Green tea polyphenol (-)-epigallocatechin-3-gallate treatment to mouse skin prevents UVB-induced infiltration of leukocytes, depletion of antigen-presenting cells, and oxidative stress

Journal of Leukocyte Biology

Volumn 69, Issue 5, 2001, Pages 719-726

  Katiyar, Santosh K ^a,b   Mukhtar, Hasan ^a  

^a CASE WESTERN RESERVE UNIVERSITY SCHOOL OF MEDICINE   (United States)

^b UNIVERSITY OF ALABAMA AT BIRMINGHAM   (United States)

Author keywords

( ) epigallocatechin 3 gallate (EGCG); Antigen presenting cell; Green tea; Immune suppression; Oxidative stress; Ultraviolet radiation

Indexed keywords

CD11B ANTIGEN; EPIGALLOCATECHIN GALLATE; HYDROGEN PEROXIDE; MAJOR HISTOCOMPATIBILITY ANTIGEN CLASS 1; MAJOR HISTOCOMPATIBILITY ANTIGEN CLASS 2; MYELOPEROXIDASE; NITRIC OXIDE;

ANIMAL EXPERIMENT; ANTIGEN PRESENTING CELL; ARTICLE; CARCINOGENESIS; CELL INFILTRATION; CONTROLLED STUDY; ENZYME ACTIVITY; FEMALE; IMMUNE RESPONSE; IMMUNOHISTOCHEMISTRY; IMMUNOSUPPRESSIVE TREATMENT; LEUKOCYTE ACTIVATION; MOUSE; NONHUMAN; OXIDATIVE STRESS; PRIORITY JOURNAL; RADIATION EXPOSURE; RADIATION INJURY; RADIATION PROTECTION; TEA; ULTRAVIOLET B RADIATION;

ANIMALS; ANTIGEN-PRESENTING CELLS; ANTIOXIDANTS; CATECHIN; FEMALE; FLAVONOIDS; HYDROGEN PEROXIDE; LEUKOCYTES; MICE; MICE, INBRED C3H; NEUTROPHIL INFILTRATION; NITRIC OXIDE; NITRIC OXIDE SYNTHASE; NITRIC OXIDE SYNTHASE TYPE II; OXIDATIVE STRESS; PHENOLS; POLYMERS; SKIN; TEA; ULTRAVIOLET RAYS;

EID: 0035011985     PISSN: 07415400     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (48)

1. Agarwal, R., Mukhtar, H. (1993) Oxidative stress in skin chemical carcinogenesis. In Oxidative Stress in Dermatology: (J. Fuchs, L. Packer, ed.). New York, NY, Marcel Dekker, 207-241.
2. Perchellet, J.-P., Perchellet, E. M. (1989) Antioxidants and multistage carcinogenesis in mouse skin. Free Radic. Biol. Med. 7, 377-408.
3. Dragsted, L. O. (1998) Natural antioxidants in chemoprevention. Arch. Toxicol. Suppl. 20, 209-226.
4. Hoeman, G. (1989) Prevention of cancer: vegetables and plants. Comp. Biochem. Physiol. B 93, 201-212.
5. Yang, C. S., Lee, M. J., Chen, L., Yang, G. Y. (1997) Polyphenols as inhibitors of carcinogenesis. Environ. Health Perspect. 105, 971-976.
6. Wattenberg, L. W. (1990) Inhibition of carcinogenesis by naturally occurring and synthetic compounds. In Antimutagenesis and Anticarcinogenesis, Mechanism II, (Y. Kuroda, D. M. Shankel , M. D. Waters, ed.), New York, NY, Plenum Publishing Corp. 155-166.
7. Katiyar, S. K., Mukhtar, H. (1997) Tea antioxidants in cancer chemoprevention. J. Cellular Biochem. 27, 59-67.
8. Miller, D. L., Weinstock, M. A. (1994) Nonmelanoma skin cancer in the United States: incidence. J. Am. Acad. Dermatol. 30, 774-778.
9. Kripke, M. L. (1990) Photoimmunology. Photochem. Photobiol. 52, 919-924.
10. Kligman, L. H., Akin, F. J., Kligman, A. M. (1980) Sunscreens prevent ultraviolet photocarcinogenesis. J. Am. Acad. Dermatol. 3, 30-35.
11. Katiyar, S. K., Korman, N. J., Mukhtar, H., Agarwal, R. (1997) Protective effects of silymarin against photocarcinogenesis in a mouse skin model. J. Natl. Cancer Inst. 89, 556-566.
12. Yoshikawa, T., Rae, V., Bruins-Slot, W., van den Berg, J. W., Taylor, J. R., Streilein, J. W. (1990) Susceptibility to effects of UVB radiation on induction of contact hypersensitivity as a risk factor for skin cancer in humans. J. Invest. Dermatol. 95, 530-536.
13. Donawho, C. K., Muller, H. K., Bucana, C. D., Kripke, M. L. (1996) Enhanced growth of murine melanoma in ultraviolet-irradiated skin is associated with local inhibition of immune effector mechanisms. J. Immunol. 157, 781-786.
14. Toews, G. B., Bergstresser, P. R., Streilein, J. W., Sullivan, S. (1980) Epidermal Langerhans cell density determines whether contact hypersensitivity or unresponsiveness follows skin painting with DNFB. J. Immunol. 124, 445-453.
15. Aberer, W., Schuler, G., Stingl, G., Honigsmann, H., Wolff, K. (1981) Ultraviolet light depletes surface markers of Langerhans cells. J. Invest. Dermatol. 76, 202-210.
16. Noonan, F. P., Bucana, C., Sauder, D. N., DeFabo, E. C. (1984) Mechanism of systemic immune suppression by UV irradiation in vivo. II. The UV effects on number and morphology of epidermal Langerhans cells and the UV-induced suppression of contact hypersensitivity have different wavelength dependencies. J. Immunol. 132, 2408-2416.
17. Moodycliffe, A. M., Kimber, I., Norval, M. (1992) The effect of ultraviolet B irradiation and urocanic acid isomers on dendritic cell migration, Immunology 77, 394-399.
18. Sontag, Y., Guikers, C. L. H., Vink, A. A., de Gruijl, F. R., van Loveren, H., Garssen, J., Roza, L., Kripke, M. L., van der Leun, J. C., van Vloten, W. A. (1995) Cells with UV-specific DNA damage are present in murine lymph nodes after in vivo UV irradiation. J. Invest. Dermatol. 104, 734-738.
19. Tang, A., Udey, M. C. (1992) Effects of ultraviolet radiation on murine epidermal Langerhans cells: doses of ultraviolet radiation that modulate ICAM-1 (CD54) expression and inhibit Langerhans cell function cause delayed cytotoxicity in vitro. J. Invest. Dermatol. 99, 83-89.
20. Cooper, K. D., Duraiswamy, N., Hammerberg, C., Allen, E., Kimbrough-Green, C., Dillon, W., Thomas, D. (1993) Neutrophils, differentiated macrophages, and monocyte/macrophage antigen presenting cells infiltrate murine epidermis after UV injury. J. Invest. Dermatol. 101, 155-163.
21. Hammerberg, C., Duraiswamy, N., Cooper, K. D. (1994) Active induction of unresponsiveness (tolerance) to DNFB by in vivo ultraviolet-exposed epidermal cells is dependent upon infiltrating class II MHC+ CD1lb (bright) monocytic/macrophagic cells. J. Immunol. 153, 4915-4924.
22. Cruz, P. D., Nixon-Fulton, J., Tigelaar, R. E., Bergstresser, P. R. (1989) Disparate effects of in vitro low-dose UVB irradiation on intravenous immunizations with purified epidermal cell subpopulations for the induction of contact hypersensitivity. J. Invest. Dermatol. 92, 160-165.
23. Hammerberg, C., Duraiswamy, N., Cooper, K. D, (1996) Reversal of immunosuppression inducible through ultraviolet-exposed skin by in vivo anti-CD1lb treatment. J. Immunol. 157, 5254-5261.
24. Hammerberg, C., Katiyar, S. K., Carroll, M. C., Cooper K. D. (1998) Activated complement component 3 (C3) is required for ultraviolet induction of immunosuppression and antigenic tolerance. J. Exp. Med. 187, 1133-1138.
25. Pekarek, L. A., Starr, B. A., Toledano, A. Y., Schreiber, H. (1995) Inhibition of tumor growth by elimination of granulocytes. J. Exp. Med. 181, 435-440.
26. Sueng, L. P., Rowley, D. A., Dubey, P., Schreiber, H. (1995) Synergy between T-cell immunity and inhibition of paracrine stimulation causes tumor rejection. Proc. Natl. Acad. Sci. USA 92, 6254-6258.
27. Sueng, L. P., Seung, S. K., Schreiber, H. (1995) Antigenic cancer cells that escape immune destruction are stimulated by host cells. Cancer Res. 55, 5094-5100.
28. Katiyar, S. K., Ahmad, N., Mukhtar, H. (2000) Green tea and skin. Arch. Dermatol. 136, 989-994.
29. Katiyar, S. K., Elmets, C. A., Agarwal, K., Mukhtar, H. (1995) Protection against ultraviolet-B radiation-induced local and systemic suppression of contact hypersensitivity and edema responses in C3H/HeN mice by green tea polyphenols. Photochem. Photobiol. 62, 855-861.
30. Katiyar, S. K., Challa, A., McCormick, T. S., Cooper, K. D., Mukhtar, H. (1999) Prevention of UVB-induced immunosuppression in mice by the green tea polyphenol (-)-epigallocatechin-3-gallate may be associated with alterations in IL-10 and IL-12 production. Carcinogenesis 20, 2117-2124.
31. Learn, D. B., Beard, J., and Moloney, S. J. (1993) The ultraviolet C energy emitted from FS lamps contributes significantly to the induction of human erythema and murine ear edema. Photodermatol. Photoimmunol. Photomed. 9, 147-153.
32. Bradley, P. P., Priebat, D. A., Christensen, R. D., Rothstein, G. (1982) Measurement of cutaneous inflammation: estimation of neutrophil content with an enzyme marker. J. Invest. Dermatol. 78, 206-209.
33. Katiyar, S. K., Matsui, M. S., Elmets, C. A., Mukhtar, H. (1999) Polyphenolic antioxidant (-)-epigallocatechin-3-gallate from green tea reduces UVB-induced inflammatory responses and infiltration of leukocytes in human skin. Photochem. Photobiol. 69, 148-153.
34. Dannenberg, A. M., Jr., Schofield, B. H., Rao, J. B., Dinh, T. T., Lee, K., Boulay, M., Abe, Y., Tsuruta, J., Steinbeck, M. J. (1994) Histochemical demonstration of hydrogen peroxide production by leukocytes in fixed-frozen tissue sections of inflammatory lesions. J. Leukoc. Biol. 56, 436-443.
35. Peus, D., Vasa, R. A., Beyerle, A., Meyes, A., Krautmacher, C. Pittelkow, M. R. (1999) UVB activates ERK1/2 and p38 signaling pathways via reactive oxygen species in cultured keratinocytes. J. Invest. Dermatol. 112, 751-756.
36. 2 in cultured endothelial cells. Arch. Biochem. Biophys. 302, 348-355.
37. Toews, G. B., Bergstresser, P. R., Streilein, J. W., Sullivan, S. (1980) Epidermal Langerhans cell density determines whether contact hypersensitivity or unresponsiveness follows skin painting with DNFB. J. Immunol. 124, 445-453.
38. Greene, M. I., Sy, M. S., Kripke, M. L., Benacerraf, B. (1979) Impairment of antigen presenting cell function by ultraviolet radiation. Proc. Natl. Acad. Sci. USA 76, 6591-6595.
39. Noonan, F. P., Kripke, M. L., Pedersen, G. M., Greene, M. I. (1981) Suppression of contact hypersensitivity in mice by ultraviolet irradiation is associated with defective antigen presentation. Immunology 43, 527-533.
40. Tang, A., Udey, M. C. (1991) Inhibition of epidermal Langerhans cell function by low dose ultraviolet B radiation: ultraviolet B radiation selectively modulates ICAM-1 (CD54) expression by murine Langerhans cells. J. Immunol. 146, 3347-3355.
41. Simon, J. C., Cruz, P. D., Jr., Bergstresser, P. R., Tigelaar, R. E. (1990) Low dose ultraviolet B-irradialed Langerhans cells preferentially activate CD4+ cells of the T helper 2 subset. J. Immunol. 145, 2087-2091.
42. Cooper, K. D., Oberhelman, L., Hamilton, T. A., Baadsgaard, O., Terhune, M., LeVee, G., Anderson, T., Koren, H. (1992) UV exposure reduces immunization rates and promotes tolerance to epicutaneous antigens in humans: relationship to dose, CD1a-DR+ epidermal macrophage induction, and Langerhans cell depletion. Proc. Natl. Acad. Sci. USA 89, 8497-8501.
43. Baadsgaard, O., Fox, D. A., Cooper, K. D. (1988) Human epidermal cells from ultraviolet light-exposed skin preferentially activate autoreactive CD4+ 2H4+ suppressor-inducer lymphocytes and CD8+ suppressor/ cytotoxic lymphocytes. J. Immunol. 140, 1738-1744.
44. Cooper, K. D., Fox, P., Neises, G., Katz, S. I. (1985) Effects of ultraviolet radiation on human epidermal cell alloantigen presentation: initial depression of Langerhans cell-dependent function is followed by the appearance of T6-DR+ cells that enhance epidermal alloantigen presentation. J. Immunol. 134, 129-137.
45. Iwai, I., Hatao, M., Naganuma, M., Kumano, Y., Ichihashi, M. (1999) UVA-induced immune suppression through an oxidative pathway. J. Invest. Dermatol. 112, 19-24.
46. Rosin, M. P., Anwar, W. A., Ward, A. J. (1994) Inflammation, chromosomal instability, and cancer: the schistosomiasis model. Cancer Res. 54 (Suppl.), 1929s-1933s.
47. Trush, M. A., Seed, J. L., Kensler, T. W. (1995) Oxidant-dependent metabolic activation of polycyclic aromatic hydrocarbons by phorbol ester-stimulated human polymorphonuclear leukocytes: Possible link between inflammation and cancer. Proc. Natl. Acad. Sci. USA 82, 5194-5198.
48. Weitzman, S. A., Clark, E. P., Stossel, T. P. (1985) Phagocytes as carcinogens: malignant transformation produced by human neutrophils. Science 227, 1231-1233.