Pharmaceutical development and preliminary clinical testing of an oral solid dispersion formulation of docetaxel (ModraDoc001)

International Journal of Pharmaceutics

Volumn 420, Issue 2, 2011, Pages 244-250

  Moes, J J ^a   Koolen, S L W ^a   Huitema, A D R ^a   Schellens, J H M ^a,b   Beijnen, J H ^a,b   Nuijen, B ^a  

^a NETHERLANDS CANCER INSTITUTE   (Netherlands)

^b UTRECHT UNIVERSITY   (Netherlands)

Author keywords

Docetaxel; Oral chemotherapy; PVP; SLS; Ternary solid dispersion

Indexed keywords

DOCETAXEL; POVIDONE; RITONAVIR;

ADVANCED CANCER; ARTICLE; CAPSULE ENDOSCOPE; CLINICAL ARTICLE; CROSSOVER PROCEDURE; DISPERSION; DRUG BIOAVAILABILITY; DRUG BLOOD LEVEL; DRUG CAPSULE; DRUG FORMULATION; DRUG MIXTURE; DRUG SOLUBILITY; FREEZE DRYING; HUMAN; PHASE 1 CLINICAL TRIAL; PRIORITY JOURNAL; RANDOMIZED CONTROLLED TRIAL;

ADJUVANTS, PHARMACEUTIC; ANTINEOPLASTIC AGENTS; BIOLOGICAL AVAILABILITY; CALORIMETRY, DIFFERENTIAL SCANNING; CHEMICAL PRECIPITATION; CROSS-OVER STUDIES; DRUG CARRIERS; DRUG COMPOUNDING; FREEZE DRYING; HUMANS; POVIDONE; POWDERS; RANDOM ALLOCATION; RITONAVIR; SODIUM DODECYL SULFATE; SOLUBILITY; SPECTROSCOPY, FOURIER TRANSFORM INFRARED; SURFACE-ACTIVE AGENTS; TAXOIDS; X-RAY DIFFRACTION;

EID: 80054697562     PISSN: 03785173     EISSN: 18733476     Source Type: Journal    
DOI: 10.1016/j.ijpharm.2011.08.041     Document Type: Article

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