Crosslinking studies in gelatin capsules treated with formaldehyde and in capsules exposed to elevated temperature and humidity

Journal of Pharmaceutical Sciences

Volumn 90, Issue 1, 2001, Pages 79-88

  Ofner Iii, Clyde M ^a,b   Zhang, Y E ^a,b   Jobeck, Valerie C ^a,b   Bowman, Bill J ^a,b  

^a UNIVERSITY OF THE SCIENCES   (United States)

^b Sanofi Research Division   (United States)

Author keywords

Amino group assay; Formaldehyde crosslinking in proteins; Gelatin crosslinking; Gelatin dissolution

Indexed keywords

FORMALDEHYDE; GELATIN; TRINITROBENZENESULFONIC ACID;

ARTICLE; CONTROLLED STUDY; CROSS LINKING; DRUG CAPSULE; DRUG RELEASE; DRUG SOLUBILITY; HUMIDITY; TEMPERATURE;

EID: 0035158246     PISSN: 00223549     EISSN: None     Source Type: Journal    
DOI: 10.1002/1520-6017(200101)90:1<79::AID-JPS9>3.0.CO;2-L     Document Type: Article

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