-
1
-
-
0032945558
-
The pharmacokinetic modelling of GI198745 (dutasteride), a compound with parallel linear and nonlinear elimination
-
Gisleskog PO, Hermann D, Hammarlund-Udenaes M, Karlsson MO. The pharmacokinetic modelling of GI198745 (dutasteride), a compound with parallel linear and nonlinear elimination. Br J Clin Pharmacol. 1999;47:53-58.
-
(1999)
Br J Clin Pharmacol
, vol.47
, pp. 53-58
-
-
Gisleskog, P.O.1
Hermann, D.2
Hammarlund-Udenaes, M.3
Karlsson, M.O.4
-
3
-
-
84857107913
-
-
US Food Drug Administration. Center for Drug Evaluation and Research. Application Number 21-319, Available from, Accessed March 4
-
US Food Drug Administration. Center for Drug Evaluation and Research. Application Number 21-319. Clinical pharmacology and biopharmaceutics review. Available from: http://www.accessdata.fda.gov/drugsatfda_docs/nda/2001/21319_Duagen_biopharmr_P1.pdf. Accessed March 4, 2013.
-
(2013)
Clinical Pharmacology and Biopharmaceutics Review
-
-
-
4
-
-
84878032497
-
-
Avodart® (product monograph). Middlesex, UK: GlaxoSmithKline, Available from, Accessed March 4
-
Avodart® (product monograph). Middlesex, UK: GlaxoSmithKline. Available from: http://www.gsk.ca/english/docs-pdf/productmonographs/Avodart.pdf. Accessed March 4, 2013.
-
(2013)
-
-
-
5
-
-
0035158246
-
Crosslinking studies in gelatin capsules treated with formaldehyde and in capsules exposed to elevated temperature and humidity
-
Ofner CM 3rd, Zhang YE, Jobeck VC, Bowman BJ. Crosslinking studies in gelatin capsules treated with formaldehyde and in capsules exposed to elevated temperature and humidity. J Pharm Sci. 2001;90: 79-88.
-
(2001)
J Pharm Sci
, vol.90
, pp. 79-88
-
-
Ofner, C.M.1
Zhang, Y.E.2
Jobeck, V.C.3
Bowman, B.J.4
-
6
-
-
84868590237
-
Improved supersaturation and oral absorption of dutasteride by amorphous solid dispersions
-
Beak IH, Kim MS. Improved supersaturation and oral absorption of dutasteride by amorphous solid dispersions. Chem Pharm Bull. 2012;60: 1468-1473.
-
(2012)
Chem Pharm Bull
, vol.60
, pp. 1468-1473
-
-
Beak, I.H.1
Kim, M.S.2
-
7
-
-
84878258812
-
Quality by design: Screening of critical variables and formulation optimization of Eudragit E nanoparticles containing dutasteride
-
February 28, Epub ahead of print
-
Park SJ, Choo GH, Hwang SJ, Kim MS. Quality by design: screening of critical variables and formulation optimization of Eudragit E nanoparticles containing dutasteride. Arch Pharm Res. February 28, 2013. [Epub ahead of print.]
-
(2013)
Arch Pharm Res
-
-
Park, S.J.1
Choo, G.H.2
Hwang, S.J.3
Kim, M.S.4
-
8
-
-
84877765534
-
Formulation and in vivo evaluation of a self-microemulsifying drug delivery system of dutasteride
-
Choo GH, Park SJ, Hwang SJ, Kim MS. Formulation and in vivo evaluation of a self-microemulsifying drug delivery system of dutasteride. Drug Res (Stuttg). 2013;63:203-209.
-
(2013)
Drug Res (Stuttg)
, vol.63
, pp. 203-209
-
-
Choo, G.H.1
Park, S.J.2
Hwang, S.J.3
Kim, M.S.4
-
9
-
-
84878023073
-
Soluplus-coated colloidal silica nanomatrix system for enhanced supersaturation and oral absorption of poorly water-soluble drugs
-
January 22, Epub ahead of print
-
Kim MS. Soluplus-coated colloidal silica nanomatrix system for enhanced supersaturation and oral absorption of poorly water-soluble drugs. Artif Cells Nanomed Biotechnol. January 22, 2013. [Epub ahead of print.]
-
(2013)
Artif Cells Nanomed Biotechnol
-
-
Kim, M.S.1
-
10
-
-
80053561797
-
Bioavailability and pharmacokinetics of sorafenib suspension, nanoparticles and nanomatrix for oral administration to rat
-
Wang XQ, Fan JM, Liu YO, et al. Bioavailability and pharmacokinetics of sorafenib suspension, nanoparticles and nanomatrix for oral administration to rat. Int J Pharm. 2011;419:339-346.
-
(2011)
Int J Pharm
, vol.419
, pp. 339-346
-
-
Wang, X.Q.1
Fan, J.M.2
Liu, Y.O.3
-
11
-
-
84859734219
-
Modification of physicochemical characteristics of active pharmaceutical ingredients and application of supersaturatable dosage forms for improving bioavailability of poorly absorbed drugs
-
Kawakami K. Modification of physicochemical characteristics of active pharmaceutical ingredients and application of supersaturatable dosage forms for improving bioavailability of poorly absorbed drugs. Adv Drug Deliv Rev. 2012;64:480-495.
-
(2012)
Adv Drug Deliv Rev
, vol.64
, pp. 480-495
-
-
Kawakami, K.1
-
12
-
-
82255162693
-
Supersaturation-nucleation behavior of poorly soluble drugs and its impact on the oral absorption of drugs in thermodynamically high-energy forms
-
Ozaki S, Minamisono T, Yamashita T, Kato T, Kushida I. Supersaturation-nucleation behavior of poorly soluble drugs and its impact on the oral absorption of drugs in thermodynamically high-energy forms. J Pharm Sci. 2012;101:214-222.
-
(2012)
J Pharm Sci
, vol.101
, pp. 214-222
-
-
Ozaki, S.1
Minamisono, T.2
Yamashita, T.3
Kato, T.4
Kushida, I.5
-
13
-
-
84866732706
-
Amorphous solid dispersion enhances permeation of poorly soluble ABT-102: True supersaturation vs apparent solubility enhancement
-
Frank KJ, Rosenblatt KM, Westedt U, et al. Amorphous solid dispersion enhances permeation of poorly soluble ABT-102: true supersaturation vs apparent solubility enhancement. Int J Pharm. 2012;437: 288-293.
-
(2012)
Int J Pharm
, vol.437
, pp. 288-293
-
-
Frank, K.J.1
Rosenblatt, K.M.2
Westedt, U.3
-
14
-
-
84870356219
-
The amorphous solid dispersion of the poorly soluble ABT-102 forms nano/microparticulate structures in aqueous medium: Impact on solubility
-
Frank KJ, Westedt U, Rosenblatt KM, et al. The amorphous solid dispersion of the poorly soluble ABT-102 forms nano/microparticulate structures in aqueous medium: impact on solubility. Int J Nanomedicine. 2012;7:5757-5768.
-
(2012)
Int J Nanomedicine
, vol.7
, pp. 5757-5768
-
-
Frank, K.J.1
Westedt, U.2
Rosenblatt, K.M.3
-
15
-
-
84874906594
-
Supersaturatable formulations for the enhanced oral absorption of sirolimus
-
Kim MS, Kim JS, Cho WK, et al. Supersaturatable formulations for the enhanced oral absorption of sirolimus. Int J Pharm. 2013;445: 108-116.
-
(2013)
Int J Pharm
, vol.445
, pp. 108-116
-
-
Kim, M.S.1
Kim, J.S.2
Cho, W.K.3
-
16
-
-
38049112810
-
Effect of stabilizer on the maximum degree and extent of supersaturation and oral absorption of tacrolimus made by ultra-rapid freezing
-
Overhoff KA, McConville JT, Yang W, et al. Effect of stabilizer on the maximum degree and extent of supersaturation and oral absorption of tacrolimus made by ultra-rapid freezing. Pharm Res. 2008;25: 167-175.
-
(2008)
Pharm Res
, vol.25
, pp. 167-175
-
-
Overhoff, K.A.1
McConville, J.T.2
Yang, W.3
-
17
-
-
34547882770
-
Use of a screening method to determine excipients which optimize the extent and stability of supersaturated drug solutions and application of this system to solid formulation design
-
Vandecruys R, Peeters J, Verreck G, Brewster ME. Use of a screening method to determine excipients which optimize the extent and stability of supersaturated drug solutions and application of this system to solid formulation design. Int J Pharm. 2007;342:168-175.
-
(2007)
Int J Pharm
, vol.342
, pp. 168-175
-
-
Vandecruys, R.1
Peeters, J.2
Verreck, G.3
Brewster, M.E.4
-
18
-
-
84869098143
-
Characterization of supersaturatable formulations for improved absorption of poorly soluble drugs
-
Gao P, Shi Y. Characterization of supersaturatable formulations for improved absorption of poorly soluble drugs. AAPS J. 2012;14: 703-713.
-
(2012)
AAPS J
, vol.14
, pp. 703-713
-
-
Gao, P.1
Shi, Y.2
-
19
-
-
84874790365
-
Improvement of photostability and dissolution profile of isradipine using inclusion complex
-
Park JB, Lee GH, Kang JW, et al. Improvement of photostability and dissolution profile of isradipine using inclusion complex. J Pharm Investig. 2013;43:55-61.
-
(2013)
J Pharm Investig
, vol.43
, pp. 55-61
-
-
Park, J.B.1
Lee, G.H.2
Kang, J.W.3
-
20
-
-
1942434694
-
Self-association of cyclodextrins and cyclodextrin complexes
-
Loftsson T, Másson M, Brewster ME. Self-association of cyclodextrins and cyclodextrin complexes. J Pharm Sci. 2004;93:1091-1099.
-
(2004)
J Pharm Sci
, vol.93
, pp. 1091-1099
-
-
Loftsson, T.1
Másson, M.2
Brewster, M.E.3
-
21
-
-
1642419522
-
Preparation of solid drug/cyclodextrin complexes of acidic and basic drugs
-
Loftsson T, Sigurdsson H, Masson M, Schipper N. Preparation of solid drug/cyclodextrin complexes of acidic and basic drugs. Pharmazie. 2004;59:25-29.
-
(2004)
Pharmazie
, vol.59
, pp. 25-29
-
-
Loftsson, T.1
Sigurdsson, H.2
Masson, M.3
Schipper, N.4
-
22
-
-
0036689443
-
Stable supersaturated aqueous solutions of silatecan 7-t-butyldimethylsilyl-10-hydroxycamptothecin via chemical conversion in the presence of a chemically modified beta-cyclodextrin
-
Xiang TX, Anderson BD. Stable supersaturated aqueous solutions of silatecan 7-t-butyldimethylsilyl-10-hydroxycamptothecin via chemical conversion in the presence of a chemically modified beta-cyclodextrin. Pharm Res. 2002;19:1215-1222.
-
(2002)
Pharm Res
, vol.19
, pp. 1215-1222
-
-
Xiang, T.X.1
Anderson, B.D.2
-
23
-
-
44349083587
-
Comparative interaction of 2-hydroxypropyl-beta-cyclodextrin and sulfobutylether-beta-cyclodextrin with itraconazole: Phase-solubility behavior and stabilization of supersaturated drug solutions
-
Brewster ME, Vandecruys R, Peeters J, et al. Comparative interaction of 2-hydroxypropyl-beta-cyclodextrin and sulfobutylether-beta-cyclodextrin with itraconazole: phase-solubility behavior and stabilization of supersaturated drug solutions. Eur J Pharm Sci. 2008;34:94-103.
-
(2008)
Eur J Pharm Sci
, vol.34
, pp. 94-103
-
-
Brewster, M.E.1
Vandecruys, R.2
Peeters, J.3
-
24
-
-
84870357419
-
Enhancement of the dissolution rate and bioavailability of fenofibrate by a melt-adsorption method using supercritical carbon dioxide
-
Cha KH, Cho KJ, Kim MS, et al. Enhancement of the dissolution rate and bioavailability of fenofibrate by a melt-adsorption method using supercritical carbon dioxide. Int J Nanomedicine. 2012;7:5565-5575.
-
(2012)
Int J Nanomedicine
, vol.7
, pp. 5565-5575
-
-
Cha, K.H.1
Cho, K.J.2
Kim, M.S.3
-
25
-
-
44749087764
-
Physicochemical properties and oral bioavailability of amorphous atorvastatin hemi-calcium using spraydrying and SAS process
-
Kim JS, Kim MS, Park HJ, et al. Physicochemical properties and oral bioavailability of amorphous atorvastatin hemi-calcium using spraydrying and SAS process. Int J Pharm. 2008;359:211-219.
-
(2008)
Int J Pharm
, vol.359
, pp. 211-219
-
-
Kim, J.S.1
Kim, M.S.2
Park, H.J.3
-
26
-
-
84868233981
-
Application of mixtures of polymeric carriers for dissolution enhancement of oxeglitazar using hot-melt extrusion
-
Kalivoda A, Fischbach M, Kleinebudde P. Application of mixtures of polymeric carriers for dissolution enhancement of oxeglitazar using hot-melt extrusion. Int J Pharm. 2012;439:145-156.
-
(2012)
Int J Pharm
, vol.439
, pp. 145-156
-
-
Kalivoda, A.1
Fischbach, M.2
Kleinebudde, P.3
-
27
-
-
43249110027
-
Preparation, characterization and in vivo evaluation of amorphous atorvastatin calcium nanoparticles using supercritical antisolvent (SAS) process
-
Kim MS, Jin SJ, Kim JS, et al. Preparation, characterization and in vivo evaluation of amorphous atorvastatin calcium nanoparticles using supercritical antisolvent (SAS) process. Eur J Pharm Biopharm. 2008;69:454-465.
-
(2008)
Eur J Pharm Biopharm
, vol.69
, pp. 454-465
-
-
Kim, M.S.1
Jin, S.J.2
Kim, J.S.3
-
28
-
-
84862631967
-
Enhanced bioavailability of sirolimus via preparation of solid dispersion nanoparticles using a supercritical antisolvent process
-
Kim MS, Kim JS, Park HJ, et al. Enhanced bioavailability of sirolimus via preparation of solid dispersion nanoparticles using a supercritical antisolvent process. Int J Nanomedicine. 2011;6:2997-3009.
-
(2011)
Int J Nanomedicine
, vol.6
, pp. 2997-3009
-
-
Kim, M.S.1
Kim, J.S.2
Park, H.J.3
-
29
-
-
84859474061
-
Effect of solvent type on the nanoparticle formation of atorvastatin calcium by the supercritical antisolvent process
-
Kim MS, Song HS, Park HJ, Hwang SJ. Effect of solvent type on the nanoparticle formation of atorvastatin calcium by the supercritical antisolvent process. Chem Pharm Bull. 2012;60:543-547.
-
(2012)
Chem Pharm Bull
, vol.60
, pp. 543-547
-
-
Kim, M.S.1
Song, H.S.2
Park, H.J.3
Hwang, S.J.4
-
31
-
-
76149107174
-
Enhancement of wettability and dissolution properties of cilostazol using the supercritical antisolvent process: Effect of various additives
-
Kim MS, Kim JS, Hwang SJ. Enhancement of wettability and dissolution properties of cilostazol using the supercritical antisolvent process: effect of various additives. Chem Pharm Bull. 2010;58:230-233.
-
(2010)
Chem Pharm Bull
, vol.58
, pp. 230-233
-
-
Kim, M.S.1
Kim, J.S.2
Hwang, S.J.3
-
32
-
-
24344461836
-
Hydrogen bonding interactions between adsorbed polymer molecules and crystal surface of acetaminophen
-
Wen H, Morris KR, Park K. Hydrogen bonding interactions between adsorbed polymer molecules and crystal surface of acetaminophen. J Colloid Interface Sci. 2005;290:325-335.
-
(2005)
J Colloid Interface Sci
, vol.290
, pp. 325-335
-
-
Wen, H.1
Morris, K.R.2
Park, K.3
-
33
-
-
84866728928
-
Stabilization of a supersaturated solution of mefenamic acid from a solid dispersion with Eudragit(®) EPO
-
Kojima T, Higashi K, Suzuki T, et al. Stabilization of a supersaturated solution of mefenamic acid from a solid dispersion with Eudragit(®) EPO. Pharm Res. 2012;29:2777-2791.
-
(2012)
Pharm Res
, vol.29
, pp. 2777-2791
-
-
Kojima, T.1
Higashi, K.2
Suzuki, T.3
-
36
-
-
42749095034
-
Cyclodextrins as stabilizers for the preparation of drug nanocrystals by the emulsion solvent diffusion method
-
Makhlof A, Miyazaki Y, Tozuka Y, Takeuchi H. Cyclodextrins as stabilizers for the preparation of drug nanocrystals by the emulsion solvent diffusion method. Int J Pharm. 2008;357:280-285.
-
(2008)
Int J Pharm
, vol.357
, pp. 280-285
-
-
Makhlof, A.1
Miyazaki, Y.2
Tozuka, Y.3
Takeuchi, H.4
-
37
-
-
0141814956
-
Rate of nucleation in condensed systems
-
Turnbull D, Fischer JC. Rate of nucleation in condensed systems. J Chem Phys. 1949;17:71-73.
-
(1949)
J Chem Phys
, vol.17
, pp. 71-73
-
-
Turnbull, D.1
Fischer, J.C.2
-
38
-
-
84878072552
-
-
US Food Drug Administration. Recommended dissolution methods. Available from, Accessed on March 4
-
US Food Drug Administration. Recommended dissolution methods. Available from: http://www.accessdata.fda.gov/scripts/cder/dissolution/index.cfm. Accessed on March 4, 2013.
-
(2013)
-
-
-
39
-
-
1842589355
-
Enhanced oral bioavailability of a poorly water soluble drug PNU-91325 by supersaturatable formulations
-
Gao P, Guyton ME, Huang T, et al. Enhanced oral bioavailability of a poorly water soluble drug PNU-91325 by supersaturatable formulations. Drug Dev Ind Pharm. 2004;30:221-229.
-
(2004)
Drug Dev Ind Pharm
, vol.30
, pp. 221-229
-
-
Gao, P.1
Guyton, M.E.2
Huang, T.3
-
40
-
-
80054697562
-
Pharmaceutical development and preliminary clinical testing of an oral solid dispersion formulation of docetaxel (ModraDoc001)
-
Moes JJ, Koolen SL, Huitema AD, et al. Pharmaceutical development and preliminary clinical testing of an oral solid dispersion formulation of docetaxel (ModraDoc001). Int J Pharm. 2011;420:244-250.
-
(2011)
Int J Pharm
, vol.420
, pp. 244-250
-
-
Moes, J.J.1
Koolen, S.L.2
Huitema, A.D.3
|