Structural plasticity of the cellular prion protein and implications in health and disease

Proceedings of the National Academy of Sciences of the United States of America

Volumn 110, Issue 21, 2013, Pages 8549-8554

  Christen, Barbara ^a   Damberger, Fred F ^a   Pérez, Daniel R ^a   Hornemann, Simone ^a,c   Wüthrich, Kurt ^a,b  

^a ETH ZURICH   (Switzerland)

^b SCRIPPS RESEARCH INSTITUTE   (United States)

^c UNIVERSITY HOSPITAL ZURICH   (Switzerland)

Author keywords

Conformational equilibrium; NMR line shape analysis; Prion protein stability; Protein dynamics

Indexed keywords

PRION PROTEIN;

AMINO ACID SEQUENCE; ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; BRAIN TISSUE; CONFORMATIONAL TRANSITION; IN VITRO STUDY; MOUSE; NONHUMAN; NUCLEAR MAGNETIC RESONANCE SPECTROSCOPY; PRION DISEASE; PRIORITY JOURNAL; PROTEIN POLYMORPHISM; PROTEIN STRUCTURE; SCRAPIE; TRANSGENIC MOUSE;

CONFORMATIONAL EQUILIBRIUM; NMR LINE SHAPE ANALYSIS; PRION PROTEIN STABILITY; PROTEIN DYNAMICS;

ANIMALS; BRAIN; BRAIN CHEMISTRY; DEER; HORSES; HUMANS; MICE; MICE, TRANSGENIC; PRION DISEASES; PROTEIN STRUCTURE, SECONDARY; PRPC PROTEINS;

EID: 84878159247     PISSN: 00278424     EISSN: 10916490     Source Type: Journal    
DOI: 10.1073/pnas.1306178110     Document Type: Article

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