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Volumn 60, Issue , 2013, Pages 120-127
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Discovery of coumarin-monastrol hybrid as potential antibreast tumor-specific agent
a
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Author keywords
Antibreast tumor; Coumarin; Hybrids; Monastrol
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Indexed keywords
ANTINEOPLASTIC AGENT;
CASPASE 3;
COUMARIN DERIVATIVE;
EPIRUBICIN;
ETHYL 4 [3 (3,4 DIMETHOXYPHENYL) 8 METHYL 2 OXO 2H CHROMEN 6 YL] 6 METHYL 2 OXO 1,2,3,4 TETRAHYDROPYRIMIDINE 5 CARBOXYLIC ACID;
ETHYL 4 [3 (3,4 DIMETHOXYPHENYL) 8 METHYL 2 OXO 2H CHROMEN 6 YL] 6 METHYL 2 THIOXO 1,2,3,4 TETRAHYDROPYRIMIDINE 5 CARBOXYLIC ACID;
ETHYL 4 [3 (4 METHOXYPHENYL) 8 METHYL 2 OXO 2H CHROMEN 6 YL] 6 METHYL 2 OXO 1,2,3,4 TETRAHYDROPYRIMIDINE 5 CARBOXYLIC ACID;
ETHYL 4 [3 (4 METHOXYPHENYL) 8 METHYL 2 OXO 2H CHROMEN 6 YL] 6 METHYL 2 THIOXO 1,2,3,4 TETRAHYDROPYRIMIDINE 5 CARBOXYLIC ACID;
ETHYL 4 [8 TERT BUTYL 2 OXO 3 (3,4,5 TRIMETHOXYPHENYL) 2H CHROMEN 6 YL] 6 METHYL 2 THIOXO 1,2,3,4 TETRAHYDROPYRIMIDINE 5 CARBOXYLIC ACID;
ETHYL 6 METHYL 4 [8 METHYL 2 OXO 3 (3,4,5 TRIMETHOXYPHENYL) 2H CHROMEN 6 YL] 2 OXO 1,2,3,4 TETRAHYDROPYRIMIDINE 5 CARBOXYLIC ACID;
ETHYL 6 METHYL 4 [8 METHYL 2 OXO 3 (3,4,5 TRIMETHOXYPHENYL) 2H CHROMEN 6 YL] 2 THIOXO 1,2,3,4 TETRAHYDROPYRIMIDINE 5 CARBOXYLIC ACID;
MONASTROL;
TAMOXIFEN;
UNCLASSIFIED DRUG;
ANTINEOPLASTIC ACTIVITY;
ANTIPROLIFERATIVE ACTIVITY;
APOPTOSIS;
ARTICLE;
BREAST CANCER;
BREAST METASTASIS;
CANCER CELL;
CELL CYCLE G1 PHASE;
CELL CYCLE G2 PHASE;
CELL CYCLE S PHASE;
CELL STRAIN MCF 7;
CELL VIABILITY;
CONTROLLED STUDY;
DRUG SYNTHESIS;
ENZYME ACTIVATION;
ESTROGEN RECEPTOR POSITIVE BREAST CANCER;
HUMAN;
HUMAN CELL;
IC 50;
MOLECULAR HYBRIDIZATION;
PRIMARY TUMOR;
ANTINEOPLASTIC AGENTS;
APOPTOSIS;
BREAST NEOPLASMS;
CELL CYCLE;
CELL PROLIFERATION;
CELL SURVIVAL;
COUMARINS;
DOSE-RESPONSE RELATIONSHIP, DRUG;
DRUG DISCOVERY;
DRUG SCREENING ASSAYS, ANTITUMOR;
FEMALE;
HUMANS;
MCF-7 CELLS;
MOLECULAR STRUCTURE;
PYRIMIDINES;
STRUCTURE-ACTIVITY RELATIONSHIP;
THIONES;
TUMOR CELLS, CULTURED;
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EID: 84871677570
PISSN: 02235234
EISSN: 17683254
Source Type: Journal
DOI: 10.1016/j.ejmech.2012.11.044 Document Type: Article |
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Times cited : (97)
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References (17)
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