Inhibition of UVB-induced skin phototoxicity by a grape seed extract as modulator of nitrosative stress, ERK/NF-kB signaling pathway and apoptosis, in SKH-1 mice

Food and Chemical Toxicology

Volumn 57, Issue , 2013, Pages 296-306

  Filip, Gabriela Adriana ^a   Postescu, Ion Dan ^b   Bolfa, Pompei ^c   Catoi, Cornel ^c   Muresan, Adriana ^a   Clichici, Simona ^a  

^a IULIU HATIEGANU UNIVERSITY OF MEDICINE AND PHARMACY   (Romania)

^b Prof I Chiricuta Oncologic Institute   (Romania)

^c UNIVERSITY OF AGRICULTURAL SCIENCES AND VETERINARY MEDICINE   (Romania)

Author keywords

Apoptosis; Cell proliferation; Grape seed; Nitrosative stress; Signal transduction

Indexed keywords

3 NITROTYROSINE; BURGUND MARE EXTRACT; CASPASE 3; GRAPE SEED EXTRACT; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; INDUCIBLE NITRIC OXIDE SYNTHASE; MITOGEN ACTIVATED PROTEIN KINASE; MITOGEN ACTIVATED PROTEIN KINASE 1; MITOGEN ACTIVATED PROTEIN KINASE 3; NITRIC OXIDE; POLYPHENOL DERIVATIVE; PROTEIN BCL 2; PROTEIN P53; UNCLASSIFIED DRUG;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ANTIOXIDANT ACTIVITY; APOPTOSIS; ARTICLE; BURGUND MARE; CELL PROLIFERATION; CONTROLLED STUDY; DRUG DETERMINATION; ENZYME ACTIVATION; ENZYME ACTIVITY; ENZYME INHIBITION; ENZYME PHOSPHORYLATION; FEMALE; GRAPE; IMMUNOREACTIVITY; IN VITRO STUDY; IN VIVO STUDY; IRRADIATION; LOW DRUG DOSE; MOUSE; NITRATION; NITROSATIVE STRESS; NONHUMAN; PHOTOTOXICITY; RADIATION DOSE; SIGNAL TRANSDUCTION; SKIN PHOTOTOXICITY; SKIN TOXICITY; ULTRAVIOLET B RADIATION;

ANIMALS; APOPTOSIS; BCL-2-ASSOCIATED X PROTEIN; CASPASE 3; FEMALE; GRAPE SEED EXTRACT; MAP KINASE SIGNALING SYSTEM; MICE; MICE, HAIRLESS; NF-KAPPA B; NITRIC OXIDE; NITRIC OXIDE SYNTHASE TYPE II; RADIATION-PROTECTIVE AGENTS; SIGNAL TRANSDUCTION; SKIN; SKIN DISEASES; TYROSINE; ULTRAVIOLET RAYS;

EID: 84877316391     PISSN: 02786915     EISSN: 18736351     Source Type: Journal    
DOI: 10.1016/j.fct.2013.03.031     Document Type: Article

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