Chronic inflammatory cardiomyopathy of interferon γoverexpressing transgenic mice is mediated by tumor necrosis factor-α

American Journal of Pathology

Volumn 180, Issue 1, 2012, Pages 73-81

  Torzewski, Michael ^a   Wenzel, Philip ^b   Kleinert, Hartmut ^b   Becker, Christoph ^c   El Masri, Jasmin ^b   Wiese, Elena ^b   Brandt, Moritz ^b   Pautz, Andrea ^b   Twardowski, Laura ^a   Schmitt, Edgar ^b   Münzel, Thomas ^b   Reifenberg, Kurt ^b  

^a ROBERT BOSCH HOSPITAL   (Germany)

^b JOHANNES GUTENBERG UNIVERSITY   (Germany)

^c UNIVERSITY OF ERLANGEN NUREMBERG   (Germany)

Author keywords

[No Author keywords available]

Indexed keywords

GAMMA INTERFERON; GLYCOPROTEIN P 15095; RAG1 PROTEIN; TROPONIN T; TUMOR NECROSIS FACTOR ALPHA;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; CARDIOMYOPATHY; CARDIOTOXICITY; CHRONIC DISEASE; CHRONIC INFLAMMATORY CARDIOMYOPATHY; CONTROLLED STUDY; CYTOKINE PRODUCTION; DENDRITIC CELL; FEMALE; GENE OVEREXPRESSION; HEART LEFT VENTRICLE ENDDIASTOLIC PRESSURE; IMMUNE RESPONSE; LIFESPAN; MACROPHAGE; MALE; MONONUCLEAR CELL; MOUSE; MYOCARDITIS; NONHUMAN; PATHOPHYSIOLOGY; PRIORITY JOURNAL;

ADAPTIVE IMMUNITY; ALANINE TRANSAMINASE; ANIMALS; APOPTOSIS; AUTOIMMUNITY; CHRONIC DISEASE; CYTOKINES; ECHOCARDIOGRAPHY; FEMALE; GENE SILENCING; HEPATITIS; INTERFERON-GAMMA; KAPLAN-MEIER ESTIMATE; MACROPHAGES; MALE; MICE; MICE, TRANSGENIC; MYOCARDITIS; PHENOTYPE; TUMOR NECROSIS FACTOR-ALPHA;

EID: 83455230796     PISSN: 00029440     EISSN: 15252191     Source Type: Journal    
DOI: 10.1016/j.ajpath.2011.09.006     Document Type: Article

References (42)

1. B. Devaux, D. Scholz, A. Hirche, W.P. Klovekorn, J. Schaper Upregulation of cell adhesion molecules and the presence of low grade inflammation in human chronic heart failure Eur Heart J 18 1997 470 479 (Pubitemid 27110479)
2. W.J. Paulus Cytokines and heart failure Heart Fail Monit 1 2000 50 56
3. D. Mari, F. Di Berardino, M. Cugno Chronic heart failure and the immune system Clin Rev Allergy Immunol 23 2002 325 340 (Pubitemid 35178818)
4. G. Torre-Amione Immune activation in chronic heart failure Am J Cardiol 95 2005 3C 8C discussion 38C40C (Pubitemid 40755512)
5. B. Levine, J. Kalman, L. Mayer, H.M. Fillit, M. Packer Elevated circulating levels of tumor necrosis factor in severe chronic heart failure N Engl J Med 323 1990 236 241 (Pubitemid 20225044)
6. S.P. Zhao, L.H. Zeng Elevated plasma levels of tumor necrosis factor in chronic heart failure with cachexia Int J Cardiol 58 1997 257 261
7. M. Rauchhaus, W. Doehner, D.P. Francis, C. Davos, M. Kemp, C. Liebenthal, J. Niebauer, J. Hooper, H.D. Volk, A.J. Coats, S.D. Anker Plasma cytokine parameters and mortality in patients with chronic heart failure Circulation 102 2000 3060 3067
8. T. Kubota, M. Miyagishima, R.J. Alvarez, R. Kormos, W.D. Rosenblum, A.J. Demetris, M.J. Semigran, G.W. Dec, R. Holubkov, C.F. McTiernan, D.L. Mann, A.M. Feldman, D.M. McNamara Expression of proinflammatory cytokines in the failing human heart: comparison of recent-onset and end-stage congestive heart failure J Heart Lung Transplant 19 2000 819 824
9. E. Cunha-Neto, V.J. Dzau, P.D. Allen, D. Stamatiou, L. Benvenutti, M.L. Higuchi, N.S. Koyama, J.S. Silva, J. Kalil, C.C. Liew Cardiac gene expression profiling provides evidence for cytokinopathy as a molecular mechanism in Chagas' disease cardiomyopathy Am J Pathol 167 2005 305 313 (Pubitemid 43026088)
10. T. Kubota, C.F. McTiernan, C.S. Frye, S.E. Slawson, B.H. Lemster, A.P. Koretsky, A.J. Demetris, A.M. Feldman Dilated cardiomyopathy in transgenic mice with cardiac-specific overexpression of tumor necrosis factor-alpha Circ Res 81 1997 627 635 (Pubitemid 27432751)
11. D. Bryant, L. Becker, J. Richardson, J. Shelton, F. Franco, R. Peshock, M. Thompson, B. Giroir Cardiac failure in transgenic mice with myocardial expression of tumor necrosis factor-alpha Circulation 97 1998 1375 1381 (Pubitemid 28182676)
12. D.L. Mann Inflammatory mediators and the failing heart: past, present, and the foreseeable future Circ Res 91 2002 988 998 (Pubitemid 35416635)
13. P. Balakumar, M. Singh Anti-tumour necrosis factor-alpha therapy in heart failure: future directions Basic Clin Pharmacol Toxicol 99 2006 391 397 (Pubitemid 44813905)
14. J. Ma, T. Chen, J. Mandelin, A. Ceponis, N.E. Miller, M. Hukkanen, G.F. Ma, Y.T. Konttinen Regulation of macrophage activation Cell Mol Life Sci 60 2003 2334 2346 (Pubitemid 37487255)
15. K. Reifenberg, H.A. Lehr, M. Torzewski, G. Steige, E. Wiese, I. Kupper, C. Becker, S. Ott, P. Nusser, K. Yamamura, G. Rechtsteiner, T. Warger, A. Pautz, H. Kleinert, A. Schmidt, B. Pieske, P. Wenzel, T. Munzel, J. Lohler Interferon-gamma induces chronic active myocarditis and cardiomyopathy in transgenic mice Am J Pathol 171 2007 463 472 (Pubitemid 47344679)
16. T. Toyonaga, O. Hino, S. Sugai, S. Wakasugi, K. Abe, M. Shichiri, K. Yamamura Chronic active hepatitis in transgenic mice expressing interferon-gamma in the liver Proc Natl Acad Sci U S A 91 1994 614 618 (Pubitemid 24041452)
17. P. Mombaerts, J. Iacomini, R.S. Johnson, K. Herrup, S. Tonegawa, V.E. Papaioannou RAG-1-deficient mice have no mature B and T lymphocytes Cell 68 1992 869 877
18. M. Pasparakis, L. Alexopoulou, V. Episkopou, G. Kollias Immune and inflammatory responses in TNF alpha-deficient mice: a critical requirement for TNF alpha in the formation of primary B cell follicles, follicular dendritic cell networks and germinal centers, and in the maturation of the humoral immune response J Exp Med 184 1996 1397 1411 (Pubitemid 26354696)
19. H. Merkle, P. Nusser, S. Knehr, J. Lohler, J. Barsig, K.I. Yamamura, K. Reifenberg Hepatocytes of double-transgenic mice expressing high levels of hepatitis B virus e antigen and interferon-gamma are not injured by HBeAg specific autoantibodies Arch Virol 145 2000 1081 1098 (Pubitemid 30446102)
20. C. Lowbeer, A.M. Forsberg, S. Tokuno, A.L. Hemdahl, S.A. Gustafsson, G. Valen Cardiac troponin T content in heart and skeletal muscle and in blood samples from ApoE/LDL receptor double knockout mice Clin Chim Acta 344 2004 73 78 (Pubitemid 38626139)
21. P. Chomczynski, N. Sacchi Single-step method of RNA isolation by acid guanidinium thiocyanate-phenol-chloroform extraction Anal Biochem 162 1987 156 159 (Pubitemid 17064313)
22. K.J. Livak, T.D. Schmittgen Analysis of relative gene expression data using real-time quantitative PCR and the 2(-Delta Delta C(T)) Method Methods 25 2001 402 408 (Pubitemid 34164012)
23. A.G. Schmidt, V.J. Kadambi, N. Ball, Y. Sato, R.A. Walsh, E.G. Kranias, B.D. Hoit Cardiac-specific overexpression of calsequestrin results in left ventricular hypertrophy, depressed force-frequency relation and pulsus alternans in vivo J Mol Cell Cardiol 32 2000 1735 1744
24. S. Adams, D.W. O'Neill, N. Bhardwaj Recent advances in dendritic cell biology J Clin Immunol 25 2005 177 188
25. J. Banchereau, V. Pascual, A.K. Palucka Autoimmunity through cytokine-induced dendritic cell activation Immunity 20 2004 539 550 (Pubitemid 38638124)
26. D.N. Cook The role of MIP-1 alpha in inflammation and hematopoiesis J Leukoc Biol 59 1996 61 66 (Pubitemid 26057474)
27. P. Conti, M. DiGioacchino MCP-1 and RANTES are mediators of acute and chronic inflammation Allergy Asthma Proc 22 2001 133 137
28. M. Maurer, E. von Stebut Macrophage inflammatory protein-1 Int J Biochem Cell Biol 36 2004 1882 1886 (Pubitemid 38760018)
29. S.T. Tarzami, R. Cheng, W. Miao, R.N. Kitsis, J.W. Berman Chemokine expression in myocardial ischemia: mIP-2 dependent MCP-1 expression protects cardiomyocytes from cell death J Mol Cell Cardiol 34 2002 209 221 (Pubitemid 35222830)
30. C.W. Younce, K. Wang, P.E. Kolattukudy Hyperglycaemia-induced cardiomyocyte death is mediated via MCP-1 production and induction of a novel zinc-finger protein MCPIP Cardiovasc Res 87 2010 665 674
31. N.R. Veillard, V. Braunersreuther, C. Arnaud, F. Burger, G. Pelli, S. Steffens, F. Mach Simvastatin modulates chemokine and chemokine receptor expression by geranylgeranyl isoprenoid pathway in human endothelial cells and macrophages Atherosclerosis 188 2006 51 58 (Pubitemid 44142533)
32. G. Trinchieri, F. Gerosa Immunoregulation by interleukin-12 J Leukoc Biol 59 1996 505 511 (Pubitemid 26155295)
33. B. Lu, B.J. Rutledge, L. Gu, J. Fiorillo, N.W. Lukacs, S.L. Kunkel, R. North, C. Gerard, B.J. Rollins Abnormalities in monocyte recruitment and cytokine expression in monocyte chemoattractant protein 1-deficient mice J Exp Med 187 1998 601 608 (Pubitemid 28093362)
34. N. Maekawa, H. Wada, T. Kanda, T. Niwa, Y. Yamada, K. Saito, H. Fujiwara, K. Sekikawa, M. Seishima Improved myocardial ischemia/reperfusion injury in mice lacking tumor necrosis factor-alpha J Am Coll Cardiol 39 2002 1229 1235 (Pubitemid 34267430)
35. N. Parameswaran, S. Patial Tumor necrosis factor-α signaling in macrophages Crit Rev Eukaryot Gene Expr 20 2010 87 103
36. V. Vila-del Sol, M.D. Diaz-Munoz, M. Fresno Requirement of tumor necrosis factor alpha and nuclear factor-kappaB in the induction by IFN-gamma of inducible nitric oxide synthase in macrophages J Leukoc Biol 81 2007 272 283 (Pubitemid 46021277)
37. J.J. Boyle, P.L. Weissberg, M.R. Bennett Tumor necrosis factor-alpha promotes macrophage-induced vascular smooth muscle cell apoptosis by direct and autocrine mechanisms Arterioscler Thromb Vasc Biol 23 2003 1553 1558 (Pubitemid 37108197)
38. A. Buisman, J.T. van Dissel, J.A. Langermans, R. van Furth Granulocyte-macrophage colony-stimulating factor is not involved in production of reactive nitrogen intermediates by or toxoplasmastatic activity of gamma interferon-activated murine macrophages Infect Immun 62 1994 1121 1124 (Pubitemid 24065604)
39. Y. Tagawa, K. Sekikawa, Y. Iwakura Suppression of concanavalin A-induced hepatitis in IFN-gamma(-/-) mice, but not in TNF-alpha(-/-) mice: role for IFN-gamma in activating apoptosis of hepatocytes J Immunol 159 1997 1418 1428 (Pubitemid 127484121)
40. B. Bozkurt, S.B. Kribbs, F.J. Clubb Jr, L.H. Michael, V.V. Didenko, P.J. Hornsby, Y. Seta, H. Oral, F.G. Spinale, D.L. Mann Pathophysiologically relevant concentrations of tumor necrosis factor-alpha promote progressive left ventricular dysfunction and remodeling in rats Circulation 97 1998 1382 1391 (Pubitemid 28182677)
41. M. Satoh, M. Nakamura, H. Satoh, H. Saitoh, I. Segawa, K. Hiramori Expression of tumor necrosis factor-alphaconverting enzyme and tumor necrosis factor-alpha in human myocarditis J Am Coll Cardiol 36 2000 1288 1294
42. T. Kubota, M. Miyagishima, C.S. Frye, S.M. Alber, G.S. Bounoutas, T. Kadokami, S.C. Watkins, C.F. McTiernan, A.M. Feldman Overexpression of tumor necrosis factor-alpha activates both anti- and pro-apoptotic pathways in the myocardium J Mol Cell Cardiol 33 2001 1331 1344 (Pubitemid 32613425)