Structural facets of disease-linked human prion protein mutants: A molecular dynamic study

Proteins: Structure, Function and Bioinformatics

Volumn 78, Issue 16, 2010, Pages 3270-3280

  Rossetti, Giulia ^a,b,c,d   Giachin, Gabriele ^a   Legname, Giuseppe ^a,c,e   Carloni, Paolo ^a,b,c,d  

^a SISSA   (Italy)

^b DEMOCRITOS NATIONAL SIMULATION CENTER   (Italy)

^c ISTITUTO ITALIANO DI TECNOLOGIA   (Italy)

^d RWTH AACHEN UNIVERSITY   (Germany)

^e SINCROTRONE TRIESTE   (Italy)

Author keywords

Aggregation; Conformation; Conversion; Disease; Dynamic; Mutant; Prion; Protocol

Indexed keywords

PRION PROTEIN;

ACCURACY; AQUEOUS SOLUTION; ARTICLE; CONFORMATIONAL TRANSITION; CREUTZFELDT JAKOB DISEASE; FATAL FAMILIAL INSOMNIA; GENE MUTATION; GENETIC POLYMORPHISM; GERSTMANN STRAUSSLER SCHEINKER SYNDROME; MOLECULAR DYNAMICS; NUCLEAR MAGNETIC RESONANCE; PRIORITY JOURNAL; PROTEIN DOMAIN; PROTEIN STRUCTURE; PROTEIN VARIANT; WILD TYPE;

AMINO ACID SEQUENCE; CLUSTER ANALYSIS; HUMANS; MAGNETIC RESONANCE SPECTROSCOPY; MOLECULAR DYNAMICS SIMULATION; MOLECULAR SEQUENCE DATA; MUTANT PROTEINS; PRION DISEASES; PRIONS; PROTEIN STRUCTURE, SECONDARY;

EID: 78349283012     PISSN: 08873585     EISSN: 10970134     Source Type: Journal    
DOI: 10.1002/prot.22834     Document Type: Article

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