Pharmacokinetic modeling: Prediction and evaluation of route dependent dosimetry of bisphenol A in monkeys with extrapolation to humans

Toxicology and Applied Pharmacology

Volumn 257, Issue 1, 2011, Pages 122-136

  Fisher, Jeffrey W ^a   Twaddle, Nathan C ^a   Vanlandingham, Michelle ^a   Doerge, Daniel R ^a  

^a NATIONAL CENTER FOR TOXICOLOGICAL RESEARCH   (United States)

Author keywords

Bisphenol A; Human; Kinetics; Monkey; PBPK modeling

Indexed keywords

4,4' ISOPROPYLIDENEDIPHENOL; AGLYCONE;

ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; BIOLOGICAL MODEL; BLOOD LEVEL; CONTROLLED STUDY; DOSE CALCULATION; FEMALE; HUMAN; HUMAN VERSUS ANIMAL COMPARISON; INTESTINE WALL; LIVER; MALE; METABOLIC CLEARANCE RATE; METABOLISM; NONHUMAN; PHYSIOLOGICALLY BASED PHARMACOKINETIC MODEL; PREDICTIVE VALUE; RHESUS MONKEY; SIMULATION; TOXICOKINETICS;

ADMINISTRATION, ORAL; AGE FACTORS; ANIMALS; DOSE-RESPONSE RELATIONSHIP, DRUG; FEMALE; HUMANS; INJECTIONS, INTRAVENOUS; INTESTINE, SMALL; LIVER; MACACA MULATTA; MALE; MODELS, BIOLOGICAL; PHENOLS; TISSUE DISTRIBUTION;

MACACA MULATTA; PRIMATES;

EID: 81255149595     PISSN: 0041008X     EISSN: 10960333     Source Type: Journal    
DOI: 10.1016/j.taap.2011.08.026     Document Type: Article

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