Accumulation of long-chain glycosphingolipids during aging is prevented by caloric restriction

PLoS ONE

Volumn 6, Issue 6, 2011, Pages

  Hernández Corbacho, María José ^a   Jenkins, Russell W ^a   Clarke, Christopher J ^a   Hannun, Yusuf A ^a   Obeid, Lina M ^a,b   Snider, Ashley J ^a,b   Siskind, Leah J ^a,b  

^a MEDICAL UNIVERSITY OF SOUTH CAROLINA   (United States)

^b RALPH H JOHNSON VA MEDICAL CENTER   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CERAMIDE; CERAMIDE HEXOSIDE; CERAMIDE SYNTHASE; GLYCOSPHINGOLIPID; LACTOSYLCERAMIDE; SPHINGOLIPID; SPHINGOMYELIN PHOSPHODIESTERASE; SYNTHETASE; UNCLASSIFIED DRUG; DIHYDROCERAMIDE DESATURASE; OXIDOREDUCTASE;

AGED; AGING; ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; BRAIN TISSUE; CALORIC RESTRICTION; CONTROLLED STUDY; ENZYME SYNTHESIS; FEMALE; FIBROBLAST; HUMAN; HUMAN CELL; KIDNEY DYSFUNCTION; KIDNEY PARENCHYMA; LIPID ANALYSIS; LIPID METABOLISM; LIPID STORAGE; LIVER PARENCHYMA; MALE; MOUSE; NONHUMAN; ADULT; ANIMAL; ANTIBODY SPECIFICITY; C57BL MOUSE; CHEMISTRY; METABOLISM; MIDDLE AGED; PHYSIOLOGY;

MAMMALIA; MUS; RODENTIA; SPHINGOIDEA;

AGED, 80 AND OVER; AGING; ANIMALS; CALORIC RESTRICTION; CERAMIDES; FEMALE; FIBROBLASTS; GLYCOSPHINGOLIPIDS; HUMANS; MALE; MICE; MICE, INBRED C57BL; MIDDLE AGED; ORGAN SPECIFICITY; OXIDOREDUCTASES; SPHINGOMYELIN PHOSPHODIESTERASE; YOUNG ADULT;

EID: 79958095013     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0020411     Document Type: Article

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