Cas utilizes Nck2 to activate Cdc42 and regulate cell polarization during cell migration in response to wound healing

FEBS Journal

Volumn 277, Issue 17, 2010, Pages 3502-3513

  Funasaka, Kohei ^a   Ito, Satoko ^a   Hasegawa, Hitoki ^a   Goldberg, Gary S ^b   Hirooka, Yoshiki ^a   Goto, Hidemi ^a   Hamaguchi, Michinari ^a   Senga, Takeshi ^a  

^a NAGOYA UNIVERSITY GRADUATE SCHOOL OF MEDICINE   (Japan)

^b UNIVERSITY OF MEDICINE AND DENTISTRY OF NEW JERSEY   (United States)

Author keywords

Cas; Cdc42; Crk; Nck; polarity

Indexed keywords

CELLULAR APOPTOSIS SUSCEPTIBILITY PROTEIN; CRK LIKE PROTEIN; CRKII PROTEIN; NCK PROTEIN; NCK2 PROTEIN; PROTEIN CDC42; RAC1 PROTEIN; UNCLASSIFIED DRUG; BCAR1 PROTEIN, MOUSE; CRK ASSOCIATED SUBSTRATE PROTEIN; NCK2 PROTEIN, MOUSE; ONCOPROTEIN; SIGNAL TRANSDUCING ADAPTOR PROTEIN;

ANIMAL CELL; ARTICLE; CELL MIGRATION; CELL MOTILITY; CELL POLARITY; CONTROLLED STUDY; EMBRYO; ENZYME ACTIVATION; MOLECULAR INTERACTION; MOLECULAR MECHANICS; MOUSE; NONHUMAN; NUCLEOTIDE SEQUENCE; PRIORITY JOURNAL; SIGNAL TRANSDUCTION; WOUND HEALING; ANIMAL; CELL LINE; CELL MOTION; KNOCKOUT MOUSE; METABOLISM;

ADAPTOR PROTEINS, SIGNAL TRANSDUCING; ANIMALS; CDC42 GTP-BINDING PROTEIN; CELL LINE; CELL MOVEMENT; CELL POLARITY; CRK-ASSOCIATED SUBSTRATE PROTEIN; MICE; MICE, KNOCKOUT; ONCOGENE PROTEINS; PROTO-ONCOGENE PROTEINS C-CRK; WOUND HEALING;

EID: 77955809108     PISSN: 1742464X     EISSN: 17424658     Source Type: Journal    
DOI: 10.1111/j.1742-4658.2010.07752.x     Document Type: Article

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