메뉴 건너뛰기




Volumn 105, Issue 1, 2012, Pages 149-154

Characterization of a naturally occurring degradation product of the LDL receptor

Author keywords

Cleavage; Degradation; LDL receptor; Ligand binding domain; Truncation

Indexed keywords

LOW DENSITY LIPOPROTEIN RECEPTOR; TRUNCATED LOW DENSITY LIPOPROTEIN RECEPTOR; UNCLASSIFIED DRUG;

EID: 84855346383     PISSN: 10967192     EISSN: 10967206     Source Type: Journal    
DOI: 10.1016/j.ymgme.2011.10.008     Document Type: Article
Times cited : (15)

References (23)
  • 1
    • 0000600880 scopus 로고    scopus 로고
    • Familial hypercholesterolemia
    • McGraw-Hill, New York, C.R. Scriver, A.L. Beaudet, W.S. Sly, D. Valle (Eds.)
    • Goldstein J.L., Hobbs H.H., Brown M.S. Familial hypercholesterolemia. The Metabolic & Molecular Basis of Inherited Disease 2001, 2863-2914. McGraw-Hill, New York. C.R. Scriver, A.L. Beaudet, W.S. Sly, D. Valle (Eds.).
    • (2001) The Metabolic & Molecular Basis of Inherited Disease , pp. 2863-2914
    • Goldstein, J.L.1    Hobbs, H.H.2    Brown, M.S.3
  • 2
    • 0022259920 scopus 로고
    • The LDL receptor gene: a mosaic of exons shared with different proteins
    • SÜdhof T.C., Goldstein J.L., Brown M.S., Russell D.W. The LDL receptor gene: a mosaic of exons shared with different proteins. Science 1985, 228:815-822.
    • (1985) Science , vol.228 , pp. 815-822
    • Südhof, T.C.1    Goldstein, J.L.2    Brown, M.S.3    Russell, D.W.4
  • 4
    • 0020420335 scopus 로고
    • Posttranslational processing of the LDL receptor and its genetic disruption in familial hypercholesterolemia
    • Tolleshaug H., Goldstein J.L., Schneider W.J., Brown M.S. Posttranslational processing of the LDL receptor and its genetic disruption in familial hypercholesterolemia. Cell 1982, 30:715-724.
    • (1982) Cell , vol.30 , pp. 715-724
    • Tolleshaug, H.1    Goldstein, J.L.2    Schneider, W.J.3    Brown, M.S.4
  • 5
    • 0022549920 scopus 로고
    • A receptor-mediated pathway for cholesterol homeostasis
    • Brown M.S., Goldstein J.L. A receptor-mediated pathway for cholesterol homeostasis. Science 1986, 232:34-47.
    • (1986) Science , vol.232 , pp. 34-47
    • Brown, M.S.1    Goldstein, J.L.2
  • 7
    • 0020724143 scopus 로고
    • Recycling receptors: the round-trip itinerary of migrant membrane proteins
    • Brown M.S., Anderson R.G., Goldstein J.L. Recycling receptors: the round-trip itinerary of migrant membrane proteins. Cell 1983, 32:663-667.
    • (1983) Cell , vol.32 , pp. 663-667
    • Brown, M.S.1    Anderson, R.G.2    Goldstein, J.L.3
  • 8
    • 0030758231 scopus 로고    scopus 로고
    • LDL-receptor structure. Calcium cages, acid baths and recycling receptors
    • Brown M.S., Herz J., Goldstein J.L. LDL-receptor structure. Calcium cages, acid baths and recycling receptors. Nature 1997, 388:629-630.
    • (1997) Nature , vol.388 , pp. 629-630
    • Brown, M.S.1    Herz, J.2    Goldstein, J.L.3
  • 9
    • 70449368195 scopus 로고    scopus 로고
    • The unique role of proprotein convertase subtilisin/kexin 9 in cholesterol homeostasis
    • Mousavi S.A., Berge K.E., Leren T.P. The unique role of proprotein convertase subtilisin/kexin 9 in cholesterol homeostasis. J. Intern. Med. 2009, 266:507-519.
    • (2009) J. Intern. Med. , vol.266 , pp. 507-519
    • Mousavi, S.A.1    Berge, K.E.2    Leren, T.P.3
  • 11
    • 0021932361 scopus 로고
    • Internalization-defective LDL receptors produced by genes with nonsense and frameshift mutations that truncate the cytoplasmic domain
    • Lehrman M.A., Goldstein J.L., Brown M.S., Russell D.W., Schneider W.J. Internalization-defective LDL receptors produced by genes with nonsense and frameshift mutations that truncate the cytoplasmic domain. Cell 1985, 41:735-743.
    • (1985) Cell , vol.41 , pp. 735-743
    • Lehrman, M.A.1    Goldstein, J.L.2    Brown, M.S.3    Russell, D.W.4    Schneider, W.J.5
  • 12
    • 0026762461 scopus 로고
    • Characterization of two new point mutations in the low density lipoprotein receptor genes of an English patient with homozygous familial hypercholesterolemia
    • Webb J.C., Sun X.M., Patel D.D., McCarthy S.N., Knight B.L., Soutar A.K. Characterization of two new point mutations in the low density lipoprotein receptor genes of an English patient with homozygous familial hypercholesterolemia. J. Lipid Res. 1992, 33:689-698.
    • (1992) J. Lipid Res. , vol.33 , pp. 689-698
    • Webb, J.C.1    Sun, X.M.2    Patel, D.D.3    McCarthy, S.N.4    Knight, B.L.5    Soutar, A.K.6
  • 13
    • 72449203600 scopus 로고    scopus 로고
    • Loss-of-function mutation R46L in the PCSK9 gene has little impact on the levels of total serum cholesterol in familial hypercholesterolemia heterozygotes
    • Strøm T.B., Holla Ø.L., Cameron J., Berge K.E., Leren T.P. Loss-of-function mutation R46L in the PCSK9 gene has little impact on the levels of total serum cholesterol in familial hypercholesterolemia heterozygotes. Clin. Chim. Acta 2010, 411:229-233.
    • (2010) Clin. Chim. Acta , vol.411 , pp. 229-233
    • Strøm, T.B.1    Holla, Ø.L.2    Cameron, J.3    Berge, K.E.4    Leren, T.P.5
  • 14
    • 33644863652 scopus 로고    scopus 로고
    • Retention of mutant low density lipoprotein receptor in endoplasmic reticulum (ER) leads to ER stress
    • Sørensen S., Ranheim T., Bakken K.S., Leren T.P., Kulseth M.A. Retention of mutant low density lipoprotein receptor in endoplasmic reticulum (ER) leads to ER stress. J. Biol. Chem. 2006, 281:468-476.
    • (2006) J. Biol. Chem. , vol.281 , pp. 468-476
    • Sørensen, S.1    Ranheim, T.2    Bakken, K.S.3    Leren, T.P.4    Kulseth, M.A.5
  • 15
    • 34247172594 scopus 로고    scopus 로고
    • 4-Phenylbutyrate restores the functionality of a misfolded mutant low-density lipoprotein receptor
    • Tveten K., Holla Ø.L., Ranheim T., Berge K.E., Leren T.P., Kulseth M.A. 4-Phenylbutyrate restores the functionality of a misfolded mutant low-density lipoprotein receptor. FEBS J. 2007, 274:1881-1893.
    • (2007) FEBS J. , vol.274 , pp. 1881-1893
    • Tveten, K.1    Holla, Ø.L.2    Ranheim, T.3    Berge, K.E.4    Leren, T.P.5    Kulseth, M.A.6
  • 17
    • 65249134100 scopus 로고    scopus 로고
    • The effect of bafilomycin A1 and protease inhibitors on the degradation and recycling of a Class 5-mutant LDLR
    • Tveten K., Ranheim T., Berge K.E., Leren T.P., Kulseth M.A. The effect of bafilomycin A1 and protease inhibitors on the degradation and recycling of a Class 5-mutant LDLR. Acta Biochim. Biophys. Sin. 2009, 4:246-255.
    • (2009) Acta Biochim. Biophys. Sin. , vol.4 , pp. 246-255
    • Tveten, K.1    Ranheim, T.2    Berge, K.E.3    Leren, T.P.4    Kulseth, M.A.5
  • 18
    • 0019796014 scopus 로고
    • Acetoacetylated lipoproteins used to distinguish fibroblasts from macrophages in vitro by fluorescence microscopy
    • Pitas R.E., Innerarity T.L., Weinstein J.N., Mahley R.W. Acetoacetylated lipoproteins used to distinguish fibroblasts from macrophages in vitro by fluorescence microscopy. Arteriosclerosis 1981, 1:177-185.
    • (1981) Arteriosclerosis , vol.1 , pp. 177-185
    • Pitas, R.E.1    Innerarity, T.L.2    Weinstein, J.N.3    Mahley, R.W.4
  • 19
    • 0024806811 scopus 로고
    • Different combinations of cysteine-rich repeats mediate binding of low density lipoprotein receptor to two different proteins
    • Russell D.W., Brown M.S., Goldstein J.L. Different combinations of cysteine-rich repeats mediate binding of low density lipoprotein receptor to two different proteins. J. Biol. Chem. 1989, 264:21682-21688.
    • (1989) J. Biol. Chem. , vol.264 , pp. 21682-21688
    • Russell, D.W.1    Brown, M.S.2    Goldstein, J.L.3
  • 20
    • 84855357711 scopus 로고    scopus 로고
    • http://www.rndsystems.com/pdf/2148-LD_CF.pdf.
  • 23
    • 51349161358 scopus 로고    scopus 로고
    • Structural requirements for PCSK9-mediated degradation of the low-density lipoprotein receptor
    • Zhang D.W., Garuti R., Tang W.J., Cohen J.C., Hobbs H.H. Structural requirements for PCSK9-mediated degradation of the low-density lipoprotein receptor. Proc. Natl. Acad. Sci. USA 2008, 105:13045-13050.
    • (2008) Proc. Natl. Acad. Sci. USA , vol.105 , pp. 13045-13050
    • Zhang, D.W.1    Garuti, R.2    Tang, W.J.3    Cohen, J.C.4    Hobbs, H.H.5


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.