Repressor binding to a dorsal regulatory site traps human eIF4E in a high cap-affinity state

EMBO Journal

Volumn 18, Issue 14, 1999, Pages 4068-4075

  Ptushkina, Marina ^a   Von Der Haar, Tobias ^a   Karim, Muhammad Manjurul ^a   Hughes, John M X ^a   McCarthy, John E G ^a  

^a UNIVERSITY OF MANCHESTER   (United Kingdom)

Author keywords

Cap binding affinity; Eeukaryotic translation initiation factors 4E and 4G; eIF4E dorsal binding site; Gene expression; Regulation by 4E binding proteins

Indexed keywords

BINDING PROTEIN; INITIATION FACTOR; MESSENGER RNA; REPRESSOR PROTEIN;

AMINO ACID SEQUENCE; ARTICLE; CONTROLLED STUDY; EUKARYOTIC CELL; GENE EXPRESSION REGULATION; MOLECULAR INTERACTION; MOLECULAR MODEL; PRIORITY JOURNAL; PROTEIN PROTEIN INTERACTION; PROTEIN RNA BINDING; REGULATOR GENE; REPRESSOR GENE; SIGNAL TRANSDUCTION; TRANSLATION INITIATION; TRANSLATION REGULATION;

ADAPTOR PROTEINS, SIGNAL TRANSDUCING; ALLOSTERIC REGULATION; AMINO ACID SEQUENCE; BINDING SITES; CARRIER PROTEINS; EUKARYOTIC INITIATION FACTOR-4E; EUKARYOTIC INITIATION FACTOR-4F; EUKARYOTIC INITIATION FACTOR-4G; EUKARYOTIC INITIATION FACTORS; HUMANS; KINETICS; MODELS, MOLECULAR; MOLECULAR SEQUENCE DATA; MUTATION; PEPTIDE INITIATION FACTORS; PHOSPHOPROTEINS; PROTEIN BINDING; RECOMBINANT FUSION PROTEINS; REPRESSOR PROTEINS; RESPONSE ELEMENTS; RNA; RNA CAPS; RNA-BINDING PROTEINS; SACCHAROMYCES CEREVISIAE;

EID: 0033565233     PISSN: 02614189     EISSN: None     Source Type: Journal    
DOI: 10.1093/emboj/18.14.4068     Document Type: Article

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