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Volumn 8, Issue , 2013, Pages

Ovarian cancer G protein coupled receptor 1 suppresses cell migration of MCF7 breast cancer cells via a Gα12/13-Rho-Rac1 pathway

Author keywords

Cell migration; G 12 13; MCF7 cells; OGR1; Rac1; Rho

Indexed keywords


EID: 84877308342     PISSN: None     EISSN: 17502187     Source Type: Journal    
DOI: 10.1186/1750-2187-8-6     Document Type: Article
Times cited : (39)

References (41)
  • 1
    • 29044447488 scopus 로고    scopus 로고
    • Two ligands for a GPCR, proton vs lysolipid
    • 10.1111/j.1745-7254.2005.00237.x, 16297340
    • Im DS. Two ligands for a GPCR, proton vs lysolipid. Acta Pharmacol Sin 2005, 26(12):1435-1441. 10.1111/j.1745-7254.2005.00237.x, 16297340.
    • (2005) Acta Pharmacol Sin , vol.26 , Issue.12 , pp. 1435-1441
    • Im, D.S.1
  • 2
    • 24344474845 scopus 로고    scopus 로고
    • Proton-sensing and lysolipid-sensitive G-protein-coupled receptors: A novel type of multi-functional receptors
    • 10.1016/j.cellsig.2005.06.002, 16014326
    • Tomura H. Proton-sensing and lysolipid-sensitive G-protein-coupled receptors: A novel type of multi-functional receptors. Cell Signal 2005, 17(12):1466-1476. 10.1016/j.cellsig.2005.06.002, 16014326.
    • (2005) Cell Signal , vol.17 , Issue.12 , pp. 1466-1476
    • Tomura, H.1
  • 3
    • 0042322842 scopus 로고    scopus 로고
    • Proton-sensing G-protein-coupled receptors
    • 10.1038/nature01905, 12955148
    • Ludwig MG. Proton-sensing G-protein-coupled receptors. Nature 2003, 425(6953):93-98. 10.1038/nature01905, 12955148.
    • (2003) Nature , vol.425 , Issue.6953 , pp. 93-98
    • Ludwig, M.G.1
  • 4
    • 5644250571 scopus 로고    scopus 로고
    • G2A is a proton-sensing G-protein-coupled receptor antagonized by lysophosphatidylcholine
    • 10.1074/jbc.M406561200, 15280385
    • Murakami N. G2A is a proton-sensing G-protein-coupled receptor antagonized by lysophosphatidylcholine. J Biol Chem 2004, 279(41):42484-42491. 10.1074/jbc.M406561200, 15280385.
    • (2004) J Biol Chem , vol.279 , Issue.41 , pp. 42484-42491
    • Murakami, N.1
  • 5
    • 8544247246 scopus 로고    scopus 로고
    • TDAG8 is a proton-sensing and psychosine-sensitive G-protein-coupled receptor
    • 10.1074/jbc.M406966200, 15326175
    • Wang JQ. TDAG8 is a proton-sensing and psychosine-sensitive G-protein-coupled receptor. J Biol Chem 2004, 279(44):45626-45633. 10.1074/jbc.M406966200, 15326175.
    • (2004) J Biol Chem , vol.279 , Issue.44 , pp. 45626-45633
    • Wang, J.Q.1
  • 6
    • 66549126410 scopus 로고    scopus 로고
    • Abnormalities in Osteoclastogenesis and Decreased Tumorigenesis in Mice Deficient for Ovarian Cancer G Protein-Coupled Receptor 1
    • 10.1371/journal.pone.0005705, 2684630, 19479052
    • Li H. Abnormalities in Osteoclastogenesis and Decreased Tumorigenesis in Mice Deficient for Ovarian Cancer G Protein-Coupled Receptor 1. PLoS One 2009, 4(5):e5705. 10.1371/journal.pone.0005705, 2684630, 19479052.
    • (2009) PLoS One , vol.4 , Issue.5
    • Li, H.1
  • 7
    • 33846912184 scopus 로고    scopus 로고
    • Vascular abnormalities in mice deficient for the G protein-coupled receptor GPR4 that functions as a pH sensor
    • 10.1128/MCB.01909-06, 1800706, 17145776
    • Yang LV. Vascular abnormalities in mice deficient for the G protein-coupled receptor GPR4 that functions as a pH sensor. Mol Cell Biol 2007, 27(4):1334-1347. 10.1128/MCB.01909-06, 1800706, 17145776.
    • (2007) Mol Cell Biol , vol.27 , Issue.4 , pp. 1334-1347
    • Yang, L.V.1
  • 8
    • 30644478470 scopus 로고    scopus 로고
    • Normal immune development and glucocorticoid-induced thymocyte apoptosis in mice deficient for the T-Cell death-associated gene 8 receptor
    • 10.1128/MCB.26.2.668-677.2006, 1346912, 16382156
    • Radu CG. Normal immune development and glucocorticoid-induced thymocyte apoptosis in mice deficient for the T-Cell death-associated gene 8 receptor. Mol Cell Biol 2006, 26(2):668-677. 10.1128/MCB.26.2.668-677.2006, 1346912, 16382156.
    • (2006) Mol Cell Biol , vol.26 , Issue.2 , pp. 668-677
    • Radu, C.G.1
  • 9
    • 0033772419 scopus 로고    scopus 로고
    • Sphingosylphosphorylcholine is a ligand for ovarian cancer G-protein-coupled receptor 1 (vol 2, pg 261, 2000)
    • Xu Y, Zhu K. Sphingosylphosphorylcholine is a ligand for ovarian cancer G-protein-coupled receptor 1 (vol 2, pg 261, 2000). Nat Cell Biol 2000, 2(8):E146-E146.
    • (2000) Nat Cell Biol , vol.2 , Issue.8
    • Xu, Y.1    Zhu, K.2
  • 10
    • 85044708370 scopus 로고    scopus 로고
    • Sphingosylphosphorylcholine and lysophosphatidylcholine are ligands for the G protein-coupled receptor GPR4. (Retraction of vol 276, pg 41325, 2001)
    • Zhu K. Sphingosylphosphorylcholine and lysophosphatidylcholine are ligands for the G protein-coupled receptor GPR4. (Retraction of vol 276, pg 41325, 2001). J Biol Chem 2005, 280(52):43280-43280.
    • (2005) J Biol Chem , vol.280 , Issue.52 , pp. 43280-43280
    • Zhu, K.1
  • 11
    • 0035897409 scopus 로고    scopus 로고
    • Identification of a molecular target of psychosine and its role in globoid cell formation
    • 10.1083/jcb.153.2.429, 2169470, 11309421
    • Im DS. Identification of a molecular target of psychosine and its role in globoid cell formation. J Cell Biol 2001, 153(2):429-434. 10.1083/jcb.153.2.429, 2169470, 11309421.
    • (2001) J Cell Biol , vol.153 , Issue.2 , pp. 429-434
    • Im, D.S.1
  • 12
    • 28844451017 scopus 로고    scopus 로고
    • Identification of 9-hydroxyoctadecadienoic acid and other oxidized free fatty acids as ligands of the G protein-coupled receptor G2A
    • 10.1074/jbc.M507787200, 16236715
    • Obinata H. Identification of 9-hydroxyoctadecadienoic acid and other oxidized free fatty acids as ligands of the G protein-coupled receptor G2A. J Biol Chem 2005, 280(49):40676-40683. 10.1074/jbc.M507787200, 16236715.
    • (2005) J Biol Chem , vol.280 , Issue.49 , pp. 40676-40683
    • Obinata, H.1
  • 13
    • 34548587161 scopus 로고    scopus 로고
    • Ovarian cancer G protein-coupled receptor 1, a new metastasis suppressor gene in prostate cancer
    • 10.1093/jnci/djm107, 17728215
    • Singh LS. Ovarian cancer G protein-coupled receptor 1, a new metastasis suppressor gene in prostate cancer. J Natl Cancer Inst 2007, 99(17):1313-1327. 10.1093/jnci/djm107, 17728215.
    • (2007) J Natl Cancer Inst , vol.99 , Issue.17 , pp. 1313-1327
    • Singh, L.S.1
  • 14
    • 20944433323 scopus 로고    scopus 로고
    • GPR4 plays a critical role in endothelial cell function and mediates the effects of sphingosylphosphorylcholine
    • Kim K. GPR4 plays a critical role in endothelial cell function and mediates the effects of sphingosylphosphorylcholine. FASEB J 2005, 19(2):819.
    • (2005) FASEB J , vol.19 , Issue.2 , pp. 819
    • Kim, K.1
  • 15
    • 79960149834 scopus 로고    scopus 로고
    • Somatostatin receptors in non-neuroendocrine malignancies: the potential role of somatostatin analogs in solid tumors
    • 10.2217/fon.11.66, 21732759
    • Hasskarl J, Kaufmann M, Schmid HA. Somatostatin receptors in non-neuroendocrine malignancies: the potential role of somatostatin analogs in solid tumors. Future Oncol 2011, 7(7):895-913. 10.2217/fon.11.66, 21732759.
    • (2011) Future Oncol , vol.7 , Issue.7 , pp. 895-913
    • Hasskarl, J.1    Kaufmann, M.2    Schmid, H.A.3
  • 16
    • 79955935862 scopus 로고    scopus 로고
    • Effects of ovarian cancer G protein coupled receptor 1 on the proliferation, migration, and adhesion of human ovarian cancer cells
    • Ren J, Zhang L. Effects of ovarian cancer G protein coupled receptor 1 on the proliferation, migration, and adhesion of human ovarian cancer cells. Chin Med J 2011, 124(9):1327-1332.
    • (2011) Chin Med J , vol.124 , Issue.9 , pp. 1327-1332
    • Ren, J.1    Zhang, L.2
  • 17
    • 33748994545 scopus 로고    scopus 로고
    • Rho GTPases and actin dynamics in membrane protrusions and vesicle trafficking
    • 10.1016/j.tcb.2006.08.006, 16949823
    • Ridley AJ. Rho GTPases and actin dynamics in membrane protrusions and vesicle trafficking. Trends Cell Biol 2006, 16(10):522-529. 10.1016/j.tcb.2006.08.006, 16949823.
    • (2006) Trends Cell Biol , vol.16 , Issue.10 , pp. 522-529
    • Ridley, A.J.1
  • 18
    • 0034644603 scopus 로고    scopus 로고
    • Localized Rac activation dynamics visualized in living cells
    • 10.1126/science.290.5490.333, 11030651
    • Kraynov VS. Localized Rac activation dynamics visualized in living cells. Science 2000, 290(5490):333-337. 10.1126/science.290.5490.333, 11030651.
    • (2000) Science , vol.290 , Issue.5490 , pp. 333-337
    • Kraynov, V.S.1
  • 19
    • 0345731237 scopus 로고    scopus 로고
    • Cell migration: Rho GTPases lead the way
    • 10.1016/j.ydbio.2003.06.003, 14697350
    • Raftopoulou M, Hall A. Cell migration: Rho GTPases lead the way. Dev Biol 2004, 265(1):23-32. 10.1016/j.ydbio.2003.06.003, 14697350.
    • (2004) Dev Biol , vol.265 , Issue.1 , pp. 23-32
    • Raftopoulou, M.1    Hall, A.2
  • 20
    • 0033577975 scopus 로고    scopus 로고
    • Interplay between Rac and Rho in the control of substrate contact dynamics
    • 10.1016/S0960-9822(99)80286-3, 10375527
    • Rottner K, Hall A, Small JV. Interplay between Rac and Rho in the control of substrate contact dynamics. Curr Biol 1999, 9(12):640-648. 10.1016/S0960-9822(99)80286-3, 10375527.
    • (1999) Curr Biol , vol.9 , Issue.12 , pp. 640-648
    • Rottner, K.1    Hall, A.2    Small, J.V.3
  • 21
    • 0035858878 scopus 로고    scopus 로고
    • Nascent focal adhesions are responsible for the generation of strong propulsive forces in migrating fibroblasts
    • 10.1083/jcb.153.4.881, 2192381, 11352946
    • Beningo KA. Nascent focal adhesions are responsible for the generation of strong propulsive forces in migrating fibroblasts. J Cell Biol 2001, 153(4):881-887. 10.1083/jcb.153.4.881, 2192381, 11352946.
    • (2001) J Cell Biol , vol.153 , Issue.4 , pp. 881-887
    • Beningo, K.A.1
  • 22
    • 0035661651 scopus 로고    scopus 로고
    • Distinct roles of frontal and rear cell-substrate adhesions in fibroblast migration
    • 60767, 11739792
    • Munevar S, Wang YL, Dembo M. Distinct roles of frontal and rear cell-substrate adhesions in fibroblast migration. Mol Biol Cell 2001, 12(12):3947-3954. 60767, 11739792.
    • (2001) Mol Biol Cell , vol.12 , Issue.12 , pp. 3947-3954
    • Munevar, S.1    Wang, Y.L.2    Dembo, M.3
  • 23
    • 0035158377 scopus 로고    scopus 로고
    • RhoA inactivation by p190RhoGAP regulates cell spreading and migration by promoting membrane protrusion and polarity
    • 59706, 11553710
    • Arthur WT, Burridge K. RhoA inactivation by p190RhoGAP regulates cell spreading and migration by promoting membrane protrusion and polarity. Mol Biol Cell 2001, 12(9):2711-2720. 59706, 11553710.
    • (2001) Mol Biol Cell , vol.12 , Issue.9 , pp. 2711-2720
    • Arthur, W.T.1    Burridge, K.2
  • 24
    • 0344758986 scopus 로고    scopus 로고
    • Regulation of cell polarity and protrusion formation by targeting RhoA for degradation
    • 10.1126/science.1090772, 14657501
    • Wang HR. Regulation of cell polarity and protrusion formation by targeting RhoA for degradation. Science 2003, 302(5651):1775-1779. 10.1126/science.1090772, 14657501.
    • (2003) Science , vol.302 , Issue.5651 , pp. 1775-1779
    • Wang, H.R.1
  • 25
    • 0038037737 scopus 로고    scopus 로고
    • RhoA and ROCK promote migration by limiting membrane protrusions
    • 10.1074/jbc.M211584200, 12574166
    • Worthylake RA, Burridge K. RhoA and ROCK promote migration by limiting membrane protrusions. J Biol Chem 2003, 278(15):13578-13584. 10.1074/jbc.M211584200, 12574166.
    • (2003) J Biol Chem , vol.278 , Issue.15 , pp. 13578-13584
    • Worthylake, R.A.1    Burridge, K.2
  • 26
    • 0028986034 scopus 로고
    • The Ras-related protein cdc42hs and bradykinin promote formation of peripheral actin microspikes and filopodia in swiss 3t3 fibroblasts
    • 230420, 7891688
    • Kozma R. The Ras-related protein cdc42hs and bradykinin promote formation of peripheral actin microspikes and filopodia in swiss 3t3 fibroblasts. Mol Cell Biol 1995, 15(4):1942-1952. 230420, 7891688.
    • (1995) Mol Cell Biol , vol.15 , Issue.4 , pp. 1942-1952
    • Kozma, R.1
  • 27
    • 0028961293 scopus 로고
    • Rho, Rac, and Cdc42 Gtpases regulate the assembly of multimolecular focal complexes associated with actin stress fibers, lamellipodia
    • Nobes CD, Hall A. Rho, Rac, and Cdc42 Gtpases regulate the assembly of multimolecular focal complexes associated with actin stress fibers, lamellipodia. Filopodia Cell 1995, 81(1):53-62.
    • (1995) Filopodia Cell , vol.81 , Issue.1 , pp. 53-62
    • Nobes, C.D.1    Hall, A.2
  • 28
    • 57649238681 scopus 로고    scopus 로고
    • TCDD induces cell migration via NFATc1/ATX-signaling in MCF-7 cells
    • 10.1016/j.toxlet.2008.10.026, 19028555
    • Seifert A. TCDD induces cell migration via NFATc1/ATX-signaling in MCF-7 cells. Toxicol Lett 2009, 184(1):26-32. 10.1016/j.toxlet.2008.10.026, 19028555.
    • (2009) Toxicol Lett , vol.184 , Issue.1 , pp. 26-32
    • Seifert, A.1
  • 29
    • 25844457390 scopus 로고    scopus 로고
    • Sphingosine kinase 1 is required for migration, proliferation and survival of MCF-7 human breast cancer cells
    • 10.1016/j.febslet.2005.08.055, 16194537
    • Sarkar S. Sphingosine kinase 1 is required for migration, proliferation and survival of MCF-7 human breast cancer cells. FEBS Lett 2005, 579(24):5313-5317. 10.1016/j.febslet.2005.08.055, 16194537.
    • (2005) FEBS Lett , vol.579 , Issue.24 , pp. 5313-5317
    • Sarkar, S.1
  • 30
    • 84855188299 scopus 로고    scopus 로고
    • Reduced pathological angiogenesis and tumor growth in mice lacking GPR4, a proton sensing receptor
    • 10.1007/s10456-011-9238-9, 22045552
    • Wyder L. Reduced pathological angiogenesis and tumor growth in mice lacking GPR4, a proton sensing receptor. Angiogenesis 2011, 14(4):533-544. 10.1007/s10456-011-9238-9, 22045552.
    • (2011) Angiogenesis , vol.14 , Issue.4 , pp. 533-544
    • Wyder, L.1
  • 31
    • 0036488510 scopus 로고    scopus 로고
    • RHO-GTPases and cancer
    • 10.1038/nrc725, 12635176
    • Sahai E, Marshall CJ. RHO-GTPases and cancer. Nat Rev Cancer 2002, 2(2):133. 10.1038/nrc725, 12635176.
    • (2002) Nat Rev Cancer , vol.2 , Issue.2 , pp. 133
    • Sahai, E.1    Marshall, C.J.2
  • 32
    • 0037370012 scopus 로고    scopus 로고
    • Inhibitory and stimulatory regulation of Rac and cell motility by the G(12/13)-Rho and G(i) pathways integrated downstream of a single G protein-coupled sphingosine-1-phosphate receptor isoform
    • 10.1128/MCB.23.5.1534-1545.2003, 151702, 12588974
    • Sugimoto N. Inhibitory and stimulatory regulation of Rac and cell motility by the G(12/13)-Rho and G(i) pathways integrated downstream of a single G protein-coupled sphingosine-1-phosphate receptor isoform. Mol Cell Biol 2003, 23(5):1534-1545. 10.1128/MCB.23.5.1534-1545.2003, 151702, 12588974.
    • (2003) Mol Cell Biol , vol.23 , Issue.5 , pp. 1534-1545
    • Sugimoto, N.1
  • 33
    • 0042858413 scopus 로고    scopus 로고
    • Ligand-dependent inhibition of B16 melanoma cell migration and invasion via endogenous S1P(2) G protein-coupled receptor - Requirement of inhibition of cellular Rac activity
    • 10.1074/jbc.M305024200, 12810709
    • Arikawa K. Ligand-dependent inhibition of B16 melanoma cell migration and invasion via endogenous S1P(2) G protein-coupled receptor - Requirement of inhibition of cellular Rac activity. J Biol Chem 2003, 278(35):32841-32851. 10.1074/jbc.M305024200, 12810709.
    • (2003) J Biol Chem , vol.278 , Issue.35 , pp. 32841-32851
    • Arikawa, K.1
  • 34
    • 37549049395 scopus 로고    scopus 로고
    • S1P(2) receptors mediate inhibition of glioma cell migration through Rho signaling pathways independent of PTEN
    • 10.1016/j.bbrc.2007.12.054, 18088600
    • Malchnkhuu E. S1P(2) receptors mediate inhibition of glioma cell migration through Rho signaling pathways independent of PTEN. Biochem Biophys Res Commun 2008, 366(4):963-968. 10.1016/j.bbrc.2007.12.054, 18088600.
    • (2008) Biochem Biophys Res Commun , vol.366 , Issue.4 , pp. 963-968
    • Malchnkhuu, E.1
  • 35
    • 18144420388 scopus 로고    scopus 로고
    • The G protein-coupled receptor S1P(2) regulates Rho/Rho kinase pathway to inhibit tumor cell migration
    • 10.1158/0008-5472.CAN-04-2311, 15867375
    • Lepley D. The G protein-coupled receptor S1P(2) regulates Rho/Rho kinase pathway to inhibit tumor cell migration. Cancer Res 2005, 65(9):3788-3795. 10.1158/0008-5472.CAN-04-2311, 15867375.
    • (2005) Cancer Res , vol.65 , Issue.9 , pp. 3788-3795
    • Lepley, D.1
  • 36
    • 15444373513 scopus 로고    scopus 로고
    • PTEN as an effector in the signaling of antimigratory G protein-coupled receptor
    • 10.1073/pnas.0409784102, 555509, 15764699
    • Sanchez T. PTEN as an effector in the signaling of antimigratory G protein-coupled receptor. Proc Natl Acad Sci USA 2005, 102(12):4312-4317. 10.1073/pnas.0409784102, 555509, 15764699.
    • (2005) Proc Natl Acad Sci USA , vol.102 , Issue.12 , pp. 4312-4317
    • Sanchez, T.1
  • 37
    • 52449133460 scopus 로고    scopus 로고
    • G(12/13) and G(q) mediate S1P(2)-induced inhibition of Rac and migration in vascular smooth muscle in a manner dependent on Rho but not Rho kinase
    • 10.1093/cvr/cvn118, 18480127
    • Takashima S. G(12/13) and G(q) mediate S1P(2)-induced inhibition of Rac and migration in vascular smooth muscle in a manner dependent on Rho but not Rho kinase. Cardiovasc Res 2008, 79(4):689-697. 10.1093/cvr/cvn118, 18480127.
    • (2008) Cardiovasc Res , vol.79 , Issue.4 , pp. 689-697
    • Takashima, S.1
  • 38
    • 57149147490 scopus 로고    scopus 로고
    • ROCK-regulated cytoskeletal dynamics participate in the inhibitory effect of melatonin on cancer cell migration
    • 10.1111/j.1600-079X.2008.00600.x, 18482340
    • Ortiz-Lopez L. ROCK-regulated cytoskeletal dynamics participate in the inhibitory effect of melatonin on cancer cell migration. J Pineal Res 2009, 46(1):15-21. 10.1111/j.1600-079X.2008.00600.x, 18482340.
    • (2009) J Pineal Res , vol.46 , Issue.1 , pp. 15-21
    • Ortiz-Lopez, L.1
  • 39
    • 35948937181 scopus 로고    scopus 로고
    • Oligodendrocyte lineage transcription factor 2 inhibits the motility of a human glial tumor cell line by activating RhoA
    • 10.1158/1541-7786.MCR-07-0096, 17951409
    • Tabu K. Oligodendrocyte lineage transcription factor 2 inhibits the motility of a human glial tumor cell line by activating RhoA. Mol Cancer Res 2007, 5(10):1099-1109. 10.1158/1541-7786.MCR-07-0096, 17951409.
    • (2007) Mol Cancer Res , vol.5 , Issue.10 , pp. 1099-1109
    • Tabu, K.1
  • 40
    • 0026778133 scopus 로고
    • The small GTP-binding protein rho regulates the assembly of focal adhesions and actin stress fibers in response to growth-factors
    • 10.1016/0092-8674(92)90163-7, 1643657
    • Ridley AJ, Hall A. The small GTP-binding protein rho regulates the assembly of focal adhesions and actin stress fibers in response to growth-factors. Cell 1992, 70(3):389-399. 10.1016/0092-8674(92)90163-7, 1643657.
    • (1992) Cell , vol.70 , Issue.3 , pp. 389-399
    • Ridley, A.J.1    Hall, A.2
  • 41
    • 27344451242 scopus 로고    scopus 로고
    • Sphingosylphosphorylcholine antagonizes proton-sensing ovarian cancer G-protein-coupled receptor 1 (OGR1)-mediated inositol phosphate production and cAMP accumulation
    • 10.1254/jphs.FP0050599, 16210776
    • Mogi C. Sphingosylphosphorylcholine antagonizes proton-sensing ovarian cancer G-protein-coupled receptor 1 (OGR1)-mediated inositol phosphate production and cAMP accumulation. J Pharmacol Sci 2005, 99(2):160-167. 10.1254/jphs.FP0050599, 16210776.
    • (2005) J Pharmacol Sci , vol.99 , Issue.2 , pp. 160-167
    • Mogi, C.1


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