Insight into the PrPc → PrPSc conversion from the structures of antibody-bound ovine prion scrapie-susceptibility variants

Proceedings of the National Academy of Sciences of the United States of America

Volumn 101, Issue 28, 2004, Pages 10254-10259

  Eghiaian, Frédéric ^a   Grosclaude, Jeanne ^b   Lesceu, Stéphanie ^c   Debey, Pascale ^d   Doublet, Bénédicte ^b   Tréguer, Eric ^b   Rezaei, Human ^b   Knossow, Marcel ^a  

^a CNRS   (France)

^b INRA Institut National de la Recherche Agronomique   (France)

^c Institut POURQUIER   (France)

^d MUSÉUM NATIONAL D'HISTOIRE NATURELLE   (France)

Author keywords

[No Author keywords available]

Indexed keywords

PRION PROTEIN; EPITOPE;

ALPHA HELIX; AMINO TERMINAL SEQUENCE; ANIMAL TISSUE; ARTICLE; COMPLEX FORMATION; CONFORMATIONAL TRANSITION; CRYSTAL STRUCTURE; CRYSTALLIZATION; GENE; GENE CONVERSION; GENE MUTATION; GENETIC SUSCEPTIBILITY; NONHUMAN; PRION DISEASE; PRIORITY JOURNAL; PROTEIN DOMAIN; PROTEIN SECONDARY STRUCTURE; PROTEIN STABILITY; PRP GENE; SCRAPIE; ANIMAL; ANTIBODY SPECIFICITY; ANTIGEN ANTIBODY REACTION; CHEMISTRY; CRYSTALLOGRAPHY; GENETICS; IMMUNOLOGY; MOUSE; MUTATION; PROTEIN TERTIARY STRUCTURE; SHEEP;

ANIMALIA; OVIS;

ANIMALS; ANTIBODY SPECIFICITY; ANTIGEN-ANTIBODY REACTIONS; CRYSTALLOGRAPHY; EPITOPES; MICE; MUTATION; PROTEIN STRUCTURE, SECONDARY; PROTEIN STRUCTURE, TERTIARY; PRPC PROTEINS; PRPSC PROTEINS; SCRAPIE; SHEEP;

EID: 3142683624     PISSN: 00278424     EISSN: None     Source Type: Journal    
DOI: 10.1073/pnas.0400014101     Document Type: Article

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