Specific tyrosine phosphorylation sites on cortactin regulate Nck1-dependent actin polymerization in invadopodia

Journal of Cell Science

Volumn 123, Issue 21, 2010, Pages 3662-3673

  Oser, Matthew ^a   Mader, Christopher C ^b,c   Gil Henn, Hava ^c   Magalhaes, Marco ^a   Bravo Cordero, Jose Javier ^a   Koleske, Anthony J ^c   Condeelis, John ^a  

^a ALBERT EINSTEIN COLLEGE OF MEDICINE   (United States)

^b YALE UNIVERSITY SCHOOL OF MEDICINE   (United States)

^c YALE UNIVERSITY   (United States)

Author keywords

Cancer invasion; Cortactin; Invadopodia; Nck1; Phosphorylation; SH2

Indexed keywords

CORTACTIN; NCK PROTEIN; PHOSPHOTYROSINE; PROTEIN SH2; TYROSINE;

ACTIN FILAMENT; ACTIN POLYMERIZATION; ARTICLE; CANCER INVASION; CARCINOMA CELL; CELL INVASION; CONTROLLED STUDY; FLUORESCENCE RESONANCE ENERGY TRANSFER; GENE MUTATION; HUMAN; HUMAN CELL; HUMAN TISSUE; PRIORITY JOURNAL; PROTEIN BINDING; PROTEIN DEGRADATION; PROTEIN DOMAIN; PROTEIN EXPRESSION; PROTEIN PHOSPHORYLATION; PROTEIN PROTEIN INTERACTION; REGULATORY MECHANISM;

ACTINS; ADAPTOR PROTEINS, SIGNAL TRANSDUCING; BREAST NEOPLASMS; CARCINOMA; CELL LINE, TUMOR; CORTACTIN; CYTOSKELETON; FEMALE; HUMANS; NEOPLASM INVASIVENESS; ONCOGENE PROTEINS; PHOSPHORYLATION; PROTEIN BINDING; PSEUDOPODIA; SRC HOMOLOGY DOMAINS; TYROSINE;

EID: 78149323428     PISSN: 00219533     EISSN: None     Source Type: Journal    
DOI: 10.1242/jcs.068163     Document Type: Article

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