Curcumin inhibits fibrosis-related effects in IPF fibroblasts and in mice following bleomycin-induced lung injury

American Journal of Physiology - Lung Cellular and Molecular Physiology

Volumn 298, Issue 5, 2010, Pages

  Smith, Monica R ^a   Gangireddy, Srinivasa R ^a   Narala, Venkata R ^a   Hogaboam, Cory M ^a   Standiford, Theodore J ^a   Christensen, Paul J ^a,b   Kondapi, Anand K ^c   Reddy, Raju C ^a  

^a UNIVERSITY OF MICHIGAN MEDICAL SCHOOL   (United States)

^b VETERANS AFFAIRS MEDICAL CENTER   (United States)

^c UNIVERSITY OF HYDERABAD   (India)

Author keywords

Extracellular signal regulated kinase; Myofibroblast; Platelet derived growth factor; Smad; Transforming growth factor

Indexed keywords

BLEOMYCIN; COLLAGEN; CURCUMIN; MITOGEN ACTIVATED PROTEIN KINASE 1; MITOGEN ACTIVATED PROTEIN KINASE 3; SMAD2 PROTEIN; SMAD3 PROTEIN; TRANSFORMING GROWTH FACTOR BETA;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CELL DIFFERENTIATION; CELL PROLIFERATION; CONTROLLED STUDY; DRUG ACTIVITY; DRUG BIOAVAILABILITY; DRUG BLOOD LEVEL; FIBROBLAST; FIBROSING ALVEOLITIS; HUMAN; HUMAN CELL; INFLAMMATION; LUNG INJURY; MOUSE; MYOFIBROBLAST; NONHUMAN; PRIORITY JOURNAL; PROTEIN PHOSPHORYLATION;

ADMINISTRATION, ORAL; ANIMALS; BLEOMYCIN; CELL DIFFERENTIATION; CELL PROLIFERATION; CELLS, CULTURED; COLLAGEN; CURCUMIN; EXTRACELLULAR SIGNAL-REGULATED MAP KINASES; FIBROBLASTS; HUMANS; IDIOPATHIC PULMONARY FIBROSIS; INJECTIONS, INTRAPERITONEAL; LUNG INJURY; MICE; MICE, INBRED C57BL; PHOSPHORYLATION; SIGNAL TRANSDUCTION; SMAD PROTEINS; TRANSFORMING GROWTH FACTOR BETA;

EID: 77951551769     PISSN: 10400605     EISSN: 15221504     Source Type: Journal    
DOI: 10.1152/ajplung.00002.2009     Document Type: Article

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