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Volumn 28, Issue 8, 2009, Pages 1087-1098

Molecular dissection of the eukaryotic initiation factor 4E (eIF4E) export-competent RNP

Author keywords

EIF4E; LRPPRC; Nuclear mRNA export; PML

Indexed keywords

ADAPTOR PROTEIN; INITIATION FACTOR 4E; MESSENGER RNA; PROTEIN; PROTEIN LRPPRC; RECEPTOR PROTEIN; REF ALY PROTEIN; RIBONUCLEOPROTEIN; TAP NXF1 PROTEIN; UNCLASSIFIED DRUG;

EID: 67349210662     PISSN: 02614189     EISSN: 14602075     Source Type: Journal    
DOI: 10.1038/emboj.2009.53     Document Type: Article
Times cited : (115)

References (37)
  • 1
    • 33845626622 scopus 로고    scopus 로고
    • Human mRNA export machinery recruited to the 5' end of mRNA
    • Cheng H, Dufu K, Lee CS, Hsu JL, Dias A, Reed R (2006) Human mRNA export machinery recruited to the 5' end of mRNA. Cell 127:1389-1400
    • (2006) Cell , vol.127 , pp. 1389-1400
    • Cheng, H.1    Dufu, K.2    Lee, C.S.3    Hsu, J.L.4    Dias, A.5    Reed, R.6
  • 2
    • 0035881526 scopus 로고    scopus 로고
    • PML RING suppresses oncogenic transformation by redu- cing the affinity of eIF4E for mRNA
    • Cohen N, Sharma M, Kentsis A, Perez JM, Strudwick S, Borden KL (2001) PML RING suppresses oncogenic transformation by redu- cing the affinity of eIF4E for mRNA. EMBO J 20: 4547-4559
    • (2001) EMBO J , vol.20 , pp. 4547-4559
    • Cohen, N.1    Sharma, M.2    Kentsis, A.3    Perez, J.M.4    Strudwick, S.5    Borden, K.L.6
  • 5
    • 33846648989 scopus 로고    scopus 로고
    • Controlling gene expression through RNA regulons: The role of the eukaryotic translation initiation factor eIF4E
    • Culjkovic B, Topisirovic I, Borden KL (2007) Controlling gene expression through RNA regulons: the role of the eukaryotic translation initiation factor eIF4E. Cell Cycle 6: 65-69
    • (2007) Cell Cycle , vol.6 , pp. 65-69
    • Culjkovic, B.1    Topisirovic, I.2    Borden, K.L.3
  • 8
    • 2342489456 scopus 로고    scopus 로고
    • eIF-4E expression and its role in malignancies and metastases
    • De Benedetti A, Graff JR (2004) eIF-4E expression and its role in malignancies and metastases. Oncogene 23: 3189-3199
    • (2004) Oncogene , vol.23 , pp. 3189-3199
    • De Benedetti, A.1    Graff, J.R.2
  • 9
    • 0034660062 scopus 로고    scopus 로고
    • A novel shuttling protein, 4E-T, mediates the nuclear import of the mRNA 5' cap-binding protein, eIF4E
    • Dostie J, Ferraiuolo M, Pause A, Adam SA, Sonenberg N (2000) A novel shuttling protein, 4E-T, mediates the nuclear import of the mRNA 5' cap-binding protein, eIF4E. EMBO J 19: 3142-3156
    • (2000) EMBO J , vol.19 , pp. 3142-3156
    • Dostie, J.1    Ferraiuolo, M.2    Pause, A.3    Adam, S.A.4    Sonenberg, N.5
  • 11
    • 0032834055 scopus 로고    scopus 로고
    • eIF4 initiation factors: Effectors of mRNA recruitment to ribosomes and regulators of translation
    • Gingras AC, Raught B, Sonenberg N (1999) eIF4 initiation factors: effectors of mRNA recruitment to ribosomes and regulators of translation. Anna Rev Biochem 68: 913-963
    • (1999) Anna Rev Biochem , vol.68 , pp. 913-963
    • Gingras, A.C.1    Raught, B.2    Sonenberg, N.3
  • 12
    • 38849180436 scopus 로고    scopus 로고
    • Targeting the eukaryotic translation initiation factor 4E for cancer therapy
    • Graff JR, Konicek BW, Carter JH, Marcusson EG (2008) Targeting the eukaryotic translation initiation factor 4E for cancer therapy Cancer Res 68: 631-634
    • (2008) Cancer Res , vol.68 , pp. 631-634
    • Graff, J.R.1    Konicek, B.W.2    Carter, J.H.3    Marcusson, E.G.4
  • 13
    • 0037273324 scopus 로고    scopus 로고
    • Translational control and metastatic progression: Enhanced activity of the mRNA cap-binding protein eIF-4E selectively enhances translation of metastasis-related mRNAs
    • Graff JR, Zimmer SG (2003) Translational control and metastatic progression: enhanced activity of the mRNA cap-binding protein eIF-4E selectively enhances translation of metastasis-related mRNAs. Clin Exp Metastasis 20: 265-273
    • (2003) Clin Exp Metastasis , vol.20 , pp. 265-273
    • Graff, J.R.1    Zimmer, S.G.2
  • 14
    • 34250735674 scopus 로고    scopus 로고
    • RNA regulons: Coordination of post-transcriptional events
    • Keene JD (2007) RNA regulons: coordination of post-transcriptional events. Nat Rev Genet 8: 533-543
    • (2007) Nat Rev Genet , vol.8 , pp. 533-543
    • Keene, J.D.1
  • 15
    • 23444446940 scopus 로고    scopus 로고
    • Post-transcriptional operons and regu- lons co-ordinating gene expression
    • Keene JD, Lager PJ (2005) Post-transcriptional operons and regu- lons co-ordinating gene expression. Chromosome Res 13: 327-337
    • (2005) Chromosome Res , vol.13 , pp. 327-337
    • Keene, J.D.1    Lager, P.J.2
  • 16
    • 0035965139 scopus 로고    scopus 로고
    • The RING domains of the promyelocytic leukemia protein PML and the arenaviral protein Z repress translation by directly inhibiting translation initiation factor eIF4E
    • Kentsis A, Dwyer EC, Perez JM, Sharma M, Chen A, Pan ZQ, Borden KL (2001) The RING domains of the promyelocytic leukemia protein PML and the arenaviral protein Z repress translation by directly inhibiting translation initiation factor eIF4E. J Mol Biol 312: 609-623
    • (2001) J Mol Biol , vol.312 , pp. 609-623
    • Kentsis, A.1    Dwyer, E.C.2    Perez, J.M.3    Sharma, M.4    Chen, A.5    Pan, Z.Q.6    Borden, K.L.7
  • 17
    • 11144220618 scopus 로고    scopus 로고
    • Ribavirin suppresses eIF4E-mediated oncogenic transformation by physical mimicry of the 7-methyl guanosine mRNA cap
    • Kentsis A, Topisirovic I, Culjkovic B, Shao L, Borden KL (2004) Ribavirin suppresses eIF4E-mediated oncogenic transformation by physical mimicry of the 7-methyl guanosine mRNA cap. Proc Natl Acad Sci USA 101: 18105-18110
    • (2004) Proc Natl Acad Sci USA , vol.101 , pp. 18105-18110
    • Kentsis, A.1    Topisirovic, I.2    Culjkovic, B.3    Shao, L.4    Borden, K.L.5
  • 18
    • 0026723117 scopus 로고
    • mRNAs containing extensive secondary structure in their 5' non-coding region translate efficiently in cells overexpressing initiation factor eIF-4E
    • Koromilas AE, Lazaris-Karatzas A, Sonenberg N (1992) mRNAs containing extensive secondary structure in their 5' non-coding region translate efficiently in cells overexpressing initiation factor eIF-4E. EMBO J 11: 4153-4158
    • (1992) EMBO J , vol.11 , pp. 4153-4158
    • Koromilas, A.E.1    Lazaris-Karatzas, A.2    Sonenberg, N.3
  • 19
    • 55549107531 scopus 로고    scopus 로고
    • The DEAD-box RNA helicase DDX3 associates with export messenger ribonucleoproteins as well as tip-associated protein and participates in translational control
    • Lai MC, Lee YH, Tarn WY (2008) The DEAD-box RNA helicase DDX3 associates with export messenger ribonucleoproteins as well as tip-associated protein and participates in translational control. Mol Biol Cell 19: 3847-3858
    • (2008) Mol Biol Cell , vol.19 , pp. 3847-3858
    • Lai, M.C.1    Lee, Y.H.2    Tarn, W.Y.3
  • 21
    • 0037774459 scopus 로고    scopus 로고
    • LRP130, a pentatricopeptide motif protein with a noncanonical RNA-binding domain, is bound in vivo to mitochondrial and nuclear RNAs
    • Mili S, Pinol-Roma S (2003) LRP130, a pentatricopeptide motif protein with a noncanonical RNA-binding domain, is bound in vivo to mitochondrial and nuclear RNAs. Mol Cell Biol 23: 4972-4982
    • (2003) Mol Cell Biol , vol.23 , pp. 4972-4982
    • Mili, S.1    Pinol-Roma, S.2
  • 22
    • 0034791334 scopus 로고    scopus 로고
    • Distinct RNP complexes of shuttling hnRNP proteins with pre-mRNA and mRNA: Candi- date intermediates in formation and export of mRNA
    • Mili S, Shu HJ, Zhao Y Pinol-Roma S (2001) Distinct RNP complexes of shuttling hnRNP proteins with pre-mRNA and mRNA: candi- date intermediates in formation and export of mRNA. Mol Cell Biol 21: 7307-7319
    • (2001) Mol Cell Biol , vol.21 , pp. 7307-7319
    • Mili, S.1    Shu, H.J.2    Zhao, Y.3    Pinol-Roma, S.4
  • 23
    • 7044272280 scopus 로고    scopus 로고
    • Evidence for reassociation of RNA-binding proteins after cell lysis: Implications for the interpretation of immunoprecipitation analyses
    • Mili S, Steitz JA (2004) Evidence for reassociation of RNA-binding proteins after cell lysis: implications for the interpretation of immunoprecipitation analyses. RNA 10: 1692-1694
    • (2004) RNA , vol.10 , pp. 1692-1694
    • Mili, S.1    Steitz, J.A.2
  • 24
    • 14644405512 scopus 로고    scopus 로고
    • Initiation of mRNA translation in oncogenesis: The role of eIF4E
    • Montanaro L, Pandolfi PP (2004) Initiation of mRNA translation in oncogenesis: the role of eIF4E. Cell Cycle 3: 1387-1389
    • (2004) Cell Cycle , vol.3 , pp. 1387-1389
    • Montanaro, L.1    Pandolfi, P.P.2
  • 25
    • 24644502657 scopus 로고    scopus 로고
    • From birth to death: The complex lives of eukaryotic mRNAs
    • Moore MJ (2005) From birth to death: the complex lives of eukaryotic mRNAs. Science 309: 1514-1518
    • (2005) Science , vol.309 , pp. 1514-1518
    • Moore, M.J.1
  • 26
    • 0034646512 scopus 로고    scopus 로고
    • PHAX, a mediator of U snRNA nuclear export whose activity is regulated by phosphorylation
    • Ohno M, Segref A, Bachi A, Wilm M, Mattaj IW (2000) PHAX, a mediator of U snRNA nuclear export whose activity is regulated by phosphorylation. Cell 101: 187-198
    • (2000) Cell , vol.101 , pp. 187-198
    • Ohno, M.1    Segref, A.2    Bachi, A.3    Wilm, M.4    Mattaj, I.W.5
  • 27
    • 0033565233 scopus 로고    scopus 로고
    • Repressor binding to a dorsal regulatory site traps human eIF4E in a high cap-affinity state
    • Ptushkina M, von der Haar T, Karim MM, Hughes JM, McCarthy JE (1999) Repressor binding to a dorsal regulatory site traps human eIF4E in a high cap-affinity state. EMBO J 18: 4068-4075
    • (1999) EMBO J , vol.18 , pp. 4068-4075
    • Ptushkina, M.1    von der Haar, T.2    Karim, M.M.3    Hughes, J.M.4    McCarthy, J.E.5
  • 29
    • 0030041884 scopus 로고    scopus 로고
    • Translation initiation of ornithine decarboxylase and nucleocyto- plasmic transport of cyclin Dl mRNA are increased in cells overexpressing eukaryotic initiation factor 4E
    • Rousseau D, Kaspar R, Rosenwald I, Gehrke L, Sonenberg N (1996) Translation initiation of ornithine decarboxylase and nucleocyto- plasmic transport of cyclin Dl mRNA are increased in cells overexpressing eukaryotic initiation factor 4E. Proc Natl Acad Sci USA 93: 1065-1070
    • (1996) Proc Natl Acad Sci USA , vol.93 , pp. 1065-1070
    • Rousseau, D.1    Kaspar, R.2    Rosenwald, I.3    Gehrke, L.4    Sonenberg, N.5
  • 30
    • 0033965922 scopus 로고    scopus 로고
    • The PPR motif-a TPR-related motif prevalent in plant organellar proteins
    • Small ID, Peeters N (2000) The PPR motif-a TPR-related motif prevalent in plant organellar proteins. Trends Biochem Sci 25: 46-47
    • (2000) Trends Biochem Sci , vol.25 , pp. 46-47
    • Small, I.D.1    Peeters, N.2
  • 31
    • 0032054816 scopus 로고    scopus 로고
    • The mRNA 5' cap-binding protein eIF4E and control of cell growth
    • Sonenberg N, Gingras AC (1998) The mRNA 5' cap-binding protein eIF4E and control of cell growth. Cuπ Opin Cell Biol 10: 268-275
    • (1998) Cuπ Opin Cell Biol , vol.10 , pp. 268-275
    • Sonenberg, N.1    Gingras, A.C.2
  • 32
    • 26244459242 scopus 로고    scopus 로고
    • Regulation of p53 translation and induction after DNA damage by ribosomal protein L26 and nucleolin
    • Takagi M, Absalon MJ, McLure KG, Kastan MB (2005) Regulation of p53 translation and induction after DNA damage by ribosomal protein L26 and nucleolin. Cell 123: 49-63
    • (2005) Cell , vol.123 , pp. 49-63
    • Takagi, M.1    Absalon, M.J.2    McLure, K.G.3    Kastan, M.B.4
  • 33
    • 0036333828 scopus 로고    scopus 로고
    • Gamma interferon and cadmium treatments modulate eukaryotic initiation factor 4E- dependent mRNA transport of cyclin Dl in a PML-dependent manner
    • Topisirovic I, Capili AD, Borden KL (2002) Gamma interferon and cadmium treatments modulate eukaryotic initiation factor 4E- dependent mRNA transport of cyclin Dl in a PML-dependent manner. Mol Cell Biol 22: 6183-6198
    • (2002) Mol Cell Biol , vol.22 , pp. 6183-6198
    • Topisirovic, I.1    Capili, A.D.2    Borden, K.L.3
  • 34
    • 0037415692 scopus 로고    scopus 로고
    • The proline-rich homeodomain protein, PRH, is a tissue-specific inhibitor of eIF4E-dependent cyclin Dl mRNA transport and growth
    • Topisirovic I, Culjkovic B, Cohen N, Perez JM, Skrabanek L, Borden KL (2003 a) The proline-rich homeodomain protein, PRH, is a tissue-specific inhibitor of eIF4E-dependent cyclin Dl mRNA transport and growth. EMBO J 22: 689-703
    • (2003) EMBO J , vol.22 , pp. 689-703
    • Topisirovic, I.1    Culjkovic, B.2    Cohen, N.3    Perez, J.M.4    Skrabanek, L.5    Borden, K.L.6
  • 35
    • 0344629665 scopus 로고    scopus 로고
    • Aberrant eukaryotic translation initiation factor 4E-dependent mRNA transport im- pedes hematopoietic differentiation and contributes to leukemo- genesis
    • Topisirovic I, Guzman ML, McConnell MJ, Licht JD, Culjkovic B, Neering SJ, Jordan CT, Borden KL (2003b) Aberrant eukaryotic translation initiation factor 4E-dependent mRNA transport im- pedes hematopoietic differentiation and contributes to leukemo- genesis. Mol Cell Biol 23: 8992-9002
    • (2003) Mol Cell Biol , vol.23 , pp. 8992-9002
    • Topisirovic, I.1    Guzman, M.L.2    McConnell, M.J.3    Licht, J.D.4    Culjkovic, B.5    Neering, S.J.6    Jordan, C.T.7    Borden, K.L.8
  • 36
    • 1842740218 scopus 로고    scopus 로고
    • LRP130, a single-stranded DNA/RNA-bind- ing protein, localizes at the outer nuclear and endoplasmic reticulum membrane, and interacts with mRNA in vivo
    • Tsuchiya N, Fukuda H, Nakashima K, Nagao M, Sugimura T, Nakagama H (2004) LRP130, a single-stranded DNA/RNA-bind- ing protein, localizes at the outer nuclear and endoplasmic reticulum membrane, and interacts with mRNA in vivo. Biochem Biophys Res Commun 317: 736-743
    • (2004) Biochem Biophys Res Commun , vol.317 , pp. 736-743
    • Tsuchiya, N.1    Fukuda, H.2    Nakashima, K.3    Nagao, M.4    Sugimura, T.5    Nakagama, H.6
  • 37
    • 7044253474 scopus 로고    scopus 로고
    • Requirement of DDX3 DEAD box RNA helicase for HIV-1 Rev-RRE export function
    • Yedavalli VS, Neuveut C, Chi YH, Kleiman L, Jeang KT (2004) Requirement of DDX3 DEAD box RNA helicase for HIV-1 Rev-RRE export function. Cell 119: 381-392
    • (2004) Cell , vol.119 , pp. 381-392
    • Yedavalli, V.S.1    Neuveut, C.2    Chi, Y.H.3    Kleiman, L.4    Jeang, K.T.5


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.