Prediction and evaluation of route dependent dosimetry of BPA in rats at different life stages using a physiologically based pharmacokinetic model

Toxicology and Applied Pharmacology

Volumn 270, Issue 1, 2013, Pages 45-59

  Yang, Xiaoxia ^a   Doerge, Daniel R ^a   Fisher, Jeffrey W ^a  

^a NATIONAL CENTER FOR TOXICOLOGICAL RESEARCH   (United States)

Author keywords

Bisphenol A; BPA; Kinetics; PBPK modeling; Rat pups; Rats

Indexed keywords

4,4' ISOPROPYLIDENEDIPHENOL; DRUG METABOLITE;

ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; BILIARY EXCRETION; BLOOD SAMPLING; DOSIMETRY; DRUG BLOOD LEVEL; DRUG EXCRETION; DRUG METABOLISM; FEMALE; LIVER METABOLISM; MALE; METABOLIC CAPACITY; NONHUMAN; PERINATAL PERIOD; RAT; STOMACH EMPTYING; URINARY EXCRETION;

AGE FACTORS; ANIMALS; ANIMALS, NEWBORN; BENZHYDRYL COMPOUNDS; DOSE-RESPONSE RELATIONSHIP, DRUG; DRUG EVALUATION, PRECLINICAL; FEMALE; FORECASTING; LONGEVITY; MALE; MODELS, BIOLOGICAL; PHENOLS; RATS; RATS, SPRAGUE-DAWLEY; TISSUE DISTRIBUTION;

EID: 84877356255     PISSN: 0041008X     EISSN: 10960333     Source Type: Journal    
DOI: 10.1016/j.taap.2013.03.022     Document Type: Article

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