-
1
-
-
78649496901
-
-
Fleming F. F, Yao L. H, Ravikumar P. C, Funk L, Shook B. C. J. Med. Chem. 2010 53 7902.
-
(2010)
J. Med. Chem.
, vol.53
, pp. 7902
-
-
Fleming, F.F.1
Yao, L.H.2
Ravikumar, P.C.3
Funk, L.4
Shook, B.C.5
-
2
-
-
22744449063
-
-
Augeri D. J, Robl J. A, Betebenner D. A, Magnin D. R, Khanna A, Robertson J. G, Wang A, Simpkins L. M, Taunk P, Huang Q, Han S. P, Abboa-Offei B, Cap M, Xin L, Tao L, Tozzo E, Welzel G. E, Egan D. M, Marcinkeviciene J, Chang S. Y, Biller S. A, Kirby M. S, Parker R. A, Hamann L. G. J. Med. Chem. 2005 48 5025.
-
(2005)
J. Med. Chem.
, vol.48
, pp. 5025
-
-
Augeri, D.J.1
Robl, J.A.2
Betebenner, D.A.3
Magnin, D.R.4
Khanna, A.5
Robertson, J.G.6
Wang, A.7
Simpkins, L.M.8
Taunk, P.9
Huang, Q.10
Han, S.P.11
Abboa-Offei, B.12
Cap, M.13
Xin, L.14
Tao, L.15
Tozzo, E.16
Welzel, G.E.17
Egan, D.M.18
Marcinkeviciene, J.19
Chang, S.Y.20
Biller, S.A.21
Kirby, M.S.22
Parker, R.A.23
Hamann, L.G.24
more..
-
4
-
-
28544432675
-
-
Teodori E, Dei S, Garnier-Suillerot A, Gualtieri F, Manetti D, Martelli C, Romanelli M. N, Scapecchi S, Sudwan P, Salerno M. J. Med. Chem. 2005 48 7426.
-
(2005)
J. Med. Chem.
, vol.48
, pp. 7426
-
-
Teodori, E.1
Dei, S.2
Garnier-Suillerot, A.3
Gualtieri, F.4
Manetti, D.5
Martelli, C.6
Romanelli, M.N.7
Scapecchi, S.8
Sudwan, P.9
Salerno, M.10
-
10
-
-
0034609805
-
-
Hunt J. T, Ding C. Z, Batorsky R, Bednarz M, Bhide R, Cho Y, Chong S, Chao S, Gullo-Brown J, Guo P, Kim S. K, Lee F. Y. F, Leftheris K, Miller A, Mitt T, Patel M, Penhallow B. A, Ricca C, Rose W. C, Schmidt R. C, Slusarchyk W. A, Vite G, Manne V. J. Med. Chem. 2000 43 3587.
-
(2000)
J. Med. Chem.
, vol.43
, pp. 3587
-
-
Hunt, J.T.1
Ding, C.Z.2
Batorsky, R.3
Bednarz, M.4
Bhide, R.5
Cho, Y.6
Chong, S.7
Chao, S.8
Gullo-Brown, J.9
Guo, P.10
Kim, S.K.11
Lee, F.Y.F.12
Leftheris, K.13
Miller, A.14
Mitt, T.15
Patel, M.16
Penhallow, B.A.17
Ricca, C.18
Rose, W.C.19
Schmidt, R.C.20
Slusarchyk, W.A.21
Vite, G.22
Manne, V.23
more..
-
12
-
-
0034710707
-
-
Wissner A, Berger D. M, Boschelli D. H, Floyd J. B, Greenberger L. M, Gruber B. C, Johnson B. D, Mamuya N, Nilakantan R, Reich M. F, Shen R, Tsou H, Upelacis E, Wang Y. F, Wu B, Ye F, Zhang N. J. Med. Chem. 2000 43 3244.
-
(2000)
J. Med. Chem.
, vol.43
, pp. 3244
-
-
Wissner, A.1
Berger, D.M.2
Boschelli, D.H.3
Floyd, J.B.4
Greenberger, L.M.5
Gruber, B.C.6
Johnson, B.D.7
Mamuya, N.8
Nilakantan, R.9
Reich, M.F.10
Shen, R.11
Tsou, H.12
Upelacis, E.13
Wang, Y.F.14
Wu, B.15
Ye, F.16
Zhang, N.17
-
13
-
-
2542582261
-
-
Rabindran S. K, Discafani C. M, Rosfjord E. C, Baxter M, Floyd M. B, Golas J, Hallett W. A, Johnson B. D, Nilakantan R, Overbeek E, Reich M. F, Shen R, Shi X, Tsou H. R, Wang Y. F, Wissner A. Cancer Res. 2004 64 3958.
-
(2004)
Cancer Res.
, vol.64
, pp. 3958
-
-
Rabindran, S.K.1
Discafani, C.M.2
Rosfjord, E.C.3
Baxter, M.4
Floyd, M.B.5
Golas, J.6
Hallett, W.A.7
Johnson, B.D.8
Nilakantan, R.9
Overbeek, E.10
Reich, M.F.11
Shen, R.12
Shi, X.13
Tsou, H.R.14
Wang, Y.F.15
Wissner, A.16
-
14
-
-
79952191279
-
-
Lee Y. J, Kim J. H, Kim S. K, Ha S. J, Mok T. S, Mitsudomi T, Cho B. C. Lung Cancer 2011 72 9.
-
(2011)
Lung Cancer
, vol.72
, pp. 9
-
-
Lee, Y.J.1
Kim, J.H.2
Kim, S.K.3
Ha, S.J.4
Mok, T.S.5
Mitsudomi, T.6
Cho, B.C.7
-
16
-
-
33748861075
-
-
Gunby R. H, Ahmed S, Sottocornola R, Gasser M, Redaelli S, Mologni L, Tartari C. J, Belloni V, Gambacorti-Passerini C, Scapozza L. J. Med. Chem. 2006 49 5759.
-
(2006)
J. Med. Chem.
, vol.49
, pp. 5759
-
-
Gunby, R.H.1
Ahmed, S.2
Sottocornola, R.3
Gasser, M.4
Redaelli, S.5
Mologni, L.6
Tartari, C.J.7
Belloni, V.8
Gambacorti-Passerini, C.9
Scapozza, L.10
-
18
-
-
2342620790
-
-
Das K, Clark A. D. Jr, Lewi P. J, Heeres J, De Jonge M. R, Koymans L. M. H, Vinkers H. M, Daeyaert F, Ludovici D. W, Kukla M. J, De Corte B, Kavash R. W, Ho C. Y, Ye H, Lichtenstein M. A, Andries K, Pauwels R, de Béthune M. P, Boyer P. L, Clark P, Hughes S. H, Janssen P. A. J, Arnold E. J. Med. Chem. 2004 47 2550.
-
(2004)
J. Med. Chem.
, vol.47
, pp. 2550
-
-
Das, K.1
Clark Jr., A.D.2
Lewi, P.J.3
Heeres, J.4
De Jonge, M.R.5
Koymans, L.M.H.6
Vinkers, H.M.7
Daeyaert, F.8
Ludovici, D.W.9
Kukla, M.J.10
De Corte, B.11
Kavash, R.W.12
Ho, C.Y.13
Ye, H.14
Lichtenstein, M.A.15
Andries, K.16
Pauwels, R.17
De Béthune, M.P.18
Boyer, P.L.19
Clark, P.20
Hughes, S.H.21
Janssen, P.A.J.22
Arnold, E.23
more..
-
19
-
-
40549106089
-
-
Nuttall J. P, Thake D. C, Lewis M. G, Ferkany J. W, Romano J. W, Mitchnick M. A. Antimicrob. Agents Chemother. 2008 52 909.
-
(2008)
Antimicrob. Agents Chemother.
, vol.52
, pp. 909
-
-
Nuttall, J.P.1
Thake, D.C.2
Lewis, M.G.3
Ferkany, J.W.4
Romano, J.W.5
Mitchnick, M.A.6
-
22
-
-
0037449776
-
-
Okamoto K, Eger B. T, Nishino T, Kondo S, Pai E. F, Nishino T. J. Biol. Chem. 2003 278 1848.
-
(2003)
J. Biol. Chem.
, vol.278
, pp. 1848
-
-
Okamoto, K.1
Eger, B.T.2
Nishino, T.3
Kondo, S.4
Pai, E.F.5
Nishino, T.6
-
23
-
-
71749101438
-
-
Sato T, Ashizawa N, Matsumoto K, Iwanaga T, Nakamura H, Inoue T, Nagata O. Bioorg. Med. Chem. Lett. 2009 19 6225.
-
(2009)
Bioorg. Med. Chem. Lett.
, vol.19
, pp. 6225
-
-
Sato, T.1
Ashizawa, N.2
Matsumoto, K.3
Iwanaga, T.4
Nakamura, H.5
Inoue, T.6
Nagata, O.7
-
24
-
-
2542612969
-
-
Okamoto K, Matsumoto K, Hille R, Eger B. T, Pai E. F, Nishino T. Proc. Natl. Acad. Sci. U. S. A. 2004 101 7931.
-
(2004)
Proc. Natl. Acad. Sci. U. S. A.
, vol.101
, pp. 7931
-
-
Okamoto, K.1
Matsumoto, K.2
Hille, R.3
Eger, B.T.4
Pai, E.F.5
Nishino, T.6
-
25
-
-
35148828100
-
-
Teno N, Miyake T, Ehara T, Irie O, Sakaki J, Ohmori O, Gunji H, Matsuura N, Masuya K, Hitomi Y, Nonomura K, Horiuchi M, Gohda K, Iwasaki A, Umemura I, Tada S, Kometani M, Iwasaki G, Cowan-Jacob S. W, Missbach M, Lattmann R, Betschart C. Bioorg. Med. Chem. Lett. 2007 17 6096.
-
(2007)
Bioorg. Med. Chem. Lett.
, vol.17
, pp. 6096
-
-
Teno, N.1
Miyake, T.2
Ehara, T.3
Irie, O.4
Sakaki, J.5
Ohmori, O.6
Gunji, H.7
Matsuura, N.8
Masuya, K.9
Hitomi, Y.10
Nonomura, K.11
Horiuchi, M.12
Gohda, K.13
Iwasaki, A.14
Umemura, I.15
Tada, S.16
Kometani, M.17
Iwasaki, G.18
Cowan-Jacob, S.W.19
Missbach, M.20
Lattmann, R.21
Betschart, C.22
more..
-
26
-
-
22744449063
-
-
Augeri D. J, Robl J. A, Betebenner D. A, Magnin D. R, Khanna A, Robertson J. G, Wang A, Simpkins L. M, Taunk P, Huang Q, Han S.-P, Abboa-Offei B, Cap M, Xin L, Tao L, Tozzo E, Welzel G. E, Egan D. M, Marcinkeviciene J, Chang S. Y, Biller S. A, Kirby M. S, Parker R. A, Hamann L. G. J. Med. Chem. 2005 48 5025.
-
(2005)
J. Med. Chem.
, vol.48
, pp. 5025
-
-
Augeri, D.J.1
Robl, J.A.2
Betebenner, D.A.3
Magnin, D.R.4
Khanna, A.5
Robertson, J.G.6
Wang, A.7
Simpkins, L.M.8
Taunk, P.9
Huang, Q.10
Han, S.-P.11
Abboa-Offei, B.12
Cap, M.13
Xin, L.14
Tao, L.15
Tozzo, E.16
Welzel, G.E.17
Egan, D.M.18
Marcinkeviciene, J.19
Chang, S.Y.20
Biller, S.A.21
Kirby, M.S.22
Parker, R.A.23
Hamann, L.G.24
more..
-
27
-
-
0037777695
-
-
Villhauer E. B, Brinkman J. A, Naderi G. B, Burkey B. F, Dunning B. E, Prasad K, Mangold B. L, Russel M. E, Hughes T. E. J. Med. Chem. 2003 46 2774.
-
(2003)
J. Med. Chem.
, vol.46
, pp. 2774
-
-
Villhauer, E.B.1
Brinkman, J.A.2
Naderi, G.B.3
Burkey, B.F.4
Dunning, B.E.5
Prasad, K.6
Mangold, B.L.7
Russel, M.E.8
Hughes, T.E.9
-
29
-
-
61449170189
-
-
He H, Tran P, Yin H, Smith H, Batard Y, Wang L, Einolf H, Gu H, Mangold J. B, Fischer V, Howard D. Drug Metab. Dispos. 2009 37 536.
-
(2009)
Drug Metab. Dispos.
, vol.37
, pp. 536
-
-
He, H.1
Tran, P.2
Yin, H.3
Smith, H.4
Batard, Y.5
Wang, L.6
Einolf, H.7
Gu, H.8
Mangold, J.B.9
Fischer, V.10
Howard, D.11
-
30
-
-
73349138608
-
-
Cooper-DeHoff R. M, Handberg E. M, Mancia G, Zhou Q, Champion A, Legler U. F, Pepine C. J. Expert Rev. Cardiovasc. Ther. 2009 7 1329.
-
(2009)
Expert Rev. Cardiovasc. Ther.
, vol.7
, pp. 1329
-
-
Cooper-Dehoff, R.M.1
Handberg, E.M.2
Mancia, G.3
Zhou, Q.4
Champion, A.5
Legler, U.F.6
Pepine, C.J.7
-
32
-
-
14444268769
-
-
Christensen S, Guider A, Forster C. J, Gleason J. G, Bender P. E, Karpinski J. M, Dewolf W. E, Barnette M. S, Underwood D. C, Griswold D. E, Cieslinski L. B, Burman M, Bochnowicz S, Osborn R. R, Manning C. D, Grous M, Hillegas L. M, Bartus J. O, Ryan M. D, Eggleston D. S, Haltiwanger R. C, Torphy T. J. J. Med. Chem. 1998 41 821.
-
(1998)
J. Med. Chem.
, vol.41
, pp. 821
-
-
Christensen, S.1
Guider, A.2
Forster, C.J.3
Gleason, J.G.4
Bender, P.E.5
Karpinski, J.M.6
Dewolf, W.E.7
Barnette, M.S.8
Underwood, D.C.9
Griswold, D.E.10
Cieslinski, L.B.11
Burman, M.12
Bochnowicz, S.13
Osborn, R.R.14
Manning, C.D.15
Grous, M.16
Hillegas, L.M.17
Bartus, J.O.18
Ryan, M.D.19
Eggleston, D.S.20
Haltiwanger, R.C.21
Torphy, T.J.22
more..
-
33
-
-
20844442458
-
-
Card G. L, England B. P, Suzuki Y, Fong D, Powell B, Lee B, Luu C, Tabrizizad M, Gillette S, Ibrahim P. N, Artis D. R, Bollag G, Milburn M. V, Kim S.-H, Schlessinger J, Zhang K. Y. J. Structure 2004 12 2233.
-
(2004)
Structure
, vol.12
, pp. 2233
-
-
Card, G.L.1
England, B.P.2
Suzuki, Y.3
Fong, D.4
Powell, B.5
Lee, B.6
Luu, C.7
Tabrizizad, M.8
Gillette, S.9
Ibrahim, P.N.10
Artis, D.R.11
Bollag, G.12
Milburn, M.V.13
Kim, S.-H.14
Schlessinger, J.15
Zhang, K.Y.J.16
-
34
-
-
67749102047
-
-
Sheng C, Miao Z, Ji H, Yao J, Wang W, Che X, Dong G, Lv J, Guo W, Zhang W. Antimicrob. Agents Chemother. 2009 53 3487.
-
(2009)
Antimicrob. Agents Chemother.
, vol.53
, pp. 3487
-
-
Sheng, C.1
Miao, Z.2
Ji, H.3
Yao, J.4
Wang, W.5
Che, X.6
Dong, G.7
Lv, J.8
Guo, W.9
Zhang, W.10
-
35
-
-
0025970208
-
-
Browne L. J, Gude C, Rodriguez H, Steele R. E, Bhatnager A. J. Med. Chem. 1991 34 725.
-
(1991)
J. Med. Chem.
, vol.34
, pp. 725
-
-
Browne, L.J.1
Gude, C.2
Rodriguez, H.3
Steele, R.E.4
Bhatnager, A.5
-
40
-
-
17844376217
-
-
Bohl C. E, Gao W, Miller D. D, Bell C. E, Dalton J. T. Proc. Natl. Acad. Sci. U. S. A. 2005 102 6201.
-
(2005)
Proc. Natl. Acad. Sci. U. S. A.
, vol.102
, pp. 6201
-
-
Bohl, C.E.1
Gao, W.2
Miller, D.D.3
Bell, C.E.4
Dalton, J.T.5
-
41
-
-
71749096236
-
-
Kern J. C, Terefenko E, Trybulski E, Berrodin T. J, Cohen J, Winneker R. C, Yudt M. R, Zhang Z, Zhu Y, Zhang P. Bioorg. Med. Chem. Lett. 2009 19 6666.
-
(2009)
Bioorg. Med. Chem. Lett.
, vol.19
, pp. 6666
-
-
Kern, J.C.1
Terefenko, E.2
Trybulski, E.3
Berrodin, T.J.4
Cohen, J.5
Winneker, R.C.6
Yudt, M.R.7
Zhang, Z.8
Zhu, Y.9
Zhang, P.10
-
42
-
-
77951130159
-
-
Zhou H. B, Lee J. H, Mayne C. G, Carlson K. E, Katzenellenbogen J. A. J. Med. Chem. 2010 53 3349.
-
(2010)
J. Med. Chem.
, vol.53
, pp. 3349
-
-
Zhou, H.B.1
Lee, J.H.2
Mayne, C.G.3
Carlson, K.E.4
Katzenellenbogen, J.A.5
-
43
-
-
23444440846
-
-
Fensome A, Bender R, Chopra R, Cohen J, Collins M. A, Hudak V, Malakian K, Lockhead S, Olland A, Svenson K, Terefenko E. A, Unwalla R. J, Wilhelm J. M, Wolfrom S, Zhu Y, Zhang Z, Zhang P, Winneker R. C, Wrobel J. J. Med. Chem. 2005 48 5092.
-
(2005)
J. Med. Chem.
, vol.48
, pp. 5092
-
-
Fensome, A.1
Bender, R.2
Chopra, R.3
Cohen, J.4
Collins, M.A.5
Hudak, V.6
Malakian, K.7
Lockhead, S.8
Olland, A.9
Svenson, K.10
Terefenko, E.A.11
Unwalla, R.J.12
Wilhelm, J.M.13
Wolfrom, S.14
Zhu, Y.15
Zhang, Z.16
Zhang, P.17
Winneker, R.C.18
Wrobel, J.19
-
47
-
-
4444353338
-
-
Heinirich T, Böttcher H, Gericke R, Bartoszyk G. D, Anzali S, Seyfried C. A, Greiner H. E, van Amsterdam C. J. Med. Chem. 2004 47 4684.
-
(2004)
J. Med. Chem.
, vol.47
, pp. 4684
-
-
Heinirich, T.1
Böttcher, H.2
Gericke, R.3
Bartoszyk, G.D.4
Anzali, S.5
Seyfried, C.A.6
Greiner, H.E.7
Van Amsterdam, C.8
-
48
-
-
0037137607
-
-
Madsen P, Ling A, Plewe M, Sams C. K, Knudsen L. B, Sidelmann U. G, Ynddal L, Brand C. L, Andersen B, Murphy D, Teng M, Truesdale L, Kiel D, May J, Kuki A, Shi S, Johnson M. D, Teston K. A, Feng J, Lakis J, Anderes K, Gregor V, Lau J. J. Med. Chem. 2002 45 5755.
-
(2002)
J. Med. Chem.
, vol.45
, pp. 5755
-
-
Madsen, P.1
Ling, A.2
Plewe, M.3
Sams, C.K.4
Knudsen, L.B.5
Sidelmann, U.G.6
Ynddal, L.7
Brand, C.L.8
Andersen, B.9
Murphy, D.10
Teng, M.11
Truesdale, L.12
Kiel, D.13
May, J.14
Kuki, A.15
Shi, S.16
Johnson, M.D.17
Teston, K.A.18
Feng, J.19
Lakis, J.20
Anderes, K.21
Gregor, V.22
Lau, J.23
more..
-
49
-
-
69949108856
-
-
Mowbray C. E, Corbau R, Hawes M, Jones L. H, Mills J. E, Perros M, Selby M. D, Stupple P. A, Webster R, Wood A. Bioorg. Med. Chem. Lett. 2009 19 5603.
-
(2009)
Bioorg. Med. Chem. Lett.
, vol.19
, pp. 5603
-
-
Mowbray, C.E.1
Corbau, R.2
Hawes, M.3
Jones, L.H.4
Mills, J.E.5
Perros, M.6
Selby, M.D.7
Stupple, P.A.8
Webster, R.9
Wood, A.10
-
50
-
-
70349214797
-
-
Mowbray C. E; Burt C, Corbau R, Gayton S, Hawes M, Perros M, Tran I, Price D. A; Quinton F. J, Selby M. D, Stupple P. A, Webster R, Wood A. Bioorg. Med. Chem. Lett. 2009 19 5857.
-
(2009)
Bioorg. Med. Chem. Lett.
, vol.19
, pp. 5857
-
-
Mowbray, C.E.1
Burt, C.2
Corbau, R.3
Gayton, S.4
Hawes, M.5
Perros, M.6
Tran, I.7
Price, D.A.8
Quinton, F.J.9
Selby, M.D.10
Stupple, P.A.11
Webster, R.12
Wood, A.13
|