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Volumn 8, Issue 5, 2013, Pages

Retraction: IKBKE Phosphorylation and Inhibition of FOXO3a: A Mechanism of IKBKE Oncogenic Function (PLoS ONE (2013) 8:5 (e63636) DOI: 10.1371/journal.pone.0063636);IKBKE Phosphorylation and Inhibition of FOXO3a: A Mechanism of IKBKE Oncogenic Function

Author keywords

[No Author keywords available]

Indexed keywords

I KAPPA B KINASE EPSILON; SERINE; TRANSCRIPTION FACTOR FKHRL1;

EID: 84877745840     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0289330     Document Type: Erratum
Times cited : (41)

References (42)
  • 1
    • 0033623848 scopus 로고    scopus 로고
    • IKKepsilon is part of a novel PMA-inducible IkappaB kinase complex
    • Peters RT, Liao SM, Maniatis T, (2000) IKKepsilon is part of a novel PMA-inducible IkappaB kinase complex. Molecular cell 5: 513-522.
    • (2000) Molecular Cell , vol.5 , pp. 513-522
    • Peters, R.T.1    Liao, S.M.2    Maniatis, T.3
  • 2
    • 33644820252 scopus 로고    scopus 로고
    • Characterization of a novel PMA-inducible pathway of interleukin-13 gene expression in T cells
    • Keen JC, Cianferoni A, Florio G, Guo J, Chen R, et al. (2006) Characterization of a novel PMA-inducible pathway of interleukin-13 gene expression in T cells. Immunology 117: 29-37.
    • (2006) Immunology , vol.117 , pp. 29-37
    • Keen, J.C.1    Cianferoni, A.2    Florio, G.3    Guo, J.4    Chen, R.5
  • 3
    • 0032588170 scopus 로고    scopus 로고
    • NF-kappaB function in growth control: regulation of cyclin D1 expression and G0/G1-to-S-phase transition
    • Hinz M, Krappmann D, Eichten A, Heder A, Scheidereit C, et al. (1999) NF-kappaB function in growth control: regulation of cyclin D1 expression and G0/G1-to-S-phase transition. Mol Cell Biol 19: 2690-2698.
    • (1999) Mol Cell Biol , vol.19 , pp. 2690-2698
    • Hinz, M.1    Krappmann, D.2    Eichten, A.3    Heder, A.4    Scheidereit, C.5
  • 4
    • 0037198274 scopus 로고    scopus 로고
    • NF-kappaB activates Bcl-2 expression in t(14;18) lymphoma cells
    • Heckman CA, Mehew JW, Boxer LM, (2002) NF-kappaB activates Bcl-2 expression in t(14;18) lymphoma cells. Oncogene 21: 3898-3908.
    • (2002) Oncogene , vol.21 , pp. 3898-3908
    • Heckman, C.A.1    Mehew, J.W.2    Boxer, L.M.3
  • 5
    • 79951517699 scopus 로고    scopus 로고
    • Emerging roles for the non-canonical IKKs in cancer
    • Shen RR, Hahn WC, (2011) Emerging roles for the non-canonical IKKs in cancer. Oncogene 30: 631-641.
    • (2011) Oncogene , vol.30 , pp. 631-641
    • Shen, R.R.1    Hahn, W.C.2
  • 6
    • 0035135841 scopus 로고    scopus 로고
    • Protein kinase SGK mediates survival signals by phosphorylating the forkhead transcription factor FKHRL1 (FOXO3a)
    • Brunet A, Park J, Tran H, Hu LS, Hemmings BA, et al. (2001) Protein kinase SGK mediates survival signals by phosphorylating the forkhead transcription factor FKHRL1 (FOXO3a). Mol Cell Biol 21: 952-965.
    • (2001) Mol Cell Biol , vol.21 , pp. 952-965
    • Brunet, A.1    Park, J.2    Tran, H.3    Hu, L.S.4    Hemmings, B.A.5
  • 7
    • 65649114699 scopus 로고    scopus 로고
    • Phosphorylation of the tumor suppressor CYLD by the breast cancer oncogene IKKepsilon promotes cell transformation
    • Hutti JE, Shen RR, Abbott DW, Zhou AY, Sprott KM, et al. (2009) Phosphorylation of the tumor suppressor CYLD by the breast cancer oncogene IKKepsilon promotes cell transformation. Mol Cell 34: 461-472.
    • (2009) Mol Cell , vol.34 , pp. 461-472
    • Hutti, J.E.1    Shen, R.R.2    Abbott, D.W.3    Zhou, A.Y.4    Sprott, K.M.5
  • 8
    • 0042467558 scopus 로고    scopus 로고
    • CYLD is a deubiquitinating enzyme that negatively regulates NF-kappaB activation by TNFR family members
    • Trompouki E, Hatzivassiliou E, Tsichritzis T, Farmer H, Ashworth A, et al. (2003) CYLD is a deubiquitinating enzyme that negatively regulates NF-kappaB activation by TNFR family members. Nature 424: 793-796.
    • (2003) Nature , vol.424 , pp. 793-796
    • Trompouki, E.1    Hatzivassiliou, E.2    Tsichritzis, T.3    Farmer, H.4    Ashworth, A.5
  • 9
    • 28844460239 scopus 로고    scopus 로고
    • The tumor suppressor cylindromatosis (CYLD) acts as a negative regulator for toll-like receptor 2 signaling via negative cross-talk with TRAF6 AND TRAF7
    • Yoshida H, Jono H, Kai H, Li JD, (2005) The tumor suppressor cylindromatosis (CYLD) acts as a negative regulator for toll-like receptor 2 signaling via negative cross-talk with TRAF6 AND TRAF7. The Journal of biological chemistry 280: 41111-41121.
    • (2005) The Journal of Biological Chemistry , vol.280 , pp. 41111-41121
    • Yoshida, H.1    Jono, H.2    Kai, H.3    Li, J.D.4
  • 10
    • 0041967054 scopus 로고    scopus 로고
    • The tumour suppressor CYLD negatively regulates NF-kappaB signalling by deubiquitination
    • Kovalenko A, Chable-Bessia C, Cantarella G, Israel A, Wallach D, et al. (2003) The tumour suppressor CYLD negatively regulates NF-kappaB signalling by deubiquitination. Nature 424: 801-805.
    • (2003) Nature , vol.424 , pp. 801-805
    • Kovalenko, A.1    Chable-Bessia, C.2    Cantarella, G.3    Israel, A.4    Wallach, D.5
  • 11
    • 33847687659 scopus 로고    scopus 로고
    • Multiple functions of the IKK-related kinase IKKepsilon in interferon-mediated antiviral immunity
    • Tenoever BR, Ng SL, Chua MA, McWhirter SM, Garcia-Sastre A, et al. (2007) Multiple functions of the IKK-related kinase IKKepsilon in interferon-mediated antiviral immunity. Science 315: 1274-1278.
    • (2007) Science , vol.315 , pp. 1274-1278
    • Tenoever, B.R.1    Ng, S.L.2    Chua, M.A.3    McWhirter, S.M.4    Garcia-Sastre, A.5
  • 12
    • 33746949870 scopus 로고    scopus 로고
    • Nuclear accumulation of cRel following C-terminal phosphorylation by TBK1/IKK epsilon
    • Harris J, Oliere S, Sharma S, Sun Q, Lin R, et al. (2006) Nuclear accumulation of cRel following C-terminal phosphorylation by TBK1/IKK epsilon. Journal of immunology 177: 2527-2535.
    • (2006) Journal of Immunology , vol.177 , pp. 2527-2535
    • Harris, J.1    Oliere, S.2    Sharma, S.3    Sun, Q.4    Lin, R.5
  • 13
    • 0038393016 scopus 로고    scopus 로고
    • IKKepsilon and TBK1 are essential components of the IRF3 signaling pathway
    • Fitzgerald KA, McWhirter SM, Faia KL, Rowe DC, Latz E, et al. (2003) IKKepsilon and TBK1 are essential components of the IRF3 signaling pathway. Nat Immunol 4: 491-496.
    • (2003) Nat Immunol , vol.4 , pp. 491-496
    • Fitzgerald, K.A.1    McWhirter, S.M.2    Faia, K.L.3    Rowe, D.C.4    Latz, E.5
  • 14
    • 33748756170 scopus 로고    scopus 로고
    • IKK-i/IKKepsilon controls constitutive, cancer cell-associated NF-kappaB activity via regulation of Ser-536 p65/RelA phosphorylation
    • Adli M, Baldwin AS, (2006) IKK-i/IKKepsilon controls constitutive, cancer cell-associated NF-kappaB activity via regulation of Ser-536 p65/RelA phosphorylation. The Journal of biological chemistry 281: 26976-26984.
    • (2006) The Journal of Biological Chemistry , vol.281 , pp. 26976-26984
    • Adli, M.1    Baldwin, A.S.2
  • 15
    • 80054804471 scopus 로고    scopus 로고
    • IKBKE protein activates Akt independent of phosphatidylinositol 3-kinase/PDK1/mTORC2 and the pleckstrin homology domain to sustain malignant transformation
    • Guo JP, Coppola D, Cheng JQ, (2011) IKBKE protein activates Akt independent of phosphatidylinositol 3-kinase/PDK1/mTORC2 and the pleckstrin homology domain to sustain malignant transformation. The Journal of biological chemistry 286: 37389-37398.
    • (2011) The Journal of Biological Chemistry , vol.286 , pp. 37389-37398
    • Guo, J.P.1    Coppola, D.2    Cheng, J.Q.3
  • 17
    • 34249993765 scopus 로고    scopus 로고
    • Integrative genomic approaches identify IKBKE as a breast cancer oncogene
    • Boehm JS, Zhao JJ, Yao J, Kim SY, Firestein R, et al. (2007) Integrative genomic approaches identify IKBKE as a breast cancer oncogene. Cell 129: 1065-1079.
    • (2007) Cell , vol.129 , pp. 1065-1079
    • Boehm, J.S.1    Zhao, J.J.2    Yao, J.3    Kim, S.Y.4    Firestein, R.5
  • 18
    • 67649969188 scopus 로고    scopus 로고
    • Deregulation of IKBKE is associated with tumor progression, poor prognosis, and cisplatin resistance in ovarian cancer
    • Guo JP, Shu SK, He L, Lee YC, Kruk PA, et al. (2009) Deregulation of IKBKE is associated with tumor progression, poor prognosis, and cisplatin resistance in ovarian cancer. Am J Pathol 175: 324-333.
    • (2009) Am J Pathol , vol.175 , pp. 324-333
    • Guo, J.P.1    Shu, S.K.2    He, L.3    Lee, Y.C.4    Kruk, P.A.5
  • 19
    • 33749346063 scopus 로고    scopus 로고
    • Ionizing radiation activates expression of FOXO3a, Fas ligand, and Bim, and induces cell apoptosis
    • Yang JY, Xia W, Hu MC, (2006) Ionizing radiation activates expression of FOXO3a, Fas ligand, and Bim, and induces cell apoptosis. Int J Oncol 29: 643-648.
    • (2006) Int J Oncol , vol.29 , pp. 643-648
    • Yang, J.Y.1    Xia, W.2    Hu, M.C.3
  • 21
    • 0034459180 scopus 로고    scopus 로고
    • Forkhead transcription factor FKHR-L1 modulates cytokine-dependent transcriptional regulation of p27(KIP1)
    • Dijkers PF, Medema RH, Pals C, Banerji L, Thomas NS, et al. (2000) Forkhead transcription factor FKHR-L1 modulates cytokine-dependent transcriptional regulation of p27(KIP1). Mol Cell Biol 20: 9138-9148.
    • (2000) Mol Cell Biol , vol.20 , pp. 9138-9148
    • Dijkers, P.F.1    Medema, R.H.2    Pals, C.3    Banerji, L.4    Thomas, N.S.5
  • 22
    • 0036839685 scopus 로고    scopus 로고
    • Cell cycle inhibition by FoxO forkhead transcription factors involves downregulation of cyclin D
    • Schmidt M, Fernandez de Mattos S, van der Horst A, Klompmaker R, Kops GJ, et al. (2002) Cell cycle inhibition by FoxO forkhead transcription factors involves downregulation of cyclin D. Mol Cell Biol. 22: 7842-7852.
    • (2002) Mol Cell Biol , vol.22 , pp. 7842-7852
    • Schmidt, M.1    Fernandez de Mattos, S.2    van der Horst, A.3    Klompmaker, R.4    Kops, G.J.5
  • 23
    • 0037134040 scopus 로고    scopus 로고
    • DNA repair pathway stimulated by the forkhead transcription factor FOXO3a through the Gadd45 protein
    • Tran H, Brunet A, Grenier JM, Datta SR, Fornace AJ Jr, et al. (2002) DNA repair pathway stimulated by the forkhead transcription factor FOXO3a through the Gadd45 protein. Science 296: 530-534.
    • (2002) Science , vol.296 , pp. 530-534
    • Tran, H.1    Brunet, A.2    Grenier, J.M.3    Datta, S.R.4    Fornace Jr., A.J.5
  • 25
    • 33751547223 scopus 로고    scopus 로고
    • Correlation between FOXO1a (FKHR) and FOXO3a (FKHRL1) binding and the inhibition of basal glucose-6-phosphatase catalytic subunit gene transcription by insulin
    • Onuma H, Vander Kooi BT, Boustead JN, Oeser JK, O'Brien RM, (2006) Correlation between FOXO1a (FKHR) and FOXO3a (FKHRL1) binding and the inhibition of basal glucose-6-phosphatase catalytic subunit gene transcription by insulin. Mol Endocrinol 20: 2831-2847.
    • (2006) Mol Endocrinol , vol.20 , pp. 2831-2847
    • Onuma, H.1    Vander Kooi, B.T.2    Boustead, J.N.3    Oeser, J.K.4    O'Brien, R.M.5
  • 26
    • 11144357466 scopus 로고    scopus 로고
    • IkappaB kinase promotes tumorigenesis through inhibition of forkhead FOXO3a
    • Hu MC, Lee DF, Xia W, Golfman LS, Ou-Yang F, et al. (2004) IkappaB kinase promotes tumorigenesis through inhibition of forkhead FOXO3a. Cell 117: 225-237.
    • (2004) Cell , vol.117 , pp. 225-237
    • Hu, M.C.1    Lee, D.F.2    Xia, W.3    Golfman, L.S.4    Ou-Yang, F.5
  • 27
    • 34447626095 scopus 로고    scopus 로고
    • SIRT2 deacetylates FOXO3a in response to oxidative stress and caloric restriction
    • Wang F, Nguyen M, Qin FX, Tong Q, (2007) SIRT2 deacetylates FOXO3a in response to oxidative stress and caloric restriction. Aging Cell 6: 505-514.
    • (2007) Aging Cell , vol.6 , pp. 505-514
    • Wang, F.1    Nguyen, M.2    Qin, F.X.3    Tong, Q.4
  • 28
    • 1642580499 scopus 로고    scopus 로고
    • FoxO3a regulates erythroid differentiation and induces BTG1, an activator of protein arginine methyl transferase 1
    • Bakker WJ, Blazquez-Domingo M, Kolbus A, Besooyen J, Steinlein P, et al. (2004) FoxO3a regulates erythroid differentiation and induces BTG1, an activator of protein arginine methyl transferase 1. J Cell Biol 164: 175-184.
    • (2004) J Cell Biol , vol.164 , pp. 175-184
    • Bakker, W.J.1    Blazquez-Domingo, M.2    Kolbus, A.3    Besooyen, J.4    Steinlein, P.5
  • 29
    • 0033582929 scopus 로고    scopus 로고
    • Akt promotes cell survival by phosphorylating and inhibiting a Forkhead transcription factor
    • Brunet A, Bonni A, Zigmond MJ, Lin MZ, Juo P, et al. (1999) Akt promotes cell survival by phosphorylating and inhibiting a Forkhead transcription factor. Cell 96: 857-868.
    • (1999) Cell , vol.96 , pp. 857-868
    • Brunet, A.1    Bonni, A.2    Zigmond, M.J.3    Lin, M.Z.4    Juo, P.5
  • 30
    • 38849139580 scopus 로고    scopus 로고
    • ERK promotes tumorigenesis by inhibiting FOXO3a via MDM2-mediated degradation
    • Yang JY, Zong CS, Xia W, Yamaguchi H, Ding Q, et al. (2008) ERK promotes tumorigenesis by inhibiting FOXO3a via MDM2-mediated degradation. Nat Cell Biol 10: 138-148.
    • (2008) Nat Cell Biol , vol.10 , pp. 138-148
    • Yang, J.Y.1    Zong, C.S.2    Xia, W.3    Yamaguchi, H.4    Ding, Q.5
  • 31
    • 78549243034 scopus 로고    scopus 로고
    • IkappaB kinase overcomes PI3K/Akt and ERK/MAPK to control FOXO3a activity in acute myeloid leukemia
    • Chapuis N, Park S, Leotoing L, Tamburini J, Verdier F, et al. (2010) IkappaB kinase overcomes PI3K/Akt and ERK/MAPK to control FOXO3a activity in acute myeloid leukemia. Blood 116: 4240-4250.
    • (2010) Blood , vol.116 , pp. 4240-4250
    • Chapuis, N.1    Park, S.2    Leotoing, L.3    Tamburini, J.4    Verdier, F.5
  • 32
    • 0030611595 scopus 로고    scopus 로고
    • IkappaB kinase-beta: NF-kappaB activation and complex formation with IkappaB kinase-alpha and NIK
    • Woronicz JD, Gao X, Cao Z, Rothe M, Goeddel DV, (1997) IkappaB kinase-beta: NF-kappaB activation and complex formation with IkappaB kinase-alpha and NIK. Science 278: 866-869.
    • (1997) Science , vol.278 , pp. 866-869
    • Woronicz, J.D.1    Gao, X.2    Cao, Z.3    Rothe, M.4    Goeddel, D.V.5
  • 33
    • 0035881568 scopus 로고    scopus 로고
    • Phosphatidylinositol-3-OH Kinase (PI3K)/AKT2, activated in breast cancer, regulates and is induced by estrogen receptor alpha (ERalpha) via interaction between ERalpha and PI3K
    • Sun M, Paciga JE, Feldman RI, Yuan Z, Coppola D, et al. (2001) Phosphatidylinositol-3-OH Kinase (PI3K)/AKT2, activated in breast cancer, regulates and is induced by estrogen receptor alpha (ERalpha) via interaction between ERalpha and PI3K. Cancer Res 61: 5985-5991.
    • (2001) Cancer Res , vol.61 , pp. 5985-5991
    • Sun, M.1    Paciga, J.E.2    Feldman, R.I.3    Yuan, Z.4    Coppola, D.5
  • 34
    • 34249058290 scopus 로고    scopus 로고
    • Modulation of the interferon antiviral response by the TBK1/IKKi adaptor protein TANK
    • Guo B, Cheng G, (2007) Modulation of the interferon antiviral response by the TBK1/IKKi adaptor protein TANK. J Biol Chem 282: 11817-11826.
    • (2007) J Biol Chem , vol.282 , pp. 11817-11826
    • Guo, B.1    Cheng, G.2
  • 35
    • 35548930209 scopus 로고    scopus 로고
    • The emerging roles of forkhead box (Fox) proteins in cancer
    • Myatt SS, Lam EW, (2007) The emerging roles of forkhead box (Fox) proteins in cancer. Nat Rev Cancer 7: 847-859.
    • (2007) Nat Rev Cancer , vol.7 , pp. 847-859
    • Myatt, S.S.1    Lam, E.W.2
  • 36
    • 84872201790 scopus 로고    scopus 로고
    • IKBKE is induced by STAT3 and tobacco carcinogen and determines chemosensitivity in non-small cell lung cancer
    • Guo J, Kim D, Gao J, Kurtyka C, Chen H, et al. (2013) IKBKE is induced by STAT3 and tobacco carcinogen and determines chemosensitivity in non-small cell lung cancer. Oncogene 10 32: 151-9.
    • (2013) Oncogene 10 , vol.32 , pp. 151-159
    • Guo, J.1    Kim, D.2    Gao, J.3    Kurtyka, C.4    Chen, H.5
  • 37
    • 0037136563 scopus 로고    scopus 로고
    • Forkhead transcription factor FOXO3a protects quiescent cells from oxidative stress
    • Kops GJ, Dansen TB, Polderman PE, Saarloos I, Wirtz KW, et al. (2002) Forkhead transcription factor FOXO3a protects quiescent cells from oxidative stress. Nature 419: 316-321.
    • (2002) Nature , vol.419 , pp. 316-321
    • Kops, G.J.1    Dansen, T.B.2    Polderman, P.E.3    Saarloos, I.4    Wirtz, K.W.5
  • 38
    • 77953208940 scopus 로고    scopus 로고
    • Foxo3a expression and acetylation regulate cancer cell growth and sensitivity to cisplatin
    • Shiota M, Yokomizo A, Kashiwagi E, Tada Y, Inokuchi J, et al. (2010) Foxo3a expression and acetylation regulate cancer cell growth and sensitivity to cisplatin. Cancer Sci 101: 1177-1185.
    • (2010) Cancer Sci , vol.101 , pp. 1177-1185
    • Shiota, M.1    Yokomizo, A.2    Kashiwagi, E.3    Tada, Y.4    Inokuchi, J.5
  • 39
    • 77952373274 scopus 로고    scopus 로고
    • FOXO3a regulates glycolysis via transcriptional control of tumor suppressor TSC1
    • Khatri S, Yepiskoposyan H, Gallo CA, Tandon P, Plas DR, (2010) FOXO3a regulates glycolysis via transcriptional control of tumor suppressor TSC1. J Biol Chem 285: 15960-15965.
    • (2010) J Biol Chem , vol.285 , pp. 15960-15965
    • Khatri, S.1    Yepiskoposyan, H.2    Gallo, C.A.3    Tandon, P.4    Plas, D.R.5
  • 40
    • 0037134530 scopus 로고    scopus 로고
    • IKK-i and TBK-1 are enzymatically distinct from the homologous enzyme IKK-2: comparative analysis of recombinant human IKK-i, TBK-1, and IKK-2
    • Kishore N, Huynh QK, Mathialagan S, Hall T, Rouw S, et al. (2002) IKK-i and TBK-1 are enzymatically distinct from the homologous enzyme IKK-2: comparative analysis of recombinant human IKK-i, TBK-1, and IKK-2. J Biol Chem 277: 13840-13847.
    • (2002) J Biol Chem , vol.277 , pp. 13840-13847
    • Kishore, N.1    Huynh, Q.K.2    Mathialagan, S.3    Hall, T.4    Rouw, S.5
  • 41
    • 84859023600 scopus 로고    scopus 로고
    • p85alpha SH2 domain phosphorylation by IKK promotes feedback inhibition of PI3K and Akt in response to cellular starvation
    • Comb WC, Hutti JE, Cogswell P, Cantley LC, Baldwin AS, (2012) p85alpha SH2 domain phosphorylation by IKK promotes feedback inhibition of PI3K and Akt in response to cellular starvation. Mol Cell 45: 719-730.
    • (2012) Mol Cell , vol.45 , pp. 719-730
    • Comb, W.C.1    Hutti, J.E.2    Cogswell, P.3    Cantley, L.C.4    Baldwin, A.S.5
  • 42
    • 84860247259 scopus 로고    scopus 로고
    • FOXO3 as a new IKK-epsilon-controlled check-point of regulation of IFN-beta expression
    • Luron L, Saliba D, Blazek K, Lanfrancotti A, Udalova IA, (2012) FOXO3 as a new IKK-epsilon-controlled check-point of regulation of IFN-beta expression. Eur J Immunol 42: 1030-1037.
    • (2012) Eur J Immunol , vol.42 , pp. 1030-1037
    • Luron, L.1    Saliba, D.2    Blazek, K.3    Lanfrancotti, A.4    Udalova, I.A.5


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