A sequential one-pot protocol for the synthesis of dihydrobenzo[6,7]indolo- [3′,4′:3,4,5]azepino[2,1- a ]isoquinolines using a gold-silver combined catalyst 1

Synthesis (Germany)

Volumn 45, Issue 11, 2013, Pages 1553-1563

  Saifuddin, Mohammad ^a   Samala, Srinivas ^a   Krishna, Deevi G Venkata ^a   Kundu, Bijoy ^a,b  

^a CENTRAL DRUG RESEARCH INSTITUTE   (India)

^b ACADEMY OF SCIENTIFIC AND INNOVATIVE RESEARCH ACSIR   (India)

Author keywords

alkyne; annulation; indole; Lewis acid; polyheterocycles; regioselective

Indexed keywords

ALKYNE; ANNULATION; INDOLE; LEWIS ACID; POLYHETEROCYCLES; REGIO-SELECTIVE;

CYCLIZATION; GOLD; HYDROCARBONS; POLYCYCLIC AROMATIC HYDROCARBONS;

CATALYSTS;

13 FLUORO 5 METHYL 9 PHENYL 14B,16 DIHYDROBENZO[6,7]INDOLO[3',4':3,4,5]AZEPINO[2,1 A]ISOQUINOLINE; 13 FLUORO 9 (PARA TOLYL) 14B,16 DIHYDROBENZO[6,7]INDOLO[3',4':3,4,5]AZEPINO[2,1 A]ISOQUINOLINE; 13 FLUORO 9 (PARA TOLYL) 14B,16 DIHYDROINDOLO[3',4':3,4,5]PYRIDO[2',3':6,7]AZEPINO[2,1 A]ISOQUINOLINE; 13 FLUORO 9 PHENYL 14B,16 DIHYDROBENZO[6,7]INDOLO[3',4':3,4,5]AZEPINO[2,1 A]ISOQUINOLINE; 13 METHOXY 9 PHENYL 14B,16 DIHYDROBENZO[6,7]INDOLO[3',4':3,4,5]AZEPINO[2,1 A]ISOQUINOLINE; 5 METHYL 9 (PARA TOLYL) 14B,16 DIHYDROBENZO[6,7]INDOLO[3',4':3,4,5]AZEPINO[2,1 A]ISOQUINOLINE; 5 METHYL 9 PHENYL 14B,16 DIHYDROBENZO[6,7]INDOLO[3',4':3,4,5]AZEPINO[2,1 A]ISOQUINOLINE; 9 (2 NITROPHENYL) 14B,16 DIHYDROBENZO[6,7]INDOLO[3',4':3,4,5]AZEPINO[2,1 A]ISOQUINOLINE; 9 (4 METHOXYPHENYL) 14B,16 DIHYDROBENZO[6,7]INDOLO[3',4':3,4,5]AZEPINO[2,1 A]ISOQUINOLINE; 9 (4 METHOXYPHENYL) 5 METHYL 14B,16 DIHYDROBENZO[6,7]INDOLO[3',4':3,4,5]AZEPINO[2,1 A]ISOQUINOLINE; 9 (CYCLOHEX 1 EN 1 YL) 13 FLUORO 14B,16 DIHYDROBENZO[6,7]INDOLO[3',4':3,4,5]AZEPINO[2,1 A]ISOQUINOLINE; 9 (CYCLOHEX 1 EN 1 YL) 13 FLUORO 14B,16 DIHYDROINDOLO[3',4':3,4,5]PYRIDO[2',3':6,7]AZEPINO[2,1 A]ISOQUINOLINE; 9 (CYCLOHEX 1 EN 1 YL) 13 FLUORO 5 METHYL 14B,16 DIHYDROBENZO[6,7]INDOLO[3',4':3,4,5]AZEPINO[2,1 A]ISOQUINOLINE; 9 (CYCLOHEX 1 EN 1 YL) 13 METHOXY 14B,16 DIHYDROBENZO[6,7]INDOLO[3',4':3,4,5]AZEPINO[2,1 A]ISOQUINOLINE; 9 (CYCLOHEX 1 EN 1 YL) 13 METHOXY 14B,16 DIHYDROINDOLO[3',4':3,4,5]PYRIDO[2',3':6,7]AZEPINO[2,1 A]ISOQUINOLINE; 9 (CYCLOHEX 1 EN 1 YL) 13 METHOXY 5 METHYL 14B,16 DIHYDROBENZO[6,7]INDOLO[3',4':3,4,5]AZEPINO[2,1 A]ISOQUINOLINE; 9 (CYCLOHEX 1 EN 1 YL) 14B,16 DIHYDROBENZO[6,7]INDOLO[3',4':3,4,5]AZEPINO[2,1 A]ISOQUINOLINE; 9 (CYCLOHEX 1 EN 1 YL) 5 METHYL 14B,16 DIHYDROBENZO[6,7]INDOLO[3',4':3,4,5]AZEPINO[2,1 A]ISOQUINOLINE; 9 (PARA TOLYL) 14B,16 DIHYDROBENZO[6,7]INDOLO[3',4':3,4,5]AZEPINO[2,1 A]ISOQUINOLINE; 9 [4 (TERT BUTYL)PHENYL] 13 FLUORO 14B,16 DIHYDROBENZO[6,7]INDOLO[3',4':3,4,5]AZEPINO[2,1 A]ISOQUINOLINE; 9 [4 (TERT BUTYL)PHENYL] 13 FLUORO 5 METHYL 14B,16 DIHYDROBENZO[6,7]INDOLO[3',4':3,4,5]AZEPINO[2,1 A]ISOQUINOLINE; 9 [4 (TERT BUTYL)PHENYL] 13 METHOXY 14B,16 DIHYDROINDOLO[3',4':3,4,5]PYRIDO[2',3':6,7]AZEPINO[2,1 A]ISOQUINOLINE; 9 [4 (TERT BUTYL)PHENYL] 14B,16 DIHYDROBENZO[6,7]INDOLO[3',4':3,4,5]AZEPINO[2,1 A]ISOQUINOLINE; 9 [4 (TERT BUTYL)PHENYL] 5 METHYL 14B,16 DIHYDROBENZO[6,7]INDOLO[3',4':3,4,5]AZEPINO[2,1 A]ISOQUINOLINE; 9 PHENYL 14B,16 DIHYDROBENZO[6,7]INDOLO[3',4':3,4,5]AZEPINO[2,1 A]ISOQUINOLINE; 9 PHENYL 14B,16 DIHYDROINDOLO[3',4':3,4,5]PYRIDO[2',3':6,7]AZEPINO[2,1 A]ISOQUINOLINE; GOLD; QUINOLINE DERIVATIVE; SILVER; UNCLASSIFIED DRUG;

ARTICLE; CATALYST; CHEMICAL STRUCTURE; COLUMN CHROMATOGRAPHY; CYCLIZATION; ELECTROPHILICITY; HETERONUCLEAR MULTIPLE BOND CORRELATION; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; MELTING POINT; NUCLEAR OVERHAUSER EFFECT; ONE POT SYNTHESIS; ROOM TEMPERATURE; THIN LAYER CHROMATOGRAPHY;

EID: 84878134459     PISSN: 00397881     EISSN: 1437210X     Source Type: Journal    
DOI: 10.1055/s-0033-1338424     Document Type: Article

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