Suppression of nuclear factor erythroid 2-related factor 2 via extracellular signal-regulated kinase contributes to bleomycin-induced oxidative stress and fibrogenesis

Toxicology Letters

Volumn 220, Issue 1, 2013, Pages 15-25

  Liu, Rui ^a   Chen, Hongli ^a   Bai, Hua ^a   Zhang, Wei ^a   Wang, Xin ^a   Qin, Xujun ^a   Zhang, Xiaodi ^a   Li, Wenli ^a   liang, Xin ^a   Hai, Chunxu ^a  

^a FOURTH MILITARY MEDICAL UNIVERSITY   (China)

Author keywords

Fibroblast; Nuclear factor erythroid 2 related factor 2; Oxidative stress; Pulmonary fibrosis; Reactive oxygen species

Indexed keywords

BLEOMYCIN; CAFFEIC ACID PHENETHYL ESTER; CATALASE; COLLAGEN; GLUTATHIONE; MITOGEN ACTIVATED PROTEIN KINASE; REACTIVE OXYGEN METABOLITE; SUPEROXIDE DISMUTASE; THIOBARBITURIC ACID REACTIVE SUBSTANCE; TRANSCRIPTION FACTOR NRF2;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CELL PROLIFERATION; CELL VIABILITY; CONTROLLED STUDY; DOWN REGULATION; ENZYME ACTIVITY; ENZYME PHOSPHORYLATION; FIBROGENESIS; LUNG FIBROBLAST; LUNG FIBROSIS; MALE; MOUSE; NONHUMAN; OXIDATIVE STRESS; PRIORITY JOURNAL; REGULATORY MECHANISM;

ANIMALS; ANTIBIOTICS, ANTINEOPLASTIC; BIOLOGICAL MARKERS; BLEOMYCIN; CAFFEIC ACIDS; CELL SURVIVAL; CELLS, CULTURED; COLLAGEN; DISEASE MODELS, ANIMAL; FIBROBLASTS; GENE SILENCING; HYDROXYPROLINE; INTUBATION, INTRATRACHEAL; LIPID PEROXIDATION; MALE; MAP KINASE SIGNALING SYSTEM; MICE; MICE, INBRED C57BL; NF-E2-RELATED FACTOR 2; OXIDATIVE STRESS; OXIDOREDUCTASES; PHENYLETHYL ALCOHOL; PULMONARY FIBROSIS; REACTIVE OXYGEN SPECIES;

EID: 84877352572     PISSN: 03784274     EISSN: 18793169     Source Type: Journal    
DOI: 10.1016/j.toxlet.2013.03.034     Document Type: Article

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