam, K.L.2    Revel, J.P.3
  • 33
    • 0029176855 scopus 로고
    • Gap junction turnover, intracellular trafficking, and phosphorylation of connexin43 in brefeldin A-treated rat mammary tumor cells
    • 10.1083/jcb.131.5.1193 8522583
    • Gap junction turnover, intracellular trafficking, and phosphorylation of connexin43 in brefeldin A-treated rat mammary tumor cells. Laird DW, Castillo M, Kasprzak L, J Cell Biol 1995 131 1193 1203 10.1083/jcb.131.5.1193 8522583
    • (1995) J Cell Biol , vol.131 , pp. 1193-1203
    • Laird, D.W.1    Castillo, M.2    Kasprzak, L.3
  • 34
    • 0037560281 scopus 로고    scopus 로고
    • Intercellular signalling within vascular cells under high D-glucose involves free radical-triggered tyrosine kinase activation
    • DOI 10.1007/s00125-003-1091-y
    • Intercellular signalling within vascular cells under high D-glucose involves free radical-triggered tyrosine kinase activation. Schaeffer G, Levak-Frank S, Spitaler MM, Fleischhacker E, Esenabhalu VE, Wagner AH, Hecker M, Graier WF, Diabetologia 2003 46 773 783 10.1007/s00125-003-1091-y 12811469 (Pubitemid 36831405)
    • (2003) Diabetologia , vol.46 , Issue.6 , pp. 773-783
    • Schaeffer, G.1    Levak-Frank, S.2    Spitaler, M.M.3    Fleischhacker, E.4    Esenabhalu, V.E.5    Wagner, A.H.6    Hecker, M.7    Graier, W.F.8
  • 35
    • 57349165885 scopus 로고    scopus 로고
    • High glucose promotes retinal endothelial cell migration through activation of Src, PI3K/Akt1/eNOS, and ERKs
    • 10.1152/ajpcell.00322.2008 18945941
    • High glucose promotes retinal endothelial cell migration through activation of Src, PI3K/Akt1/eNOS, and ERKs. Huang Q, Sheibani N, Am J Physiol Cell Physiol 2008 295 1647 1657 10.1152/ajpcell.00322.2008 18945941
    • (2008) Am J Physiol Cell Physiol , vol.295 , pp. 31647-31657
    • Huang, Q.1    Sheibani, N.2
  • 36
    • 33645115754 scopus 로고    scopus 로고
    • C-Src: Bridging the gap between phosphorylation- and acidification- induced gap junction channel closure
    • 15998870
    • c-Src: bridging the gap between phosphorylation- and acidification- induced gap junction channel closure. Lau AF, Sci STKE 2005 2005 e33 15998870
    • (2005) Sci STKE , vol.2005
    • Lau, A.F.1
  • 38
    • 84857580186 scopus 로고    scopus 로고
    • HIF-1 and c-Src mediate increased glucose uptake induced by endothelin-1 and Connexin43 in astrocytes
    • 10.1371/journal.pone.0032448 22384254
    • HIF-1 and c-Src mediate increased glucose uptake induced by endothelin-1 and Connexin43 in astrocytes. Valle-Casuso JC, Gonzalez-Sanchez A, Medina JM, Tabernero A, PLoS One 2012 7 32448 10.1371/journal.pone.0032448 22384254
    • (2012) PLoS One , vol.7 , pp. 532448
    • Valle-Casuso, J.C.1    Gonzalez-Sanchez, A.2    Medina, J.M.3    Tabernero, A.4
  • 40
    • 0035911153 scopus 로고    scopus 로고
    • Activation of nuclear factor κB and bcl-x survival gene expression by nerve growth factor requires tyrosine phosphorylation of IκBα
    • DOI 10.1083/jcb.152.4.753
    • Activation of nuclear factor kappa B and bcl-x survival gene expression by nerve growth factor requires tyrosine phosphorylation of I kappa B alpha. Bui NT, Livolsi A, Peyron JF, Prehn JHM, J Cell Biol 2001 152 753 763 10.1083/jcb.152.4.753 11266466 (Pubitemid 34280160)
    • (2001) Journal of Cell Biology , vol.152 , Issue.4 , pp. 753-763
    • Bui, N.T.1    Livolsi, A.2    Peyron, J.-F.3    Prehn, J.H.M.4
  • 41
    • 34249799899 scopus 로고    scopus 로고
    • Genome-wide analysis of gene expression in T cells to identify targets of the NF-κB transcription factor c-Rel
    • Genome-wide analysis of gene expression in T cells to identify targets of the NF-kappa B transcription factor c-Rel. Bunting K, Rao S, Hardy K, Woltring D, Denyer GS, Wang J, Gerondakis S, Shannon MF, J Immunol 2007 178 7097 7109 17513759 (Pubitemid 46847436)
    • (2007) Journal of Immunology , vol.178 , Issue.11 , pp. 7097-7109
    • Bunting, K.1    Rao, S.2    Hardy, K.3    Woltring, D.4    Denyer, G.S.5    Wang, J.6    Gerondalds, S.7    Shannon, M.F.8
  • 42
    • 79959458818 scopus 로고    scopus 로고
    • Spontaneous lung dysfunction and fibrosis in mice lacking connexin 40 and endothelial cell connexin 43
    • 10.1016/j.ajpath.2011.02.045 21641379
    • Spontaneous lung dysfunction and fibrosis in mice lacking connexin 40 and endothelial cell connexin 43. Koval M, Billaud M, Straub AC, Johnstone SR, Zarbock A, Duling BR, Isakson BE, Am J Pathol 2011 178 2536 2546 10.1016/j.ajpath.2011.02.045 21641379
    • (2011) Am J Pathol , vol.178 , pp. 2536-2546
    • Koval, M.1    Billaud, M.2    Straub, A.C.3    Johnstone, S.R.4    Zarbock, A.5    Duling, B.R.6    Isakson, B.E.7
  • 44
    • 4544329815 scopus 로고    scopus 로고
    • Bimodal effect of advanced glycation end products on mesangial cell proliferation is mediated by neutral ceramidase regulation and endogenous sphingolipids
    • DOI 10.1074/jbc.M403273200
    • Bimodal effect of advanced glycation end products on mesangial cell proliferation is mediated by neutral ceramidase regulation and endogenous sphingolipids. Geoffroy K, Wiernsperger N, Lagarde M, El Bawab S, J Biol Chem 2004 279 34343 34352 10.1074/jbc.M403273200 15184394 (Pubitemid 39318059)
    • (2004) Journal of Biological Chemistry , vol.279 , Issue.33 , pp. 34343-34352
    • Geoffroy, K.1    Wiernsperger, N.2    Lagarde, M.3    El Bawab, S.4
  • 45
    • 78149410755 scopus 로고    scopus 로고
    • Berberine attenuates lipopolysaccharide-induced extracelluar matrix accumulation and inflammation in rat mesangial cells: Involvement of NF-kappa B signaling pathway
    • 10.1016/j.mce.2010.07.023 20674665
    • Berberine attenuates lipopolysaccharide-induced extracelluar matrix accumulation and inflammation in rat mesangial cells: Involvement of NF-kappa B signaling pathway. Jiang Q, Liu PQ, Wu XQ, Liu WH, Shen XY, Lan TA, Xu SW, Peng J, Xie X, Huang HQ, Mol Cell Endocrinol 2011 331 34 40 10.1016/j.mce.2010.07.023 20674665
    • (2011) Mol Cell Endocrinol , vol.331 , pp. 34-40
    • Jiang, Q.1    Liu, P.Q.2    Wu, X.Q.3    Liu, W.H.4    Shen, X.Y.5    Lan, T.A.6    Xu, S.W.7    Peng, J.8    Xie, X.9    Huang, H.Q.10
  • 46
    • 77953537219 scopus 로고    scopus 로고
    • Effects of berberine on matrix accumulation and NF-kappa B signal pathway in alloxan-induced diabetic mice with renal injury
    • 10.1016/j.ejphar.2010.04.033 20447389
    • Effects of berberine on matrix accumulation and NF-kappa B signal pathway in alloxan-induced diabetic mice with renal injury. Liu WH, Zhang XY, Liu PQ, Shen XY, Lan TA, Li WY, Jiang Q, Xie X, Huang HQ, Eur J Pharmacol 2010 638 150 155 10.1016/j.ejphar.2010.04.033 20447389
    • (2010) Eur J Pharmacol , vol.638 , pp. 150-155
    • Liu, W.H.1    Zhang, X.Y.2    Liu, P.Q.3    Shen, X.Y.4    Lan, T.A.5    Li, W.Y.6    Jiang, Q.7    Xie, X.8    Huang, H.Q.9
  • 47
    • 77956339397 scopus 로고    scopus 로고
    • Berberine ameliorates renal injury in diabetic C57BL/6 mice: Involvement of suppression of SphK-S1P signaling pathway
    • 10.1016/j.abb.2010.07.012 20646989
    • Berberine ameliorates renal injury in diabetic C57BL/6 mice: involvement of suppression of SphK-S1P signaling pathway. Lan T, Shen X, Liu P, Liu W, Xu S, Xie X, Jiang Q, Li W, Huang H, Arch Biochem Biophys 2010 502 112 120 10.1016/j.abb.2010.07.012 20646989
    • (2010) Arch Biochem Biophys , vol.502 , pp. 112-120
    • Lan, T.1    Shen, X.2    Liu, P.3    Liu, W.4    Xu, S.5    Xie, X.6    Jiang, Q.7    Li, W.8    Huang, H.9


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.