Activation of Src mediates PDGF-induced Smad1 phosphorylation and contributes to the progression of glomerulosclerosis in glomerulonephritis

PLoS ONE

Volumn 6, Issue 3, 2011, Pages

  Mima, Akira ^a,b   Abe, Hideharu ^a   Nagai, Kojiro ^a   Arai, Hidenori ^b   Matsubara, Takeshi ^b   Araki, Makoto ^b   Torikoshi, Kazuo ^b   Tominaga, Tatsuya ^a   Iehara, Noriyuki ^b   Fukatsu, Atsushi ^b   Kita, Toru ^b   Doi, Toshio ^a  

^a UNIVERSITY OF TOKUSHIMA   (Japan)

^b KYOTO UNIVERSITY GRADUATE SCHOOL OF MEDICINE   (Japan)

Author keywords

[No Author keywords available]

Indexed keywords

4 AMINO 7 TERT BUTYL 5 (4 CHLOROPHENYL)PYRAZOLO[3,4 D]PYRIMIDINE; ALPHA SMOOTH MUSCLE ACTIN; COLLAGEN TYPE 4; PHOSPHOPROTEIN KINASE P60; PHOSPO SMAD1 PROTEIN; PLATELET DERIVED GROWTH FACTOR; PROTEIN KINASE P60; SMAD1 PROTEIN; SMALL INTERFERING RNA; THY 1 ANTIGEN; TRANSFORMING GROWTH FACTOR BETA; UNCLASSIFIED DRUG;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; COLLAGEN SYNTHESIS; CONTROLLED STUDY; DISEASE COURSE; ENZYME ACTIVATION; GLOMERULOSCLEROSIS; IMMUNOHISTOCHEMISTRY; IN VITRO STUDY; MALE; MESANGIUM CELL; NONHUMAN; PROLIFERATIVE GLOMERULONEPHRITIS; PROTEIN EXPRESSION; PROTEIN FUNCTION; PROTEIN PHOSPHORYLATION; PROTEIN SYNTHESIS; RAT; SIGNAL TRANSDUCTION; ANIMAL; C57BL MOUSE; GLOMERULONEPHRITIS; METABOLISM; MOUSE; PATHOLOGY; PHOSPHORYLATION; WESTERN BLOTTING;

RATTUS;

ANIMALS; BLOTTING, WESTERN; DISEASE PROGRESSION; GLOMERULONEPHRITIS; IMMUNOHISTOCHEMISTRY; MICE; MICE, INBRED C57BL; PHOSPHORYLATION; PLATELET-DERIVED GROWTH FACTOR; PROTO-ONCOGENE PROTEINS PP60(C-SRC); RNA, SMALL INTERFERING; SIGNAL TRANSDUCTION; SMAD1 PROTEIN;

EID: 79952903211     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0017929     Document Type: Article

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