High glucose-induced hypertrophy of mesangial cells is reversed by connexin43 overexpression via PTEN/Akt/mTOR signaling

Nephrology Dialysis Transplantation

Volumn 27, Issue 1, 2012, Pages 90-100

  Liu, Lin ^a   Hu, Xiao ^a   Cai, Guang Yan ^a   Lv, Yang ^a   Zhuo, Li ^a   Gao, Jian Jun ^a   Cui, Shao Yuan ^a   Feng, Zhe ^a   Fu, Bo ^a   Chen, Xiang Mei ^a  

^a CHINESE PLA GENERAL HOSPITAL   (China)

Author keywords

connexin43; high glucose; hypertrophy; mTOR; PTEN

Indexed keywords

CONNEXIN 43; GLUCOSE; MAMMALIAN TARGET OF RAPAMYCIN; MESSENGER RNA; PHOSPHATIDYLINOSITOL 3,4,5 TRISPHOSPHATE 3 PHOSPHATASE; PROTEIN KINASE B;

ANIMAL CELL; ARTICLE; CELL COUNT; CELL CYCLE ARREST; CELL CYCLE G0 PHASE; CELL CYCLE G1 PHASE; CELL CYCLE REGULATION; CELL CYCLE S PHASE; CELL PROLIFERATION; CELL SIZE; CONTROLLED STUDY; ENZYME ACTIVATION; ENZYME INHIBITION; ENZYME PHOSPHORYLATION; FLOW CYTOMETRY; GENE EXPRESSION REGULATION; HYPERGLYCEMIA; IMMUNOFLUORESCENCE; INTRACELLULAR SIGNALING; KIDNEY HYPERTROPHY; MALE; MESANGIUM CELL; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN FUNCTION; PROTEIN SYNTHESIS; RAT;

ANIMALS; BLOTTING, WESTERN; CELL PROLIFERATION; CELLS, CULTURED; CONNEXIN 43; FLOW CYTOMETRY; FLUORESCENT ANTIBODY TECHNIQUE; GENE EXPRESSION REGULATION; GLOMERULAR MESANGIUM; GLUCOSE; HYPERGLYCEMIA; HYPERTROPHY; MALE; MESANGIAL CELLS; PROTO-ONCOGENE PROTEINS C-AKT; PTEN PHOSPHOHYDROLASE; RATS; RATS, WISTAR; REAL-TIME POLYMERASE CHAIN REACTION; RNA, MESSENGER; RNA, SMALL INTERFERING; SIGNAL TRANSDUCTION; TOR SERINE-THREONINE KINASES;

EID: 84863011181     PISSN: 09310509     EISSN: 14602385     Source Type: Journal    
DOI: 10.1093/ndt/gfr265     Document Type: Article

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