BMK1 is activated in glomeruli of diabetic rats and in mesangial cells by high glucose conditions

Kidney International

Volumn 65, Issue 5, 2004, Pages 1749-1760

  Suzaki, Yuki ^b   Yoshizumi, Masanori ^a   Kagami, Shoji ^b   Nishiyama, Akira ^b   Ozawa, Yuichi ^b   Kyaw, Moe ^b   Izawa, Yuki ^b   Kanematsu, Yasuhisa ^b   Tsuchiya, Koichiro ^b   Tamaki, Toshiaki ^b  

^a UNIVERSITY OF TOKUSHIMA   (Japan)

^b NONE

Author keywords

c Src; Diabetic nephropathy; Proliferation; Protein kinase C

Indexed keywords

1,4 DIAMINO 1,4 BIS(2 AMINOPHENYLTHIO) 2,3 DICYANOBUTADIENE; 2 (2 AMINO 3 METHOXYPHENYL)CHROMONE; 2 [1 (3 DIMETHYLAMINOPROPYL) 3 INDOLYL] 3 (3 INDOLYL)MALEIMIDE; GLUCOSE; HERBIMYCIN A; MITOGEN ACTIVATED PROTEIN KINASE; MITOGEN ACTIVATED PROTEIN KINASE 1; MITOGEN ACTIVATED PROTEIN KINASE P38;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; CELL PROLIFERATION; CONFERENCE PAPER; CONTROLLED STUDY; DIABETES MELLITUS; ENZYME ACTIVATION; ENZYME ACTIVITY; GLOMERULUS; MESANGIUM CELL; NON INSULIN DEPENDENT DIABETES MELLITUS; NONHUMAN; PRIORITY JOURNAL; RAT;

EID: 2342522648     PISSN: 00852538     EISSN: None     Source Type: Journal    
DOI: 10.1111/j.1523-1755.2004.00576.x     Document Type: Conference Paper

References (45)

1. JOSS N, PATERSON KR, DEIGHAN CJ, et al: Diabetic nephropathy: How effective is treatment in clinical practice? Q J Med 95:41-49, 2002
2. THE DIABETES CONTROL AND COMPLICATIONS TRIAL RESEARCH GROUP: The effect of intensive treatment of diabetes on the development and progression of long-term complications in insulin-dependent diabetes mellitus. N Engl J Med 329:977-986, 1993
3. UK PROSPECTIVE DIABETES STUDY (UKPDS) GROUP: Intensive blood-glucose control with sulphonylureas or insulin compared with conventional treatment and risk of complications in patients with type 2 diabetes (UKPDS 33). Lancet 352:837-853, 1998
4. PARK JY, HA SW, KING GL: The role of protein kinase C activation in the pathogenesis of diabetic vascular complications. Perit Dial Int 19:S222-S227, 1999
5. SHAH SV: Light emission by isolated rat glomeruli in response to phorbol myristate acetate. J Lab Clin Med 98:46-57, 1981
6. MIYANOSHITA A, TAKAHASHI T, ENDOU H: Inhibitory effect of cyclic AMP on phorbol ester-stimulated production of reactive oxygen metabolites in rat glomeruli. Biochem Biophys Res Commun 165:519-525, 1989
7. HA H, ENDOU H: Lipid peroxidation in isolated rat nephron segments. Am J Physiol 263:F201-F207, 1992
8. HA H, LEE HB: Reactive oxygen species as glucose signaling molecules in mesangial cells cultured under high glucose. Kidney Int 58 (Suppl 77):S19-S25, 2000
9. TOMLINSON DR: Mitogen-activated protein kinases as glucose transducers for diabetic complications. Diabetologia 42:1271-1281, 1999
10. ABE J, BERK BC: Reactive oxygen species as mediators of signal transduction in cardiovascular disease. Trends Cardiovasc Med 8:59-64, 1998
11. BERK BC: Redox signals that regulate the vascular response to injury. Thromb Haemost 82:810-817, 1999
12. WIDMANN C, GIBSON S, JARPE MB, JOHNSON GL: Mitogen-activated protein kinase: Conservation of a three-kinase module from yeast to human. Physiol Rev 79:143-180, 1999
13. ZHOU G, BAO ZQ, DIXON JE: Components of a new human protein kinase signal transduction pathway. J Biol Chem 270:12665-12669, 1995
14. LEE JD, ULEVITCH RJ, HAN J: Primary structure of BMK1: A new mammalian map kinase. Biochem Biophys Res Commun 213:715-724, 1995
15. KAGAMI S, URUSHIHARA M, KONDO S, et al: Effects of anti-alpha1 integrin subunit antibody on anti-Thy-1 glomerulonephritis. Lab Invest 82:1219-1227, 2002
16. KAGAMI S, URUSHIHARA M, KONDO S, et al: Requirement for tyrosine kinase-ERK1/2 signaling in alpha 1 beta 1 integrin-mediated collagen matrix remodeling by rat mesangial cells. Exp Cell Res 268:274-283, 2001
17. KAMAKURA S, MORIGUCHI T, NISHIDA E: Activation of the protein kinase ERK5/BMK1 by receptor tyrosine kinases. Identification and characterization of a signaling pathway to the nucleus. J Biol Chem 274:26563-26571, 1999
18. YOSHIZUMI M, ABE J, HAENDELER J, et al: Src and Cas mediate JNK activation but not ERK1/2 and p38 kinases by reactive oxygen species. J Biol Chem 275:11706-11712, 2000
19. COHEN MP, ZIYADEH FN, LAUTENSLAGER GT, et al: Glycated albumin stimulation of PKC-beta activity is linked to increased collagen IV in mesangial cells. Am J Physiol 276:F684-F690, 1999
20. TWENTYMAN PR, LUSCOMBE M: A study of some variables in a tetrazolium dye (MTT) based assay for cell growth and chemosensitivity. Br J Cancer 56:279-285, 1987
21. SUZAKI Y, YOSHIZUMI M, KAGAMI S, et al: Hydrogen peroxide stimulates c-Src-mediated big mitogen-activated protein kinase 1 (BMK1) and the MEF2C signaling pathway in PC12 cells: Potential role in cell survival following oxidative insults. J Biol Chem 277:9614-9621, 2002
22. OKADA M, TAKEMURA T, YANAGIDA H, YOSHIOKA K: Response of mesangial cells to low-density lipoprotein and angiotensin II in diabetic (OLETF) rats. Kidney Int 61:113-124, 2002
23. LI C, YANG CW, PARK CW, et al: Long-term treatment with ramipril attenuates renal osteopontin expression in diabetic rats. Kidney Int 63:454-463, 2003
24. ABE J, KUSUHARA M, ULEVITCH RJ, et al: Big mitogen-activated protein kinase 1 (BMK1) is a redox-sensitive kinase. J Biol Chem 271:16586-16590, 1996
25. YAN C, TAKAHASHI M, OKUDA M, et al: Fluid shear stress stimulates big mitogen-activated protein kinase 1 (BMK1) activity in endothelial cells. Dependence on tyrosine kinases and intracellular calcium. J Biol Chem 274:143-150, 1999
26. LIU W, SCHOENKERMAN A, LOWE WL, JR.: Activation of members of the mitogen-activated protein kinase family by glucose in endothelial cells. Am J Physiol Endocrinol Metab 279:E782-E790, 2000
27. CHAO TH, HAYASHI M, TAPPING RI, et al: MEKK3 directly regulates MEK5 activity as part of the big mitogen-activated protein kinase 1 (BMK1) signaling pathway. J Biol Chem 274:36035-36038, 1999
28. HANEDA M, KOYA D, KIKKAWA R: Cellular mechanisms in the development and progression of diabetic nephropathy: Activation of the DAG-PKC-ERK pathway. Am J Kidney Dis 38:S178-S181, 2001
29. ABE J, TAKAHASHI M, ISHIDA M, et al: c-Src is required for oxidative stress-mediated activation of big mitogen-activated protein kinase 1. J Biol Chem 272:20389-20394, 1997
30. SODHI CP, PHADKE SA, BATLLE D, SAHAI A: Hypoxia and high glucose cause exaggerated mesangial cell growth and collagen synthesis: Role of osteopontin. Am J Physiol Renal Physiol 280:F667-F674, 2001
31. HECQUET C, LEFEVRE G, VALTINK M, et al: cAMP inhibits the proliferation of retinal pigmented epithelial cells through the inhibition of ERK1/2 in a PKA-independent manner. Oncogene 21:6101-6112, 2002
32. YU C, WANG Z, DENT P, GRANT S: MEK1/2 inhibitors promote Ara-C-induced apoptosis but not loss of Deltapsi(m) in HL-60 cells. Biochem Biophys Res Commun 286:1011-1018, 2001
33. BOBROVSKAYA L, ODELL A, LEAL RB, DUNKLEY PR: Tyrosine hydroxylase phosphorylation in bovine adrenal chromaffin cells: The role of MAPKs after angiotensin II stimulation. J Neurochem 78:490-498, 2001
34. HANEDA M, ARAKI S, TOGAWA M, et al: Mitogen-activated protein kinase cascade is activated in glomeruli of diabetic rats and glomerular mesangial cells cultured under high glucose conditions. Diabetes 46:847-853, 1997
35. KANG SW, ADLER SG, LAPAGE J, NATARAJAN R: p38 MAPK and MAPK kinase 3/6 mRNA and activities are increased in early diabetic glomeruli. Kidney Int 60:543-552, 2001
36. FELIERS D, DURAISAMY S, FAULKNER JL, et al: Activation of renal signaling pathways in db/db mice with type 2 diabetes. Kidney Int 60:495-504, 2001
37. KATO Y, KRAVCHENKO VV, TAPPING RI, et al: BMK1/ERK5 regulates serum-induced early gene expression through transcription factor MEF2C. EMBO J 16:7054-7066, 1997
38. KATO Y, TAPPING RI, HUANG S, et al: Bmk1/Erk5 is required for cell proliferation induced by epidermal growth factor. Nature 395:713-716, 1998
39. LUO H, REIDY MA: Activation of big mitogen-activated protein kinase-1 regulates smooth muscle cell replication. Arterioscler Thromb Vasc Biol 22:394-399, 2002
40. KAWANO K, HIRASHIMA T, MORI S, et al: Spontaneous long-term hyperglycemic rat with diabetic complications. Otsuka Long-Evans Tokushima Fatty (OLETF) strain. Diabetes 41:1422-1428, 1992
41. CAVANAUGH JE, HAM J, HETMAN M, et al: Differential regulation of mitogen-activated protein kinases ERK1/2 and ERK5 by neurotrophins, neuronal activity, and cAMP in neurons. J Neurosci 21:434-443, 2001
42. DIAZ-MECO MT, MOSCAT J: MEK5, a new target of the atypical protein kinase C isoforms in mitogenic signaling. Mol Cell Biol 21:1218-1227, 2001
43. DONG F, GUTKIND JS, LARNER AC: Granulocyte colony-stimulating factor induces erk5 activation, which is differentially regulated by protein-tyrosine kinases and protein kinase c regulation of cell proliferation and survival. J Biol Chem 276:10811-10816, 2001
44. SRIVASTAVA AK: High glucose-induced activation of protein kinase signaling pathways in vascular smooth muscle cells: A potential role in the pathogenesis of vascular dysfunction in diabetes (review). Int J Mol Med 9:85-89, 2002
45. DINEV D, JORDAN BW, NEUFELD B, et al: Extracellular signal regulated kinase 5 (ERK5) is required for the differentiation of muscle cells. EMBO Rep 2:829-834, 2001