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Volumn 3, Issue 10, 2012, Pages 739-754

Aptamer-based molecular imaging

Author keywords

aptamer; biosensor; imaging; nucleic acid; protein; small molecule

Indexed keywords

ADENOSINE DIPHOSPHATE; ADENOSINE TRIPHOSPHATE; APTAMER; BIOLOGICAL MARKER; COMPLEMENTARY RNA; HYBRID PROTEIN; MESSENGER RNA; MICRORNA; POTASSIUM ION; RIBOSOME RNA; RNA; S ADENOSYLMETHIONINE; SMALL INTERFERING RNA; SMALL NUCLEAR RNA; TRANSFER RNA; UNTRANSLATED RNA;

EID: 84878025967     PISSN: 1674800X     EISSN: 16748018     Source Type: Journal    
DOI: 10.1007/s13238-012-2072-z     Document Type: Review
Times cited : (18)

References (93)
  • 1
    • 0037130670 scopus 로고    scopus 로고
    • Designed arginine-rich RNA-binding peptides with picomolar affinity
    • Austin, R. J., Xia, T., Ren, J., Takahashi, T. T., and Roberts, R. W. (2002). Designed arginine-rich RNA-binding peptides with picomolar affinity. J Am Chem Soc 124, 10966-10967.
    • (2002) J Am Chem Soc , vol.124 , pp. 10966-10967
    • Austin, R.J.1    Xia, T.2    Ren, J.3    Takahashi, T.T.4    Roberts, R.W.5
  • 2
    • 0344430112 scopus 로고    scopus 로고
    • Aptamers switch on fluorescence of triphenylmethane dyes
    • Babendure, J. R., Adams, S. R., and Tsien, R. Y. (2003). Aptamers switch on fluorescence of triphenylmethane dyes. J Am Chem Soc 125, 14716-14717.
    • (2003) J Am Chem Soc , vol.125 , pp. 14716-14717
    • Babendure, J.R.1    Adams, S.R.2    Tsien, R.Y.3
  • 3
    • 36248973801 scopus 로고    scopus 로고
    • Quantum dot-aptamer conjugates for synchronous cancer imaging, therapy, and sensing of drug delivery based on bi-fluorescence resonance energy transfer
    • Bagalkot, V., Zhang, L., Levy-Nissenbaum, E., Jon, S., Kantoff, P. W., Langer, R., and Farokhzad, O. C. (2007). Quantum dot-aptamer conjugates for synchronous cancer imaging, therapy, and sensing of drug delivery based on bi-fluorescence resonance energy transfer. Nano Lett 7, 3065-3070.
    • (2007) Nano Lett , vol.7 , pp. 3065-3070
    • Bagalkot, V.1    Zhang, L.2    Levy-Nissenbaum, E.3    Jon, S.4    Kantoff, P.W.5    Langer, R.6    Farokhzad, O.C.7
  • 4
    • 67651151407 scopus 로고    scopus 로고
    • Fluorescent probes for live-cell RNA detection
    • Bao, G., Rhee, W. J., and Tsourkas, A. (2009). Fluorescent probes for live-cell RNA detection. Annu Rev Biomed Eng 11, 25-47.
    • (2009) Annu Rev Biomed Eng , vol.11 , pp. 25-47
    • Bao, G.1    Rhee, W.J.2    Tsourkas, A.3
  • 5
    • 79960777825 scopus 로고    scopus 로고
    • In vivo biochemistry: quantifying ion and metabolite levels in individual cells or cultures of yeast
    • Bermejo, C., Ewald, J. C., Lanquar, V., Jones, A. M., and Frommer, W. B. (2011). In vivo biochemistry: quantifying ion and metabolite levels in individual cells or cultures of yeast. Biochem J 438, 1-10.
    • (2011) Biochem J , vol.438 , pp. 1-10
    • Bermejo, C.1    Ewald, J.C.2    Lanquar, V.3    Jones, A.M.4    Frommer, W.B.5
  • 7
    • 33845960252 scopus 로고    scopus 로고
    • Axonal mRNA transport and localized translational regulation of kappa-opioid receptor in primary neurons of dorsal root ganglia
    • Bi, J., Tsai, N. P., Lin, Y. P., Loh, H. H., and Wei, L. N. (2006). Axonal mRNA transport and localized translational regulation of kappa-opioid receptor in primary neurons of dorsal root ganglia. Proc Natl Acad Sci U S A 103, 19919-19924.
    • (2006) Proc Natl Acad Sci U S A , vol.103 , pp. 19919-19924
    • Bi, J.1    Tsai, N.P.2    Lin, Y.P.3    Loh, H.H.4    Wei, L.N.5
  • 8
    • 27144515901 scopus 로고    scopus 로고
    • Movement of eukaryotic mRNAs between polysomes and cytoplasmic processing bodies
    • Brengues, M., Teixeira, D., and Parker, R. (2005). Movement of eukaryotic mRNAs between polysomes and cytoplasmic processing bodies. Science 310, 486-489.
    • (2005) Science , vol.310 , pp. 486-489
    • Brengues, M.1    Teixeira, D.2    Parker, R.3
  • 9
    • 0034544815 scopus 로고    scopus 로고
    • Pre-mRNA processing factors are required for nuclear export
    • Brodsky, A. S., and Silver, P. A. (2000). Pre-mRNA processing factors are required for nuclear export. RNA 6, 1737-1749.
    • (2000) Rna , vol.6 , pp. 1737-1749
    • Brodsky, A.S.1    Silver, P.A.2
  • 10
    • 78649292703 scopus 로고    scopus 로고
    • High-content affinity-based proteomics: unlocking protein biomarker discovery
    • Brody, E. N., Gold, L., Lawn, R. M., Walker, J. J., and Zichi, D. (2010). High-content affinity-based proteomics: unlocking protein biomarker discovery. Expert Rev Mol Diagn 10, 1013-1022.
    • (2010) Expert Rev Mol Diagn , vol.10 , pp. 1013-1022
    • Brody, E.N.1    Gold, L.2    Lawn, R.M.3    Walker, J.J.4    Zichi, D.5
  • 12
    • 0031279943 scopus 로고    scopus 로고
    • In vivo imaging of inflammation using an aptamer inhibitor of human neutrophil elastase
    • Charlton, J., Sennello, J., and Smith, D. (1997). In vivo imaging of inflammation using an aptamer inhibitor of human neutrophil elastase. Chem Biol 4, 809-816.
    • (1997) Chem Biol , vol.4 , pp. 809-816
    • Charlton, J.1    Sennello, J.2    Smith, D.3
  • 13
    • 77955645834 scopus 로고    scopus 로고
    • Design and development of molecular imaging probes
    • Chen, K., and Chen, X. (2010). Design and development of molecular imaging probes. Curr Top Med Chem 10, 1227-1236.
    • (2010) Curr Top Med Chem , vol.10 , pp. 1227-1236
    • Chen, K.1    Chen, X.2
  • 14
    • 84859410570 scopus 로고    scopus 로고
    • Aptamer-mediated nanoparticle-based protein labeling platform for intracellular imaging and tracking endocytosis dynamics
    • Chen, L. Q., Xiao, S. J., Hu, P. P., Peng, L., Ma, J., Luo, L. F., Li, Y. F., and Huang, C. Z. (2012). Aptamer-mediated nanoparticle-based protein labeling platform for intracellular imaging and tracking endocytosis dynamics. Anal Chem 84, 3099-3110.
    • (2012) Anal Chem , vol.84 , pp. 3099-3110
    • Chen, L.Q.1    Xiao, S.J.2    Hu, P.P.3    Peng, L.4    Ma, J.5    Luo, L.F.6    Li, Y.F.7    Huang, C.Z.8
  • 15
    • 77953946319 scopus 로고    scopus 로고
    • Aptamer-based silver nanoparticles used for intracellular protein imaging and single nanoparticle spectral analysis
    • Chen, L. Q., Xiao, S. J., Peng, L., Wu, T., Ling, J., Li, Y. F., and Huang, C. Z. (2010). Aptamer-based silver nanoparticles used for intracellular protein imaging and single nanoparticle spectral analysis. J Phys Chem B 114, 3655-3659.
    • (2010) J Phys Chem B , vol.114 , pp. 3655-3659
    • Chen, L.Q.1    Xiao, S.J.2    Peng, L.3    Wu, T.4    Ling, J.5    Li, Y.F.6    Huang, C.Z.7
  • 16
    • 33646591544 scopus 로고    scopus 로고
    • Transcriptional pulsing of a developmental gene
    • Chubb, J. R., Trcek, T., Shenoy, S. M., and Singer, R. H. (2006). Transcriptional pulsing of a developmental gene. Curr Biol 16, 1018-1025.
    • (2006) Curr Biol , vol.16 , pp. 1018-1025
    • Chubb, J.R.1    Trcek, T.2    Shenoy, S.M.3    Singer, R.H.4
  • 17
    • 20144385597 scopus 로고    scopus 로고
    • Allosteric aptamers: targeted reversibly attenuated probes
    • Cong, X., and Nilsen-Hamilton, M. (2005). Allosteric aptamers: targeted reversibly attenuated probes. Biochemistry 44, 7945-7954.
    • (2005) Biochemistry , vol.44 , pp. 7945-7954
    • Cong, X.1    Nilsen-Hamilton, M.2
  • 19
    • 34547637607 scopus 로고    scopus 로고
    • LambdaN-GFP: an RNA reporter system for live-cell imaging
    • Daigle, N., and Ellenberg, J. (2007). LambdaN-GFP: an RNA reporter system for live-cell imaging. Nat Methods 4, 633-636.
    • (2007) Nat Methods , vol.4 , pp. 633-636
    • Daigle, N.1    Ellenberg, J.2
  • 21
    • 33746611927 scopus 로고    scopus 로고
    • Mutant LYS2 mRNAs retained and degraded in the nucleus of Saccharomyces cerevisiae
    • Das, B., Das, S., and Sherman, F. (2006). Mutant LYS2 mRNAs retained and degraded in the nucleus of Saccharomyces cerevisiae. Proc Natl Acad Sci U S A 103, 10871-10876.
    • (2006) Proc Natl Acad Sci U S A , vol.103 , pp. 10871-10876
    • Das, B.1    Das, S.2    Sherman, F.3
  • 22
    • 44449121279 scopus 로고    scopus 로고
    • A direct role for FMRP in activity-dependent dendritic mRNA transport links filopodial-spine morphogenesis to fragile X syndrome
    • Dictenberg, J. B., Swanger, S. A., Antar, L. N., Singer, R. H., and Bassell, G. J. (2008). A direct role for FMRP in activity-dependent dendritic mRNA transport links filopodial-spine morphogenesis to fragile X syndrome. Dev Cell 14, 926-939.
    • (2008) Dev Cell , vol.14 , pp. 926-939
    • Dictenberg, J.B.1    Swanger, S.A.2    Antar, L.N.3    Singer, R.H.4    Bassell, G.J.5
  • 23
    • 33846958757 scopus 로고    scopus 로고
    • Dynamics of bidirectional transport of Arc mRNA in neuronal dendrites
    • Dynes, J. L., and Steward, O. (2007). Dynamics of bidirectional transport of Arc mRNA in neuronal dendrites. J Comp Neurol 500, 433-447.
    • (2007) J Comp Neurol , vol.500 , pp. 433-447
    • Dynes, J.L.1    Steward, O.2
  • 24
    • 0025074907 scopus 로고
    • In vitro selection of RNA molecules that bind specific ligands
    • Ellington, A. D., and Szostak, J. W. (1990). In vitro selection of RNA molecules that bind specific ligands. Nature 346, 818-822.
    • (1990) Nature , vol.346 , pp. 818-822
    • Ellington, A.D.1    Szostak, J.W.2
  • 25
    • 34247368510 scopus 로고    scopus 로고
    • Identification of nuclear dicing bodies containing proteins for microRNA biogenesis in living Arabidopsis plants
    • Fang, Y., and Spector, D. L. (2007). Identification of nuclear dicing bodies containing proteins for microRNA biogenesis in living Arabidopsis plants. Curr Biol 17, 818-823.
    • (2007) Curr Biol , vol.17 , pp. 818-823
    • Fang, Y.1    Spector, D.L.2
  • 28
    • 80052257765 scopus 로고    scopus 로고
    • Molecular imaging with nucleic acid aptamers
    • Hong, H., Goel, S., Zhang, Y., and Cai, W. (2011). Molecular imaging with nucleic acid aptamers. Curr Med Chem 18, 4195-4205.
    • (2011) Curr Med Chem , vol.18 , pp. 4195-4205
    • Hong, H.1    Goel, S.2    Zhang, Y.3    Cai, W.4
  • 29
    • 75149193491 scopus 로고    scopus 로고
    • A nucleolin-targeted multimodal nanoparticle imaging probe for tracking cancer cells using an aptamer
    • Hwang do, W., Ko, H. Y., Lee, J. H., Kang, H., Ryu, S. H., Song, I. C., Lee, D. S., and Kim, S. (2010). A nucleolin-targeted multimodal nanoparticle imaging probe for tracking cancer cells using an aptamer. J Nucl Med 51, 98-105.
    • (2010) J Nucl Med , vol.51 , pp. 98-105
    • do Hwang, W.1    Ko, H.Y.2    Lee, J.H.3    Kang, H.4    Ryu, S.H.5    Song, I.C.6    Lee, D.S.7    Kim, S.8
  • 30
    • 79959247146 scopus 로고    scopus 로고
    • Aptamer in bioanalytical applications
    • Iliuk, A. B., Hu, L., and Tao, W. A. (2011). Aptamer in bioanalytical applications. Anal Chem 83, 4440-4452.
    • (2011) Anal Chem , vol.83 , pp. 4440-4452
    • Iliuk, A.B.1    Hu, L.2    Tao, W.A.3
  • 31
    • 79953273690 scopus 로고    scopus 로고
    • Validating transcripts with probes and imaging technology
    • Itzkovitz, S., and van Oudenaarden, A. (2011). Validating transcripts with probes and imaging technology. Nat Methods 8, S12-19.
    • (2011) Nat Methods , vol.8
    • Itzkovitz, S.1    van Oudenaarden, A.2
  • 33
    • 0033664254 scopus 로고    scopus 로고
    • In vitro selection of signaling aptamers
    • Jhaveri, S., Rajendran, M., and Ellington, A. D. (2000). In vitro selection of signaling aptamers. Nat Biotechnol 18, 1293-1297.
    • (2000) Nat Biotechnol , vol.18 , pp. 1293-1297
    • Jhaveri, S.1    Rajendran, M.2    Ellington, A.D.3
  • 34
    • 73349118173 scopus 로고    scopus 로고
    • Multiplex imaging of single tumor cells using quantum-dot-conjugated aptamers
    • Kang, W. J., Chae, J. R., Cho, Y. L., Lee, J. D., and Kim, S. (2009a). Multiplex imaging of single tumor cells using quantum-dot-conjugated aptamers. Small 5, 2519-2522.
    • (2009) Small , vol.5 , pp. 2519-2522
    • Kang, W.J.1    Chae, J.R.2    Cho, Y.L.3    Lee, J.D.4    Kim, S.5
  • 35
    • 77951072160 scopus 로고    scopus 로고
    • Bioimaging of geographically adjacent proteins in a single cell by quantum dot-based fluorescent resonance energy transfer
    • Kang, W. J., Ko, M. H., Lee, D. S., and Kim, S. (2009b). Bioimaging of geographically adjacent proteins in a single cell by quantum dot-based fluorescent resonance energy transfer. Proteomics Clin Appl 3, 1383-1388.
    • (2009) Proteomics Clin Appl , vol.3 , pp. 1383-1388
    • Kang, W.J.1    Ko, M.H.2    Lee, D.S.3    Kim, S.4
  • 37
    • 77955542791 scopus 로고    scopus 로고
    • A drug-loaded aptamer-gold nanoparticle bioconjugate for combined CT imaging and therapy of prostate cancer
    • Kim, D., Jeong, Y. Y., and Jon, S. (2010). A drug-loaded aptamer-gold nanoparticle bioconjugate for combined CT imaging and therapy of prostate cancer. ACS Nano 4, 3689-3696.
    • (2010) ACS Nano , vol.4 , pp. 3689-3696
    • Kim, D.1    Jeong, Y.Y.2    Jon, S.3
  • 38
    • 67649361537 scopus 로고    scopus 로고
    • Review: bioanalytical applications of biomolecule-functionalized nanometer-sized doped silica particles
    • Knopp, D., Tang, D., and Niessner, R. (2009). Review: bioanalytical applications of biomolecule-functionalized nanometer-sized doped silica particles. Anal Chim Acta 647, 14-30.
    • (2009) Anal Chim Acta , vol.647 , pp. 14-30
    • Knopp, D.1    Tang, D.2    Niessner, R.3
  • 40
    • 24744465188 scopus 로고    scopus 로고
    • Binary malachite green aptamer for fluorescent detection of nucleic acids
    • Kolpashchikov, D. M. (2005). Binary malachite green aptamer for fluorescent detection of nucleic acids. J Am Chem Soc 127, 12442-12443.
    • (2005) J Am Chem Soc , vol.127 , pp. 12442-12443
    • Kolpashchikov, D.M.1
  • 41
    • 47849121275 scopus 로고    scopus 로고
    • Simultaneous transport of different localized mRNA species revealed by live-cell imaging
    • Lange, S., Katayama, Y., Schmid, M., Burkacky, O., Brauchle, C., Lamb, D. C., and Jansen, R. P. (2008). Simultaneous transport of different localized mRNA species revealed by live-cell imaging. Traffic 9, 1256-1267.
    • (2008) Traffic , vol.9 , pp. 1256-1267
    • Lange, S.1    Katayama, Y.2    Schmid, M.3    Burkacky, O.4    Brauchle, C.5    Lamb, D.C.6    Jansen, R.P.7
  • 42
    • 78649643879 scopus 로고    scopus 로고
    • Combining SELEX screening and rational design to develop light-up fluorophore-RNA aptamer pairs for RNA tagging
    • Lee, J., Lee, K. H., Jeon, J., Dragulescu-Andrasi, A., Xiao, F., and Rao, J. (2010). Combining SELEX screening and rational design to develop light-up fluorophore-RNA aptamer pairs for RNA tagging. ACS Chem Biol 5, 1065-1074.
    • (2010) ACS Chem Biol , vol.5 , pp. 1065-1074
    • Lee, J.1    Lee, K.H.2    Jeon, J.3    Dragulescu-Andrasi, A.4    Xiao, F.5    Rao, J.6
  • 43
    • 46849108283 scopus 로고    scopus 로고
    • Real-time imaging of protein internalization using aptamer conjugates
    • Li, W., Yang, X., Wang, K., Tan, W., He, Y., Guo, Q., Tang, H., and Liu, J. (2008). Real-time imaging of protein internalization using aptamer conjugates. Anal Chem 80, 5002-5008.
    • (2008) Anal Chem , vol.80 , pp. 5002-5008
    • Li, W.1    Yang, X.2    Wang, K.3    Tan, W.4    He, Y.5    Guo, Q.6    Tang, H.7    Liu, J.8
  • 44
    • 80052350734 scopus 로고    scopus 로고
    • Aptamer beacons for visualization of endogenous protein HIV-1 reverse transcriptase in living cells
    • Liang, Y., Zhang, Z., Wei, H., Hu, Q., Deng, J., Guo, D., Cui, Z., and Zhang, X. E. (2011). Aptamer beacons for visualization of endogenous protein HIV-1 reverse transcriptase in living cells. Biosens Bioelectron 28, 270-276.
    • (2011) Biosens Bioelectron , vol.28 , pp. 270-276
    • Liang, Y.1    Zhang, Z.2    Wei, H.3    Hu, Q.4    Deng, J.5    Guo, D.6    Cui, Z.7    Zhang, X.E.8
  • 45
    • 0028060580 scopus 로고
    • Mutations that increase the affinity of a translational repressor for RNA
    • Lim, F., and Peabody, D. S. (1994). Mutations that increase the affinity of a translational repressor for RNA. Nucleic Acids Res 22, 3748-3752.
    • (1994) Nucleic Acids Res , vol.22 , pp. 3748-3752
    • Lim, F.1    Peabody, D.S.2
  • 47
    • 0037338436 scopus 로고    scopus 로고
    • Molecular imaging in living subjects: seeing fundamental biological processes in a new light
    • Massoud, T. F., and Gambhir, S. S. (2003). Molecular imaging in living subjects: seeing fundamental biological processes in a new light. Genes Dev 17, 545-580.
    • (2003) Genes Dev , vol.17 , pp. 545-580
    • Massoud, T.F.1    Gambhir, S.S.2
  • 48
    • 84860794159 scopus 로고    scopus 로고
    • Live imaging of nascent RNA dynamics reveals distinct types of transcriptional pulse regulation
    • Muramoto, T., Cannon, D., Gierlinski, M., Corrigan, A., Barton, G. J., and Chubb, J. R. (2012). Live imaging of nascent RNA dynamics reveals distinct types of transcriptional pulse regulation. Proc Natl Acad Sci U S A 109, 7350-7355.
    • (2012) Proc Natl Acad Sci U S A , vol.109 , pp. 7350-7355
    • Muramoto, T.1    Cannon, D.2    Gierlinski, M.3    Corrigan, A.4    Barton, G.J.5    Chubb, J.R.6
  • 49
    • 79953684293 scopus 로고    scopus 로고
    • Small-molecule fluorescent probes for specific RNA targets
    • Murata, A., Sato, S., Kawazoe, Y., and Uesugi, M. (2011). Small-molecule fluorescent probes for specific RNA targets. Chem Commun (Camb) 47, 4712-4714.
    • (2011) Chem Commun (Camb) , vol.47 , pp. 4712-4714
    • Murata, A.1    Sato, S.2    Kawazoe, Y.3    Uesugi, M.4
  • 51
  • 52
    • 78549255358 scopus 로고    scopus 로고
    • Aptamers embedded in polyacrylamide nanoparticles: a tool for in vivo metabolite sensing
    • Nielsen, L. J., Olsen, L. F., and Ozalp, V. C. (2010). Aptamers embedded in polyacrylamide nanoparticles: a tool for in vivo metabolite sensing. ACS Nano 4, 4361-4370.
    • (2010) ACS Nano , vol.4 , pp. 4361-4370
    • Nielsen, L.J.1    Olsen, L.F.2    Ozalp, V.C.3
  • 53
    • 26644433424 scopus 로고    scopus 로고
    • Aptamers with fluorescence-signaling properties
    • Nutiu, R., and Li, Y. (2005). Aptamers with fluorescence-signaling properties. Methods 37, 16-25.
    • (2005) Methods , vol.37 , pp. 16-25
    • Nutiu, R.1    Li, Y.2
  • 54
    • 0037378193 scopus 로고    scopus 로고
    • RNA aptamers to initiation factor 4A helicase hinder cap-dependent translation by blocking ATP hydrolysis
    • Oguro, A., Ohtsu, T., Svitkin, Y. V., Sonenberg, N., and Nakamura, Y. (2003). RNA aptamers to initiation factor 4A helicase hinder cap-dependent translation by blocking ATP hydrolysis. RNA 9, 394-407.
    • (2003) Rna , vol.9 , pp. 394-407
    • Oguro, A.1    Ohtsu, T.2    Svitkin, Y.V.3    Sonenberg, N.4    Nakamura, Y.5
  • 55
    • 84859982563 scopus 로고    scopus 로고
    • Fluorescence imaging of potassium ions in living cells using a fluorescent probe based on a thrombin binding aptamer-peptide conjugate
    • Ohtsuka, K., Sato, S., Sato, Y., Sota, K., Ohzawa, S., Matsuda, T., Takemoto, K., Takamune, N., Juskowiak, B., Nagai, T., et al. (2012). Fluorescence imaging of potassium ions in living cells using a fluorescent probe based on a thrombin binding aptamer-peptide conjugate. Chem Commun (Camb) 48, 4740-4742.
    • (2012) Chem Commun (Camb) , vol.48 , pp. 4740-4742
    • Ohtsuka, K.1    Sato, S.2    Sato, Y.3    Sota, K.4    Ohzawa, S.5    Matsuda, T.6    Takemoto, K.7    Takamune, N.8    Juskowiak, B.9    Nagai, T.10
  • 56
    • 78650018624 scopus 로고    scopus 로고
    • An aptamer-based nanobiosensor for real-time measurements of ATP dynamics
    • Ozalp, V. C., Nielsen, L. J., and Olsen, L. F. (2010a). An aptamer-based nanobiosensor for real-time measurements of ATP dynamics. Chembiochem 11, 2538-2541.
    • (2010) Chembiochem , vol.11 , pp. 2538-2541
    • Ozalp, V.C.1    Nielsen, L.J.2    Olsen, L.F.3
  • 57
    • 78549252106 scopus 로고    scopus 로고
    • Time-resolved measurements of intracellular ATP in the yeast Saccharomyces cerevisiae using a new type of nanobiosensor
    • Ozalp, V. C., Pedersen, T. R., Nielsen, L. J., and Olsen, L. F. (2010b). Time-resolved measurements of intracellular ATP in the yeast Saccharomyces cerevisiae using a new type of nanobiosensor. J Biol Chem 285, 37579-37588.
    • (2010) J Biol Chem , vol.285 , pp. 37579-37588
    • Ozalp, V.C.1    Pedersen, T.R.2    Nielsen, L.J.3    Olsen, L.F.4
  • 58
    • 84858030373 scopus 로고    scopus 로고
    • Fluorescence imaging of cellular metabolites with RNA
    • Paige, J. S., Nguyen-Duc, T., Song, W., and Jaffrey, S. R. (2012). Fluorescence imaging of cellular metabolites with RNA. Science 335, 1194.
    • (2012) Science , vol.335 , pp. 1194
    • Paige, J.S.1    Nguyen-Duc, T.2    Song, W.3    Jaffrey, S.R.4
  • 59
    • 79960959180 scopus 로고    scopus 로고
    • RNA mimics of green fluorescent protein
    • Paige, J. S., Wu, K. Y., and Jaffrey, S. R. (2011). RNA mimics of green fluorescent protein. Science 333, 642-646.
    • (2011) Science , vol.333 , pp. 642-646
    • Paige, J.S.1    Wu, K.Y.2    Jaffrey, S.R.3
  • 60
    • 79951671135 scopus 로고    scopus 로고
    • Design and application of genetically encoded biosensors
    • Palmer, A. E., Qin, Y., Park, J. G., and McCombs, J. E. (2011). Design and application of genetically encoded biosensors. Trends Biotechnol 29, 144-152.
    • (2011) Trends Biotechnol , vol.29 , pp. 144-152
    • Palmer, A.E.1    Qin, Y.2    Park, J.G.3    McCombs, J.E.4
  • 61
    • 77953250940 scopus 로고    scopus 로고
    • Molecular imaging: current status and emerging strategies
    • Pysz, M. A., Gambhir, S. S., and Willmann, J. K. (2010). Molecular imaging: current status and emerging strategies. Clin Radiol 65, 500-516.
    • (2010) Clin Radiol , vol.65 , pp. 500-516
    • Pysz, M.A.1    Gambhir, S.S.2    Willmann, J.K.3
  • 62
    • 4444285375 scopus 로고    scopus 로고
    • Visualization of RNA-protein interactions in living cells: FMRP and IMP1 interact on mRNAs
    • Rackham, O., and Brown, C. M. (2004). Visualization of RNA-protein interactions in living cells: FMRP and IMP1 interact on mRNAs. EMBO J 23, 3346-3355.
    • (2004) EMBO J , vol.23 , pp. 3346-3355
    • Rackham, O.1    Brown, C.M.2
  • 63
    • 0034257926 scopus 로고    scopus 로고
    • CaMKIIalpha 3′ untranslated region-directed mRNA translocation in living neurons: visualization by GFP linkage
    • Rook, M. S., Lu, M., and Kosik, K. S. (2000). CaMKIIalpha 3′ untranslated region-directed mRNA translocation in living neurons: visualization by GFP linkage. J Neurosci 20, 6385-6393.
    • (2000) J Neurosci , vol.20 , pp. 6385-6393
    • Rook, M.S.1    Lu, M.2    Kosik, K.S.3
  • 64
    • 50249150245 scopus 로고    scopus 로고
    • Transcription monitoring using fused RNA with a dye-binding light-up aptamer as a tag: a blue fluorescent RNA
    • Sando, S., Narita, A., Hayami, M., and Aoyama, Y. (2008). Transcription monitoring using fused RNA with a dye-binding light-up aptamer as a tag: a blue fluorescent RNA. Chem Commun (Camb), 3858-3860.
    • (2008) Chem Commun (Camb) , pp. 3858-3860
    • Sando, S.1    Narita, A.2    Hayami, M.3    Aoyama, Y.4
  • 65
    • 79959450181 scopus 로고    scopus 로고
    • Real-time imaging of cotranscriptional splicing reveals a kinetic model that reduces noise: implications for alternative splicing regulation
    • Schmidt, U., Basyuk, E., Robert, M. C., Yoshida, M., Villemin, J. P., Auboeuf, D., Aitken, S., and Bertrand, E. (2011). Real-time imaging of cotranscriptional splicing reveals a kinetic model that reduces noise: implications for alternative splicing regulation. J Cell Biol 193, 819-829.
    • (2011) J Cell Biol , vol.193 , pp. 819-829
    • Schmidt, U.1    Basyuk, E.2    Robert, M.C.3    Yoshida, M.4    Villemin, J.P.5    Auboeuf, D.6    Aitken, S.7    Bertrand, E.8
  • 67
    • 79952775709 scopus 로고    scopus 로고
    • Activatable aptamer probe for contrast-enhanced in vivo cancer imaging based on cell membrane protein-triggered conformation alteration
    • Shi, H., He, X., Wang, K., Wu, X., Ye, X., Guo, Q., Tan, W., Qing, Z., Yang, X., and Zhou, B. (2011). Activatable aptamer probe for contrast-enhanced in vivo cancer imaging based on cell membrane protein-triggered conformation alteration. Proc Natl Acad Sci U S A 108, 3900-3905.
    • (2011) Proc Natl Acad Sci U S A , vol.108 , pp. 3900-3905
    • Shi, H.1    He, X.2    Wang, K.3    Wu, X.4    Ye, X.5    Guo, Q.6    Tan, W.7    Qing, Z.8    Yang, X.9    Zhou, B.10
  • 68
    • 77957556157 scopus 로고    scopus 로고
    • In vivo fluorescence imaging of tumors using molecular aptamers generated by cell-SELEX
    • Shi, H., Tang, Z., Kim, Y., Nie, H., Huang, Y. F., He, X., Deng, K., Wang, K., and Tan, W. (2010). In vivo fluorescence imaging of tumors using molecular aptamers generated by cell-SELEX. Chem Asian J 5, 2209-2213.
    • (2010) Chem Asian J , vol.5 , pp. 2209-2213
    • Shi, H.1    Tang, Z.2    Kim, Y.3    Nie, H.4    Huang, Y.F.5    He, X.6    Deng, K.7    Wang, K.8    Tan, W.9
  • 71
    • 34247523672 scopus 로고    scopus 로고
    • Fluorescent sensors for specific RNA: a general paradigm using chemistry and combinatorial biology
    • Sparano, B. A., and Koide, K. (2007). Fluorescent sensors for specific RNA: a general paradigm using chemistry and combinatorial biology. J Am Chem Soc 129, 4785-4794.
    • (2007) J Am Chem Soc , vol.129 , pp. 4785-4794
    • Sparano, B.A.1    Koide, K.2
  • 75
    • 0025194307 scopus 로고
    • Systematic evolution of ligands by exponential enrichment: RNA ligands to bacteriophage T4 DNA polymerase
    • Tuerk, C., and Gold, L. (1990). Systematic evolution of ligands by exponential enrichment: RNA ligands to bacteriophage T4 DNA polymerase. Science 249, 505-510.
    • (1990) Science , vol.249 , pp. 505-510
    • Tuerk, C.1    Gold, L.2
  • 76
    • 34250191761 scopus 로고    scopus 로고
    • RNA visualization in live bacterial cells using fluorescent protein complementation
    • Valencia-Burton, M., McCullough, R. M., Cantor, C. R., and Broude, N. E. (2007). RNA visualization in live bacterial cells using fluorescent protein complementation. Nat Methods 4, 421-427.
    • (2007) Nat Methods , vol.4 , pp. 421-427
    • Valencia-Burton, M.1    McCullough, R.M.2    Cantor, C.R.3    Broude, N.E.4
  • 78
    • 79958012143 scopus 로고    scopus 로고
    • Aptamer-conjugated nanobubbles for targeted ultrasound molecular imaging
    • Wang, C. H., Huang, Y. F., and Yeh, C. K. (2011). Aptamer-conjugated nanobubbles for targeted ultrasound molecular imaging. Langmuir 27, 6971-6976.
    • (2011) Langmuir , vol.27 , pp. 6971-6976
    • Wang, C.H.1    Huang, Y.F.2    Yeh, C.K.3
  • 80
    • 70350074288 scopus 로고    scopus 로고
    • Computational and experimental analyses converge to reveal a coherent yet malleable aptamer structure that controls chemical reactivity
    • Wang, T., Hoy, J. A., Lamm, M. H., and Nilsen-Hamilton, M. (2009). Computational and experimental analyses converge to reveal a coherent yet malleable aptamer structure that controls chemical reactivity. J Am Chem Soc 131, 14747-14755.
    • (2009) J Am Chem Soc , vol.131 , pp. 14747-14755
    • Wang, T.1    Hoy, J.A.2    Lamm, M.H.3    Nilsen-Hamilton, M.4
  • 81
    • 77955821689 scopus 로고    scopus 로고
    • Aptamer/graphene oxide nanocomplex for in situ molecular probing in living cells
    • Wang, Y., Li, Z., Hu, D., Lin, C. T., Li, J., and Lin, Y. (2010). Aptamer/graphene oxide nanocomplex for in situ molecular probing in living cells. J Am Chem Soc 132, 9274-9276.
    • (2010) J Am Chem Soc , vol.132 , pp. 9274-9276
    • Wang, Y.1    Li, Z.2    Hu, D.3    Lin, C.T.4    Li, J.5    Lin, Y.6
  • 82
    • 33746492940 scopus 로고    scopus 로고
    • Localization of bicoid mRNA in late oocytes is maintained by continual active transport
    • Weil, T. T., Forrest, K. M., and Gavis, E. R. (2006). Localization of bicoid mRNA in late oocytes is maintained by continual active transport. Dev Cell 11, 251-262.
    • (2006) Dev Cell , vol.11 , pp. 251-262
    • Weil, T.T.1    Forrest, K.M.2    Gavis, E.R.3
  • 83
    • 41649110649 scopus 로고    scopus 로고
    • Imaging in the era of molecular oncology
    • Weissleder, R., and Pittet, M. J. (2008). Imaging in the era of molecular oncology. Nature 452, 580-589.
    • (2008) Nature , vol.452 , pp. 580-589
    • Weissleder, R.1    Pittet, M.J.2
  • 84
    • 46049108242 scopus 로고    scopus 로고
    • Cell-specific internalization study of an aptamer from whole cell selection
    • Xiao, Z., Shangguan, D., Cao, Z., Fang, X., and Tan, W. (2008). Cell-specific internalization study of an aptamer from whole cell selection. Chemistry 14, 1769-1775.
    • (2008) Chemistry , vol.14 , pp. 1769-1775
    • Xiao, Z.1    Shangguan, D.2    Cao, Z.3    Fang, X.4    Tan, W.5
  • 85
    • 63049130350 scopus 로고    scopus 로고
    • Single-molecule imaging of beta-actin mRNAs in the cytoplasm of a living cell
    • Yamagishi, M., Ishihama, Y., Shirasaki, Y., Kurama, H., and Funatsu, T. (2009). Single-molecule imaging of beta-actin mRNAs in the cytoplasm of a living cell. Exp Cell Res 315, 1142-1147.
    • (2009) Exp Cell Res , vol.315 , pp. 1142-1147
    • Yamagishi, M.1    Ishihama, Y.2    Shirasaki, Y.3    Kurama, H.4    Funatsu, T.5
  • 87
    • 79955577661 scopus 로고    scopus 로고
    • RNA Detection in live bacterial cells using fluorescent protein complementation triggered by interaction of two RNA aptamers with two RNA-binding peptides
    • Yiu, H.-W., Demidov, V. V., Toran, P., Cantor, C. R., and Broude, N. E. (2011). RNA Detection in live bacterial cells using fluorescent protein complementation triggered by interaction of two RNA aptamers with two RNA-binding peptides. Pharmaceuticals 4, 494-508.
    • (2011) Pharmaceuticals , vol.4 , pp. 494-508
    • Yiu, H.-W.1    Demidov, V.V.2    Toran, P.3    Cantor, C.R.4    Broude, N.E.5
  • 88
    • 80051500899 scopus 로고    scopus 로고
    • Image-guided prostate cancer therapy using aptamer-functionalized thermally cross-linked superparamagnetic iron oxide nanoparticles
    • Yu, M. K., Kim, D., Lee, I. H., So, J. S., Jeong, Y. Y., and Jon, S. (2011). Image-guided prostate cancer therapy using aptamer-functionalized thermally cross-linked superparamagnetic iron oxide nanoparticles. Small 7, 2241-2249.
    • (2011) Small , vol.7 , pp. 2241-2249
    • Yu, M.K.1    Kim, D.2    Lee, I.H.3    So, J.S.4    Jeong, Y.Y.5    Jon, S.6
  • 89
    • 0030968459 scopus 로고    scopus 로고
    • Contribution of the C-terminal tail of U1A RBD1 to RNA recognition and protein stability
    • Zeng, Q., and Hall, K. B. (1997). Contribution of the C-terminal tail of U1A RBD1 to RNA recognition and protein stability. RNA 3, 303-314.
    • (1997) Rna , vol.3 , pp. 303-314
    • Zeng, Q.1    Hall, K.B.2
  • 91
    • 70350001730 scopus 로고    scopus 로고
    • Aptamer nano-flares for molecular detection in living cells
    • Zheng, D., Seferos, D. S., Giljohann, D. A., Patel, P. C., and Mirkin, C. A. (2009). Aptamer nano-flares for molecular detection in living cells. Nano Lett 9, 3258-3261.
    • (2009) Nano Lett , vol.9 , pp. 3258-3261
    • Zheng, D.1    Seferos, D.S.2    Giljohann, D.A.3    Patel, P.C.4    Mirkin, C.A.5
  • 92
    • 78650191633 scopus 로고    scopus 로고
    • Aptamer-based molecular recognition for biosensor development
    • Zhou, J., Battig, M. R., and Wang, Y. (2010). Aptamer-based molecular recognition for biosensor development. Anal Bioanal Chem 398, 2471-2480.
    • (2010) Anal Bioanal Chem , vol.398 , pp. 2471-2480
    • Zhou, J.1    Battig, M.R.2    Wang, Y.3
  • 93
    • 50249124582 scopus 로고    scopus 로고
    • In vivo imaging of oskar mRNA transport reveals the mechanism of posterior localization
    • Zimyanin, V. L., Belaya, K., Pecreaux, J., Gilchrist, M. J., Clark, A., Davis, I., and St Johnston, D. (2008). In vivo imaging of oskar mRNA transport reveals the mechanism of posterior localization. Cell 134, 843-853.
    • (2008) Cell , vol.134 , pp. 843-853
    • Zimyanin, V.L.1    Belaya, K.2    Pecreaux, J.3    Gilchrist, M.J.4    Clark, A.5    Davis, I.6    St. Johnston, D.7


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