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Volumn 84, Issue 2, 2008, Pages 382-387

Early events in UV carcinogenesis - DNA damage, target cells and mutant p53 foci

Author keywords

[No Author keywords available]

Indexed keywords

PROTEIN P53;

EID: 41049090091     PISSN: 00318655     EISSN: None     Source Type: Journal    
DOI: 10.1111/j.1751-1097.2007.00275.x     Document Type: Review
Times cited : (107)

References (68)
  • 1
    • 0343775713 scopus 로고
    • On nuclear derivatives and lethal action of ultraviolet light
    • Gates, F. L. (1928) On nuclear derivatives and lethal action of ultraviolet light. Science 68, 479 480.
    • (1928) Science , vol.68 , pp. 479-480
    • Gates, F.L.1
  • 2
    • 0000015585 scopus 로고
    • Wavelength dependence of mutation production in the ultraviolet with special emphasis on fungi
    • Hollaender, A. C. W. Emmons (1941) Wavelength dependence of mutation production in the ultraviolet with special emphasis on fungi. Cold Spring Harb. Symp. Quant. Biol. 9, 179 186.
    • (1941) Cold Spring Harb. Symp. Quant. Biol. , vol.9 , pp. 179-186
    • Hollaender, A.1    Emmons, C.W.2
  • 3
    • 33749832874 scopus 로고    scopus 로고
    • Bistability of atmospheric oxygen and the Great Oxidation
    • Goldblatt, C., T. M. Lenton A. J. Watson (2006) Bistability of atmospheric oxygen and the Great Oxidation. Nature 443, 683 686.
    • (2006) Nature , vol.443 , pp. 683-686
    • Goldblatt, C.1    Lenton, T.M.2    Watson, A.J.3
  • 4
    • 33645992474 scopus 로고    scopus 로고
    • Population exposure to ultraviolet radiation in Finland 1920-1995: Exposure trends and a time-series analysis of exposure and cutaneous melanoma incidence
    • Kojo, K., C. T. Jansen, P. Nybom, L. Huurto, J. Laihia, T. Ilus A. Auvinen (2006) Population exposure to ultraviolet radiation in Finland 1920-1995: Exposure trends and a time-series analysis of exposure and cutaneous melanoma incidence. Environ. Res. 101, 123 131.
    • (2006) Environ. Res. , vol.101 , pp. 123-131
    • Kojo, K.1    Jansen, C.T.2    Nybom, P.3    Huurto, L.4    Laihia, J.5    Ilus, T.6    Auvinen, A.7
  • 6
    • 33745762180 scopus 로고    scopus 로고
    • Trends, causes, approach and consequences related to the skin-cancer epidemic in the Netherlands and Europe
    • de Vries, E., J. W. Coebergh H. van der Rhee (2006) Trends, causes, approach and consequences related to the skin-cancer epidemic in the Netherlands and Europe. Ned. Tijdschr. Geneeskd. 150, 1108 1115.
    • (2006) Ned. Tijdschr. Geneeskd. , vol.150 , pp. 1108-1115
    • De Vries, E.1    Coebergh, J.W.2    Van Der Rhee, H.3
  • 7
    • 33749064973 scopus 로고    scopus 로고
    • Trends in sunburns, sun protection practices, and attitudes toward sun exposure protection and tanning among US adolescents, 1998-2004
    • Cokkinides, V., M. Weinstock, K. Glanz, J. Albano, E. Ward M. Thun (2006) Trends in sunburns, sun protection practices, and attitudes toward sun exposure protection and tanning among US adolescents, 1998-2004. Pediatrics 118, 853 864.
    • (2006) Pediatrics , vol.118 , pp. 853-864
    • Cokkinides, V.1    Weinstock, M.2    Glanz, K.3    Albano, J.4    Ward, E.5    Thun, M.6
  • 9
    • 0036440599 scopus 로고    scopus 로고
    • Non-melanoma skin cancer risk in the Queensland renal transplant population
    • Ramsay, H. M., A. A. Fryer, C. M. Hawley, A. G. Smith P. N. Harden (2002) Non-melanoma skin cancer risk in the Queensland renal transplant population. Br. J. Dermatol. 147, 950 956.
    • (2002) Br. J. Dermatol. , vol.147 , pp. 950-956
    • Ramsay, H.M.1    Fryer, A.A.2    Hawley, C.M.3    Smith, A.G.4    Harden, P.N.5
  • 11
    • 0035743141 scopus 로고    scopus 로고
    • Chemoprevention of skin cancer through natural agents
    • Gupta, S. H. Mukhtar (2001) Chemoprevention of skin cancer through natural agents. Skin Pharmacol. Appl. Skin Physiol. 14, 373 385.
    • (2001) Skin Pharmacol. Appl. Skin Physiol. , vol.14 , pp. 373-385
    • Gupta, S.1    Mukhtar, H.2
  • 12
    • 3142676732 scopus 로고    scopus 로고
    • Lupeol modulates NF-kappaB and PI3K/Akt pathways and inhibits skin cancer in CD-1 mice
    • Saleem, M., F. Afaq, V. M. Adhami H. Mukhtar (2004) Lupeol modulates NF-kappaB and PI3K/Akt pathways and inhibits skin cancer in CD-1 mice. Oncogene 23, 5203 5214.
    • (2004) Oncogene , vol.23 , pp. 5203-5214
    • Saleem, M.1    Afaq, F.2    Adhami, V.M.3    Mukhtar, H.4
  • 13
    • 0017848305 scopus 로고
    • Dose response, wavelength dependence and rate of excision of ultraviolet radiation-induced pyrimidine dimers in mouse skin DNA
    • Cooke, A. B. E. Johnson (1978) Dose response, wavelength dependence and rate of excision of ultraviolet radiation-induced pyrimidine dimers in mouse skin DNA. Biochim. Biophys. Acta 517, 24 30.
    • (1978) Biochim. Biophys. Acta , vol.517 , pp. 24-30
    • Cooke, A.1    Johnson, B.E.2
  • 14
    • 0018169617 scopus 로고
    • Formation of thymine containing dimers in skin exposed to ultraviolet radiation
    • Johnson, B. E. (1978) Formation of thymine containing dimers in skin exposed to ultraviolet radiation. Bull. Cancer 65, 283 297.
    • (1978) Bull. Cancer , vol.65 , pp. 283-297
    • Johnson, B.E.1
  • 16
    • 0027980471 scopus 로고
    • Estimate of the wavelength dependency of ultraviolet carcinogenesis in humans and its relevance to the risk assessment of a stratospheric ozone depletion
    • de Gruijl, F. R. J. C. van der Leun (1994) Estimate of the wavelength dependency of ultraviolet carcinogenesis in humans and its relevance to the risk assessment of a stratospheric ozone depletion. Health Phys. 67, 319 325.
    • (1994) Health Phys. , vol.67 , pp. 319-325
    • De Gruijl, F.R.1    Van Der Leun, J.C.2
  • 19
    • 0033372068 scopus 로고    scopus 로고
    • Skin cancer and solar UV radiation
    • de Gruijl, F. R. (1999) Skin cancer and solar UV radiation. Eur. J. Cancer 35, 2003 2009.
    • (1999) Eur. J. Cancer , vol.35 , pp. 2003-2009
    • De Gruijl, F.R.1
  • 20
    • 0024379332 scopus 로고
    • Wavelength dependence of pyrimidine dimer formation in DNA of human skin irradiated in situ with ultraviolet light
    • Freeman, S. E., H. Hacham, R. W. Gange, D. J. Maytum, J. C. Sutherland B. M. Sutherland (1989) Wavelength dependence of pyrimidine dimer formation in DNA of human skin irradiated in situ with ultraviolet light. Proc. Natl Acad. Sci. USA 86, 5605 5609.
    • (1989) Proc. Natl Acad. Sci. USA , vol.86 , pp. 5605-5609
    • Freeman, S.E.1    Hacham, H.2    Gange, R.W.3    Maytum, D.J.4    Sutherland, J.C.5    Sutherland, B.M.6
  • 22
    • 0019990165 scopus 로고
    • UV-induced "mutation hotspots" occur at damage "hotspots."
    • Brash, D. E. W. A. Haseltine (1982) UV-induced "mutation hotspots" occur at damage "hotspots." Nature 298, 189 192.
    • (1982) Nature , vol.298 , pp. 189-192
    • Brash, D.E.1    Haseltine, W.A.2
  • 25
    • 0027414676 scopus 로고
    • Ultraviolet-induced cyclobutane pyrimidine dimers are selectively removed from transcriptionally active genes in the epidermis of the hairless mouse
    • Ruven, H. J., R. J. Berg, C. M. Seelen, J. A. Dekkers, P. H. Lohman, L. H. Mullenders A. A. van Zeeland (1993) Ultraviolet-induced cyclobutane pyrimidine dimers are selectively removed from transcriptionally active genes in the epidermis of the hairless mouse. Cancer Res. 53, 1642 1645.
    • (1993) Cancer Res. , vol.53 , pp. 1642-1645
    • Ruven, H.J.1    Berg, R.J.2    Seelen, C.M.3    Dekkers, J.A.4    Lohman, P.H.5    Mullenders, L.H.6    Van Zeeland, A.A.7
  • 26
    • 0033729135 scopus 로고    scopus 로고
    • Cyclobutane pyrimidine dimers form preferentially at the major p53 mutational hotspot in UVB-induced mouse skin tumors
    • You, Y. H., P. E. Szabo G. P. Pfeifer (2000) Cyclobutane pyrimidine dimers form preferentially at the major p53 mutational hotspot in UVB-induced mouse skin tumors. Carcinogenesis 21, 2113 2117.
    • (2000) Carcinogenesis , vol.21 , pp. 2113-2117
    • You, Y.H.1    Szabo, P.E.2    Pfeifer, G.P.3
  • 27
    • 0031426132 scopus 로고    scopus 로고
    • Wavelength dependence of oxidative DNA damage induced by UV and visible light
    • Kielbassa, C., L. Roza B. Epe (1997) Wavelength dependence of oxidative DNA damage induced by UV and visible light. Carcinogenesis 18, 811 816.
    • (1997) Carcinogenesis , vol.18 , pp. 811-816
    • Kielbassa, C.1    Roza, L.2    Epe, B.3
  • 29
    • 0029071480 scopus 로고
    • Ultraviolet radiation induction of squamous cell carcinomas in p53 transgenic mice
    • Li, G., V. C. Ho, K. Berean V. A. Tron (1995) Ultraviolet radiation induction of squamous cell carcinomas in p53 transgenic mice. Cancer Res. 55, 2070 2074.
    • (1995) Cancer Res. , vol.55 , pp. 2070-2074
    • Li, G.1    Ho, V.C.2    Berean, K.3    Tron, V.A.4
  • 30
    • 0033595088 scopus 로고    scopus 로고
    • P53 protects against skin cancer induction by UV-B radiation
    • Jiang, W., H. N. Ananthaswamy, H. K. Muller M. L. Kripke (1999) p53 protects against skin cancer induction by UV-B radiation. Oncogene 18, 4247 4253.
    • (1999) Oncogene , vol.18 , pp. 4247-4253
    • Jiang, W.1    Ananthaswamy, H.N.2    Muller, H.K.3    Kripke, M.L.4
  • 34
    • 0031045819 scopus 로고    scopus 로고
    • Relative susceptibilities of XPA knockout mice and their heterozygous and wild-type littermates to UVB-induced skin cancer
    • Berg, R. J., A. de Vries, H. van Steeg F. R. de Gruijl (1997) Relative susceptibilities of XPA knockout mice and their heterozygous and wild-type littermates to UVB-induced skin cancer. Cancer Res. 57, 581 584.
    • (1997) Cancer Res. , vol.57 , pp. 581-584
    • Berg, R.J.1    De Vries, A.2    Van Steeg, H.3    De Gruijl, F.R.4
  • 37
    • 0035129781 scopus 로고    scopus 로고
    • Analysis of c-Ha-ras gene mutations in skin tumors induced in carcinogenesis-susceptible and carcinogenesis-resistant mice by different two-stage protocols or tumor promoter alone
    • Pazzaglia, S., M. Mancuso, B. Primerano, S. Rebessi, G. Biozzi, V. Covelli A. Saran (2001) Analysis of c-Ha-ras gene mutations in skin tumors induced in carcinogenesis-susceptible and carcinogenesis-resistant mice by different two-stage protocols or tumor promoter alone. Mol. Carcinog. 30, 111 118.
    • (2001) Mol. Carcinog. , vol.30 , pp. 111-118
    • Pazzaglia, S.1    Mancuso, M.2    Primerano, B.3    Rebessi, S.4    Biozzi, G.5    Covelli, V.6    Saran, A.7
  • 38
    • 0023763189 scopus 로고
    • Absence of induction of enhanced reactivation of herpes simplex virus in cells from xeroderma pigmentosum patients without skin cancer
    • Abrahams, P. J., A. A. van der Kleij, R. Schouten A. J. van der Eb (1988) Absence of induction of enhanced reactivation of herpes simplex virus in cells from xeroderma pigmentosum patients without skin cancer. Cancer Res. 48, 6054 6057.
    • (1988) Cancer Res. , vol.48 , pp. 6054-6057
    • Abrahams, P.J.1    Van Der Kleij, A.A.2    Schouten, R.3    Van Der Eb, A.J.4
  • 39
    • 0030757706 scopus 로고    scopus 로고
    • A lack of radiation-induced ornithine decarboxylase activity prevents enhanced reactivation of herpes simplex virus and is linked to non-cancer proneness in xeroderma pigmentosum patients
    • Terleth, C., T. van Laar, R. Schouten, H. van Steeg, H. Hodemaekers, T. Wormhoudt, P. D. Cornelissen-Steijger, P. J. Abrahams A. J. van der Eb (1997) A lack of radiation-induced ornithine decarboxylase activity prevents enhanced reactivation of herpes simplex virus and is linked to non-cancer proneness in xeroderma pigmentosum patients. Cancer Res. 57, 4384 4392.
    • (1997) Cancer Res. , vol.57 , pp. 4384-4392
    • Terleth, C.1    Van Laar, T.2    Schouten, R.3    Van Steeg, H.4    Hodemaekers, H.5    Wormhoudt, T.6    Cornelissen-Steijger, P.D.7    Abrahams, P.J.8    Van Der Eb, A.J.9
  • 40
    • 0036494267 scopus 로고    scopus 로고
    • Suppression of UV carcinogenesis by difluoromethylornithine in nucleotide excision repair-deficient Xpa knockout mice
    • Rebel, H., H. van Steeg, R. B. Beems, R. Schouten, F. R. de Gruijl C. Terleth (2002) Suppression of UV carcinogenesis by difluoromethylornithine in nucleotide excision repair-deficient Xpa knockout mice. Cancer Res. 62, 1338 1342.
    • (2002) Cancer Res. , vol.62 , pp. 1338-1342
    • Rebel, H.1    Van Steeg, H.2    Beems, R.B.3    Schouten, R.4    De Gruijl, F.R.5    Terleth, C.6
  • 41
    • 0032815072 scopus 로고    scopus 로고
    • Chemopreventive activity of celecoxib, a specific cyclooxygenase-2 inhibitor, and indomethacin against ultraviolet light-induced skin carcinogenesis
    • Fischer, S. M., H. H. Lo, G. B. Gordon, K. Seibert, G. Kelloff, R. A. Lubet C. J. Conti (1999) Chemopreventive activity of celecoxib, a specific cyclooxygenase-2 inhibitor, and indomethacin against ultraviolet light-induced skin carcinogenesis. Mol. Carcinog. 25, 231 240.
    • (1999) Mol. Carcinog. , vol.25 , pp. 231-240
    • Fischer, S.M.1    Lo, H.H.2    Gordon, G.B.3    Seibert, K.4    Kelloff, G.5    Lubet, R.A.6    Conti, C.J.7
  • 42
    • 0032827814 scopus 로고    scopus 로고
    • Reduction of UV-induced skin tumors in hairless mice by selective COX-2 inhibition
    • Pentland, A. P., J. W. Schoggins, G. A. Scott, K. N. Khan R. Han (1999) Reduction of UV-induced skin tumors in hairless mice by selective COX-2 inhibition. Carcinogenesis 20, 1939 1944.
    • (1999) Carcinogenesis , vol.20 , pp. 1939-1944
    • Pentland, A.P.1    Schoggins, J.W.2    Scott, G.A.3    Khan, K.N.4    Han, R.5
  • 43
    • 0030031401 scopus 로고    scopus 로고
    • Early p53 alterations in mouse skin carcinogenesis by UVB radiation: Immunohistochemical detection of mutant p53 protein in clusters of preneoplastic epidermal cells
    • Berg, R. J., H. J. van Kranen, H. G. Rebel, A. de Vries, W. A. van Vloten, C. F. van Kreijl, J. C. van der Leun F. R. de Gruijl (1996) Early p53 alterations in mouse skin carcinogenesis by UVB radiation: Immunohistochemical detection of mutant p53 protein in clusters of preneoplastic epidermal cells. Proc. Natl Acad. Sci. USA 93, 274 278.
    • (1996) Proc. Natl Acad. Sci. USA , vol.93 , pp. 274-278
    • Berg, R.J.1    Van Kranen, H.J.2    Rebel, H.G.3    De Vries, A.4    Van Vloten, W.A.5    Van Kreijl, C.F.6    Van Der Leun, J.C.7    De Gruijl, F.R.8
  • 45
    • 0035114197 scopus 로고    scopus 로고
    • Early p53-positive foci as indicators of tumor risk in ultraviolet-exposed hairless mice: Kinetics of induction, effects of DNA repair deficiency, and p53 heterozygosity
    • Rebel, H., L. O. Mosnier, R. J. Berg, A. Westerman-de Vries, H. van Steeg, H. J. van Kranen F. R. de Gruijl (2001) Early p53-positive foci as indicators of tumor risk in ultraviolet-exposed hairless mice: Kinetics of induction, effects of DNA repair deficiency, and p53 heterozygosity. Cancer Res. 61, 977 983.
    • (2001) Cancer Res. , vol.61 , pp. 977-983
    • Rebel, H.1    Mosnier, L.O.2    Berg, R.J.3    Westerman-De Vries, A.4    Van Steeg, H.5    Van Kranen, H.J.6    De Gruijl, F.R.7
  • 47
    • 0035923598 scopus 로고    scopus 로고
    • Escaping the stem cell compartment: Sustained UVB exposure allows p53-mutant keratinocytes to colonize adjacent epidermal proliferating units without incurring additional mutations
    • Zhang, W., E. Remenyik, D. Zelterman, D. E. Brash N. M. Wikonkal (2001) Escaping the stem cell compartment: Sustained UVB exposure allows p53-mutant keratinocytes to colonize adjacent epidermal proliferating units without incurring additional mutations. Proc. Natl Acad. Sci. USA 98, 13948 13953.
    • (2001) Proc. Natl Acad. Sci. USA , vol.98 , pp. 13948-13953
    • Zhang, W.1    Remenyik, E.2    Zelterman, D.3    Brash, D.E.4    Wikonkal, N.M.5
  • 49
    • 0033223510 scopus 로고    scopus 로고
    • Relationship of p53 mutations to epidermal cell proliferation and apoptosis in human UV-induced skin carcinogenesis
    • Einspahr, J. G., D. S. Alberts, J. A. Warneke, P. Bozzo, J. Basye, T. M. Grogan, M. A. Nelson G. T. Bowden (1999) Relationship of p53 mutations to epidermal cell proliferation and apoptosis in human UV-induced skin carcinogenesis. Neoplasia 1, 468 475.
    • (1999) Neoplasia , vol.1 , pp. 468-475
    • Einspahr, J.G.1    Alberts, D.S.2    Warneke, J.A.3    Bozzo, P.4    Basye, J.5    Grogan, T.M.6    Nelson, M.A.7    Bowden, G.T.8
  • 50
    • 0032497584 scopus 로고    scopus 로고
    • Genetic instability in the 9q22.3 region is a late event in the development of squamous cell carcinomas
    • Ahmadian, A., Z. Ren, C. Williams, F. Ponten, J. Odeberg, J. Ponten, M. Uhlen J. Lundeberg (1998) Genetic instability in the 9q22.3 region is a late event in the development of squamous cell carcinomas. Oncogene 17, 1837 1843.
    • (1998) Oncogene , vol.17 , pp. 1837-1843
    • Ahmadian, A.1    Ren, Z.2    Williams, C.3    Ponten, F.4    Odeberg, J.5    Ponten, J.6    Uhlen, M.7    Lundeberg, J.8
  • 52
    • 27944509203 scopus 로고    scopus 로고
    • Relationship between UV-induced mutant p53 patches and skin tumours, analysed by mutation spectra and by induction kinetics in various DNA-repair-deficient mice
    • Rebel, H., N. Kram, A. Westerman, S. Banus, H. J. van Kranen F. R. de Gruijl (2005) Relationship between UV-induced mutant p53 patches and skin tumours, analysed by mutation spectra and by induction kinetics in various DNA-repair-deficient mice. Carcinogenesis 26, 2123 2130.
    • (2005) Carcinogenesis , vol.26 , pp. 2123-2130
    • Rebel, H.1    Kram, N.2    Westerman, A.3    Banus, S.4    Van Kranen, H.J.5    De Gruijl, F.R.6
  • 53
    • 18144385454 scopus 로고    scopus 로고
    • Patches of mutant p53-immunoreactive epidermal cells induced by chronic UVB irradiation harbor the same p53 mutations as squamous cell carcinomas in the skin of hairless SKH-1 mice
    • Kramata, P., Y. P. Lu, Y. R. Lou, R. N. Singh, S. M. Kwon A. H. Conney (2005) Patches of mutant p53-immunoreactive epidermal cells induced by chronic UVB irradiation harbor the same p53 mutations as squamous cell carcinomas in the skin of hairless SKH-1 mice. Cancer Res. 65, 3577 3585.
    • (2005) Cancer Res. , vol.65 , pp. 3577-3585
    • Kramata, P.1    Lu, Y.P.2    Lou, Y.R.3    Singh, R.N.4    Kwon, S.M.5    Conney, A.H.6
  • 55
    • 0026092280 scopus 로고
    • Development of skin tumors in hairless mice after discontinuation of ultraviolet irradiation
    • de Gruijl, F. R. J. C. van der Leun (1991) Development of skin tumors in hairless mice after discontinuation of ultraviolet irradiation. Cancer Res. 51, 979 984.
    • (1991) Cancer Res. , vol.51 , pp. 979-984
    • De Gruijl, F.R.1    Van Der Leun, J.C.2
  • 56
    • 0142103813 scopus 로고    scopus 로고
    • Antigen-specific immunity does not mediate acute regression of UVB-induced p53-mutant clones
    • Remenyik, E., N. M. Wikonkal, W. Zhang, V. Paliwal D. E. Brash (2003) Antigen-specific immunity does not mediate acute regression of UVB-induced p53-mutant clones. Oncogene 22, 6369 6376.
    • (2003) Oncogene , vol.22 , pp. 6369-6376
    • Remenyik, E.1    Wikonkal, N.M.2    Zhang, W.3    Paliwal, V.4    Brash, D.E.5
  • 58
    • 0016617165 scopus 로고
    • Epidermal transit times
    • Potten, C. S. (1975) Epidermal transit times. Br. J. Dermatol. 93, 649 658.
    • (1975) Br. J. Dermatol. , vol.93 , pp. 649-658
    • Potten, C.S.1
  • 59
    • 34249789291 scopus 로고    scopus 로고
    • Squamous cell carcinoma induced by ultraviolet radiation originates from cells of the hair follicle in mice
    • Faurschou, A., M. Haedersdal, T. Poulsen H. C. Wulf (2007) Squamous cell carcinoma induced by ultraviolet radiation originates from cells of the hair follicle in mice. Exp. Dermatol. 16, 485 489.
    • (2007) Exp. Dermatol. , vol.16 , pp. 485-489
    • Faurschou, A.1    Haedersdal, M.2    Poulsen, T.3    Wulf, H.C.4
  • 61
    • 0034650889 scopus 로고    scopus 로고
    • Evidence that the epidermal targets of carcinogen action are found in the interfollicular epidermis of infundibulum as well as in the hair follicles
    • Morris, R. J., K. A. Tryson K. Q. Wu (2000) Evidence that the epidermal targets of carcinogen action are found in the interfollicular epidermis of infundibulum as well as in the hair follicles. Cancer Res. 60, 226 229.
    • (2000) Cancer Res. , vol.60 , pp. 226-229
    • Morris, R.J.1    Tryson, K.A.2    Wu, K.Q.3
  • 64
    • 35349024815 scopus 로고    scopus 로고
    • Growth stimulation of UV-induced DNA damage retaining epidermal basal cells gives rise to clusters of p53 overexpressing cells
    • Nijhof, J. G., A. A. Mulder, E. N. Speksnijder, E. M. Hoogervorst, L. H. Mullenders F. R. de Gruijl (2007) Growth stimulation of UV-induced DNA damage retaining epidermal basal cells gives rise to clusters of p53 overexpressing cells. DNA Repair 6, 1642 1650.
    • (2007) DNA Repair , vol.6 , pp. 1642-1650
    • Nijhof, J.G.1    Mulder, A.A.2    Speksnijder, E.N.3    Hoogervorst, E.M.4    Mullenders, L.H.5    De Gruijl, F.R.6
  • 65
    • 31544471428 scopus 로고    scopus 로고
    • Ultraviolet irradiation induces keratinocyte proliferation and epidermal hyperplasia through the activation of the epidermal growth factor receptor
    • El-Abaseri, T. B., S. Putta L. A. Hansen (2006) Ultraviolet irradiation induces keratinocyte proliferation and epidermal hyperplasia through the activation of the epidermal growth factor receptor. Carcinogenesis 27, 225 231.
    • (2006) Carcinogenesis , vol.27 , pp. 225-231
    • El-Abaseri, T.B.1    Putta, S.2    Hansen, L.A.3
  • 66
    • 85047690868 scopus 로고
    • CHa-ras proto-oncogene. Amplification and overexpression in UV-B-induced mouse skin papillomas and carcinomas
    • Husain, Z., Q. M. Yang D. K. Biswas (1990) cHa-ras proto-oncogene. Amplification and overexpression in UV-B-induced mouse skin papillomas and carcinomas. Arch. Dermatol. 126, 324 330.
    • (1990) Arch. Dermatol. , vol.126 , pp. 324-330
    • Husain, Z.1    Yang, Q.M.2    Biswas, D.K.3
  • 67
    • 0020451460 scopus 로고
    • Effect of chronic UV exposure on epidermal transmission in mice
    • de Gruijl, F. R. J. C. van der Leun (1982) Effect of chronic UV exposure on epidermal transmission in mice. Photochem. Photobiol. 36, 433 438.
    • (1982) Photochem. Photobiol. , vol.36 , pp. 433-438
    • De Gruijl, F.R.1    Van Der Leun, J.C.2
  • 68
    • 0030772009 scopus 로고    scopus 로고
    • Epidermal proliferation but not quantity of DNA photodamage is correlated with UV-induced mouse skin carcinogenesis
    • Berton, T. R., D. L. Mitchell, S. M. Fischer M. F. Locniskar (1997) Epidermal proliferation but not quantity of DNA photodamage is correlated with UV-induced mouse skin carcinogenesis. J. Invest. Dermatol. 109, 340 347.
    • (1997) J. Invest. Dermatol. , vol.109 , pp. 340-347
    • Berton, T.R.1    Mitchell, D.L.2    Fischer, S.M.3    Locniskar, M.F.4


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.