Role of the Nonspecific DNA-binding Region and α Helices within the Core Domain of Retroviral Integrase in Selecting Target DNA Sites for Integration

Journal of Biological Chemistry

Volumn 276, Issue 49, 2001, Pages 45848-45855

  Appa, Rupa Shree ^b   Shin, Cha Gyun ^b   Lee, Philip ^b   Chow, Samson A ^a  

^a UNIVERSITY OF CALIFORNIA   (United States)

^b NONE

Author keywords

[No Author keywords available]

Indexed keywords

AMINO ACIDS; GENES; PROTEINS; VIRUSES;

CHIMERIC INTEGRASES;

DNA;

INTEGRASE; RETROVIRAL INTEGRASE; UNCLASSIFIED DRUG; CHIMERIC PROTEIN; PRIMER DNA; VIRUS DNA;

ALPHA 2 HELIX; ALPHA 3 HELIX; ALPHA 4 HELIX; ALPHA HELIX; AMINO ACID SEQUENCE; ARTICLE; BINDING SITE; CHIMERA; CHROMOSOME; CORE DOMAIN; DNA BINDING; DNA INTEGRATION; FELINE IMMUNODEFICIENCY VIRUS; HUMAN IMMUNODEFICIENCY VIRUS 1; NONHUMAN; PRIORITY JOURNAL; PROTEIN DOMAIN; PROTEIN MOTIF; RETROVIRUS; TARGET SITE SPECIFYING MOTIF; VIRUS GENOME; CATALYSIS; CHEMISTRY; ENZYMOLOGY; ISOLATION AND PURIFICATION; METABOLISM; MOLECULAR GENETICS; NUCLEOTIDE SEQUENCE; PHYSIOLOGY; POLYMERASE CHAIN REACTION; SEQUENCE HOMOLOGY; VIRUS DNA CELL DNA INTERACTION; WESTERN BLOTTING;

FELIDAE; FELINE IMMUNODEFICIENCY VIRUS; FUNGI; HUMAN IMMUNODEFICIENCY VIRUS; HUMAN IMMUNODEFICIENCY VIRUS 1; MYXOGASTRIA; RNA VIRUSES; STAPHYLOCOCCUS PHAGE 187; UNIDENTIFIED RETROVIRUS;

AMINO ACID MOTIFS; AMINO ACID SEQUENCE; BASE SEQUENCE; BINDING SITES; BLOTTING, WESTERN; CATALYSIS; CHIMERIC PROTEINS; DNA PRIMERS; DNA, VIRAL; HIV INTEGRASE; HIV-1; IMMUNODEFICIENCY VIRUS, FELINE; MOLECULAR SEQUENCE DATA; POLYMERASE CHAIN REACTION; SEQUENCE HOMOLOGY, AMINO ACID; SUPPORT, U.S. GOV'T, P.H.S.; VIRUS INTEGRATION;

EID: 0035824646     PISSN: 00219258     EISSN: None     Source Type: Journal    
DOI: 10.1074/jbc.M107365200     Document Type: Article

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