PML RING suppresses oncogenic transformation by reducing the affinity of eIF4E for mRNA

EMBO Journal

Volumn 20, Issue 16, 2001, Pages 4547-4559

  Cohen, N ^a   Sharma, M ^a   Kentsis, A ^a   Perez, J M ^a   Strudwick, S ^a   Borden, K L B ^a  

^a NEW YORK UNIVERSITY   (United States)

Author keywords

Eukaryotic initiation factor 4E; Nuclear domain 10; PML oncogenic domains; Promyelocytic leukemia; RING

Indexed keywords

CYCLIN D1; INITIATION FACTOR 4E; PROMYELOCYTIC LEUKEMIA PROTEIN; UNCLASSIFIED DRUG;

APOPTOSIS; ARTICLE; BINDING AFFINITY; CANCER CELL CULTURE; CIRCULAR DICHROISM; CONFORMATIONAL TRANSITION; DROSOPHILA MELANOGASTER; MALIGNANT TRANSFORMATION; PRIORITY JOURNAL; PROMYELOCYTIC LEUKEMIA; PROTEIN DOMAIN; PROTEIN LOCALIZATION; RNA BINDING;

CELL NUCLEUS; CELL TRANSFORMATION, NEOPLASTIC; DINUCLEOSIDE PHOSPHATES; EUKARYOTIC INITIATION FACTOR-4E; HUMANS; K562 CELLS; LEUKEMIA; NEOPLASM PROTEINS; NUCLEAR PROTEINS; PEPTIDE INITIATION FACTORS; PROTEIN CONFORMATION; RNA CAPS; RNA, MESSENGER; TRANSCRIPTION FACTORS; TUMOR CELLS, CULTURED; TUMOR SUPPRESSOR PROTEINS; U937 CELLS; ZINC FINGERS;

DROSOPHILA MELANOGASTER; EUKARYOTA; MELANOGASTER;

EID: 0035881526     PISSN: 02614189     EISSN: None     Source Type: Journal    
DOI: 10.1093/emboj/20.16.4547     Document Type: Article

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