Directed DNA Shuffling of Retrovirus and Retrotransposon Integrase Protein Domains

PLoS ONE

Volumn 8, Issue 5, 2013, Pages

  Qi, Xiaojie ^a,f   Vargas, Edwin ^a,b   Larsen, Liza ^a   Knapp, Whitney ^a   Hatfield, G Wesley ^a,c,d,e   Lathrop, Richard ^a,b,d,e   Sandmeyer, Suzanne ^a,c  

^a UNIVERSITY OF CALIFORNIA   (United States)

^b Irvine   (United States)

^c University of California at Irvine   (United States)

^d UNIVERSITY OF CALIFORNIA   (United States)

^e NONE   (United States)

^f Fred Hutchinson Cancer Research Center   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CHIMERIC PROTEIN; DNA DIRECTED RNA POLYMERASE III; INTEGRASE; HYBRID PROTEIN; OLIGONUCLEOTIDE; REVERSE TRANSCRIPTASE TY3, S CEREVISIAE; RNA DIRECTED DNA POLYMERASE; SACCHAROMYCES CEREVISIAE PROTEIN;

AMINO TERMINAL SEQUENCE; ARTICLE; BASE PAIRING; CARBOXY TERMINAL SEQUENCE; DNA INTEGRATION; DNA SHUFFLING; ENZYME ACTIVE SITE; ENZYME ACTIVITY; ENZYME SPECIFICITY; FUNGAL GENE; GENE SEQUENCE; HUMAN IMMUNODEFICIENCY VIRUS; MOLECULAR LIBRARY; POLYMERASE CHAIN REACTION; PROTEIN DOMAIN; PROTEIN FUNCTION; PROTEIN PROTEIN INTERACTION; PROTEIN TARGETING; RETROPOSON; RETROVIRUS; SACCHAROMYCES CEREVISIAE; SPUMA VIRUS; TRANSCRIPTION INITIATION; VIRUS GENE; AMINO ACID SEQUENCE; DIRECTED MOLECULAR EVOLUTION; ENZYMOLOGY; GENE LIBRARY; GENETICS; HUMAN IMMUNODEFICIENCY VIRUS 1; METABOLISM; MOLECULAR GENETICS; NUCLEOTIDE SEQUENCE; PROCEDURES; PROTEIN ENGINEERING; SEQUENCE ALIGNMENT;

AMINO ACID SEQUENCE; BASE SEQUENCE; DIRECTED MOLECULAR EVOLUTION; GENE LIBRARY; HIV-1; INTEGRASES; MOLECULAR SEQUENCE DATA; OLIGONUCLEOTIDES; PROTEIN ENGINEERING; RECOMBINANT FUSION PROTEINS; RNA-DIRECTED DNA POLYMERASE; SACCHAROMYCES CEREVISIAE PROTEINS; SEQUENCE ALIGNMENT; SPUMAVIRUS; SUBSTRATE SPECIFICITY;

EID: 84877863317     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0063957     Document Type: Article

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